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Dmitri N. Ermolenko, Ph.D.

Contact Information

Phone Numbers

Office: (585) 275-3704

Fax: (585) 271-2683

Research Labs

Faculty Appointments

Biography

Research

We are interested in the mechanisms of the ribosome function. The ribosome is a central component of cell metabolism, translating genetic code and synthesizing proteins in all living organism. The ribosome is an extremely complex and highly dynamic machine. Our research is focused on the mechanics of ribosome movement along mRNA during protein synthesis. Movement of ribosomes along mRNA is essential attribute of protein synthesis in all organisms and often used to regulate protein expression.

Publications

Journal Articles

10/18/2018
Lai WC, Kayedkhordeh M, Cornell EV, Farah E, Bellaousov S, Rietmeijer R, Salsi E, Mathews DH, Ermolenko DN. "mRNAs and lncRNAs intrinsically form secondary structures with short end-to-end distances." Nature communications.. 2018 Oct 18; 9(1):4328. Epub 2018 Oct 18.

10/17/2018
Warnasooriya C, Ling C, Belashov IA, Salim M, Wedekind JE, Ermolenko DN. "Observation of preQ-II riboswitch dynamics using single-molecule FRET." RNA biology.. 2018 Oct 17; :1-7. Epub 2018 Oct 17.

3/15/2018
Lai CW, Ermolenko DN. "Ensemble and single-molecule FRET studies of protein synthesis." Methods : a companion to Methods in enzymology.. 2018 Mar 15; 137:37-48. Epub 2017 Dec 13.

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