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Jennifer Barnas, M.D., Ph.D.

Jennifer Barnas, M.D., Ph.D.

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Contact

Rheumatology Appointment (585) 486-0901
Allergy/Immunology Appointment (585) 486-0930

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About Me

Dr. Jennifer L. Barnas has medical board certifications in internal medicine, allergy/immunology, and rheumatology. She sees patients in both rheumatology and allergy/immunology at the Lattimore Road office (585-486-0901 for rheumatology patients and 585-486-0930 for allergy/immunology patients).
Dr. Jennifer L. Barnas has medical board certifications in internal medicine, allergy/immunology, and rheumatology. She sees patients in both rheumatology and allergy/immunology at the Lattimore Road office (585-486-0901 for rheumatology patients and 585-486-0930 for allergy/immunology patients).

Faculty Appointments

Assistant Professor - Department of Medicine, Allergy/Immunology and Rheumatology (SMD)

Credentials

Post-doctoral Training & Residency

Fellowship, Allergy & Immunology, University of Rochester Medical Center. 2014 - 2018

Residency, Internal Medicine, University of Rochester Medical Center. 2013 - 2014

Internship, Internal Medicine, University of Rochester Medical Center. 2012 - 2013

Education

MD | University at Buffalo. 2012

PhD | University at Buffalo. 2012

Awards

AAI Early Career Faculty Travel Grant. 2020

Master Class in the SLE Basic and Clinical Sciences Attendee. 2018

Eugene A. Gorzynski Travel Award. 2008

Ernest Witebsky Memorial Award for Proficiency in Microbiology. 2007

American Society of Animal Science Scholarship Award. 2000

Research

Research interests of Dr. Barnas include the influence of interferon on human B cell biology as well as the cellular interactions within the renal microenvironment of lupus nephritis and how this contributes to the pathophysiology of human systemic lupus.
Research interests of Dr. Barnas include the influence of interferon on human B cell biology as well as the cellular interactions within the renal microenvironment of lupus nephritis and how this contributes to the pathophysiology of human systemic lupus.

Publications

Journal Articles

Serum soluble mediator signatures of lupus nephritis: histological features and response to treatment.

Fava A, Wagner CA, Guthridge CJ, Macwana S, DeJager W, Munroe ME, Izmirly P, Belmont HM, Diamond B, Davidson A, Utz PJ, Weisman MH, Carlucci PM, Dall'Era M, Kalunian K, Putterman C, Anolik J, Barnas JL, Wofsy D, Kamen D, Furie RA, Rao DA, Petri M, Guthridge JM, Buyon J, James JA

Arthritis care & research.. 2025 October 6 Epub 10/06/2025.

Blood immunophenotyping identifies distinct kidney histopathology and outcomes in patients with lupus nephritis.

Horisberger A, Griffith A, Keegan J, Arazi A, Pulford J, Murzin E, Howard K, Hancock B, Fava A, Sasaki T, Ghosh T, Inamo J, Beuschel R, Cao Y, Preisinger K, Gutierrez-Arcelus M, Eisenhaure TM, Guthridge J, Hoover PJ, Dall'Era M, Wofsy D, Kamen DL, Kalunian KC, Furie R, Belmont M, Izmirly P, Clancy R, Hildeman D, Woodle ES, Apruzzese W, McMahon MA, Grossman J, Barnas JL, Payan-Schober F, Ishimori M, Weisman M, Kretzler M, Berthier CC, Hodgin JB, Demeke DS, Putterman C, Brenner MB, Anolik JH, Raychaudhuri S, Hacohen N, James JA, Davidson A, Petri MA, Buyon JP, Diamond B, Zhang F, Lederer JA, Rao DA

The Journal of clinical investigation.. 2025 August 15135 (16)Epub 06/19/2025.

Extrarenal symptoms associate with worse quality of life in patients enrolled in the AMP RA/SLE Lupus Nephritis Network.

Carlucci PM, Preisinger K, Deonaraine KK, Zaminski D, Dall'Era M, Gold HT, Kalunian K, Fava A, Belmont HM, Wu M, Putterman C, Anolik J, Barnas JL, Furie R, Diamond B, Davidson A, Wofsy D, Kamen D, James JA, Guthridge JM, Apruzzese W, Rao D, Weisman MH, , Izmirly PM, Buyon J, Petri M

Rheumatology.. 2025 March 164 (3):1193-1200. Epub 1900 01 01.

Tissue-specific enhancer-gene maps from multimodal single-cell data identify causal disease alleles.

Sakaue S, Weinand K, Isaac S, Dey KK, Jagadeesh K, Kanai M, Watts GFM, Zhu Z, , Brenner MB, McDavid A, Donlin LT, Wei K, Price AL, Raychaudhuri S

Nature genetics.. 2024 April 56 (4):615-626. Epub 04/09/2024.

Blood immunophenotyping identifies distinct kidney histopathology and outcomes in patients with lupus nephritis.

Horisberger A, Griffith A, Keegan J, Arazi A, Pulford J, Murzin E, Howard K, Hancock B, Fava A, Sasaki T, Ghosh T, Inamo J, Beuschel R, Cao Y, Preisinger K, Gutierrez-Arcelus M, Eisenhaure TM, Guthridge J, Hoover PJ, Dall'Era M, Wofsy D, Kamen DL, Kalunian KC, Furie R, Belmont M, Izmirly P, Clancy R, Hildeman D, Woodle ES, Apruzzese W, McMahon MA, Grossman J, Barnas JL, Payan-Schober F, Ishimori M, Weisman M, Kretzler M, Berthier CC, Hodgin JB, Demeke DS, Putterman C, , Brenner MB, Anolik JH, Raychaudhuri S, Hacohen N, James JA, Davidson A, Petri MA, Buyon JP, Diamond B, Zhang F, Lederer JA, Rao DA

bioRxiv : the preprint server for biology.. 2024 March 9 Epub 03/09/2024.

Longitudinal patterns and predictors of response to standard-of-care therapy in lupus nephritis: data from the Accelerating Medicines Partnership Lupus Network.

Izmirly PM, Kim MY, Carlucci PM, Preisinger K, Cohen BZ, Deonaraine K, Zaminski D, Dall'Era M, Kalunian K, Fava A, Belmont HM, Wu M, Putterman C, Anolik J, Barnas JL, Diamond B, Davidson A, Wofsy D, Kamen D, James JA, Guthridge JM, Apruzzese W, Rao DA, Weisman MH, , Petri M, Buyon J, Furie R

Arthritis research & therapy.. 2024 February 2026 (1):54. Epub 02/20/2024.

Urine proteomic signatures of histological class, activity, chronicity, and treatment response in lupus nephritis.

Fava A, Buyon J, Magder L, Hodgin J, Rosenberg A, Demeke DS, Rao DA, Arazi A, Celia AI, Putterman C, Anolik JH, Barnas J, Dall'Era M, Wofsy D, Furie R, Kamen D, Kalunian K, James JA, Guthridge J, Atta MG, Monroy Trujillo J, Fine D, Clancy R, Belmont HM, Izmirly P, Apruzzese W, Goldman D, Berthier CC, Hoover P, Hacohen N, Raychaudhuri S, Davidson A, Diamond B, , Petri M

JCI insight.. 2024 January 239 (2)Epub 01/23/2024.

Editorial: Treat-to-target in systemic lupus erythematosus: cytokine transduction pathways in SLE.

Nozaki Y, Hao Y, Barnas JL

Frontiers in immunology.. 2024 15 :1503776. Epub 10/16/2024.

Interferon activation in bone marrow long-lived plasma cells in systemic lupus erythematosus.

Alzamareh DF, Meednu N, Nandedkar-Kulkarni N, Krenitsky D, Barnard J, Yasaka K, Durrett W, Thakar J, Rangel-Moreno J, Anolik JH, Barnas JL

Frontiers in immunology.. 2024 15 :1499551. Epub 01/10/2025.

Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes.

Zhang F, Jonsson AH, Nathan A, Millard N, Curtis M, Xiao Q, Gutierrez-Arcelus M, Apruzzese W, Watts GFM, Weisenfeld D, Nayar S, Rangel-Moreno J, Meednu N, Marks KE, Mantel I, Kang JB, Rumker L, Mears J, Slowikowski K, Weinand K, Orange DE, Geraldino-Pardilla L, Deane KD, Tabechian D, Ceponis A, Firestein GS, Maybury M, Sahbudin I, Ben-Artzi A, Mandelin AM, Nerviani A, Lewis MJ, Rivellese F, Pitzalis C, Hughes LB, Horowitz D, DiCarlo E, Gravallese EM, Boyce BF, , Moreland LW, Goodman SM, Perlman H, Holers VM, Liao KP, Filer A, Bykerk VP, Wei K, Rao DA, Donlin LT, Anolik JH, Brenner MB, Raychaudhuri S

Nature.. 2023 November 623 (7987):616-624. Epub 11/08/2023.

High incidence of proliferative and membranous nephritis in SLE patients with low proteinuria in the Accelerating Medicines Partnership.

Carlucci PM, Li J, Fava A, Deonaraine KK, Wofsy D, James JA, Putterman C, Diamond B, Davidson A, Fine DM, Monroy-Trujillo J, Atta MG, DeJager W, Guthridge JM, Haag K, Rao DA, Brenner MB, Lederer JA, Apruzzese W, Belmont HM, Izmirly PM, Zaminski D, Wu M, Connery S, Payan-Schober F, Furie R, Dall'Era M, Cho K, Kamen D, Kalunian K, Anolik J, Barnas J, Ishimori M, Weisman MH, , Buyon JP, Petri M

Rheumatology.. 2022 November 261 (11):4335-4343. Epub 1900 01 01.

B Cell Activation and Plasma Cell Differentiation Are Promoted by IFN-? in Systemic Lupus Erythematosus.

Barnas JL, Albrecht J, Meednu N, Alzamareh DF, Baker C, McDavid A, Looney RJ, Anolik JH

The Journal of immunology : official journal of the American Association of Immunologists.. 2021 December 1207 (11):2660-2672. Epub 10/27/2021.

Safety of procuring research tissue during a clinically indicated kidney biopsy from patients with lupus: data from the Accelerating Medicines Partnership RA/SLE Network.

Deonaraine KK, Carlucci PM, Fava A, Li J, Wofsy D, James JA, Putterman C, Diamond B, Davidson A, Fine DM, Monroy-Trujillo J, Atta MG, Haag K, Rao DA, Apruzzese W, Belmont HM, Izmirly PM, Wu M, Connery S, Payan-Schober F, Furie RA, Berthier CC, Dall'Era M, Cho K, Kamen DL, Kalunian K, Anolik J, Ishimori M, Weisman MH, , Petri MA, Buyon JP

Lupus science & medicine.. 2021 August 8 (1)Epub 1900 01 01.

B cell targeted therapies in autoimmune disease.

Barnas JL, Looney RJ, Anolik JH

Current opinion in immunology.. 2019 December 61 :92-99. Epub 11/14/2019.

Transitional B cells in quiescent SLE: An early checkpoint imprinted by IFN.

Dieudonné Y, Gies V, Guffroy A, Keime C, Bird AK, Liesveld J, Barnas JL, Poindron V, Douiri N, Soulas-Sprauel P, Martin T, Meffre E, Anolik JH, Korganow AS

Journal of autoimmunity.. 2019 August 102 :150-158. Epub 05/10/2019.

Correction to: Cell Senescence in Lupus.

Gao L, Slack M, Barnas JL, McDavid A, Anolik J, Looney RJ

Current rheumatology reports.. 2019 May 2321 (7):32. Epub 05/23/2019.

Etiology and Pathogenesis of Psoriatic Arthritis.

Barnas JL, Ritchlin CT

Rheumatic diseases clinics of North America.. 2015 November 41 (4):643-63. Epub 08/30/2015.

Human ovarian tumor ascites fluids rapidly and reversibly inhibit T cell receptor-induced NF-?B and NFAT signaling in tumor-associated T cells.

Simpson-Abelson MR, Loyall JL, Lehman HK, Barnas JL, Minderman H, O'Loughlin KL, Wallace PK, George TC, Peng P, Kelleher RJ, Odunsi K, Bankert RB

Cancer immunity. 2013 13 :14. Epub 07/15/2013.

Humanized mouse model of ovarian cancer recapitulates patient solid tumor progression, ascites formation, and metastasis.

Bankert RB, Balu-Iyer SV, Odunsi K, Shultz LD, Kelleher RJ, Barnas JL, Simpson-Abelson M, Parsons R, Yokota SJ

PloS one.. 2011 6 (9):e24420. Epub 09/15/2011.

p53-Associated Parkin-like cytoplasmic protein (Parc) short-interfering RNA (siRNA) alters p53 location and biology of Peyronie's disease fibroblasts.

Mulhall JP, Barnas J, Kobylarz K, Mueller A

BJU international.. 2010 December 106 (11):1706-13. Epub 1900 01 01.

Reciprocal functional modulation of the activation of T lymphocytes and fibroblasts derived from human solid tumors.

Barnas JL, Simpson-Abelson MR, Brooks SP, Kelleher RJ, Bankert RB

The Journal of immunology : official journal of the American Association of Immunologists.. 2010 September 1185 (5):2681-92. Epub 08/04/2010.

T cells and stromal fibroblasts in human tumor microenvironments represent potential therapeutic targets.

Barnas JL, Simpson-Abelson MR, Yokota SJ, Kelleher RJ, Bankert RB

Cancer microenvironment : official journal of the International Cancer Microenvironment Society.. 2010 March 313 (1):29-47. Epub 03/31/2010.

Vasculogenic erectile dysfunction is a predictor of abnormal stress echocardiography.

Mulhall J, Teloken P, Barnas J

The journal of sexual medicine.. 2009 March 6 (3):820-5. Epub 01/09/2009.

The utility of tamsulosin in the management of orgasm-associated pain: a pilot analysis.

Barnas J, Parker M, Guhring P, Mulhall JP

European urology.. 2005 March 47 (3):361-5; discussion 365. Epub 12/16/2004.

Sildenafil citrate response correlates with the nature and the severity of penile vascular insufficiency.

Mulhall J, Barnas J, Aviv N, Anderson M, Parker M

The journal of sexual medicine.. 2005 January 2 (1):104-8. Epub 1900 01 01.

Cosegregation of a factor VIII microsatellite marker with mild hemophilia A in Golden Retriever dogs.

Brooks MB, Barnas JL, Fremont J, Ray J

Journal of veterinary internal medicine. 2005 19 (2):205-10. Epub 1900 01 01.

The prevalence and nature of orgasmic dysfunction after radical prostatectomy.

Barnas JL, Pierpaoli S, Ladd P, Valenzuela R, Aviv N, Parker M, Waters WB, Flanigan RC, Mulhall JP

BJU international.. 2004 September 94 (4):603-5. Epub 1900 01 01.

A Line 1 insertion in the Factor IX gene segregates with mild hemophilia B in dogs.

Brooks MB, Gu W, Barnas JL, Ray J, Ray K

Mammalian genome : official journal of the International Mammalian Genome Society.. 2003 November 14 (11):788-95. Epub 1900 01 01.

Books

Lahita's Systemic Lupus Erythematosus (2021)

Chapter: Chapter 5: B-cell biology, tolerance, and autoantibodies

Authors: Barnas JL, Meffre E, Anolik JH.

Publisher: Elsevier 2021