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Schallek Lab

Welcome to the Schallek Lab

The neural cells that line the back of our eyes are sensitive to light and initiate our ability to see. These cells are among the most metabolically active tissues in the human body and are nourished by a dense network of capillaries that circulate blood to deliver nutrients and remove waste products from these hard-working cells. However, dysfunction of this neural-vascular system associates with a variety of retinal diseases and collectively gives rise to the leading cause of blindness in the developed world.

Our lab investigates blood flow in the living eye by using a specialized camera called an Adaptive Optics Scanning Light Ophthalmoscope (AOSLO) to correct for small imperfections of the optics of the eye. Once corrected, we can image the microscopic integrity of the smallest vessels that are ten-times thinner than a human hair. Additionally, capturing videos of this tissue enables study of the movement of single blood cells flowing within this network. We are developing and applying this cutting-edge technology to study blood flow in the retina in conditions of health and disease.

Jesse B. Schallek, Ph.D.

Jesse B. Schallek, Ph.D.

Principal Investigator

Publications

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News

2018
Aby Joseph and Sarah Walters received the ARVO Foundation/Retina Reseach Foundation/Joseph M. and Eula C. Lawrence Travel Grant to the 2018 ARVO Annual Meeting in Honolulu, HI

2017
Congratulations to Aby Joseph, winner of the 2017 Leica Imaging Award for his time-lapse imaging of retinal microglia. Aby was honored with the award at the 2017 Immune Imaging Symposium at the University of Rochester.

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Contact Us

  Schallek Lab
MC G-4113
601 Elmwood Ave
Rochester, NY 14642