Welcome to the Frederick J. and Marion A. Schindler Cognitive Neurophysiology Lab
The Cognitive Neurophysiology Lab at URMC (CNL-R) is a group of scientists, clinicians, and technicians based in the University of Rochester Medical Center Department of Neuroscience. We’re interested in understanding how the brain processes inputs from our sense organs. We have a particular interest in how conditions and disorders with genetic and neurological components affect sensory perception and sense-related cognition. To date, researchers in our lab have published articles related to Autism Spectrum Disorder, Dyslexia, Multiple Sclerosis, Neimann Pick Type C, addiction, ADHD, and Rett Syndrome, to name a few.
Current research projects include:
- Lysosomal Storage Disorders – Niemann-Pick and Batten Disease
- Rett Syndrome
- Dyslexia
- HIV and Addiction
- Autism
- Multisensory Integration & Learning
We utilize a variety of techniques including electroencephalography, electrocorticography, functional magnetic resonance imaging, and transgenic murine models to study the characteristics of these diseases and how they are manifested in the brain. Our mission is to identify and understand the physiology of the fundamental deficits behind these syndromes and to connect these deficiencies to common genetic, physiological, and behavioral traits. Furthering our knowledge of these diseases has allowed us to develop clinical trials to ameliorate these deficits and definitively measure that progress.
Current ProjectsLab Photos
John J. Foxe, Ph.D.
Principal Investigator
Edward G. Freedman, Ph.D.
Principal Investigator
- Social Determinants of Health and Pediatric Long COVID in the US.; JAMA pediatrics. 2026 Jan 05.
- Biomarkers.; Alzheimer's & dementia : the journal of the Alzheimer's Association; Vol 21 Suppl 2(Suppl 2), pp. e102933. 2025 Dec.
- Longitudinal Exploration of Auditory Sensory-Perceptual Processing in CLN3 Disease (Juvenile Neuronal Ceroid Lipofuscinosis (Batten disease)): A High-Density Auditory Evoked Potential (AEP) Study.; bioRxiv : the preprint server for biology. 2025 Nov 20.
- Processing of Emotional Faces Has Unique Functional and Cytoarchitectural Associations in those with an Autism Spectrum Diagnosis.; bioRxiv : the preprint server for biology. 2025 Nov 13.
News
Affiliations
- Neuroscience
- Imaging Sciences
- Neurology
- Psychiatry
- Center for Visual Science
- Cognitive Neurophysiology Lab @ Albert Einstein
- Del Monte Institute for Neuroscience
- Intellectual & Developmental Disabilities Research
- Schmitt Program on Integrative Neuroscience
- University of Rochester Center for Advanced Brain Imaging & Neurophysiology
- Biomedical Engineering Ph.D. Program
- Neurobiology & Anatomy Ph.D. Program
- Neuroscience Ph.D. Program
- Translational Biomedical Science Ph.D. Program
- Tivarus Lab
- UR CABIN
November 6, 2025
Sex and Age Shape Progression of Batten Disease, Brainwave Study Finds
August 15, 2025
Scientists Reveal How Senses Work Together in the Brain
April 14, 2025
What New Research Revels about Autism, Stimming, and Touch
December 9, 2024
Researchers ‘See’ Vulnerability to Gaming Addiction in the Adolescent Brain
Contact Us
Cognitive Neurophysiology Lab
601 Elmwood Ave,
Rochester, NY 14642
cogneurolabrochester@gmail.com
We’re located in the Medical Center Annex Building (RCBI Entrance) across from the entrance to the Medical School entrance.
Medical Center Annex 3rd floor - 3B.300