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Scott A. Gerber, Ph.D.

Scott A. Gerber, Ph.D.

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About Me

Faculty Appointments

Associate Professor - Department of Surgery, Research (SMD)

Associate Professor - Cancer Center - Joint

Associate Professor - Department of Microbiology and Immunology (SMD) - Joint

Associate Professor - Department of Radiation Oncology (SMD) - Joint

Credentials

Post-doctoral Training & Residency

Yale University, New Haven, CT (Mentor: Jordan Pober) 2005 - 2008

Education

PhD | University of Rochester School of Medicine & Dentistry. Microbiology & Immunology. 2005

MS | University of Rochester School of Medicine & Dentistry. Immunology. 2001

BS | SUNY Coll at Fredonia. Biology. 1997

Awards

National Cancer Institute R01 CA230277. 2019

URMC Outstanding Graduate Student Teacher Award. 2019

University Research Award. 2018 - 2019

Clinical and Translational Science Institute Pilot Study Award. 2018

Wilmot Cancer Institute Collaborative Award. 2017

Washington University SPORE in Pancreatic Cancer Developmental Research Award. 2016

UR/UB Genomics Collaborative Pilot Award. 2016

American Association of Immunologist (AAI) Early Career Faculty Travel Grant. 2012 - 2013

Anna Fuller Fund Fellowship in Molecular Oncology. 2008

Vincent du Vigneaud Award for outstanding doctoral thesis. 2006

Research

Dr. Gerber is a tumor immunologist whose laboratory focuses on harnessing the immune system to recognize and kill cancerous cells. His lab uses an immunotherapeutic approach to enhance the efficacy of chemo/radiotherapies to control or even cure both primary and metastatic malignancies.

Publications

Journal Articles

High-Density Polyethylene Custom Focusing Lenses for High-Resolution Transient Terahertz Biomedical Imaging Sensors.

Chakraborty D, Boni R, Mills BN, Cheng J, Komissarov I, Gerber SA, Sobolewski R

Sensors.. 2024 March 2424 (7)Epub 03/24/2024.

Respiratory Syncytial Virus-Associated Hospitalizations Among Children <5 Years Old: 2016 to 2020.

Curns AT, Rha B, Lively JY, Sahni LC, Englund JA, Weinberg GA, Halasa NB, Staat MA, Selvarangan R, Michaels M, Moline H, Zhou Y, Perez A, Rohlfs C, Hickey R, Lacombe K, McHenry R, Whitaker B, Schuster J, Pulido CG, Strelitz B, Quigley C, Dnp GW, Avadhanula V, Harrison CJ, Stewart LS, Schlaudecker E, Szilagyi PG, Klein EJ, Boom J, Williams JV, Langley G, Gerber SI, Hall AJ, McMorrow ML

Pediatrics.. 2024 February 1 Epub 02/01/2024.

Effects of mammary cancer and chemotherapy on neuroimmunological markers and memory function in a preclinical mouse model.

Netherby-Winslow C, Thompson B, Lotta L, Gallagher M, Van Haute P, Yang R, Hott D, Hasan H, Bachmann K, Bautista J, Gerber S, Cory-Slechta DA, Janelsins M

Brain, behavior, & immunity - health.. 2023 December 34 :100699. Epub 11/07/2023.

Shear wave elastography can stratify rectal cancer response to short-course radiation therapy.

Mislati R, Uccello TP, Lin Z, Iliza KT, Toussaint KC, Gerber SA, Doyley MM

Scientific reports.. 2023 September 2613 (1):16149. Epub 09/26/2023.

New insights into the responder/nonresponder divide in rectal cancer: Damage-induced Type I IFNs dictate treatment efficacy and can be targeted to enhance radiotherapy.

Uccello TP, Lesch ML, Kintzel SA, Gradzewicz LB, Lamrous L, Murphy SP, Fleming FJ, Mills BN, Murphy JD, Hughson A, Hannon G, Garrett-Larsen J, Qiu H, Drage MG, Ye J, Gavras NW, Keeley DC, Love TMT, Repasky EA, Lord EM, Linehan DC, Gerber SA

Cell death & disease.. 2023 July 2614 (7):470. Epub 07/26/2023.

Vitamin D Receptor Antagonist MeTC7 Inhibits PD-L1.

Khazan N, Quarato ER, Singh NA, Snyder CWA, Moore T, Miller JP, Yasui M, Teramoto Y, Goto T, Reshi S, Hong J, Zhang N, Pandey D, Srivastava P, Morell A, Kawano H, Kawano Y, Conley T, Sahasrabudhe DM, Yano N, Miyamoto H, Aljitawi O, Liesveld J, Becker MW, Calvi LM, Zhovmer AS, Tabdanov ED, Dokholyan NV, Linehan DC, Hansen JN, Gerber SA, Sharon A, Khera MK, Jurutka PW, Rochel N, Kim KK, Rowswell-Turner RB, Singh RK, Moore RG

Cancers.. 2023 June 3015 (13)Epub 06/30/2023.

CD73 and PD-L1 dual blockade amplifies antitumor efficacy of SBRT in murine PDAC models.

Ye J, Gavras NW, Keeley DC, Hughson AL, Hannon G, Vrooman TG, Lesch ML, Johnston CJ, Lord EM, Belt BA, Linehan DC, Eyles J, Gerber SA

Journal for immunotherapy of cancer.. 2023 May 11 (5)Epub 1900 01 01.

ST3GAL1 and ?II-spectrin pathways control CAR T cell migration to target tumors.

Hong Y, Walling BL, Kim HR, Serratelli WS, Lozada JR, Sailer CJ, Amitrano AM, Lim K, Mongre RK, Kim KD, Capece T, Lomakina EB, Reilly NS, Vo K, Gerber SA, Fan TC, Yu AL, Oakes PW, Waugh RE, Jun CD, Reagan PM, Kim M

Nature immunology.. 2023 April 17 Epub 04/17/2023.

Harnessing the Immunological Effects of Radiation to Improve Immunotherapies in Cancer.

Hannon G, Lesch ML, Gerber SA

International journal of molecular sciences.. 2023 April 1624 (8)Epub 04/16/2023.

New insights into the responder/nonresponder divide in rectal cancer: Damage-induced Type I IFNs dictate treatment efficacy and can be targeted to enhance radiotherapy.

Gerber S, Uccello T, Lesch M, Kintzel S, Gradzewicz L, Lamrous L, Murphy S, Fleming F, Mills B, Murphy J, Hughson A, Garrett-Larsen J, Qiu H, Drage M, Ye J, Gavras N, Keeley D, Love T, Repasky E, Lord E, Linehan D

Research square.. 2023 April 13 Epub 04/13/2023.

Development of Terahertz Imaging Markers for Pancreatic Ductal Adenocarcinoma using Maximum Probability (MAP) Estimation.

Chakraborty D, Mills BN, Cheng J, Komissarov I, Gerber SA, Sobolewski R

ACS omega.. 2023 March 218 (11):9925-9933. Epub 03/08/2023.

Circulation of Rhinoviruses and/or Enteroviruses in Pediatric Patients With Acute Respiratory Illness Before and During the COVID-19 Pandemic in the US.

Rankin DA, Spieker AJ, Perez A, Stahl AL, Rahman HK, Stewart LS, Schuster JE, Lively JY, Haddadin Z, Probst V, Michaels MG, Williams JV, Boom JA, Sahni LC, Staat MA, Schlaudecker EP, McNeal MM, Harrison CJ, Weinberg GA, Szilagyi PG, Englund JA, Klein EJ, Gerber SI, McMorrow M, Rha B, Chappell JD, Selvarangan R, Midgley CM, Halasa NB,

JAMA network open.. 2023 February 16 (2):e2254909. Epub 02/01/2023.

PD-1 CAR-T cells provide superior protection against solid tumors.

Sailer CJ, Hong Y, Dahal A, Ryan AT, Mir S, Gerber SA, Reagan PM, Kim M

Frontiers in immunology.. 2023 14 :1187850. Epub 06/14/2023.

Respiratory Virus Surveillance Among Children with Acute Respiratory Illnesses - New Vaccine Surveillance Network, United States, 2016-2021.

Perez A, Lively JY, Curns A, Weinberg GA, Halasa NB, Staat MA, Szilagyi PG, Stewart LS, McNeal MM, Clopper B, Zhou Y, Whitaker BL, LeMasters E, Harker E, Englund JA, Klein EJ, Selvarangan R, Harrison CJ, Boom JA, Sahni LC, Michaels MG, Williams JV, Langley GE, Gerber SI, Campbell A, Hall AJ, Rha B, McMorrow M,

MMWR. Morbidity and mortality weekly report.. 2022 October 771 (40):1253-1259. Epub 10/07/2022.

Radiotherapy exacerbates tumor-promoting innervation and nerve signaling in rectal cancer.

Uccello TP, Lecsh ML, Ullman NA, Kintzel SA, Gradzewicz LB, Velagaleti T, Fleming FJ, Mills BN, Murphy JD, Garrett-Larsen J, Qiu H, Drage MG, Ye J, Gavras NW, Johnston CJ, Love TMT, Repasky EA, Linehan DC, Lord EM, Gerber SA

International journal of radiation oncology, biology, physics.. 2022 October 3 Epub 10/03/2022.

Clinical Presentation and Severity of Adenovirus Detection Alone vs Adenovirus Co-detection With Other Respiratory Viruses in US Children With Acute Respiratory Illness from 2016 to 2018.

Probst V, Spieker AJ, Stopczynski T, Stewart LS, Haddadin Z, Selvarangan R, Harrison CJ, Schuster JE, Staat MA, McNeal M, Weinberg GA, Szilagyi PG, Boom JA, Sahni LC, Piedra PA, Englund JA, Klein EJ, Michaels MG, Williams JV, Campbell AP, Patel M, Gerber SI, Halasa NB

Journal of the Pediatric Infectious Diseases Society.. 2022 July 18 Epub 07/18/2022.

Combination of NKG2A and PD-1 Blockade Improves Radiotherapy Response in Radioresistant Tumors.

Battaglia NG, Murphy JD, Uccello TP, Hughson A, Gavras NW, Caldon JJ, Gerber SA, Lord EM

The Journal of immunology : official journal of the American Association of Immunologists.. 2022 July 15 Epub 07/15/2022.

Toll-like receptor 7/8 agonist R848 alters the immune tumor microenvironment and enhances SBRT-induced antitumor efficacy in murine models of pancreatic cancer.

Ye J, Mills BN, Qin SS, Garrett-Larsen J, Murphy JD, Uccello TP, Han BJ, Vrooman TG, Johnston CJ, Lord EM, Belt BA, Linehan DC, Gerber SA

Journal for immunotherapy of cancer.. 2022 July 10 (7)Epub 1900 01 01.

Identification of a Vitamin-D Receptor Antagonist, MeTC7, which Inhibits the Growth of Xenograft and Transgenic Tumors .

Khazan N, Kim KK, Hansen JN, Singh NA, Moore T, Snyder CWA, Pandita R, Strawderman M, Fujihara M, Takamura Y, Jian Y, Battaglia N, Yano N, Teramoto Y, Arnold LA, Hopson R, Kishor K, Nayak S, Ojha D, Sharon A, Ashton JM, Wang J, Milano MT, Miyamoto H, Linehan DC, Gerber SA, Kawar N, Singh AP, Tabdanov ED, Dokholyan NV, Kakuta H, Jurutka PW, Schor NF, Rowswell-Turner RB, Singh RK, Moore RG

Journal of medicinal chemistry.. 2022 April 11 Epub 04/11/2022.

Bladder Cancer Extracellular Vesicles Elicit a CD8 T Cell-Mediated Antitumor Immunity.

Ortiz-Bonilla CJ, Uccello TP, Gerber SA, Lord EM, Messing EM, Lee YF

International journal of molecular sciences.. 2022 March 823 (6)Epub 03/08/2022.

Development of an Orthotopic Murine Model of Rectal Cancer in Conjunction With Targeted Short-Course Radiation Therapy.

Uccello TP, Kintzel SA, Mills BN, Murphy JD, Garrett-Larsen J, Battaglia NG, Rodriguez CJ, Drage MG, Ye J, Love TMT, Johnston CJ, Repasky EA, Qiu H, Linehan DC, Lord EM, Gerber SA

Advances in radiation oncology.. 2022 7 (2):100867. Epub 12/09/2021.

Modulation of the Human Pancreatic Ductal Adenocarcinoma Immune Microenvironment by Stereotactic Body Radiotherapy.

Mills BN, Qiu H, Drage MG, Chen C, Mathew JS, Garrett-Larsen J, Ye J, Uccello TP, Murphy JD, Belt BA, Lord EM, Katz AW, Linehan DC, Gerber SA

Clinical cancer research : an official journal of the American Association for Cancer Research.. 2021 December 3 Epub 12/03/2021.

Intertumoral Genetic Heterogeneity Generates Distinct Tumor Microenvironments in a Novel Murine Synchronous Melanoma Model.

Qin SS, Han BJ, Williams A, Jackson KM, Jewell R, Chacon AC, Lord EM, Linehan DC, Kim M, Reuben A, Gerber SA, Prieto PA

Cancers.. 2021 May 1113 (10)Epub 05/11/2021.

Increased myocellular lipid and IGFBP-3 expression in a pre-clinical model of pancreatic cancer-related skeletal muscle wasting.

Cole CL, Bachman JF, Ye J, Murphy J, Gerber SA, Beck CA, Boyce BF, Muthukrishnan G, Chakkalakal JV, Schwarz EM, Linehan D

Journal of cachexia, sarcopenia and muscle.. 2021 May 7 Epub 05/07/2021.

Co-administration of a clinically relevant dexamethasone dosage with ablative radiotherapy reduces peripheral lymphocytes but does not alter in vivo intratumoral lymphocyte phenotype or inhibit efficacy of radiotherapy in a murine colorectal tumor model.

Battaglia NG, Uccello TP, Hughson A, Garrett-Larsen J, Caldon JJ, Qiu H, Gerber SA, Lord EM

International journal of radiation oncology, biology, physics.. 2021 April 29 Epub 04/29/2021.

H-scan, Shear Wave and Bioluminescent Assessment of the Progression of Pancreatic Cancer Metastases in the Liver.

Baek J, Ahmed R, Ye J, Gerber SA, Parker KJ, Doyley MM

Ultrasound in medicine & biology.. 2020 September 6 Epub 09/06/2020.

SARS-CoV-2 Infections in Children - Multi-Center Surveillance, United States, January-March 2020.

Rha B, Lively JY, Englund JA, Staat MA, Weinberg GA, Selvarangan R, Halasa NB, Williams JV, Boom JA, Sahni LC, Michaels MG, Stewart LS, Harrison CJ, Szilagyi PG, McNeal MM, Klein EJ, Strelitz B, Lacombe K, Schlaudecker E, Moffatt ME, Schuster JE, Pahud BA, Weddle G, Hickey RW, Avadhanula V, Wikswo ME, Hall AJ, Curns AT, Gerber SI, Langley G

Journal of the Pediatric Infectious Diseases Society.. 2020 June 18 Epub 06/18/2020.

Respiratory Syncytial Virus-Associated Hospitalizations Among Young Children: 2015-2016.

Rha B, Curns AT, Lively JY, Campbell AP, Englund JA, Boom JA, Azimi PH, Weinberg GA, Staat MA, Selvarangan R, Halasa NB, McNeal MM, Klein EJ, Harrison CJ, Williams JV, Szilagyi PG, Singer MN, Sahni LC, Figueroa-Downing D, McDaniel D, Prill MM, Whitaker BL, Stewart LS, Schuster JE, Pahud BA, Weddle G, Avadhanula V, Munoz FM, Piedra PA, Payne DC, Langley G, Gerber SI

Pediatrics.. 2020 June 16 Epub 06/16/2020.

Microspheres Encapsulating Immunotherapy Agents Target the Tumor-Draining Lymph Node in Pancreatic Ductal Adenocarcinoma.

Han BJ, Murphy JD, Qin S, Ye J, Uccello TP, Garrett-Larsen J, Belt BA, Prieto PA, Egilmez NK, Lord EM, Linehan DC, Mills BN, Gerber SA

Immunological investigations.. 2020 June 4 :1-16. Epub 06/04/2020.

Shear Wave Elastography Can Differentiate between Radiation-Responsive and Non-responsive Pancreatic Tumors: An ex Vivo Study with Murine Models.

Wang H, Mills B, Mislati R, Ahmed R, Gerber SA, Linehan D, Doyley MM

Ultrasound in medicine & biology.. 2020 February 46 (2):393-404. Epub 11/11/2019.

Dual Energy X-ray Absorptiometry (DEXA) as a longitudinal outcome measure of cancer-related muscle wasting in mice.

Cole CL, Beck CA, Robinson D, Ye J, Mills B, Gerber SA, Schwarz EM, Linehan D

PloS one.. 2020 15 (6):e0230695. Epub 06/19/2020.

Assessing the Magnitude of Immunogenic Cell Death Following Chemotherapy and Irradiation Reveals a New Strategy to Treat Pancreatic Cancer.

Ye J, Mills BN, Zhao T, Han BJ, Murphy JD, Patel AP, Johnston CJ, Lord EM, Belt BA, Linehan DC, Gerber SA

Cancer immunology research.. 2019 November 12 Epub 11/12/2019.

Stereotactic Body Radiation and Interleukin-12 Combination Therapy Eradicates Pancreatic Tumors by Repolarizing the Immune Microenvironment.

Mills BN, Connolly KA, Ye J, Murphy JD, Uccello TP, Han BJ, Zhao T, Drage MG, Murthy A, Qiu H, Patel A, Figueroa NM, Johnston CJ, Prieto PA, Egilmez NK, Belt BA, Lord EM, Linehan DC, Gerber SA

Cell reports.. 2019 October 829 (2):406-421.e5. Epub 1900 01 01.

Intratumoral Hypoxia Reduces IFN-?-Mediated Immunity and MHC Class I Induction in a Preclinical Tumor Model.

Murthy A, Gerber SA, Koch CJ, Lord EM

ImmunoHorizons.. 2019 April 293 (4):149-160. Epub 04/29/2019.

Adrenergic Receptor Signaling Regulates the Response of Tumors to Ionizing Radiation.

MacDonald CR, Bucsek MJ, Qiao G, Chen M, Evans L, Greenberg DJ, Uccello TP, Battaglia NG, Hylander BL, Singh AK, Lord EM, Gerber SA, Repasky EA

Radiation research.. 2019 April 25 Epub 04/25/2019.

Plane-Wave Imaging Improves Single-Track Location Shear Wave Elasticity Imaging.

Ahmed R, Gerber SA, McAleavey SA, Schifitto G, Doyley MM

IEEE transactions on ultrasonics, ferroelectrics, and frequency control.. 2018 August 65 (8):1402-1414. Epub 06/01/2018.

Environmental cues received during development shape dendritic cell responses later in life.

Meyers JL, Winans B, Kelsaw E, Murthy A, Gerber S, Lawrence BP

PloS one.. 2018 13 (11):e0207007. Epub 11/09/2018.

Increasing the efficacy of radiotherapy by modulating the CCR2/CCR5 chemokine axes.

Connolly KA, Belt BA, Figueroa NM, Murthy A, Patel A, Kim M, Lord EM, Linehan DC, Gerber SA

Oncotarget.. 2016 December 277 (52):86522-86535. Epub 1900 01 01.

Total-Body Irradiation Exacerbates Dissemination of Cutaneous Candida Albicans Infection.

Barlow ML, Cummings RJ, Pentland AP, Love TM, Haidaris CG, Ryan JL, Lord EM, Gerber SA

Radiation research.. 2016 November 186 (5):436-446. Epub 10/06/2016.

Live Imaging of Influenza Infection of the Trachea Reveals Dynamic Regulation of CD8+ T Cell Motility by Antigen.

Lambert Emo K, Hyun YM, Reilly E, Barilla C, Gerber S, Fowell D, Kim M, Topham DJ

PLoS pathogens.. 2016 September 12 (9):e1005881. Epub 09/19/2016.

Whole mount immunofluorescence analysis of placentas from normotensive versus preeclamptic pregnancies.

Zozzaro-Smith PE, Bushway ME, Gerber SA, Hebert D, Pressman EK, Lord EM, Miller RK, Murphy SP

Placenta.. 2015 November 36 (11):1310-7. Epub 09/10/2015.

Interleukin-12 preserves the cutaneous physical and immunological barrier after radiation exposure.

Gerber SA, Cummings RJ, Judge JL, Barlow ML, Nanduri J, Johnson DE, Palis J, Pentland AP, Lord EM, Ryan JL

Radiation research.. 2015 January 183 (1):72-81. Epub 01/07/2015.

Radio-responsive tumors exhibit greater intratumoral immune activity than nonresponsive tumors.

Gerber SA, Lim JY, Connolly KA, Sedlacek AL, Barlow ML, Murphy SP, Egilmez NK, Lord EM

International journal of cancer.. 2014 May 15134 (10):2383-92. Epub 11/11/2013.

Morphological and phenotypic analyses of the human placenta using whole mount immunofluorescence.

Bushway ME, Gerber SA, Fenton BM, Miller RK, Lord EM, Murphy SP

Biology of reproduction.. 2014 May 90 (5):110. Epub 03/19/2014.

Optogenetic control of chemokine receptor signal and T-cell migration.

Xu Y, Hyun YM, Lim K, Lee H, Cummings RJ, Gerber SA, Bae S, Cho TY, Lord EM, Kim M

Proceedings of the National Academy of Sciences of the United States of America.. 2014 April 29111 (17):6371-6. Epub 04/14/2014.

Type I interferons induced by radiation therapy mediate recruitment and effector function of CD8(+) T cells.

Lim JY, Gerber SA, Murphy SP, Lord EM

Cancer immunology, immunotherapy : CII.. 2014 March 63 (3):259-71. Epub 12/20/2013.

G-protein-coupled receptor-2-interacting protein-1 is required for endothelial cell directional migration and tumor angiogenesis via cortactin-dependent lamellipodia formation.

Majumder S, Sowden MP, Gerber SA, Thomas T, Christie CK, Mohan A, Yin G, Lord EM, Berk BC, Pang J

Arteriosclerosis, thrombosis, and vascular biology.. 2014 February 34 (2):419-26. Epub 11/21/2013.

Uterine natural killer cells pace early development of mouse decidua basalis.

Hofmann AP, Gerber SA, Croy BA

Molecular human reproduction.. 2014 January 20 (1):66-76. Epub 09/01/2013.

Radiation therapy combined with -based cancer vaccine synergize to enhance tumor control in the B16 melanoma model.

Lim JY, Brockstedt DG, Lord EM, Gerber SA

Oncoimmunology.. 2014 3 :e29028. Epub 06/03/2014.

Generation of a dual-functioning antitumor immune response in the peritoneal cavity.

Sedlacek AL, Gerber SA, Randall TD, van Rooijen N, Frelinger JG, Lord EM

The American journal of pathology.. 2013 October 183 (4):1318-1328. Epub 08/08/2013.

Directional Histogram Ratio at Random Probes: A Local Thresholding Criterion for Capillary Images.

Lu N, Silva J, Gu Y, Gerber S, Wu H, Gelbard H, Dewhurst S, Miao H

Pattern recognition. 2013 July 146 (7):1933-1948. Epub 01/18/2013.

IFN-? mediates the antitumor effects of radiation therapy in a murine colon tumor.

Gerber SA, Sedlacek AL, Cron KR, Murphy SP, Frelinger JG, Lord EM

The American journal of pathology.. 2013 June 182 (6):2345-54. Epub 04/12/2013.

Local expression of interleukin-2 by B16 melanoma cells results in decreased tumour growth and long-term tumour dormancy.

Gerber SA, Sorensen EW, Sedlacek AL, Lim JY, Skrombolas D, Frelinger JG, Lord EM

Immunology.. 2013 March 138 (3):280-92. Epub 1900 01 01.

Changes in ovarian tumor cell number, tumor vasculature, and T cell function monitored in vivo using a novel xenograft model.

Yokota SJ, Facciponte JG, Kelleher RJ, Shultz LD, Loyall JL, Parsons RR, Odunsi K, Frelinger JG, Lord EM, Gerber SA, Balu-Iyer SV, Bankert RB

Cancer immunity. 2013 13 :11. Epub 05/31/2013.

Exposure to ionizing radiation induces the migration of cutaneous dendritic cells by a CCR7-dependent mechanism.

Cummings RJ, Gerber SA, Judge JL, Ryan JL, Pentland AP, Lord EM

The Journal of immunology : official journal of the American Association of Immunologists.. 2012 November 1189 (9):4247-57. Epub 09/21/2012.

Imaging of vascular development in early mouse decidua and its association with leukocytes and trophoblasts.

Croy BA, Chen Z, Hofmann AP, Lord EM, Sedlacek AL, Gerber SA

Biology of reproduction.. 2012 November 87 (5):125. Epub 11/29/2012.

Emerging themes in uterine natural killer cell heterogeneity and function.

Hatta K, MacLeod RJ, Gerber SA, Croy BA

American journal of reproductive immunology : AJRI.. 2012 October 68 (4):282-9. Epub 05/24/2012.

An implantable vascularized protein gel construct that supports human fetal hepatoblast survival and infection by hepatitis C virus in mice.

Harding MJ, Lepus CM, Gibson TF, Shepherd BR, Gerber SA, Graham M, Paturzo FX, Rahner C, Madri JA, Bothwell AL, Lindenbach BD, Pober JS

PloS one.. 2010 April 15 (4):e9987. Epub 04/01/2010.

IL-12 suppresses vascular endothelial growth factor receptor 3 expression on tumor vessels by two distinct IFN-gamma-dependent mechanisms.

Sorensen EW, Gerber SA, Frelinger JG, Lord EM

The Journal of immunology : official journal of the American Association of Immunologists.. 2010 February 15184 (4):1858-66. Epub 01/08/2010.

Omental immune aggregates and tumor metastasis within the peritoneal cavity.

Sorensen EW, Gerber SA, Sedlacek AL, Rybalko VY, Chan WM, Lord EM

Immunologic research.. 2009 December 45 (2-3):185-94. Epub 02/28/2009.

Comparison of human fetal liver, umbilical cord blood, and adult blood hematopoietic stem cell engraftment in NOD-scid/gammac-/-, Balb/c-Rag1-/-gammac-/-, and C.B-17-scid/bg immunodeficient mice.

Lepus CM, Gibson TF, Gerber SA, Kawikova I, Szczepanik M, Hossain J, Ablamunits V, Kirkiles-Smith N, Herold KC, Donis RO, Bothwell AL, Pober JS, Harding MJ

Human immunology.. 2009 October 70 (10):790-802. Epub 06/12/2009.

Interferon-gamma induces prolyl hydroxylase (PHD)3 through a STAT1-dependent mechanism in human endothelial cells.

Gerber SA, Yatsula B, Maier CL, Sadler TJ, Whittaker LW, Pober JS

Arteriosclerosis, thrombosis, and vascular biology.. 2009 September 29 (9):1363-9. Epub 07/02/2009.

Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis.

Suárez Y, Fernández-Hernando C, Yu J, Gerber SA, Harrison KD, Pober JS, Iruela-Arispe ML, Merkenschlager M, Sessa WC

Proceedings of the National Academy of Sciences of the United States of America.. 2008 September 16105 (37):14082-7. Epub 09/08/2008.

IFN-alpha induces transcription of hypoxia-inducible factor-1alpha to inhibit proliferation of human endothelial cells.

Gerber SA, Pober JS

The Journal of immunology : official journal of the American Association of Immunologists.. 2008 July 15181 (2):1052-62. Epub 1900 01 01.

Radiation-induced IFN-gamma production within the tumor microenvironment influences antitumor immunity.

Lugade AA, Sorensen EW, Gerber SA, Moran JP, Frelinger JG, Lord EM

The Journal of immunology : official journal of the American Association of Immunologists.. 2008 March 1180 (5):3132-9. Epub 1900 01 01.

Preferential attachment of peritoneal tumor metastases to omental immune aggregates and possible role of a unique vascular microenvironment in metastatic survival and growth.

Gerber SA, Rybalko VY, Bigelow CE, Lugade AA, Foster TH, Frelinger JG, Lord EM

The American journal of pathology.. 2006 November 169 (5):1739-52. Epub 1900 01 01.

Local radiation therapy of B16 melanoma tumors increases the generation of tumor antigen-specific effector cells that traffic to the tumor.

Lugade AA, Moran JP, Gerber SA, Rose RC, Frelinger JG, Lord EM

The Journal of immunology : official journal of the American Association of Immunologists.. 2005 June 15174 (12):7516-23. Epub 1900 01 01.

Characterization of a lymph node within the mouse prostate: Detailed analysis using whole mount histology.

Gerber SA, Turner MJ, Lugade AA, Moran JP, Frelinger JG, Lord EM

The Prostate.. 2005 May 163 (2):105-16. Epub 1900 01 01.

Transfection of the genes for interleukin-12 into the K1735 melanoma and the EMT6 mammary sarcoma murine cell lines reveals distinct mechanisms of antitumor activity.

Moran JP, Gerber SA, Martin CA, Frelinger JG, Lord EM

International journal of cancer.. 2003 September 20106 (5):690-8. Epub 1900 01 01.

Mechanism of IL-12 mediated alterations in tumour blood vessel morphology: analysis using whole-tissue mounts.

Gerber SA, Moran JP, Frelinger JG, Frelinger JA, Fenton BM, Lord EM

British journal of cancer.. 2003 May 688 (9):1453-61. Epub 1900 01 01.

Human papillomavirus virus-like particles are efficient oral immunogens when coadministered with Escherichia coli heat-labile enterotoxin mutant R192G or CpG DNA.

Gerber S, Lane C, Brown DM, Lord E, DiLorenzo M, Clements JD, Rybicki E, Williamson AL, Rose RC

Journal of virology.. 2001 May 75 (10):4752-60. Epub 1900 01 01.