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Dmitri N. Ermolenko, Ph.D.

Contact Information

Phone Numbers

Office: (585) 275-3704

Fax: (585) 271-2683

Research Labs

Faculty Appointments

Biography

Research

We are interested in the mechanisms of the ribosome function. The ribosome is a central component of cell metabolism, translating genetic code and synthesizing proteins in all living organism. The ribosome is an extremely complex and highly dynamic machine. Our research is focused on the mechanics of ribosome movement along mRNA during protein synthesis. Movement of ribosomes along mRNA is essential attribute of protein synthesis in all organisms and often used to regulate protein expression.

Publications

Journal Articles

6/29/2020
Ermolenko DN, Mathews DH. "Making ends meet: New functions of mRNA secondary structure." Wiley interdisciplinary reviews. RNA.. 2020 Jun 29; :e1611. Epub 2020 Jun 29.

6/13/2020
Wakabayashi H, Warnasooriya C, Ermolenko DN. "Extending the Spacing between the Shine-Dalgarno Sequence and P-Site Codon Reduces the Rate of mRNA Translocation." Journal of molecular biology.. 2020 Jun 13; Epub 2020 Jun 13.

6/4/2020
Warnasooriya C, Feeney CF, Laird KM, Ermolenko DN, Kielkopf CL. "A splice site-sensing conformational switch in U2AF2 is modulated by U2AF1 and its recurrent myelodysplasia-associated mutation." Nucleic acids research.. 2020 Jun 4; 48(10):5695-5709.

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