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John J. Foxe, Ph.D.

Contact Information

Phone Numbers

Office: (585) 275-1964

Research Labs

Faculty Appointments

Biography

Research

I am a translational researcher with a history of research studies on the basic neurophysiology of schizophrenia and autism. My work places special emphasis on the identification of endophenotypic markers in childhood neuropsychiatric diseases and in the linking of these biomarkers to the underlying genotype. Work in our lab has a consistent history of NIH and NSF funding, and a strong record of research productivity (160+ publications). Before joining the faculty at Einstein in January of 2010 (my alma mater), I served for 6 years as the Director of the PhD Program in Cognitive Neuroscience at The City College of New York. I was recruited to Einstein in January of 2010 as Director of Research for the Children's Evaluation and Rehabilitation Center (CERC), with a mandate to develop and coordinate clinical pediatric research across the college. Our lab employs an integrated multi-methodological approach to issues in the cognitive neurosciences, using structural and functional neuroimaging, high-density electrophysiology, imaging genomics, eye tracking, psychophysics and virtual reality to understand the neural basis of basic sensory-perceptual and cognitive functions. The work is translational at its core in that it employs an equal mix of basic-science projects in healthy individuals with clinical studies in patient populations. The approach taken is to first develop novel assays of a given perceptual or cognitive function in healthy individuals, which are then deployed in clinical populations of interest. The core mission of the lab is to understand the underlying neurobiology of developmental disorders, with a specific emphasis on Autism. The central goal is to develop more effective treatments and interventions through establishing basic knowledge and myself and my team have worked extensively in both adolescent Schizophrenia and Autism Spectrum Disorders. The lab also has a very extensive history of investigations into the neurophysiology of both basic and complex auditory processing, from investigations of the fundamental mechanisms of frequency representation all the way to high-level speech processing.

Publications

Journal Articles

9/3/2020
Knight EJ, Oakes L, Hyman SL, Freedman EG, Foxe JJ. "Individuals With Autism Have No Detectable Deficit in Neural Markers of Prediction Error When Presented With Auditory Rhythms of Varied Temporal Complexity." Autism research : official journal of the International Society for Autism Research.. 2020 Sep 3; Epub 2020 Sep 03.

7/17/2020
Francisco AA, Horsthuis DJ, Popiel M, Foxe JJ, Molholm S. "Atypical response inhibition and error processing in 22q11.2 Deletion Syndrome and schizophrenia: Towards neuromarkers of disease progression and risk." NeuroImage. Clinical.. 2020 Jul 17; 27:102351. Epub 2020 Jul 17.

6/10/2020
Sysoeva OV, Molholm S, Djukic A, Frey HP, Foxe JJ. "Atypical processing of tones and phonemes in Rett Syndrome as biomarkers of disease progression." Translational psychiatry.. 2020 Jun 10; 10(1):188. Epub 2020 Jun 10.

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