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Peter A. Prieto, M.D., M.P.H.

Peter A. Prieto, M.D., M.P.H.

Breast Surgery, Surgery, Cancer


Appointment (585) 275-1611

Research Lab


160 Sawgrass Dr
Rochester, NY 14620-4656

125 Red Creek Dr, Bldg 100, Ste 211
Rochester, NY 14623-4262

Wilmot Cancer Institute

601 Elmwood Ave
Rochester, NY 14642-0001

About Me

Professional Background

A native of New York, Dr. Peter A. Prieto chose to dedicate his life to conquering cancer after losing his father to sarcoma. Dr. Prieto, completed his general surgery residency at Yale University School of Medicine where he took three years off and completed a surgical oncology research fellowship...
A native of New York, Dr. Peter A. Prieto chose to dedicate his life to conquering cancer after losing his father to sarcoma. Dr. Prieto, completed his general surgery residency at Yale University School of Medicine where he took three years off and completed a surgical oncology research fellowship and a one of its kind immunotherapy fellowship in the surgery branch of the National Cancer Institute, National Institutes of Health under the mentorship of Dr. Steven A. Rosenberg where he was co-investigator on numerous clinical trials.

He went on to complete his chief residency at Yale and then completed a two year clinical complex surgical oncology fellowship at the prestigious and consistently ranked #1 Cancer Center in the United States, University of Texas MD Anderson Cancer Center in Houston, Texas where he spent an additional year doing a post-doctoral research fellowship under the mentorship of Drs. Jennifer A. Wargo and Funda Meric-Bernstam. At MD Anderson Dr. Prieto was instrumental in the development and analysis of a novel phase II trial looking at neoadjuvant targeted therapy in high-risk resectable stage III BRAF mutant melanoma, which has changed the practice in this challenging patient population.

Dr. Prieto is triple board certified in complex general surgical oncology, general surgery and medical quality. As a fully trained tumor immunotherapist and surgical oncologist, he has expertise in the treatment of primary, regionally advanced and metastatic melanoma, soft tissue sarcoma and breast cancer. His research interests and laboratory investigate mechanisms of immune evasion by solid tumors to targeted and immune checkpoint blockade and prognostic markers of response to immune based therapies including adoptive cell therapy (including melanoma, sarcoma, cholangiocarcinoma and breast cancer).

Dr. Prieto serves on the Society of Surgical Oncology's Sarcoma Disease Site Workgroup Committee and is the Cancer Center Physician Liason to the American College of Surgeons Committee on Cancer.

In addition to authoring numerous high impact publications, Dr. Prieto is the recipient of several prestigious awards and honors. He frequently presents on topics related to surgical oncology and melanoma at the national and international levels. Dr. Prieto's personal mission is to treat all of his patients as if they were his own family.

Certified Specialties

Surgery (General Surgery) - American Board of Surgery

Faculty Appointments

Adjunct Assistant Professor - Department of Surgery, Oncology (SMD)



MD | St. George's University School of Medicine. Medicine. 2006

MPH | St. George's University School of Medicine. Public Health. 2006

BA | State University of New York at Stony Brook. Anthropology. 1999


Seymour I. Schwartz Faculty Excellence in Teaching. 2018

Lotzova Excellence in Research Award, Department of Surgical Oncology. 2017

W. G. Stuber Research Fellowship Grant. 2017 - 2018

Lotzova Excellence in Research Award, Department of Surgical Oncology. 2016

Excellence in Junior Resident Teaching Award. 2014

Sam Harvey Award for Most Outstanding Chief Resident in Surgery. 2014

Excellence In Medical Student Teaching Award. 2013

Arnold P. Gold Humanism Honor Society. 2006

Research Career for Minority Scholars (RCMS). 1994



Journal Articles

H-Scan Discrimination for Tumor Microenvironmental Heterogeneity in Melanoma.

Baek J, Qin SS, Prieto PA, Parker KJ

Ultrasound in medicine & biology.. 2023 November 21 Epub 11/21/2023.

Breast reconstruction with latissimus dorsi flap: a comprehensive review and case series.

Escandón JM, Manrique OJ, Christiano JG, Mroueh V, Prieto PA, Gooch JC, Weiss A, Langstein HN

Annals of translational medicine.. 2023 August 3011 (10):355. Epub 05/24/2023.

Predictors for Prolonged TE-to-Implant Exchange During Implant-Based Breast Reconstruction: A Single Institution Experience.

Escandón JM, Langstein HN, Christiano JG, Gooch JC, Prieto PA, Aristizábal A, Weiss A, Manrique OJ

Aesthetic plastic surgery.. 2023 August 10 Epub 08/10/2023.

RE: A Clinical Decision Tool to Calculate Pretest Probability of Sentinel Lymph Node Metastasis in Primary Cutaneous Melanoma.

Prieto PA, Goldberg MS, Martin B

Annals of surgical oncology.. 2023 July 3 Epub 07/03/2023.

Wise-Pattern versus Transverse Pattern Mastectomy in Two-Stage Implant-Based Breast Reconstruction: A Propensity Score-Matched Analysis.

Escandón JM, Butterfield JA, Christiano JG, Gooch JC, Olzinski AT, Prieto PA, Skinner KA, Langstein HN, Manrique OJ

Plastic and reconstructive surgery.. 2023 May 22 Epub 05/22/2023.

Two-Stage Implant-Based Breast Reconstruction Using Intraoperative Fluorescence Imaging: A Propensity Score-Matched Analysis.

Escandón JM, Christiano JG, Gooch JC, Olzinski AT, Prieto PA, Skinner KA, Langstein HN, Manrique OJ

Plastic and reconstructive surgery.. 2023 April 26 Epub 04/26/2023.

Simultaneous Fat Grafting During Tissue Expander-to-Implant Exchange: A Propensity Score-Matched Analysis.

Escandón JM, Ali-Khan S, Christiano JG, Gooch JC, Olzinski AT, Prieto PA, Skinner KA, Langstein HN, Manrique OJ

Aesthetic plastic surgery.. 2022 October 21 Epub 10/21/2022.

Subpectoral versus prepectoral two-stage breast reconstruction: A propensity score-matched analysis of 30-day morbidity and long-term outcomes.

Escandón JM, Sweitzer K, Christiano JG, Gooch JC, Olzinski AT, Prieto PA, Skinner KA, Langstein HN, Manrique OJ

Journal of plastic, reconstructive & aesthetic surgery : JPRAS.. 2022 October 1976 :76-87. Epub 10/19/2022.

Reconstruction of Pharyngolaryngeal Defects with the Ileocolon Free Flap: A Comprehensive Review and How to Optimize Outcomes.

Escandón JM, Santamaría E, Prieto PA, Duarte-Bateman D, Ciudad P, Pencek M, Langstein HN, Chen HC, Manrique OJ

Archives of plastic surgery.. 2022 May 49 (3):378-396. Epub 05/27/2022.

An analysis of the COVID-19 vaccination campaigns in France, Israel, Italy and Spain and their impact on health and economic outcomes.

Antonini M, Eid MA, Falkenbach M, Rosenbluth ST, Prieto PA, Brammli-Greenberg S, McMeekin P, Paolucci F

Health policy and technology.. 2021 December 24 :100594. Epub 12/24/2021.

Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade.

Andrews MC, Duong CPM, Gopalakrishnan V, Iebba V, Chen WS, Derosa L, Khan MAW, Cogdill AP, White MG, Wong MC, Ferrere G, Fluckiger A, Roberti MP, Opolon P, Alou MT, Yonekura S, Roh W, Spencer CN, Curbelo IF, Vence L, Reuben A, Johnson S, Arora R, Morad G, Lastrapes M, Baruch EN, Little L, Gumbs C, Cooper ZA, Prieto PA, Wani K, Lazar AJ, Tetzlaff MT, Hudgens CW, Callahan MK, Adamow M, Postow MA, Ariyan CE, Gaudreau PO, Nezi L, Raoult D, Mihalcioiu C, Elkrief A, Pezo RC, Haydu LE, Simon JM, Tawbi HA, McQuade J, Hwu P, Hwu WJ, Amaria RN, Burton EM, Woodman SE, Watowich S, Diab A, Patel SP, Glitza IC, Wong MK, Zhao L, Zhang J, Ajami NJ, Petrosino J, Jenq RR, Davies MA, Gershenwald JE, Futreal PA, Sharma P, Allison JP, Routy B, Zitvogel L, Wargo JA

Nature medicine.. 2021 July 8 Epub 07/08/2021.

COVID-19 mRNA vaccine-related adenopathy mimicking metastatic melanoma.

Prieto PA, Mannava K, Sahasrabudhe DM

The Lancet. Oncology.. 2021 June 22 (6):e281. Epub 1900 01 01.

Intertumoral Genetic Heterogeneity Generates Distinct Tumor Microenvironments in a Novel Murine Synchronous Melanoma Model.

Qin SS, Han BJ, Williams A, Jackson KM, Jewell R, Chacon AC, Lord EM, Linehan DC, Kim M, Reuben A, Gerber SA, Prieto PA

Cancers.. 2021 May 1113 (10)Epub 05/11/2021.

Picomets: Assessing single and few cell metastases in melanoma sentinel lymph node biopsies.

Jackso K, Ruffolo L, Kozakiewicz L, Qin SS, Chacon AC, Jewell R, Belt B, Scott GA, Linehan DC, Galka E, Prieto PA

Surgery.. 2021 April 23 Epub 04/23/2021.

Adoptive T Cell Therapy for Solid Tumors: Pathway to Personalized Standard of Care.

Qin SS, Melucci AD, Chacon AC, Prieto PA

Cells.. 2021 April 510 (4)Epub 04/05/2021.

Thinking Small: Small Molecules as Potential Synergistic Adjuncts to Checkpoint Inhibition in Melanoma.

Chacon AC, Melucci AD, Qin SS, Prieto PA

International journal of molecular sciences.. 2021 March 2222 (6)Epub 03/22/2021.

Determination of Casein Allergens in Extensively Hydrolyzed Casein Infant Formula by Liquid Chromatography - Tandem Mass Spectrometry.

Hostetler GL, Barber CM, Miklus MB, Prieto PA

Journal of AOAC International.. 2020 October 16 Epub 10/16/2020.

Microspheres Encapsulating Immunotherapy Agents Target the Tumor-Draining Lymph Node in Pancreatic Ductal Adenocarcinoma.

Han BJ, Murphy JD, Qin S, Ye J, Uccello TP, Garrett-Larsen J, Belt BA, Prieto PA, Egilmez NK, Lord EM, Linehan DC, Mills BN, Gerber SA

Immunological investigations.. 2020 June 4 :1-16. Epub 06/04/2020.

Toxic epidermal necrolysis after radiotherapy for pleomorphic liposarcoma.

Esaa FS, Hobson JG, Matar RN, Prieto PA, Somers KE

Dermatology online journal.. 2020 January 1526 (1)Epub 01/15/2020.

Stereotactic Body Radiation and Interleukin-12 Combination Therapy Eradicates Pancreatic Tumors by Repolarizing the Immune Microenvironment.

Mills BN, Connolly KA, Ye J, Murphy JD, Uccello TP, Han BJ, Zhao T, Drage MG, Murthy A, Qiu H, Patel A, Figueroa NM, Johnston CJ, Prieto PA, Egilmez NK, Belt BA, Lord EM, Linehan DC, Gerber SA

Cell reports.. 2019 October 829 (2):406-421.e5. Epub 1900 01 01.

Neoadjuvant systemic therapy in melanoma: recommendations of the International Neoadjuvant Melanoma Consortium.

Amaria RN, Menzies AM, Burton EM, Scolyer RA, Tetzlaff MT, Antdbacka R, Ariyan C, Bassett R, Carter B, Daud A, Faries M, Fecher LA, Flaherty KT, Gershenwald JE, Hamid O, Hong A, Kirkwood JM, Lo S, Margolin K, Messina J, Postow MA, Rizos H, Ross MI, Rozeman EA, Saw RPM, Sondak V, Sullivan RJ, Taube JM, Thompson JF, van de Wiel BA, Eggermont AM, Davies MA, , Ascierto PA, Spillane AJ, van Akkooi ACJ, Wargo JA, Blank CU, Tawbi HA, Long GV

The Lancet. Oncology.. 2019 July 20 (7):e378-e389. Epub 1900 01 01.

High-grade angiosarcoma presenting with cytology-negative hemorrhagic ascites.

Patel AP, Peacock JL, Prieto PA

Journal of surgical case reports.. 2018 October 2018 (10):rjy273. Epub 10/11/2018.

Neoadjuvant plus adjuvant dabrafenib and trametinib versus standard of care in patients with high-risk, surgically resectable melanoma: a single-centre, open-label, randomised, phase 2 trial.

Amaria RN, Prieto PA, Tetzlaff MT, Reuben A, Andrews MC, Ross MI, Glitza IC, Cormier J, Hwu WJ, Tawbi HA, Patel SP, Lee JE, Gershenwald JE, Spencer CN, Gopalakrishnan V, Bassett R, Simpson L, Mouton R, Hudgens CW, Zhao L, Zhu H, Cooper ZA, Wani K, Lazar A, Hwu P, Diab A, Wong MK, McQuade JL, Royal R, Lucci A, Burton EM, Reddy S, Sharma P, Allison J, Futreal PA, Woodman SE, Davies MA, Wargo JA

The Lancet. Oncology.. 2018 February 19 (2):181-193. Epub 01/18/2018.

Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients.

Gopalakrishnan V, Spencer CN, Nezi L, Reuben A, Andrews MC, Karpinets TV, Prieto PA, Vicente D, Hoffman K, Wei SC, Cogdill AP, Zhao L, Hudgens CW, Hutchinson DS, Manzo T, Petaccia de Macedo M, Cotechini T, Kumar T, Chen WS, Reddy SM, Sloane RS, Galloway-Pena J, Jiang H, Chen PL, Shpall EJ, Rezvani K, Alousi AM, Chemaly RF, Shelburne S, Vence LM, Okhuysen PC, Jensen VB, Swennes AG, McAllister F, Sanchez EMR, Zhang Y, Le Chatelier E, Zitvogel L, Pons N, Austin-Breneman JL, Haydu LE, Burton EM, Gardner JM, Sirmans E, Hu J, Lazar AJ, Tsujikawa T, Diab A, Tawbi H, Glitza IC, Hwu WJ, Patel SP, Woodman SE, Amaria RN, Davies MA, Gershenwald JE, Hwu P, Lee JE, Zhang J, Coussens LM, Cooper ZA, Futreal PA, Daniel CR, Ajami NJ, Petrosino JF, Tetzlaff MT, Sharma P, Allison JP, Jenq RR, Wargo JA

Science.. 2018 January 5359 (6371):97-103. Epub 11/02/2017.

A phase II study of combined therapy with a BRAF inhibitor (vemurafenib) and interleukin-2 (aldesleukin) in patients with metastatic melanoma.

Mooradian MJ, Reuben A, Prieto PA, Hazar-Rethinam M, Frederick DT, Nadres B, Piris A, Juneja V, Cooper ZA, Sharpe AH, Corcoran RB, Flaherty KT, Lawrence DP, Wargo JA, Sullivan RJ

Oncoimmunology.. 2018 7 (5):e1423172. Epub 02/01/2018.

Integrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance.

Roh W, Chen PL, Reuben A, Spencer CN, Prieto PA, Miller JP, Gopalakrishnan V, Wang F, Cooper ZA, Reddy SM, Gumbs C, Little L, Chang Q, Chen WS, Wani K, De Macedo MP, Chen E, Austin-Breneman JL, Jiang H, Roszik J, Tetzlaff MT, Davies MA, Gershenwald JE, Tawbi H, Lazar AJ, Hwu P, Hwu WJ, Diab A, Glitza IC, Patel SP, Woodman SE, Amaria RN, Prieto VG, Hu J, Sharma P, Allison JP, Chin L, Zhang J, Wargo JA, Futreal PA

Science translational medicine.. 2017 March 19 (379)Epub 1900 01 01.

Gene Targeting Meets Cell-Based Therapy: Raising the Tail, or Merely a Whimper?

Cogdill AP, Prieto PA, Reuben A, Wargo JA

Clinical cancer research : an official journal of the American Association for Cancer Research.. 2017 January 1523 (2):327-329. Epub 11/11/2016.

Genomic and immune heterogeneity are associated with differential responses to therapy in melanoma.

Reuben A, Spencer CN, Prieto PA, Gopalakrishnan V, Reddy SM, Miller JP, Mao X, De Macedo MP, Chen J, Song X, Jiang H, Chen PL, Beird HC, Garber HR, Roh W, Wani K, Chen E, Haymaker C, Forget MA, Little LD, Gumbs C, Thornton RL, Hudgens CW, Chen WS, Austin-Breneman J, Sloane RS, Nezi L, Cogdill AP, Bernatchez C, Roszik J, Hwu P, Woodman SE, Chin L, Tawbi H, Davies MA, Gershenwald JE, Amaria RN, Glitza IC, Diab A, Patel SP, Hu J, Lee JE, Grimm EA, Tetzlaff MT, Lazar AJ, Wistuba II, Clise-Dwyer K, Carter BW, Zhang J, Futreal PA, Sharma P, Allison JP, Cooper ZA, Wargo JA

NPJ genomic medicine.. 2017 2 Epub 04/07/2017.

Cervical hematoma following an endocrine surgical procedure: The MD Anderson experience.

Christakis IA, Potylchansky E, Silva AM, Nates JP, Prieto PA, Graham PH, Grubbs EG, Lee JE, Perrier ND

Surgery.. 2016 August 160 (2):377-83. Epub 04/07/2016.

Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade.

Chen PL, Roh W, Reuben A, Cooper ZA, Spencer CN, Prieto PA, Miller JP, Bassett RL, Gopalakrishnan V, Wani K, De Macedo MP, Austin-Breneman JL, Jiang H, Chang Q, Reddy SM, Chen WS, Tetzlaff MT, Broaddus RJ, Davies MA, Gershenwald JE, Haydu L, Lazar AJ, Patel SP, Hwu P, Hwu WJ, Diab A, Glitza IC, Woodman SE, Vence LM, Wistuba II, Amaria RN, Kwong LN, Prieto V, Davis RE, Ma W, Overwijk WW, Sharpe AH, Hu J, Futreal PA, Blando J, Sharma P, Allison JP, Chin L, Wargo JA

Cancer discovery.. 2016 August 6 (8):827-37. Epub 06/14/2016.

Endocrine incidentalomas.

Starker LF, Prieto PA, Liles JS, Tran Cao HS, Grubbs EG, Lee JE, Perrier ND, Graham PH

Current problems in surgery.. 2016 May 53 (5):219-46. Epub 05/03/2016.

Distinct clinical patterns and immune infiltrates are observed at time of progression on targeted therapy versus immune checkpoint blockade for melanoma.

Cooper ZA, Reuben A, Spencer CN, Prieto PA, Austin-Breneman JL, Jiang H, Haymaker C, Gopalakrishnan V, Tetzlaff MT, Frederick DT, Sullivan RJ, Amaria RN, Patel SP, Hwu P, Woodman SE, Glitza IC, Diab A, Vence LM, Rodriguez-Canales J, Parra ER, Wistuba II, Coussens LM, Sharpe AH, Flaherty KT, Gershenwald JE, Chin L, Davies MA, Clise-Dwyer K, Allison JP, Sharma P, Wargo JA

Oncoimmunology.. 2016 March 5 (3):e1136044. Epub 02/02/2016.

Targeted Therapies Combined With Immune Checkpoint Therapy.

Prieto PA, Reuben A, Cooper ZA, Wargo JA

The cancer journal.. 2016 22 (2):138-46. Epub 1900 01 01.

Appendiceal endometriosis in a pregnant woman presenting with acute perforated appendicitis.

Lebastchi AH, Prieto PA, Chen C, Lui FY

Journal of surgical case reports.. 2013 December 162013 (12)Epub 12/16/2013.

DKK1 as a serum biomarker for hepatocellular carcinoma.

Prieto PA, Cha CH

Hepatobiliary surgery and nutrition.. 2013 June 2 (3):127-8. Epub 1900 01 01.

Tumor-specific CD4+ melanoma tumor-infiltrating lymphocytes.

Friedman KM, Prieto PA, Devillier LE, Gross CA, Yang JC, Wunderlich JR, Rosenberg SA, Dudley ME

Journal of immunotherapy.. 2012 June 35 (5):400-8. Epub 1900 01 01.

CTLA-4 blockade with ipilimumab: long-term follow-up of 177 patients with metastatic melanoma.

Prieto PA, Yang JC, Sherry RM, Hughes MS, Kammula US, White DE, Levy CL, Rosenberg SA, Phan GQ

Clinical cancer research : an official journal of the American Association for Cancer Research.. 2012 April 118 (7):2039-47. Epub 01/23/2012.

Liver directed therapy for renal cell carcinoma.

Langan RC, Ripley RT, Davis JL, Prieto PA, Datrice N, Steinberg SM, Bratslavsky G, Rudloff U, Kammula US, Stojadinovic A, Avital I

Journal of Cancer.. 2012 3 :184-90. Epub 04/20/2012.

Assessment of ovarian function after preparative chemotherapy and total body radiation for adoptive cell therapy.

Langan RC, Prieto PA, Sherry RM, Zlott D, Wunderlich J, Csako G, Costello R, White DE, Rosenberg SA, Yang JC

Journal of immunotherapy.. 2011 May 34 (4):397-402. Epub 1900 01 01.

CD8+ enriched "young" tumor infiltrating lymphocytes can mediate regression of metastatic melanoma.

Dudley ME, Gross CA, Langhan MM, Garcia MR, Sherry RM, Yang JC, Phan GQ, Kammula US, Hughes MS, Citrin DE, Restifo NP, Wunderlich JR, Prieto PA, Hong JJ, Langan RC, Zlott DA, Morton KE, White DE, Laurencot CM, Rosenberg SA

Clinical cancer research : an official journal of the American Association for Cancer Research.. 2010 December 1516 (24):6122-31. Epub 07/28/2010.

Enrichment of CD8+ cells from melanoma tumor-infiltrating lymphocyte cultures reveals tumor reactivity for use in adoptive cell therapy.

Prieto PA, Durflinger KH, Wunderlich JR, Rosenberg SA, Dudley ME

Journal of immunotherapy.. 2010 June 33 (5):547-56. Epub 1900 01 01.