Fabeha Fazal, Ph.D.

Fabeha Fazal, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 850
Rochester, NY 14642

Office: (585) 275-9917
Fax: (585) 756-7780
Administrative: (585) 275-5948

Journal Articles

Showing all 18 journal articles available.

2014
Bijli KM, Kanter BG, Minhajuddin M, Leonard A, Xu L, Fazal F, Rahman A. "Regulation of endothelial cell inflammation and lung polymorphonuclear lymphocyte infiltration by transglutaminase 2." Shock. 2014 42(6):562-9.
2014
Leonard A, Paton AW, El-Quadi M, Paton JC, Fazal F. "Preconditioning with endoplasmic reticulum stress ameliorates endothelial cell inflammation." PloS one. 2014 9(10):e110949. Epub 2014 Oct 30.
2013 Nov 1
Leonard A, Marando C, Rahman A, Fazal F. "Thrombin selectively engages LIM kinase 1 and slingshot-1L phosphatase to regulate NF-?B activation and endothelial cell inflammation." American journal of physiology. Lung cellular and molecular physiology. 2013 Nov 1; 305(9):L651-64. Epub 2013 Sep 13.
2013
Fazal F, Bijli KM, Murrill M, Leonard A, Minhajuddin M, Anwar KN, Finkelstein JN, Watterson DM, Rahman A. "Critical role of non-muscle myosin light chain kinase in thrombin-induced endothelial cell inflammation and lung PMN infiltration." PloS one. 2013 8(3):e59965. Epub 2013 Mar 21.
2012 Nov
Bijli KM, Fazal F, Rahman A. "Regulation of Rela/p65 and endothelial cell inflammation by proline-rich tyrosine kinase 2." American journal of respiratory cell and molecular biology. 2012 Nov; 47(5):660-8. Epub 2012 Jul 27.
2011 Nov
Rahman A, Fazal F. "Blocking NF-?B: an inflammatory issue." Proceedings of the American Thoracic Society. 2011 Nov; 8(6):497-503.
2011 Aug 15
Yang L, Chen G, Mohanty S, Scott G, Fazal F, Rahman A, Begum S, Hynes R, Xu L. "GPR56 Regulates VEGF production and angiogenesis during melanoma progression." Cancer research. 2011 Aug 15; 71(16):5558-68. Epub 2011 Jul 01.
2009 Jul 31
Fazal F, Bijli KM, Minhajuddin M, Rein T, Finkelstein JN, Rahman A. "Essential role of cofilin-1 in regulating thrombin-induced RelA/p65 nuclear translocation and intercellular adhesion molecule 1 (ICAM-1) expression in endothelial cells." The Journal of biological chemistry. 2009 Jul 31; 284(31):21047-56. Epub 2009 May 29.
2009 Apr
Rahman A, Fazal F. "Hug tightly and say goodbye: role of endothelial ICAM-1 in leukocyte transmigration." Antioxidants & redox signaling. 2009 Apr; 11(4):823-39.
2009 Feb 13
Minhajuddin M, Bijli KM, Fazal F, Sassano A, Nakayama KI, Hay N, Platanias LC, Rahman A. "Protein kinase C-delta and phosphatidylinositol 3-kinase/Akt activate mammalian target of rapamycin to modulate NF-kappaB activation and intercellular adhesion molecule-1 (ICAM-1) expression in endothelial cells." The Journal of biological chemistry. 2009 Feb 13; 284(7):4052-61. Epub 2008 Dec 13.
2008 May 23
Bijli KM, Fazal F, Minhajuddin M, Rahman A. "Activation of Syk by protein kinase C-delta regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via tyrosine phosphorylation of RelA/p65." The Journal of biological chemistry. 2008 May 23; 283(21):14674-84. Epub 2008 Mar 24.
2007 Feb 9
Fazal F, Minhajuddin M, Bijli KM, McGrath JL, Rahman A. "Evidence for actin cytoskeleton-dependent and -independent pathways for RelA/p65 nuclear translocation in endothelial cells." The Journal of biological chemistry. 2007 Feb 9; 282(6):3940-50. Epub 2006 Dec 08.
2007 Feb
Bijli KM, Minhajuddin M, Fazal F, O'Reilly MA, Platanias LC, Rahman A. "c-Src interacts with and phosphorylates RelA/p65 to promote thrombin-induced ICAM-1 expression in endothelial cells." American journal of physiology. Lung cellular and molecular physiology. 2007 Feb; 292(2):L396-404. Epub 2006 Sep 29.
2005 Jul
Fazal F, Gu L, Ihnatovych I, Han Y, Hu W, Antic N, Carreira F, Blomquist JF, Hope TJ, Ucker DS, de Lanerolle P. "Inhibiting myosin light chain kinase induces apoptosis in vitro and in vivo." Molecular and cellular biology. 2005 Jul; 25(14):6259-66.
2005 May 1
Minhajuddin M, Fazal F, Bijli KM, Amin MR, Rahman A. "Inhibition of mammalian target of rapamycin potentiates thrombin-induced intercellular adhesion molecule-1 expression by accelerating and stabilizing NF-kappa B activation in endothelial cells." The Journal of immunology : official journal of the American Association of Immunologists. 2005 May 1; 174(9):5823-9.
2004
Anwar KN, Fazal F, Malik AB, Rahman A. "RhoA/Rho-associated kinase pathway selectively regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via activation of I kappa B kinase beta and phosphorylation of RelA/p65." The Journal of immunology : official journal of the American Association of Immunologists. 2004 173(11):6965-72.
2003 Mar
Nobe H, Nobe K, Fazal F, De Lanerolle P, Paul RJ. "Rho kinase mediates serum-induced contraction in fibroblast fibers independent of myosin LC20 phosphorylation." American journal of physiology. Cell physiology. 2003 Mar; 284(3):C599-606. Epub 2002 Oct 03.
1995 Jun 1
Adami C, Pooley J, Glomb J, Stecker E, Fazal F, Fleming JO, Baker SC. "Evolution of mouse hepatitis virus (MHV) during chronic infection: quasispecies nature of the persisting MHV RNA." Virology. 1995 Jun 1; 209(2):337-46.

Books

1993
Rahman A, Fazal F, Hadi SM. "Strand scission in DNA induced by dietary flavonoids: Role of Cu (II) and oxygen free radicals.". Glimpses in Plant Research XI: Medicinal Plants; New Vistas of Research [Part 2]. Govil JN, Singh VK, Hashmi S. New Delhi, India: Today and Tomorrow's Printers and Publishers, 1993. 361-370