Skip to main content

Coronavirus (COVID-19): Visitor Restrictions, Resources, and Updates

Explore URMC

Jermaine L. Jenkins, Ph.D.


Showing all 30 journal articles & 0 books available

Journal Articles

Sparks RP, Arango AS, Starr ML, Aboff ZL, Hurst LR, Rivera-Kohr DA, Zhang C, Harden KA, Jenkins JL, Guida WC, Tajkhorshid E, Fratti RA. "A small-molecule competitive inhibitor of phosphatidic acid binding by the AAA+ protein NSF/Sec18 blocks the SNARE-priming stage of vacuole fusion." The Journal of biological chemistry.. 2019 Sep 12; Epub 2019 Sep 12.

Talkish J, Igel H, Hunter O, Horner SW, Jeffery NN, Leach JR, Jenkins JL, Kielkopf CL, Ares M. "Cus2 enforces the first ATP-dependent step of splicing by binding to yeast SF3b1 through a UHM-ULM interaction." RNA.. 2019 Aug 0; 25(8):1020-1037. Epub 2019 May 20.

Hilt ZT, Pariser DN, Ture SK, Mohan A, Quijada P, Asante A, Cameron SJ, Sterling JA, Merkel AR, Johanson AL, Jenkins JL, Small EM, McGrath KE, Palis J, Elliott MR, Morrell CN. "Platelet-derived ?2M regulates monocyte inflammatory responses." JCI insight.. 2019 Jan 31; Epub 2019 Jan 31.

Starr ML, Sparks RP, Arango AS, Hurst LR, Zhao Z, Lihan M, Jenkins JL, Tajkhorshid E, Fratti RA. "Phosphatidic acid induces conformational changes in Sec18 protomers that prevent SNARE priming." The Journal of biological chemistry.. 2019 Jan 7; Epub 2019 Jan 07.

Sparks RP, Jenkins JL, Fratti R. "Use of Surface Plasmon Resonance (SPR) to Determine Binding Affinities and Kinetic Parameters Between Components Important in Fusion Machinery." Methods in molecular biology.. 2019 1860:199-210.

Loerch S, Leach JR, Horner SW, Maji D, Jenkins JL, Pulvino M, Kielkopf CL. "The pre-mRNA splicing and transcription factor Tat-SF1 is a functional partner of the spliceosome SF3b1 subunit via a U2AF homology motif interface." The Journal of biological chemistry.. 2018 Dec 19; Epub 2018 Dec 19.

Glasser E, Agrawal A, Jenkins JL, Kielkopf CL. "Cancer-Associated Mutations Mapped on High-Resolution Structures of the U2AF2 RNA Recognition Motifs." Biochemistry.. 2017 Sep 12; 56(36):4757-4761. Epub 2017 Sep 01.

Wedekind JE, Dutta D, Belashov IA, Jenkins JL. "Metalloriboswitches: RNA-based inorganic ion sensors that regulate genes." The Journal of biological chemistry.. 2017 Jun 9; 292(23):9441-9450. Epub 2017 Apr 28.

Jenkins JL, Kielkopf CL. "Splicing Factor Mutations in Myelodysplasias: Insights from Spliceosome Structures." Trends in genetics : TIG.. 2017 May 0; 33(5):336-348. Epub 2017 Mar 31.

Clark KM, Jenkins JL, Fedoriw N, Dumont ME. "Human CaaX protease ZMPSTE24 expressed in yeast: Structure and inhibition by HIV protease inhibitors." Protein science : a publication of the Protein Society.. 2017 Feb 0; 26(2):242-257. Epub 2016 Nov 11.

Sparks RP, Jenkins JL, Miner GE, Wang Y, Guida WC, Sparks CE, Fratti RA, Sparks JD. "Phosphatidylinositol (3,4,5)-trisphosphate binds to sortilin and competes with neurotensin: Implications for very low density lipoprotein binding." Biochemical and biophysical research communications.. 2016 Oct 21; 479(3):551-556. Epub 2016 Sep 22.

Sparks RP, Guida WC, Sowden MP, Jenkins JL, Starr ML, Fratti RA, Sparks CE, Sparks JD. "Sortilin facilitates VLDL-B100 secretion by insulin sensitive McArdle RH7777 cells." Biochemical and biophysical research communications.. 2016 Sep 16; 478(2):546-52. Epub 2016 Aug 02.

Miralem T, Lerner-Marmarosh N, Gibbs PE, Jenkins JL, Heimiller C, Maines MD. "Interaction of human biliverdin reductase with Akt/protein kinase B and phosphatidylinositol-dependent kinase 1 regulates glycogen synthase kinase 3 activity: a novel mechanism of Akt activation." FASEB journal : official publication of the Federation of American Societies for Experimental Biology.. 2016 Aug 0; 30(8):2926-44. Epub 2016 May 10.

Agrawal AA, Salsi E, Chatrikhi R, Henderson S, Jenkins JL, Green MR, Ermolenko DN, Kielkopf CL. "An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal." Nature communications.. 2016 Mar 8; 7:10950. Epub 2016 Mar 08.

Jenkins JL, Wedekind JE. "The Quick and the Dead: A Guide to Fast Phasing of Small Ribozyme and Riboswitch Crystal Structures." Methods in molecular biology.. 2016 1490:265-80.

Agrawal AA, McLaughlin KJ, Jenkins JL, Kielkopf CL. "Structure-guided U2AF65 variant improves recognition and splicing of a defective pre-mRNA." Proceedings of the National Academy of Sciences of the United States of America.. 2014 Dec 9; 111(49):17420-5. Epub 2014 Nov 24.

Liberman JA, Bogue JT, Jenkins JL, Salim M, Wedekind JE. "ITC analysis of ligand binding to preQ? riboswitches." Methods in enzymology.. 2014 549:435-50.

Jenkins JL, Agrawal AA, Gupta A, Green MR, Kielkopf CL. "U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs." Nucleic acids research.. 2013 Apr 1; 41(6):3859-73. Epub 2013 Feb 01.

Liberman JA, Guo M, Jenkins JL, Krucinska J, Chen Y, Carey PR, Wedekind JE. "A transition-state interaction shifts nucleobase ionization toward neutrality to facilitate small ribozyme catalysis." Journal of the American Chemical Society.. 2012 Oct 17; 134(41):16933-6. Epub 2012 Oct 03.

Jenkins JL, Laird KM, Kielkopf CL. "A Broad range of conformations contribute to the solution ensemble of the essential splicing factor U2AF(65)." Biochemistry.. 2012 Jul 3; 51(26):5223-5. Epub 2012 Jun 19.

Bauer WJ, Heath J, Jenkins JL, Kielkopf CL. "Three RNA recognition motifs participate in RNA recognition and structural organization by the pro-apoptotic factor TIA-1." Journal of molecular biology.. 2012 Jan 27; 415(4):727-40. Epub 2011 Dec 02.

Lippa GM, Liberman JA, Jenkins JL, Krucinska J, Salim M, Wedekind JE. "Crystallographic analysis of small ribozymes and riboswitches." Methods in molecular biology.. 2012 848:159-84.

Jenkins JL, Krucinska J, McCarty RM, Bandarian V, Wedekind JE. "Comparison of a preQ1 riboswitch aptamer in metabolite-bound and free states with implications for gene regulation." The Journal of biological chemistry.. 2011 Jul 15; 286(28):24626-37. Epub 2011 May 18.

McLaughlin KJ, Jenkins JL, Kielkopf CL. "Large favorable enthalpy changes drive specific RNA recognition by RNA recognition motif proteins." Biochemistry.. 2011 Mar 8; 50(9):1429-31. Epub 2011 Feb 02.

Gupta A, Jenkins JL, Kielkopf CL. "RNA induces conformational changes in the SF1/U2AF65 splicing factor complex." Journal of molecular biology.. 2011 Feb 4; 405(5):1128-38. Epub 2010 Dec 10.

Jenkins JL, Shen H, Green MR, Kielkopf CL. "Solution conformation and thermodynamic characteristics of RNA binding by the splicing factor U2AF65." The Journal of biological chemistry.. 2008 Nov 28; 283(48):33641-9. Epub 2008 Oct 08.

Jenkins, J.L; Shen H.; Green M.R.; Kielkopf. "Solution Conformation and Thermodynamic Characteristics of RNA binding by Splicing Factor U2AF65" . J. Biol. Chem. 2008; 283: 33641-33649.

Zhou Y.; Larson J.D.; Bottoms C.A.; Arturo E.C.; Henzl M.T.; Jenkins, J.L; Nix J.C.; Becker D.F.; Tanner, J.J. "Structural Basis of the Transcriptional Regulation of the Proline Utilization Regulon by Multifunctional PutA" . J. Mol. Biol. 2008; 381: 174-188.

Larson, J.D.; Jenkins, J.L.; Schuermann, J.P.; Zhou, Y.; Becker, D.F.; Tanner, J.J. "Crystal Structures of the DNA-binding Domain of Escherichia coli Proline Utilization A Flavoprotein and Analysis of the Role of Lys9 in DNA Recognition" . Protein Science. 2006; v15: 2630-2641.

Jenkins, J.L.; Tanner, J.J. "High Resolution Crystal Structure of Human D-Glyceraldehyde-3-Phosphate Dehydrogenase" . Acta Crystallogr. 2006; D62: 290-301.