Stephano Spano Mello, Ph.D.
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Stephano Spano Mello, Ph.D.
About Me
Faculty Appointments
Assistant Professor - Department of Biomedical Genetics (SMD)
Credentials
Post-doctoral Training & Residency
Postgraduate Research in Cancer Genetics, Stanford University, Stanford, CA 2009 - 2014
Postgraduate Research in Microbiology, University of Sao Paulo, Sao Paulo, Brazil 2007 - 2009
Education
PhD | Brazil-Fac Med Ribeirao Preto. Genetics. 2006
MSc | Brazil-Fac Med Ribeirao Preto. Genetics. 2002
BSc | Brazil - University of Sao Paulo. Biological Science. 1998
Awards
Early Investigator Advancement Program (EIAP) scholar. 2023
J. Martin Brown Award for Excellence in Radiation Sciences. 2017
Individual Grant (support for meeting attendance), nº 07/59639-0. 2008
Young Scientist prize. 2007
Environmental Mutagen Society (EMS) Travel Award, 9th International EMS Conference. 2005
Research
We utilize physiologically relevant in vivo models and a systems biology approach, integrating multiple types of genomic data to delineate important cellular events in tumor initiation. Our research provide insights on early detection of malignant lesions, and in the development of novel strategies to treat pancreatic cancer, pancreatitis and diabetes.
Publications
Journal Articles
DeRollo RE, Cazarin J, Ahmad Shahidan SNAB, Burchett JB, Mwangi D, Krishnaiah S, Hsieh AL, Walton ZE, Brooks R, Mello SS, Weljie AM, Dang CV, Altman BJ
bioRxiv : the preprint server for biology.. 2023 August 8 Epub 08/08/2023.
Cazarin J, DeRollo RE, Shahidan SNABA, Burchett JB, Mwangi D, Krishnaiah S, Hsieh AL, Walton ZE, Brooks R, Mello SS, Weljie AM, Dang CV, Altman BJ
PLoS genetics.. 2023 August 19 (8):e1010904. Epub 08/28/2023.
Liu X, Burke RM, Lighthouse JK, Baker CD, Dirkx RA, Kang B, Chakraborty Y, Mickelsen DM, Twardowski J, Mello SS, Ashton JM, Small EM
Circulation research.. 2023 July 21133 (3):271-287. Epub 07/06/2023.
Mello SS, Flowers BM, Mazur PK, Lee JJ, Müller F, Denny SK, Ferreira S, Hanson K, Kim SK, Greenleaf WJ, Wood LD, Attardi LD
Proceedings of the National Academy of Sciences of the United States of America.. 2023 March 7120 (10):e2211937120. Epub 02/27/2023.
Guo B, Friedland SC, Alexander W, Myers JA, Wang W, O'Dell MR, Getman M, Whitney-Miller CL, Agostini-Vulaj D, Huber AR, Mello SS, Vertino PM, Land HK, Steiner LA, Hezel AF
Cell reports.. 2022 August 3040 (9):111253. Epub 1900 01 01.
Moon EJ, Mello SS, Li CG, Chi JT, Thakkar K, Kirkland JG, Lagory EL, Lee IJ, Diep AN, Miao Y, Rafat M, Vilalta M, Castellini L, Krieg AJ, Graves EE, Attardi LD, Giaccia AJ
Nature communications.. 2021 July 1412 (1):4308. Epub 07/14/2021.
Bieging-Rolett KT, Kaiser AM, Morgens DW, Boutelle AM, Seoane JA, Van Nostrand EL, Zhu C, Houlihan SL, Mello SS, Yee BA, McClendon J, Pierce SE, Winters IP, Wang M, Connolly AJ, Lowe SW, Curtis C, Yeo GW, Winslow MM, Bassik MC, Attardi LD
Molecular cell.. 2020 November 580 (3):452-469.e9. Epub 1900 01 01.
Valente LJ, Tarangelo A, Li AM, Naciri M, Raj N, Boutelle AM, Li Y, Mello SS, Bieging-Rolett K, DeBerardinis RJ, Ye J, Dixon SJ, Attardi LD
The Journal of cell biology.. 2020 November 2219 (11)Epub 1900 01 01.
Huang J, Sachdeva M, Xu E, Robinson TJ, Luo L, Ma Y, Williams N, Lopez O, Cervia LD, Yuan F, Qin X, Zhang D, Owzar K, Gokgoz N, Seto A, Okada T, Singer S, Andrulis IL, Wunder J, Lazar AJ, Rubin BP, Pipho K, Mello SS, Giudice J, Kirsch DG
Molecular cancer research : MCR.. 2020 October 18 (10):1534-1544. Epub 06/19/2020.
Chernikova SB, Nguyen RB, Truong JT, Mello SS, Stafford JH, Hay MP, Olson A, Solow-Cordero DE, Wood DJ, Henry S, von Eyben R, Deng L, Gephart MH, Aroumougame A, Wiese C, Game JC, Gy?rffy B, Brown JM
The Journal of clinical investigation.. 2018 December 3128 (12):5307-5321. Epub 10/29/2018.
Mello SS, Attardi LD
Current opinion in cell biology.. 2018 April 51 :65-72. Epub 11/28/2017.
Mello SS, Attardi LD
Cell cycle.. 2018 17 (13):1527-1535. Epub 07/31/2018.
Mello SS, Valente LJ, Raj N, Seoane JA, Flowers BM, McClendon J, Bieging-Rolett KT, Lee J, Ivanochko D, Kozak MM, Chang DT, Longacre TA, Koong AC, Arrowsmith CH, Kim SK, Vogel H, Wood LD, Hruban RH, Curtis C, Attardi LD
Cancer cell.. 2017 October 932 (4):460-473.e6. Epub 1900 01 01.
Mello SS, Sinow C, Raj N, Mazur PK, Bieging-Rolett K, Broz DK, Imam JFC, Vogel H, Wood LD, Sage J, Hirose T, Nakagawa S, Rinn J, Attardi LD
Genes & development.. 2017 June 131 (11):1095-1108. Epub 07/11/2017.
Mazur PK, Herner A, Mello SS, Wirth M, Hausmann S, Sánchez-Rivera FJ, Lofgren SM, Kuschma T, Hahn SA, Vangala D, Trajkovic-Arsic M, Gupta A, Heid I, Noël PB, Braren R, Erkan M, Kleeff J, Sipos B, Sayles LC, Heikenwalder M, Heßmann E, Ellenrieder V, Esposito I, Jacks T, Bradner JE, Khatri P, Sweet-Cordero EA, Attardi LD, Schmid RM, Schneider G, Sage J, Siveke JT
Nature medicine.. 2015 October 21 (10):1163-71. Epub 09/21/2015.
Van Nostrand JL, Brisac A, Mello SS, Jacobs SB, Luong R, Attardi LD
Cancer discovery.. 2015 June 5 (6):622-35. Epub 03/26/2015.
Bieging KT, Mello SS, Attardi LD
Nature reviews. Cancer.. 2014 May 14 (5):359-70. Epub 04/17/2014.
Brady CA, Jiang D, Mello SS, Johnson TM, Jarvis LA, Kozak MM, Kenzelmann Broz D, Basak S, Park EJ, McLaughlin ME, Karnezis AN, Attardi LD
Cell.. 2011 May 13145 (4):571-83. Epub 1900 01 01.
Mello SS, Fachin AL, Junta CM, Sandrin-Garcia P, Donadi EA, Passos GA, Sakamoto-Hojo ET
Environmental and molecular mutagenesis.. 2011 March 52 (2):117-29. Epub 1900 01 01.
Gitaí DL, Fachin AL, Mello SS, Elias CF, Bittencourt JC, Leite JP, Passos GA, Garcia-Cairasco N, Paçó-Larson ML
Brain research.. 2011 January 71367 :114-21. Epub 10/23/2010.
Carminati PO, Mello SS, Fachin AL, Junta CM, Sandrin-Garcia P, Carlotti CG, Donadi EA, Passos GA, Sakamoto-Hojo ET
Genetics and molecular biology.. 2010 January 33 (1):159-68. Epub 03/01/2010.
Sandrin-Garcia P, Junta CM, Fachin AL, Mello SS, Baião AM, Rassi DM, Ferreira MC, Trevisan GL, Sakamoto-Hojo ET, Louzada-Júnior P, Passos GA, Donadi EA
Annals of the New York Academy of Sciences.. 2009 September 1173 :493-500. Epub 1900 01 01.
Junta CM, Sandrin-Garcia P, Fachin-Saltoratto AL, Mello SS, Oliveira RD, Rassi DM, Giuliatti S, Sakamoto-Hojo ET, Louzada-Junior P, Donadi EA, Passos GA
Immunology.. 2009 July 127 (3):365-72. Epub 12/17/2008.
Zárate-Bladés CR, Bonato VL, da Silveira EL, Oliveira e Paula M, Junta CM, Sandrin-Garcia P, Fachin AL, Mello SS, Cardoso RS, Galetti FC, Coelho-Castelo AA, Ramos SG, Donadi EA, Sakamoto-Hojo ET, Passos GA, Silva CL
The journal of gene medicine.. 2009 January 11 (1):66-78. Epub 1900 01 01.
Fachin AL, Mello SS, Sandrin-Garcia P, Junta CM, Ghilardi-Netto T, Donadi EA, Passos GA, Sakamoto-Hojo ET
Journal of radiation research.. 2009 January 50 (1):61-71. Epub 1900 01 01.
Rassi DM, Junta CM, Fachin AL, Sandrin-Garcia P, Mello S, Silva GL, Evangelista AF, Magalhães DA, Wastowski IJ, Crispim JO, Martelli-Palomino G, Fernandes AP, Deghaide NN, Foss-Freitas MC, Foss MC, Soares CP, Sakamoto-Hojo ET, Passos GA, Donadi EA
Annals of the New York Academy of Sciences.. 2008 December 1150 :282-9. Epub 1900 01 01.
Fachin AL, Mello SS, Sandrin-Garcia P, Junta CM, Donadi EA, Passos GA, Sakamoto-Hojo ET
Radiation research.. 2007 December 168 (6):650-65. Epub 1900 01 01.
Baião AM, Wowk PF, Sandrin-Garcia P, Junta CM, Fachin AL, Mello SS, Sakamoto-Hojo ET, Donadi EA, Passos GA
Molecular and cellular biochemistry.. 2007 October 304 (1-2):235-41. Epub 05/30/2007.
Silva GL, Junta CM, Mello SS, Garcia PS, Rassi DM, Sakamoto-Hojo ET, Donadi EA, Passos GA
Annals of the New York Academy of Sciences.. 2007 September 1110 :33-46. Epub 1900 01 01.
Rassi DM, Junta CM, Fachin AL, Sandrin-Garcia P, Mello SS, Fernandes AP, Deghaide NN, Foss-Freitas MC, Foss MC, Sakamoto-Hojo ET, Passos GA, Donadi EA
Annals of the New York Academy of Sciences.. 2006 October 1079 :305-9. Epub 1900 01 01.
Trevisan GL, Rassi DM, Baião AM, Sandrin-Garcia P, Mello SS, Tamia-Ferreira MC, Junta CM, Fachin AL, Marques MM, Sakamoto-Hojo ET, Donadi EA, Passos GA
Autoimmunity reviews.. 2006 May 5 (5):319-23. Epub 01/06/2006.
Cardoso RS, Junta CM, Macedo C, Magalhães DA, Silveira EL, Paula MO, Marques MM, Mello SS, Zárate-Bladés CR, Nguyen C, Houlgatte R, Donadi EA, Sakamoto-Hojo ET, Passos GA
Molecular immunology.. 2006 February 43 (5):464-72. Epub 04/13/2005.
Marques MM, Junta CM, Cardoso RS, Mello SS, Sakamoto-Hojo ET, Donadi EA, Passos GA
Molecular and cellular biochemistry.. 2005 August 276 (1-2):81-8. Epub 1900 01 01.
Magalhães DA, Macedo C, Junta CM, Mello SS, Marques MM, Cardoso RS, Sakamoto-Hojo ET, Donadi EA, Passos GA
Molecular immunology.. 2005 May 42 (9):1043-8. Epub 11/23/2004.
Pereira E, Tamia-Ferreira MC, Cardoso RS, Mello SS, Sakamoto-Hojo ET, Passos GA, Donadi EA
Immunology.. 2004 September 113 (1):99-105. Epub 1900 01 01.
Sakamoto-Hojo ET, Mello SS, Pereira E, Fachin AL, Cardoso RS, Junta CM, Sandrin-Garcia P, Donadi EA, Passos GA
Mutation research.. 2003 November 544 (2-3):403-13. Epub 1900 01 01.
Peitl P, Mello SS, Camparoto ML, Passos GA, Hande MP, Cardoso RS, Sakamoto-Hojo ET
Mutagenesis.. 2002 January 17 (1):67-72. Epub 1900 01 01.