Brian Keane, Ph.D.

Contact Information

Faculty Appointments

Assistant Professor - Department of Psychiatry , Research (SMD)
Assistant Professor - Department of Neuroscience (SMD) - Joint
Assistant Professor - Center for Visual Science A&S (RC) - Joint

Biography

Professional Background

Dr. Keane is Assistant Professor of Psychiatry at the University of Rochester Medical Center with additional affiliations in Neuroscience, Brain and Cognitive Science, and Center for Visual Science. He employs behavioral psychophysics and functional neuroimaging to investigate visual object perception – both how it goes right in healthy people and how it becomes disturbed in those with psychosis. Dr. Keane obtained a doctoral degree in Psychology from the University of California in Psychology, a doctoral degree in Analytic Philosophy from Rutgers University, and a Bachelor of Arts Triple Major (Physics & Astronomy, Spanish, Philosophy) from the University of Pittsburgh. Dr. Keane has published over 40 peer reviewed works in clinical and non-clinical outlets and has been the recipient of a number of awards and grants including a K01 Mentored Career Development award, an NRSA postdoctoral fellowship, an ICOSR Young Investigator Award, a UCLA Dissertation Year Fellowship, and an APA Dissertation Research Award.

Research

Dr. Keane investigates how the visual system transforms spatiotemporally fragmented retinal images into discrete representations of objects and how this transformation becomes compromised among those with psychosis. This question is approached with behavioral psychophysics, eye movement analysis, and resting-state and task-based functional MRI. Dr. Keane has co-developed relatively simple visual tasks that can briefly and non-invasively elicit large visual impairments in schizophrenia patients; such impairments are linked to a variety of clinical variables such as conceptual disorganization, premorbid functioning, and illness duration. Over the years, Dr. Keane has also written on foundational questions in cognitive science that are related to object perception, such as conditions under which visual grouping becomes malleable by higher-order thought or the best way to characterize the content of sensory representations.

Credentials

Education

1999
Bachelor of Arts | University of Pittsburgh, PA, University Honors College
Physics & Astronomy, Spanish, Philosophy (intensive)

2006
Doctor of Philosophy | Rutgers University, New Brunswick
Philosophy

2009
Doctor of Philosophy | University of California, Los Angeles
Psychology

Post-doctoral Training & Residency

10/2009 - 10/2011
Postdoctoral Fellow, Rutgers, The State University of New Jersey, Piscataway, NJ, University Behavioral Health Care, Center for Cognitive Science.

Awards

2016
Rutgers/RBHS Travel Award
Sponsor: Rutgers University

2013 - 2016
NIH/NIMH LRP program
Sponsor: NIH/NIMH

2013
Young Investigator Travel Award
Sponsor: International Congress on Schizophrenia Research

2008 - 2009
UCLA Graduate Division Dissertation Year Fellowship
Sponsor: UCLA

2008
American Psychological Association Dissertation Award
Sponsor: American Psychological Association

1999
Summa Cum Laude
Sponsor: University of Pittsburgh

1999
Phi Beta Kappa
Sponsor: University of Pittsburgh

1995 - 1999
University Scholarship
Sponsor: University of Pittsburgh

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Clinical Trials

Psychosis Research Group Future Contact Database

Lead Researcher: Brian Keane

This future contact database will facilitate contact with prospective subjects, giving them greater opportunities to participate in behavioral and neuroimaging studies for which they may be eligible.

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Publications

Journal Articles

8/29/2022
Diamond A, Silverstein SM, Keane BP. "Visual system assessment for predicting a transition to psychosis." Translational psychiatry.. 2022 Aug 29; 12(1):351. Epub 2022 Aug 29.

12/30/2021
Keane BP, Erlikhman G, Serody M, Silverstein SM. "A brief psychometric test reveals robust shape completion deficits in schizophrenia that are less severe in bipolar disorder." Schizophrenia research.. 2021 Dec 30; 240:78-80. Epub 2021 Dec 30.

7/2021
Hearne LJ, Mill RD, Keane BP, Repovš G, Anticevic A, Cole MW. "Activity flow underlying abnormalities in brain activations and cognition in schizophrenia." Science advances.. 2021 Jul; 7(29)Epub 2021 Jul 14.

Books & Chapters

2009
Chapter Title: Visual objects as the referents of early vision: A response to a Theory of Sentience
Book Title: Computation, cognition, and Pylyshyn
Author List: Keane, B. P.
Published By: MIT Press 2009 in Cambridge

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