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John J. Foxe, Ph.D.

Contact Information

Phone Numbers

Office: (585) 275-1964

Research Labs

Faculty Appointments

Biography

Research

I am a translational researcher with a history of research studies on the basic neurophysiology of schizophrenia and autism. My work places special emphasis on the identification of endophenotypic markers in childhood neuropsychiatric diseases and in the linking of these biomarkers to the underlying genotype. Work in our lab has a consistent history of NIH and NSF funding, and a strong record of research productivity (160+ publications). Before joining the faculty at Einstein in January of 2010 (my alma mater), I served for 6 years as the Director of the PhD Program in Cognitive Neuroscience at The City College of New York. I was recruited to Einstein in January of 2010 as Director of Research for the Children's Evaluation and Rehabilitation Center (CERC), with a mandate to develop and coordinate clinical pediatric research across the college. Our lab employs an integrated multi-methodological approach to issues in the cognitive neurosciences, using structural and functional neuroimaging, high-density electrophysiology, imaging genomics, eye tracking, psychophysics and virtual reality to understand the neural basis of basic sensory-perceptual and cognitive functions. The work is translational at its core in that it employs an equal mix of basic-science projects in healthy individuals with clinical studies in patient populations. The approach taken is to first develop novel assays of a given perceptual or cognitive function in healthy individuals, which are then deployed in clinical populations of interest. The core mission of the lab is to understand the underlying neurobiology of developmental disorders, with a specific emphasis on Autism. The central goal is to develop more effective treatments and interventions through establishing basic knowledge and myself and my team have worked extensively in both adolescent Schizophrenia and Autism Spectrum Disorders. The lab also has a very extensive history of investigations into the neurophysiology of both basic and complex auditory processing, from investigations of the fundamental mechanisms of frequency representation all the way to high-level speech processing.

Publications

Journal Articles

1/11/2020
Francisco AA, Foxe JJ, Horsthuis DJ, Molholm S. "Impaired auditory sensory memory in Cystinosis despite typical sensory processing: A high-density electrical mapping study of the mismatch negativity (MMN)." NeuroImage. Clinical.. 2020 Jan 11; 25:102170. Epub 2020 Jan 11.

11/20/2019
Chye Y, Mackey S, Gutman BA, Ching CRK, Batalla A, Blaine S, Brooks S, Caparelli EC, Cousijn J, Dagher A, Foxe JJ, Goudriaan AE, Hester R, Hutchison K, Jahanshad N, Kaag AM, Korucuoglu O, Li CR, London ED, Lorenzetti V, Luijten M, Martin-Santos R, Meda SA, Momenan R, Morales A, Orr C, Paulus MP, Pearlson G, Reneman L, Schmaal L, Sinha R, Solowij N, Stein DJ, Stein EA, Tang D, Uhlmann A, van Holst R, Veltman DJ, Verdejo-Garcia A, Wiers RW, Yücel M, Thompson PM, Conrod P, Garavan H. "Subcortical surface morphometry in substance dependence: An ENIGMA addiction working group study." Addiction biology.. 2019 Nov 20; :e12830. Epub 2019 Nov 20.

9/27/2019
Mazurek KA, Richardson D, Abraham N, Foxe JJ, Freedman EG. "Utilizing high-density electroencephalography and motion capture technology to characterize sensorimotor integration while performing complex actions." IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society.. 2019 Sep 27; Epub 2019 Sep 27.

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