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Dmitri N. Ermolenko, Ph.D.

Contact Information

Phone Numbers

Office: (585) 275-3704

Fax: (585) 271-2683

Social Links

@DmitriErmolenko

Research Labs

Faculty Appointments

Biography

Research

We are interested in the mechanisms of the ribosome function. The ribosome is a central component of cell metabolism, translating genetic code and synthesizing proteins in all living organism. The ribosome is an extremely complex and highly dynamic machine. Our research is focused on the mechanics of ribosome movement along mRNA during protein synthesis. Movement of ribosomes along mRNA is essential attribute of protein synthesis in all organisms and often used to regulate protein expression.

Publications

Journal Articles

2/21/2022
Bao C, Zhu M, Nykonchuk I, Wakabayashi H, Mathews DH, Ermolenko DN. "Specific length and structure rather than high thermodynamic stability enable regulatory mRNA stem-loops to pause translation." Nature communications.. 2022 Feb 21; 13(1):988. Epub 2022 Feb 21.

8/2021
Bao C, Ermolenko DN. "Ribosome as a Translocase and Helicase." Biochemistry. Biokhimii?a?.. 2021 Aug; 86(8):992-1002.

6/29/2020
Ermolenko DN, Mathews DH. "Making ends meet: New functions of mRNA secondary structure." Wiley interdisciplinary reviews. RNA.. 2020 Jun 29; :e1611. Epub 2020 Jun 29.

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