CONTACT INFORMATIONBIOGRAPHYCREDENTIALSAWARDSPUBLICATIONSJesse B. Schallek, Ph.D.Contact InformationPhone NumbersOffice: (585) 273-4848Research LabsSchallek Lab- Flaum Eye InstituteVisit Schallek Lab- Flaum Eye Institute Lab WebsiteLocationsUniversity of Rochester Medical CenterSchool of Medicine and Dentistry601 Elmwood Ave, Box 659Rochester, NY 14642Additional LinksSchallek Lab- ARIAFaculty AppointmentsAssistant Professor - Department of Ophthalmology (SMD) Assistant Professor - Center for Visual Science A&S (RC) - JointAssistant Professor - Department of Neuroscience (SMD) - JointBiographyMy laboratory invents new tools to evaluate eye health by measuring function. We are developing cutting-edge cameras to view the cells of the living eye with microscope resolution. In this way, we can study retinal health and disease within single cells of the retina without ever requiring a biopsy.Professional BackgroundDr. Jesse Schallek is assistant professor of ophthalmology at the Flaum Eye Institute at the University of Rochester, NY. He also holds joint appointments in the department of Neuroscience and is a member of the Center for Visual Science. He received his Bachelor’s degree in Bioengineering from Syracuse University and a PhD in Neuroscience from SUNY Upstate Medical University in 2010. His postdoctoral research focused on developing adaptive optics technology at the University of Rochester training with David Williams, PhD. Dr. Schallek’s laboratory develops and deploys new imaging technologies to study single cell blood flow in the living retinae of humans and animal models. By combining high resolution adaptive optics imaging with high frame rate camera capture, a central focus is to better resolve and thus better image mechanisms of blood flow dysfunction noninvasively through the eye. This provides direct benefit to diagnosis and treatment retinal diseases; and may also in the near future, provide insight to whole body systemic health through the optics of the eye. In the early stages of his career, Dr. Schallek has been honored with several awards including: The Dana Foundation- David Mahoney Neuroimaging Award, the Research to Prevent Blindness Career Development Award as well as training awards from the Ruth Kirschstein National Research Service Award (NRSA) and recognition as an Edmund Optics Higher Education Grant Program Finalist. Dr. Schallek holds several patents and provisional filings on his adaptive optics technology and has received spotlight and editors picks designation on his recent papers focused on blood flow determination in the retina. He is grateful for funding by five national competitive research grants to support his research.ResearchOur lab investigates blood flow in the living eye by using a specialized camera called an Adaptive Optics Scanning Light Ophthalmoscope (AOSLO) to correct for small imperfections of the optics of the eye. Once corrected, we can image the microscopic integrity of the smallest vessels that are ten-times thinner than a human hair. Additionally, capturing videos of this tissue enables study of the movement of single blood cells flowing within this network. We are developing and applying this cutting-edge technology to study blood flow in the retina in conditions of health and disease. These advances are critical for studying neural cells that line the back of our eyes are sensitive to light and initiate our ability to see. These cells are among the most metabolically active tissues in the human body and are nourished by a dense network of capillaries that circulate blood to deliver nutrients and remove waste products from these hard-working cells. We use and develop adaptive optics eye cameras to study the dysfunction of this neural-vascular system associates with a variety of retinal diseases and collectively gives rise to the leading cause of blindness in the developed world.CredentialsEducation2003BS | Syracuse UniversityBioengineering2010PhD | SUNY Upstate Medical UniversityNeurosciencePost-doctoral Training & Residency2010 - 2015Adaptive Optics Imaging in the Living Eye- Advisor: David WilliamsAwards2017 - 2019David Mahoney Neuroimaging AwardSponsor: Dana Foundation2016 - 2020Career Development AwardSponsor: Research to Prevent Blindness2016 - 2020Research to Prevent Blindness Career Development AwardSponsor: Research to Prevent Blindness2013 - 2015Ruth Kirschstein National Research Service AwardSponsor: NIH2013Edmund Optics Higher Education Grant Program Finalist2012 - 2012Schmitt Program on Integrative Brain Research PostdoctoralSponsor: Schmitt ProgramLocation: University of Rochester2012 - 2012ARVO Member in Training (MIT) Outstanding Poster AwardSponsor: ARVO2012 - 2012Retina Research Foundation/J.M. and E.C. Lawrence Travel AwardSponsor: Retina Research Foundation2002 - 2002Mabel E. Lewis Summer Research FellowLocation: Syracuse UniversityVIEW ALL expand_morePublicationsJournal Articles10/1/2021Joseph A, Power D, Schallek J. "Imaging the dynamics of individual processes of microglia in the living retina ." Biomedical optics express.. 2021 Oct 1; 12(10):6157-6183. Epub 2021 Sep 10. 10/14/2020Joseph A, Chu CJ, Feng G, Dholakia K, Schallek J. "Label-free imaging of immune cell dynamics in the living retina using adaptive optics." eLife.. 2020 Oct 14; 9Epub 2020 Oct 14. 2/15/2020Schallek JB, Williams DR, Guevara-Torres A. "Origin of cell contrast in offset aperture adaptive optics ophthalmoscopy." Optics letters.. 2020 Feb 15; 45(4):840-843. VIEW ALL PUBLICATIONSClose WindowSchedule an appointment with Jesse B. Schallek, Ph.D.Please answer the following questions to help us find the right appointment for you.Important: If you believe that you have a medical or psychiatric emergency, please call 911 or go to the nearest hospital. This website is not intended for emergency care.Have you seen this provider in the last 2 years?YesNoExisting Patient Schedule or request a follow up appointment online through MyChart. If you do not have a MyChart account, please close this window and call the appointment phone number. Jesse B. Schallek, Ph.D. is currently scheduling for the following appointment type(s): Our policy does not permit patients to establish care with multiple providers within the same practice or specialty without prior approval. If you choose a new provider in the same office, we will cancel the appointment. Please contact the office directly with questions on this policy.