Hani A. Awad, Ph.D.

Hani A. Awad, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 665
Rochester, NY 14642

Office: (585) 273-5268

Lab Information

My Laboratory interfaces Biomedical Engineering and Orthopaedics. We provide opportunities for state of the art training related to Tissue Engineering and Biomechanics.

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Professional Bio

I completed my graduate work at the University of Cincinnati under the mentorship of Dr. David Butler, a leading expert in tendon and ligament injury and repair, and having later completed a post-doctoral fellowship with Dr. Farshid Guilak at Duke University, at one of the leading orthopaedic research laboratories in the country. In the Fall of 2004, I joined the faculty of the University of Rochester as an Assistant Professor in the Departments of Orthopaedics and Biomedical Engineering. My research focuses primarily on tissue engineering of load bearing connective tissues, including ligament and tendon, cartilage, and bone.

Research Bio

My research focuses primarily on Musculoskeletal Tissue Engineering with an emphasis on challenging clinical problems and translational solutions.
Our approach is to develop in vivo and in vitro models of musculoskeletal injury and clinically-translatable outcome measures to assess the efficacy of regenerative and tissue engineering solutions.
Current research projects include:



1. Tissue Engineering of Massive Bone Allograft Union
2. Allografts and Gdf5 Gene Therapy in Flexor Tendon Tissue Engineering
3. Modulating Stem Cell Differentiation using Novel Allograft Scaffolds for Cartilage Repair
4. Fashioning a Superficial Zone-Like Layer in Bioreactor-Cultivated Tissue Engineered Cartilage
5. Evaluating models of human musculoskeletal disease and trauma

Awards & Honors (National)

Kappa Delta - Ann Doner Vaughan Award | ORS/AAOS 2007
Early Career Translational Research Award in Biomedical Engineering | Wallace H. Coulter Foundation 2005

Awards & Honors (Local)

Finalist, PhD Student Presentation Competition | ASME IMEC&E – Bioengineering Division 1998
Finalist, PhD Student Presentation Competition | ASME Bioengineering Division 1997

Patents

Freeze-Dried Tendon Allografts as Delivery Vehicles for Genes

United States Serial NO.: 12/513,161
Filed Date: October 31, 2007
Title: Targeted Delivery of Therapeutic Agents With Lyophilized Matrices
Invented by: Hani Awad, Edward Schwarz
Repair and Regeneration of Articular Cartilage, and the Repair and Regeneration of Fibrocartilaginous Tissues

United States Serial NO.: 13/124,002
Filed Date: October 13, 2009
Title: Protecting and Repairing Cartilage and Musculoskeletal Soft Tissues
Invented by: Randy Rosier, Michael Zuscik, Erik Sampson, Susan Bukata, J. Edward Puzas, Regis O'Keefe, Hani Awad
Repair and Regeneration of Articular Cartilage, and the Repair and Regeneration of Fibrocartilaginous Tissues

United States Serial NO.: 13/971,366
Filed Date: August 20, 2013
Title: Protecting and Repairing Cartilage and Musculoskeletal Soft Tissues
Invented by: Randy Rosier, Michael Zuscik, Erik Sampson, Susan Bukata, J. Edward Puzas, Regis O'Keefe, Hani Awad

Recent Journal Articles

Showing the 5 most recent journal articles. 93 available »

2016 Jun 20
Trombetta R, Inzana JA, Schwarz EM, Kates SL, Awad HA. "3D Printing of Calcium Phosphate Ceramics for Bone Tissue Engineering and Drug Delivery." Annals of biomedical engineering. 2016 Jun 20; Epub 2016 Jun 20.
2016 Mar
Inzana JA, Schwarz EM, Kates SL, Awad HA. "Biomaterials approaches to treating implant-associated osteomyelitis." Biomaterials. 2016 Mar; 81:58-71. Epub 2015 Dec 18.
2015 Jul
Yaseen Z, English C, Stanbury SJ, Chen T, Messing S, Awad H, Elfar JC. "The Effect of the Epitendinous Suture on Gliding in a Cadaveric Model of Zone II Flexor Tendon Repair." The Journal of hand surgery. 2015 Jul; 40(7):1363-8. Epub 2015 Apr 25.
2015 Jun
Loiselle AE, Yukata K, Geary MB, Kondabolu S, Shi S, Jonason JH, Awad HA, O'Keefe RJ. "Development of antisense oligonucleotide (ASO) technology against Tgf-? signaling to prevent scarring during flexor tendon repair." Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2015 Jun; 33(6):859-66.
2015 Apr
Wang C, Shen J, Yukata K, Inzana JA, O'Keefe RJ, Awad HA, Hilton MJ. "Transient gamma-secretase inhibition accelerates and enhances fracture repair likely via Notch signaling modulation." Bone. 2015 Apr; 73:77-89. Epub 2014 Dec 16.

Current Appointments

Professor - Department of Biomedical Engineering (SMD) - Primary
Professor - Department of Orthopaedics (SMD)
Professor - Center for Musculoskeletal Research

Education

PhD | Engineering Mechanics/Biomechanics | University of Cincinnati1999
MS | Engineering Mechanics/Biomechanics | University of Cincinnati1995
BS | Mechanical Engineering | University of Jordan1993

Post-Doctoral Training & Residency

Bioengineering Laboratory (Mentor: Farshid Guilak), Department of Surgery - Division of Orthopaedic Surgery, Duke University 2004