The amygdala is a central node in circuits processing affective stimuli that can elicit emotions. Although the amygdala is closely linked to emotional and mental health, it has been difficult to understand its precise role in certain operations and develop evidence-based interventions in humans because it is involved in multiple, overlapping functions.
These functions likely depend on extensive connections with cortical areas such as the anterior cingulate (ACC), ventromedial prefrontal (vmPFC; sometimes called subgenual ACC in the clinical literature), and orbitofrontal cortex (OFC).
I use the opportunity afforded by human neurosurgical procedures to record local field potentials (LFPs) and single-unit spiking activity from subcortical areas in human patients undergoing deep brain stimulation and intracranial recordings (iEEG). Clinically implanted electrodes are used to record data and casually manipulate amygdala and ACC circuits by delivering stimulation during behavioral performance.
Dr. Kaskan joined the faculty of Neurological Surgery in September 2020 after training in intraoperative neurophysiological monitoring for deep brain stimulation at the University of Louisville following his postdoctoral fellowship in the Laboratory of Neuropsychology at the National Institute of Mental Health. Dr Kaskan received a secondary appointment in Neuroscience at Albert Einstein College of Medicine in August 2023. He collaborates with research groups at the University of Iowa, University of Rochester, and Weill-Cornell Medicine.
Dr. Kaskan received his bachelor's degree from Clark University and went on to study at Cornell University and RIKEN Brain Science Institute in Tokyo, Japan. He earned his Ph.D. in Psychology (Neuroscience) from Vanderbilt University and completed his postdoctoral training at the National Institutes of Health, with partial support from a NARSAD Young Investigator Grant from the Brain and Behavior Foundation (2014).
Adjunct Assistant Professor - Department of Neuroscience (SMD)
Kaskan PM, Nicholas MA, Dean AM, Murray EA
The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2022 October 31 Epub 10/31/2022.
Kaskan PM, Dean AM, Nicholas MA, Mitz AR, Murray EA
NeuroImage.. 2019 January 1184 :932-942. Epub 10/03/2018.
Kaskan PM, Costa VD, Eaton HP, Zemskova JA, Mitz AR, Leopold DA, Ungerleider LG, Murray EA
Cerebral cortex.. 2017 May 127 (5):2739-2757. Epub 1900 01 01.
Baldwin MK, Kaskan PM, Zhang B, Chino YM, Kaas JH
The Journal of comparative neurology.. 2012 February 15520 (3):544-69. Epub 1900 01 01.
Kaskan PM, Dillenburger BC, Lu HD, Roe AW, Kaas JH
Frontiers in neuroanatomy.. 2010 4 :23. Epub 07/07/2010.
Kaskan PM, Lu HD, Dillenburger BC, Kaas JH, Roe AW
Cerebral cortex.. 2009 June 19 (6):1394-407. Epub 10/08/2008.
Kaskan PM, Lu HD, Dillenburger BC, Roe AW, Kaas JH
Frontiers in neuroscience.. 2007 October 151 (1):67-75. Epub 1900 01 01.
Kaskan PM, Kaas JH
The anatomical record : advances in integrative anatomy and evolutionary biology.. 2007 March 290 (3):349-66. Epub 1900 01 01.
Collins CE, Xu X, Khaytin I, Kaskan PM, Casagrande VA, Kaas JH
Proceedings of the National Academy of Sciences of the United States of America.. 2005 April 12102 (15):5594-9. Epub 04/04/2005.
Kaskan PM, Franco EC, Yamada ES, Silveira LC, Darlington RB, Finlay BL
Proceedings. Biological sciences. 2005 January 7272 (1558):91-100. Epub 1900 01 01.
Xu X, Collins CE, Kaskan PM, Khaytin I, Kaas JH, Casagrande VA
Proceedings of the National Academy of Sciences of the United States of America.. 2004 February 24101 (8):2566-71. Epub 1900 01 01.