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Hani A. Awad, Ph.D.

Contact Information

Phone Numbers

Office: (585) 273-5268

Research Labs

My Laboratory interfaces Biomedical Engineering and Orthopaedics. We provide opportunities for state of the art training related to Tissue Engineering and Biomechanics.

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Research Network

Biography

My research focuses primarily on Musculoskeletal Tissue Engineering with an emphasis on challenging clinical problems and translational solutions. Our approach is to develop in vivo and in vitro models of musculoskeletal injury and clinically-translatable outcome measures to assess the efficacy of regenerative and tissue engineering solutions.

Professional Background

I completed my graduate work at the University of Cincinnati under the mentorship of Dr. David Butler, a leading expert in tendon and ligament injury and repair, and having later completed a post-doctoral fellowship with Dr. Farshid Guilak at Duke University, at one of the leading orthopaedic research laboratories in the country. In the Fall of 2004, I joined the faculty of the University of Rochester as an Assistant Professor in the Departments of Orthopaedics and Biomedical Engineering. My research focuses primarily on tissue engineering of load bearing connective tissues, including ligament and tendon, cartilage, and bone.

Research

My research focuses primarily on Musculoskeletal Tissue Engineering with an emphasis on challenging clinical problems and translational solutions.
Our approach is to develop in vivo and in vitro models of musculoskeletal injury and clinically-translatable outcome measures to assess the efficacy of regenerative and tissue engineering solutions.
Current research projects include:

1. Tissue Engineering of Massive Bone Allograft Union
2. Allografts and Gdf5 Gene Therapy in Flexor Tendon Tissue Engineering
3. Modulating Stem Cell Differentiation using Novel Allograft Scaffolds for Cartilage Repair
4. Fashioning a Superficial Zone-Like Layer in Bioreactor-Cultivated Tissue Engineered Cartilage
5. Evaluating models of human musculoskeletal disease and trauma

Credentials

Faculty Appointments

Education

1993
BS | University of Jordan
Mechanical Engineering

1999
PhD | University of Cincinnati
Engineering Mechanics/Biomechanics

1995
MS | University of Cincinnati
Engineering Mechanics/Biomechanics

Awards

2007
Kappa Delta - Ann Doner Vaughan Award
Sponsor: ORS/AAOS

2005
Early Career Translational Research Award in Biomedical Engineering
Sponsor: Wallace H. Coulter Foundation

1998
Finalist, PhD Student Presentation Competition
Sponsor: ASME IMEC&E – Bioengineering Division

1997
Finalist, PhD Student Presentation Competition
Sponsor: ASME Bioengineering Division

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Patents

Title: Protecting and Repairing Cartilage and Musculoskeletal Soft Tissues
U.S. Serial #: 13/971,366
Filed: Aug 20, 2013
Invented By: HaniAwad, SusanBukata, RegisO'Keefe, J. EdwardPuzas, RandyRosier, ErikSampson, MichaelZuscik

Title: Protecting and Repairing Cartilage and Musculoskeletal Soft Tissues
U.S. Serial #: 13/124,002
Filed: Oct 13, 2009
Invented By: HaniAwad, SusanBukata, RegisO'Keefe, J. EdwardPuzas, RandyRosier, ErikSampson, MichaelZuscik

Publications

Journal Articles

5/17/2017
Bez M, Sheyn D, Tawackoli W, Avalos P, Shapiro G, Giaconi JC, Da X, David SB, Gavrity J, Awad HA, Bae HW, Ley EJ, Kremen TJ, Gazit Z, Ferrara KW, Pelled G, Gazit D. "In situ bone tissue engineering via ultrasound-mediated gene delivery to endogenous progenitor cells in mini-pigs." Science translational medicine.. 2017 May 17; 9(390)

1/2017
Trombetta R, Inzana JA, Schwarz EM, Kates SL, Awad HA. "3D Printing of Calcium Phosphate Ceramics for Bone Tissue Engineering and Drug Delivery." Annals of biomedical engineering.. 2017 Jan 0; 45(1):23-44. Epub 2016 Jun 20.

2017
Beier EE, Sheu TJ, Resseguie EA, Takahata M, Awad HA, Cory-Slechta DA, Puzas JE. "Sclerostin activity plays a key role in the negative effect of glucocorticoid signaling on osteoblast function in mice." Bone research.. 2017 5:17013. Epub 2017 May 09.

Books & Chapters

2003
Chapter Title: Assessment of function in Tendon and Ligament Repair
Book Title: Functional Tissue Engineering
Author List: Butler D, Dressler M, Awad H
Edited By: F Guilak, DL Butler, SA Goldstein, DJ Mooney
Published By: Springer-Verlag2003 in New York, NY

2002
Chapter Title: Biomaterials for Cartilage Tissue Engineering
Book Title: Tissue Engineering and Biodegradable Equivalents
Author List: Awad H, Erickson G, Guilak F
Edited By: K-U Lewandrowski, DL Wise, DJ Trantolo, JD Gresser, MJ Yaszemski, DE Altobelli
Published By: Marcel Dekker Inc.2002 in New York, NY

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