Dr. Jospe is engaged in clinical research aimed at preventing Type 1 diabetes and studying the underlying autoimmune mechanisms causing Type 1 diabetes mellitus. He is an investigator in “TrialNet,” an international study funded by the NIH and other organizations, investigating the natural history of Type 1 diabetes and possible interventions to prevent diabetes in individuals at high risk. He has partnered locally with the “Autoimmunity Center of Excellence” at the University of Rochester, as well as the Benaroya Research Institute, Virginia Mason Medical Center, Seattle, WA. He has been co-investigator in a multi-center industry sponsored study investigating the utility of continuous glucose sensor technology in the care of children with Type 1 diabetes.
Dr. Weber is a pediatric endocrinologist with a special clinical and research interest in bone health. He is the principal investigator on multiple active clinical studies at URMC designed to better understand the effects of type 1 diabetes on calcium metabolism and bone health. He is a co-investigator on a study using data from the multi-center MDSTARnet registry to investigate the burden of endocrine disease in patients with Duchenne muscular dystrophy. Additionally, he is the site PI for a multi-national registry study to describe the natural history of hypophosphatasia, a rare genetic bone disease. He is also working with research collaborators at The Children’s Hospital of Philadelphia and Stanford University to develop new and improved methods for the assessment of body composition in both pediatric and adult populations.
Dr. Orlowski has been involved in a multi-center industry sponsored study investigating the utility of continuous glucose sensor technology in the care of children with Type 1 diabetes. He is a co-investigator with Dr. Jospe in the TrialNet study.
Dr. Svoren Investigates environmental factors on the development of pancreatic autoimmunity, the immunologic response, and the onset of type 1 diabetes. She is interested in preventing complications and preserving health for pediatric patients with diabetes, including outcomes and translational research activities. She also assesses innovative technologies, like continuous glucose monitoring.