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Welcome to the Prieto Laboratory

A native of New York, Dr. Peter A. Prieto chose to dedicate his life to conquering cancer after losing his father to sarcoma. Dr. Prieto, completed his general surgery residency at Yale University School of Medicine where he took three years off and completed a surgical oncology research fellowship and a one of its kind immunotherapy fellowship in the surgery branch of the National Cancer Institute, National Institutes of Health under the mentorship of Dr. Steven A. Rosenberg where he was co-investigator on numerous clinical trials. 

Dr. Prieto is triple board certified in complex general surgical oncology, general surgery and medical quality. As a fully trained tumor immunotherapist and surgical oncologist, he has expertise in the treatment of primary, regionally advanced and metastatic melanoma, soft tissue sarcoma and breast cancer. His research interests and laboratory investigate mechanisms of immune evasion by solid tumors to targeted and immune checkpoint blockade and prognostic markers of response to immune based therapies including adoptive cell therapy (including melanoma, sarcoma, cholangiocarcinoma and breast cancer). 

Peter A. Prieto, M.D., M.P.H.

Peter A. Prieto, M.D., M.P.H.
Principal Investigator

Research Projects

  • Genomic and immunologic profiling of tumor heterogeneity in metastatic melanoma to identify predictive biomarkers
  • Manipulation of the tumor microenvironment in cholangiocarcinoma for the delivery of translatable immunotherapies.
  • Optimization and characterization of mechanisms of resistance in solid tumor adoptive cell therapy
  • Characterization of the role of the host microbiome in response of immunotherapy in epithelial tumors



View All Publications


Contact Us

  Prieto Laboratory
601 Elmwood Ave
Rochester, NY 14642