CONTACT INFORMATIONCREDENTIALSPUBLICATIONSMark E. Dumont, Ph.D.Contact InformationPhone NumbersOffice: (585) 275-2466Fax: (585) 271-2683Research LabsVisit Lab WebsiteLocationsUniversity of Rochester Medical CenterSchool of Medicine and Dentistry601 Elmwood Ave, Box 712Rochester, NY 14642Faculty AppointmentsProfessor - Department of Biochemistry and Biophysics (SMD) BiographyResearchTransmembrane proteins carry out critical functions in transporting ions and metabolites in an out of cells and organelles, in transducing extracellular signals into intracellular responses, in cell-cell recognition, and in catalyzing a variety of enzymatic reactions. They also constitute 20-30% of the protein coding potential of most genomes. However, the structures and molecular mechanisms of the function of membrane proteins remain much more poorly characterized than is the case for most soluble proteins. The Dumont laboratory focuses on understanding mechanisms of membrane protein function at the molecular level.CredentialsEducation1972BA | Harvard UniversityPhysics1975MS | Western Washington State CollPhysics1980PhD | Johns Hopkins UniversityBiophysicsPublicationsJournal Articles2019Zhu H, Mathew E, Connelly SM, Zuber J, Sullivan M, Piepenbrink MS, Kobie JJ, Dumont ME. "Identification of variant HIV envelope proteins with enhanced affinities for precursors to anti-gp41 broadly neutralizing antibodies." PloS one.. 2019 14(9):e0221550. Epub 2019 Sep 10. 2018Mathew E, Zhu H, Connelly SM, Sullivan MA, Brewer MG, Piepenbrink MS, Kobie JJ, Dewhurst S, Dumont ME. "Display of the HIV envelope protein at the yeast cell surface for immunogen development." PloS one.. 2018 13(10):e0205756. Epub 2018 Oct 18. 2/2017Clark KM, Jenkins JL, Fedoriw N, Dumont ME. "Human CaaX protease ZMPSTE24 expressed in yeast: Structure and inhibition by HIV protease inhibitors." Protein science : a publication of the Protein Society.. 2017 Feb 0; 26(2):242-257. Epub 2016 Nov 11. VIEW ALL PUBLICATIONSClose WindowSchedule an appointment with Mark E. Dumont, Ph.D.Please answer the following questions to help us find the right appointment for you.Important: If you believe that you have a medical or psychiatric emergency, please call 911 or go to the nearest hospital. This website is not intended for emergency care.Have you seen this provider in the last 2 years?YesNoExisting Patient Schedule or request a follow up appointment online through MyChart. If you do not have a MyChart account, please close this window and call the appointment phone number. Mark E. Dumont, Ph.D. is currently scheduling for the following appointment type(s): Our policy does not permit patients to establish care with multiple providers within the same practice or specialty without prior approval. If you choose a new provider in the same office, we will cancel the appointment. Please contact the office directly with questions on this policy.