Welcome to the Frederick J. and Marion A. Schindler Cognitive Neurophysiology Lab

The Cognitive Neurophysiology Lab at URMC (CNL-R) is a group of scientists, clinicians, and technicians based in the University of Rochester Medical Center Department of Neuroscience. We’re interested in understanding how the brain processes inputs from our sense organs. We have a particular interest in how conditions and disorders with genetic and neurological components affect sensory perception and sense-related cognition. To date, researchers in our lab have published articles related to Autism Spectrum Disorder, Dyslexia, Multiple Sclerosis, Neimann Pick Type C, addiction, ADHD, and Rett Syndrome, to name a few.

Current research projects include:

• Lysosomal Storage Disorders – Niemann-Pick and Batten Disease
• Rett Syndrome
• Dyslexia
• HIV and Addiction
• Autism
• Multisensory Integration & Learning

We utilize a variety of techniques including electroencephalography, electrocorticography, functional magnetic resonance imaging, and transgenic murine models to study the characteristics of these diseases and how they are manifested in the brain. Our mission is to identify and understand the physiology of the fundamental deficits behind these syndromes and to connect these deficiencies to common genetic, physiological, and behavioral traits. Furthering our knowledge of these diseases has allowed us to develop clinical trials to ameliorate these deficits and definitively measure that progress.