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Scott A. Gerber, Ph.D.


Showing all 49 journal articles & 0 books available

Journal Articles

Qin SS, Han BJ, Williams A, Jackson KM, Jewell R, Chacon AC, Lord EM, Linehan DC, Kim M, Reuben A, Gerber SA, Prieto PA. "Intertumoral Genetic Heterogeneity Generates Distinct Tumor Microenvironments in a Novel Murine Synchronous Melanoma Model." Cancers.. 2021 May 11; 13(10)Epub 2021 May 11.

Cole CL, Bachman JF, Ye J, Murphy J, Gerber SA, Beck CA, Boyce BF, Muthukrishnan G, Chakkalakal JV, Schwarz EM, Linehan D. "Increased myocellular lipid and IGFBP-3 expression in a pre-clinical model of pancreatic cancer-related skeletal muscle wasting." Journal of cachexia, sarcopenia and muscle.. 2021 May 7; Epub 2021 May 07.

Battaglia NG, Uccello TP, Hughson A, Garrett-Larsen J, Caldon JJ, Qiu H, Gerber SA, Lord EM. "Co-administration of a clinically relevant dexamethasone dosage with ablative radiotherapy reduces peripheral lymphocytes but does not alter in vivo intratumoral lymphocyte phenotype or inhibit efficacy of radiotherapy in a murine colorectal tumor model." International journal of radiation oncology, biology, physics.. 2021 Apr 29; Epub 2021 Apr 29.

Baek J, Ahmed R, Ye J, Gerber SA, Parker KJ, Doyley MM. "H-scan, Shear Wave and Bioluminescent Assessment of the Progression of Pancreatic Cancer Metastases in the Liver." Ultrasound in medicine & biology.. 2020 Sep 6; Epub 2020 Sep 06.

Rha B, Lively JY, Englund JA, Staat MA, Weinberg GA, Selvarangan R, Halasa NB, Williams JV, Boom JA, Sahni LC, Michaels MG, Stewart LS, Harrison CJ, Szilagyi PG, McNeal MM, Klein EJ, Strelitz B, Lacombe K, Schlaudecker E, Moffatt ME, Schuster JE, Pahud BA, Weddle G, Hickey RW, Avadhanula V, Wikswo ME, Hall AJ, Curns AT, Gerber SI, Langley G. "SARS-CoV-2 Infections in Children - Multi-Center Surveillance, United States, January-March 2020." Journal of the Pediatric Infectious Diseases Society.. 2020 Jun 18; Epub 2020 Jun 18.

Rha B, Curns AT, Lively JY, Campbell AP, Englund JA, Boom JA, Azimi PH, Weinberg GA, Staat MA, Selvarangan R, Halasa NB, McNeal MM, Klein EJ, Harrison CJ, Williams JV, Szilagyi PG, Singer MN, Sahni LC, Figueroa-Downing D, McDaniel D, Prill MM, Whitaker BL, Stewart LS, Schuster JE, Pahud BA, Weddle G, Avadhanula V, Munoz FM, Piedra PA, Payne DC, Langley G, Gerber SI. "Respiratory Syncytial Virus-Associated Hospitalizations Among Young Children: 2015-2016." Pediatrics.. 2020 Jun 16; Epub 2020 Jun 16.

Han BJ, Murphy JD, Qin S, Ye J, Uccello TP, Garrett-Larsen J, Belt BA, Prieto PA, Egilmez NK, Lord EM, Linehan DC, Mills BN, Gerber SA. "Microspheres Encapsulating Immunotherapy Agents Target the Tumor-Draining Lymph Node in Pancreatic Ductal Adenocarcinoma." Immunological investigations.. 2020 Jun 4; :1-16. Epub 2020 Jun 04.

Wang H, Mills B, Mislati R, Ahmed R, Gerber SA, Linehan D, Doyley MM. "Shear Wave Elastography Can Differentiate between Radiation-Responsive and Non-responsive Pancreatic Tumors: An ex Vivo Study with Murine Models." Ultrasound in medicine & biology.. 2020 Feb 0; 46(2):393-404. Epub 2019 Nov 11.

Cole CL, Beck CA, Robinson D, Ye J, Mills B, Gerber SA, Schwarz EM, Linehan D. "Dual Energy X-ray Absorptiometry (DEXA) as a longitudinal outcome measure of cancer-related muscle wasting in mice." PloS one.. 2020 15(6):e0230695. Epub 2020 Jun 19.

Ye J, Mills BN, Zhao T, Han BJ, Murphy JD, Patel AP, Johnston CJ, Lord EM, Belt BA, Linehan DC, Gerber SA. "Assessing the Magnitude of Immunogenic Cell Death Following Chemotherapy and Irradiation Reveals a New Strategy to Treat Pancreatic Cancer." Cancer immunology research.. 2019 Nov 12; Epub 2019 Nov 12.

Mills BN, Connolly KA, Ye J, Murphy JD, Uccello TP, Han BJ, Zhao T, Drage MG, Murthy A, Qiu H, Patel A, Figueroa NM, Johnston CJ, Prieto PA, Egilmez NK, Belt BA, Lord EM, Linehan DC, Gerber SA. "Stereotactic Body Radiation and Interleukin-12 Combination Therapy Eradicates Pancreatic Tumors by Repolarizing the Immune Microenvironment." Cell reports.. 2019 Oct 8; 29(2):406-421.e5.

Murthy A, Gerber SA, Koch CJ, Lord EM. "Intratumoral Hypoxia Reduces IFN-?-Mediated Immunity and MHC Class I Induction in a Preclinical Tumor Model." . 2019 Apr 29; 3(4):149-160. Epub 2019 Apr 29.

MacDonald CR, Bucsek MJ, Qiao G, Chen M, Evans L, Greenberg DJ, Uccello TP, Battaglia NG, Hylander BL, Singh AK, Lord EM, Gerber SA, Repasky EA. "Adrenergic Receptor Signaling Regulates the Response of Tumors to Ionizing Radiation." Radiation research.. 2019 Apr 25; Epub 2019 Apr 25.

Ahmed R, Gerber SA, McAleavey SA, Schifitto G, Doyley MM. "Plane-Wave Imaging Improves Single-Track Location Shear Wave Elasticity Imaging." IEEE transactions on ultrasonics, ferroelectrics, and frequency control.. 2018 Aug 0; 65(8):1402-1414. Epub 2018 Jun 01.

Meyers JL, Winans B, Kelsaw E, Murthy A, Gerber S, Lawrence BP. "Environmental cues received during development shape dendritic cell responses later in life." PloS one.. 2018 13(11):e0207007. Epub 2018 Nov 09.

Connolly KA, Belt BA, Figueroa NM, Murthy A, Patel A, Kim M, Lord EM, Linehan DC, Gerber SA. "Increasing the efficacy of radiotherapy by modulating the CCR2/CCR5 chemokine axes." Oncotarget.. 2016 Dec 27; 7(52):86522-86535.

Barlow ML, Cummings RJ, Pentland AP, Love TM, Haidaris CG, Ryan JL, Lord EM, Gerber SA. "Total-Body Irradiation Exacerbates Dissemination of Cutaneous Candida Albicans Infection." Radiation research.. 2016 Nov 0; 186(5):436-446. Epub 2016 Oct 06.

Lambert Emo K, Hyun YM, Reilly E, Barilla C, Gerber S, Fowell D, Kim M, Topham DJ. "Live Imaging of Influenza Infection of the Trachea Reveals Dynamic Regulation of CD8+ T Cell Motility by Antigen." PLoS pathogens.. 2016 Sep 0; 12(9):e1005881. Epub 2016 Sep 19.

Zozzaro-Smith PE, Bushway ME, Gerber SA, Hebert D, Pressman EK, Lord EM, Miller RK, Murphy SP. "Whole mount immunofluorescence analysis of placentas from normotensive versus preeclamptic pregnancies." Placenta.. 2015 Nov 0; 36(11):1310-7. Epub 2015 Sep 10.

Gerber SA, Cummings RJ, Judge JL, Barlow ML, Nanduri J, Johnson DE, Palis J, Pentland AP, Lord EM, Ryan JL. "Interleukin-12 preserves the cutaneous physical and immunological barrier after radiation exposure." Radiation research.. 2015 Jan 0; 183(1):72-81. Epub 2015 Jan 07.

Gerber SA, Lim JY, Connolly KA, Sedlacek AL, Barlow ML, Murphy SP, Egilmez NK, Lord EM. "Radio-responsive tumors exhibit greater intratumoral immune activity than nonresponsive tumors." International journal of cancer.. 2014 May 15; 134(10):2383-92. Epub 2013 Nov 11.

Bushway ME, Gerber SA, Fenton BM, Miller RK, Lord EM, Murphy SP. "Morphological and phenotypic analyses of the human placenta using whole mount immunofluorescence." Biology of reproduction.. 2014 May 0; 90(5):110. Epub 2014 Mar 19.

Xu Y, Hyun YM, Lim K, Lee H, Cummings RJ, Gerber SA, Bae S, Cho TY, Lord EM, Kim M. "Optogenetic control of chemokine receptor signal and T-cell migration." Proceedings of the National Academy of Sciences of the United States of America.. 2014 Apr 29; 111(17):6371-6. Epub 2014 Apr 14.

Lim JY, Gerber SA, Murphy SP, Lord EM. "Type I interferons induced by radiation therapy mediate recruitment and effector function of CD8(+) T cells." Cancer immunology, immunotherapy : CII.. 2014 Mar 0; 63(3):259-71. Epub 2013 Dec 20.

Majumder S, Sowden MP, Gerber SA, Thomas T, Christie CK, Mohan A, Yin G, Lord EM, Berk BC, Pang J. "G-protein-coupled receptor-2-interacting protein-1 is required for endothelial cell directional migration and tumor angiogenesis via cortactin-dependent lamellipodia formation." Arteriosclerosis, thrombosis, and vascular biology.. 2014 Feb 0; 34(2):419-26. Epub 2013 Nov 21.

Hofmann AP, Gerber SA, Croy BA. "Uterine natural killer cells pace early development of mouse decidua basalis." Molecular human reproduction.. 2014 Jan 0; 20(1):66-76. Epub 2013 Sep 01.

Lim JY, Brockstedt DG, Lord EM, Gerber SA. "Radiation therapy combined with -based cancer vaccine synergize to enhance tumor control in the B16 melanoma model." Oncoimmunology.. 2014 3:e29028. Epub 2014 Jun 03.

Sedlacek AL, Gerber SA, Randall TD, van Rooijen N, Frelinger JG, Lord EM. "Generation of a dual-functioning antitumor immune response in the peritoneal cavity." The American journal of pathology.. 2013 Oct 0; 183(4):1318-1328. Epub 2013 Aug 08.

Lu N, Silva J, Gu Y, Gerber S, Wu H, Gelbard H, Dewhurst S, Miao H. "Directional Histogram Ratio at Random Probes: A Local Thresholding Criterion for Capillary Images." Pattern recognition. 2013 Jul 1; 46(7):1933-1948. Epub 2013 Jan 18.

Gerber SA, Sedlacek AL, Cron KR, Murphy SP, Frelinger JG, Lord EM. "IFN-? mediates the antitumor effects of radiation therapy in a murine colon tumor." The American journal of pathology.. 2013 Jun 0; 182(6):2345-54. Epub 2013 Apr 12.

Gerber SA, Sorensen EW, Sedlacek AL, Lim JY, Skrombolas D, Frelinger JG, Lord EM. "Local expression of interleukin-2 by B16 melanoma cells results in decreased tumour growth and long-term tumour dormancy." Immunology.. 2013 Mar 0; 138(3):280-92.

Yokota SJ, Facciponte JG, Kelleher RJ, Shultz LD, Loyall JL, Parsons RR, Odunsi K, Frelinger JG, Lord EM, Gerber SA, Balu-Iyer SV, Bankert RB. "Changes in ovarian tumor cell number, tumor vasculature, and T cell function monitored in vivo using a novel xenograft model." Cancer immunity. 2013 13:11. Epub 2013 May 31.

Cummings RJ, Gerber SA, Judge JL, Ryan JL, Pentland AP, Lord EM. "Exposure to ionizing radiation induces the migration of cutaneous dendritic cells by a CCR7-dependent mechanism." The Journal of immunology : official journal of the American Association of Immunologists.. 2012 Nov 1; 189(9):4247-57. Epub 2012 Sep 21.

Croy BA, Chen Z, Hofmann AP, Lord EM, Sedlacek AL, Gerber SA. "Imaging of vascular development in early mouse decidua and its association with leukocytes and trophoblasts." Biology of reproduction.. 2012 Nov 0; 87(5):125. Epub 2012 Nov 29.

Hatta K, MacLeod RJ, Gerber SA, Croy BA. "Emerging themes in uterine natural killer cell heterogeneity and function." American journal of reproductive immunology : AJRI.. 2012 Oct 0; 68(4):282-9. Epub 2012 May 24.

Harding MJ, Lepus CM, Gibson TF, Shepherd BR, Gerber SA, Graham M, Paturzo FX, Rahner C, Madri JA, Bothwell AL, Lindenbach BD, Pober JS. "An implantable vascularized protein gel construct that supports human fetal hepatoblast survival and infection by hepatitis C virus in mice." PloS one.. 2010 Apr 1; 5(4):e9987. Epub 2010 Apr 01.

Sorensen EW, Gerber SA, Frelinger JG, Lord EM. "IL-12 suppresses vascular endothelial growth factor receptor 3 expression on tumor vessels by two distinct IFN-gamma-dependent mechanisms." The Journal of immunology : official journal of the American Association of Immunologists.. 2010 Feb 15; 184(4):1858-66. Epub 2010 Jan 08.

Sorensen EW, Gerber SA, Sedlacek AL, Rybalko VY, Chan WM, Lord EM. "Omental immune aggregates and tumor metastasis within the peritoneal cavity." Immunologic research.. 2009 Dec 0; 45(2-3):185-94. Epub 2009 Feb 28.

Lepus CM, Gibson TF, Gerber SA, Kawikova I, Szczepanik M, Hossain J, Ablamunits V, Kirkiles-Smith N, Herold KC, Donis RO, Bothwell AL, Pober JS, Harding MJ. "Comparison of human fetal liver, umbilical cord blood, and adult blood hematopoietic stem cell engraftment in NOD-scid/gammac-/-, Balb/c-Rag1-/-gammac-/-, and C.B-17-scid/bg immunodeficient mice." Human immunology.. 2009 Oct 0; 70(10):790-802. Epub 2009 Jun 12.

Gerber SA, Yatsula B, Maier CL, Sadler TJ, Whittaker LW, Pober JS. "Interferon-gamma induces prolyl hydroxylase (PHD)3 through a STAT1-dependent mechanism in human endothelial cells." Arteriosclerosis, thrombosis, and vascular biology.. 2009 Sep 0; 29(9):1363-9. Epub 2009 Jul 02.

Suárez Y, Fernández-Hernando C, Yu J, Gerber SA, Harrison KD, Pober JS, Iruela-Arispe ML, Merkenschlager M, Sessa WC. "Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis." Proceedings of the National Academy of Sciences of the United States of America.. 2008 Sep 16; 105(37):14082-7. Epub 2008 Sep 08.

Gerber SA, Pober JS. "IFN-alpha induces transcription of hypoxia-inducible factor-1alpha to inhibit proliferation of human endothelial cells." The Journal of immunology : official journal of the American Association of Immunologists.. 2008 Jul 15; 181(2):1052-62.

Lugade AA, Sorensen EW, Gerber SA, Moran JP, Frelinger JG, Lord EM. "Radiation-induced IFN-gamma production within the tumor microenvironment influences antitumor immunity." The Journal of immunology : official journal of the American Association of Immunologists.. 2008 Mar 1; 180(5):3132-9.

Gerber SA, Rybalko VY, Bigelow CE, Lugade AA, Foster TH, Frelinger JG, Lord EM. "Preferential attachment of peritoneal tumor metastases to omental immune aggregates and possible role of a unique vascular microenvironment in metastatic survival and growth." The American journal of pathology.. 2006 Nov 0; 169(5):1739-52.

Lugade AA, Moran JP, Gerber SA, Rose RC, Frelinger JG, Lord EM. "Local radiation therapy of B16 melanoma tumors increases the generation of tumor antigen-specific effector cells that traffic to the tumor." The Journal of immunology : official journal of the American Association of Immunologists.. 2005 Jun 15; 174(12):7516-23.

Gerber SA, Turner MJ, Lugade AA, Moran JP, Frelinger JG, Lord EM. "Characterization of a lymph node within the mouse prostate: Detailed analysis using whole mount histology." The Prostate.. 2005 May 1; 63(2):105-16.

Moran JP, Gerber SA, Martin CA, Frelinger JG, Lord EM. "Transfection of the genes for interleukin-12 into the K1735 melanoma and the EMT6 mammary sarcoma murine cell lines reveals distinct mechanisms of antitumor activity." International journal of cancer.. 2003 Sep 20; 106(5):690-8.

Gerber SA, Moran JP, Frelinger JG, Frelinger JA, Fenton BM, Lord EM. "Mechanism of IL-12 mediated alterations in tumour blood vessel morphology: analysis using whole-tissue mounts." British journal of cancer.. 2003 May 6; 88(9):1453-61.

Gerber S, Lane C, Brown DM, Lord E, DiLorenzo M, Clements JD, Rybicki E, Williamson AL, Rose RC. "Human papillomavirus virus-like particles are efficient oral immunogens when coadministered with Escherichia coli heat-labile enterotoxin mutant R192G or CpG DNA." Journal of virology.. 2001 May 0; 75(10):4752-60.