Navigating Flu, COVID-19, and RSV Season: 2026 Symptoms
During winter, it seems like COVID-19, influenza, and Respiratory Syncytial Virus (RSV) are always on the rise. Staying informed is essential to maintaining your and your family's health.
Dr. David Dobrzynski, an infectious disease expert with UR Medicine, answers your questions about vaccines, symptoms, and preventative measures.
Can I get COVID, flu, and RSV vaccines at the same time?
It's safe to receive the COVID-10, flu, and RSV vaccines simultaneously. However, some people might feel unwell after receiving more than one vaccine at once. Dr. Dobrzynski recommends speaking to your primary care doctor to determine what's best for you.
Who should get the flu vaccine?
The flu vaccine is recommended for everyone, especially during the fall and winter. It's never too late to get vaccinated.
“We strongly encourage people to get annual flu shots, COVID boosters, and the RSV vaccine if eligible. Despite potential feelings of vaccine fatigue, our community members should resume normal practices of getting flu vaccines every year,” said Infectious Disease specialist Angela Branche, MD.
Who should get the COVID vaccine?
Everyone should strongly consider getting the COVID-19 vaccine to protect themselves and others from severe disease. The vaccines were recently updated to include the latest circulating variant to help provide better protection.Interested in learning about our clinical trials?
At the University of Rochester Medical Center, we’re at the forefront of finding new ways to prevent and treat infectious diseases. The Infectious Disease Research Clinic (IDRC) conducts different types of health research studies concerning a variety of infections, including flu.
Who should get the RSV vaccine?
- Individuals over 60 years old with increased risk factors (heart or lung disease, immunocompromised conditions)
- Everyone over 75 years old
- Pregnant individuals between 32-36 weeks
"While you can get the RSV vaccine at any time of the year, late summer/early fall is best," said Dr. Dobrzynski.
Do babies need the RSV vaccine?
In 2023, a new RSV immunization called nirsevimab was made available for infants. The CDC and the American Academy of Pediatrics recommend administering the vaccine in the first 8 months of life.
Nirsevimab is given to all infants born in the hospital during respiratory virus season (October to March). Parents of children 0-8 months who have not received the vaccine can also ask their pediatrician for availability.
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Recognizing Symptoms: Differentiating Between RSV, Flu, and COVID-19
The symptoms of RSV, flu, and COVID-19 often overlap, making it challenging to distinguish between them. Common symptoms include:
- Fever
- Cough
- Shortness of breath
- Fatigue
- Body aches
Certain symptoms are more common in one virus or the other. For instance, loss of taste or smell is more commonly associated with COVID-19.
If you experience any of these symptoms, it's crucial to consult a healthcare provider for appropriate testing and guidance.
What to Know About New COVID-19 Variants in 2026
New COVID-19 variants continue to emerge, including recently identified strain BA.3.2, nicknamed "cicada." While some variants may spread more easily, there is no evidence that they cause more severe illness in most people.
Symptoms remain similar to other COVID-19 strains and can overlap with flu and RSV—such as cough, fever, fatigue, and sore throat—making testing important if you feel sick.
Current vaccines and boosters continue to provide strong protection against severe illness, hospitalization, and death.
Can you be sick with all three illnesses at once?
While getting two or three of all three respiratory viruses at the same time is fairly rare, it is technically possible. In general, people only come down with one at a time.
Do I still need to worry about COVID?
Cases of COVID-19 continue to circulate throughout our community. Be sure to get boosted for COVID-19 if you are due. If you recently had COVID-19, the CDC says to consider waiting three months before getting the COVID booster. If you are feeling ill from COVID-19, there are options for symptom relief.
“Call your primary care physician to discuss Paxlovid or molnupiravir. Both medications are more widely available than they once were,” said Dr. Branche.
If you have additional questions, reach out to your primary care physician or chat with a provider via Virtual Urgent Care.
Cold, Flu, and RSV Guide 2026
As we move into winter, illnesses like flu, RSV, COVID-19, and stomach bugs become more common. Stay updated on flu, RSV, and other seasonal illnesses: symptoms, prevention tips, and when to seek care.