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Nimish A. Mohile, M.D.

(Pronouns: he/him/his)

Contact Information

Phone Numbers

Appointment: (585) 275-5830

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

assignmentAccepting New Patients

Faculty Appointments

Patient Care Settings

Cancer, Neurology

Biography

Dr. Mohile completed his residency training at Northwestern University, followed by a fellowship in Neuro-oncology at Memorial Sloan-Kettering Cancer Center. He is certified in Neurology and Neuro-oncology. In 2007, he joined the neurology department at the University of Rochester where he built and fostered the neuro-oncology division and multi-disciplinary brain tumor program. His mission is to teach, elevate clinical care and perform research that extends and improves the lives of patients with brain tumors.

Dr. Mohile sees patients with primary and metastatic brain tumors and is involved in administering chemotherapy, treating seizures and managing side effects of brain tumors and brain tumor therapy. In addition, he does consultations on patients with neurologic complications of cancer or cancer treatments.

Professional Background

Nimish Mohile, MD, MS, FAAN is a Professor of Neurology and Oncology at the University of Rochester and the Ann Aresty Camhi Professor of Neurology. He serves as the Associate Chair for Academic Affairs, Neuro-oncology Division Chief and leads the Neuro-oncology service line. He is a UCNS fellowship program director, serves on the UCNS Certification committee, chairs the American Society of Clinical Oncology Glioma Guidelines Panel and is currently the Chair of the AAN section for Neuro-oncology.

As an Associate Chair for Academic Affairs, he has spearheaded innovative programs that emphasize personal values, identity and reflective work in the professional development of faculty, administrative staff, advanced practice providers and residents. He also directs departmental leadership programs for residents and faculty to develop leadership skills, implement change and develop resilient teams. At the American Academy of Neurology, he serves as the Physician Lead for the Transforming Leaders Program.

Dr. Mohile aspires to help organizations transform into multicultural, antiracist and equitable entities. He is an advocate for incorporating principles of inclusion, diversity, equity, antiracism and social justice into the profession of neurology. He is the Chair of the AAN Diversity Officer’s Group.

Research

His research focuses on developing and testing therapeutic and supportive care interventions to improve and extend the lives of patients with malignant gliomas. He has authored over 50 peer-reviewed publications. He is currently the principal investigator of several industry-sponsored, investigator-initiated and NCI- funded clinical trials. He has developed a body of work that explores the burdens experienced by patients with brain tumors and caregivers, related to hospitalizations, seizures, decision-making and end of life care.

Credentials

Specialties

    Education

    2000
    MD | St. George's University School of Medicine (Grenada)

    Post-doctoral Training & Residency

    07/01/2005 - 06/30/2007
    Fellowship at Memorial Sloan-Kettering Cancer Center

    07/01/2004 - 06/30/2005
    Fellowship in Clinical Neurophysiology at Northwestern Memorial Hospital

    07/01/2001 - 06/30/2004
    Residency in Neurology at Northwestern Memorial Hospital

    07/01/2000 - 06/30/2001
    Internship in Internal Medicine at Norwalk Hospital

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    Awards

    2015
    A. B. Baker Teacher Recognition Award
    Sponsor: American Academy of Neurology

    2011
    SWOG Travel Award Recipient
    Sponsor: Southwest Oncology Group

    2011
    Neurology Faculty Teaching Award
    Sponsor: University of Rochester
    Location: Rochester, NY

    2009
    American Neurological Association Junior Academic Scholarship Award

    2007
    American Society of Clinical Oncology Foundation Merit Award
    Sponsor: American Society of Clinical Oncology Foundation

    2004
    Graduate Medical Education Award for excellence in teaching medical students

    2004
    AAN Resident Annual Meeting Scholarship
    Sponsor: American Academy of Neurology

    1996 - 2000
    Dean's List
    Sponsor: St George's University
    Location: Grenada, WI

    1994
    Dean's List
    Sponsor: Duke University
    Location: Durham, NC

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    Clinical Trials

    EF-32: Pivotal, Randomized, Open-Label Study of Optune® (Tumor Treating Fields, 200kHz) Concomitant With Radiation Therapy and Temozolomide for the Treatment of Newly Diagnosed Glioblastoma

    Lead Researcher: Nimish A Mohile

    To test the effectiveness and safety of Optune® given concomitantly with radiation therapy (RT) and temozolomide (TMZ) in newly diagnosed GBM patients, compared to radiation therapy and temozolomide alone. In both arms, Optune® and maintenance temozolomide are continued following radiation therapy.

    View Study Details

    Genomically-Guided Treatment Trial in Brain Metastases

    Lead Researcher: Nimish A Mohile

    This phase II trial studies how well genetic testing works in guiding treatment for patients with solid tumors that have spread to the brain. Several genes have been found to be altered or mutated in brain metastases such as NTRK, ROS1, CDK, PI3K, or KRAS G12C. Medications that target these genes such as abemaciclib, paxalisib, entrectinib and adagrasib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Genetic testing may help doctors tailor treatment for each mutation.

    View Study Details

    Publications

    Journal Articles

    11/20/2023
    Gewandter JS, Culakova E, Davis JN, Gada U, Guido JJ, Bearden JD, Burnette B, Shah D, Morrow G, Mustian K, Sluka K, Mohile N. "Wireless transcutaneous electric nerve stimulation (TENS) for chronic chemotherapy-induced peripheral neuropathy (CIPN): a proof-of-concept randomized clinical trial." The journal of pain.. 2023 Nov 20; Epub 2023 Nov 20.

    8/15/2023
    Brody DL, Gottesman RF, Griffin G, Khaliq ZM, Lackland DT, Ling G, Mohile N. "Diversity, Equity, Inclusion, and Health Inequities Training in Neurologic Disorders and Stroke: Analysis and Recommendations From the NINDS Advisory Council Working Group." Neurology.. 2023 Aug 15; 101(7 Supplement 1):S59-S66.

    2/15/2023
    Hardy SJ, Finkelstein AJ, Tivarus M, Culakova E, Mohile N, Weber M, Lin E, Zhong J, Usuki K, Schifitto G, Milano M, Janelsins-Benton MC. "Cognitive and neuroimaging outcomes in individuals with benign and low-grade brain tumours receiving radiotherapy: a protocol for a prospective cohort study." BMJ open.. 2023 Feb 15; 13(2):e066458. Epub 2023 Feb 15.

    Books & Chapters

    2007
    Chapter Title: Principles of Chemotherapy
    Book Title: Brain Tumors: Practical Guide to Diagnosis and Treatment
    Author List: Abrey LE and Mohile NA
    Edited By: Baehring J, Piepmeier J
    Published By: Informa Health Care, USA 2007 in New York

    2006
    Chapter Title: Chemotherapy of Neuronal Tumors
    Book Title: Handbook of Brain Tumor Chemotherapy
    Author List: Mohile, N.A.; Raizer, J.J.
    Edited By: Newton, H.B.
    Published By: Elsevier 2006 in Amsterdam: Boston

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