Dr. Saubermann's clinical interest is centered on taking care of adolescents and adults with Inflammatory Bowel Diseases, such as Crohn's Disease, Ulcerative Colitis, Celiac Sprue(gluten sensitive enteropathy), and microscopic /lymphocytic colitis, though he also sees patients with a variety of gastrointestinal and liver related illnesses. As part of the complex care required by these patients, he utilizes a multidisciplinary approach that sometimes involves rheumatologists, pathologists, dermatologists radiologists, ophthalmologist, and surgeons. Through his clinical trial work, he also provided access to advanced treatments that are being tested in the treatment of these disorders.
Dr. Lawrence Saubermann is a Gastroenterologist at Strong Memorial Hospital and Associate Professor of Medicine at the University of Rochester School of Medicine. He received a B.A. in Biology from Brandeis University, Waltham, Massachusetts. He attended medical school at the University of Texas, Southwestern Medical School in Dallas, Texas. He then completed his internship and residency in Internal Medicine at Rhode Island Hospital, and Brown University, in Providence, Rhode Island. Dr. Saubermann then completed a clinical and research fellowship in Gastroenterology at Brigham and Women's Hospital, Harvard Medical School, in Boston, Massachusetts. He was an Instructor in Medicine at the Brigham and Women's hospital for a couple of years before moving to Boston University Medical Center to establish his independent research program. While at Boston University Medical Center, he became an Assistant Professor of Medicine, and stayed there for five years as a Staff Gastroenterologist. In July 2005, he came to Strong Memorial Hospital to continue his research and clinical activities in the area of Inflammatory Bowel Disease. He has received grants and published widely in this area, as well as written chapters in major textbooks. He enjoys teaching on the wards, in the clinics, and in the laboratory.
Dr. Saubermann is interested in the intestinal mucosal immune system, and how it is involved in Inflammatory Bowel Diseases, such as Crohn's Disease, Ulcerative Colitis, Microscopic/lymphocytic colitis, and Celiac Sprue. He has a number of projects related to inflammatory bowel disease, including clinical research trials with new biologic agents, testing for novel serologic markers of disease activity, and examining the effects of environmental toxins on the mucosal immune system. He is collaborating with other clinical and basic science researchers throughout the university to better understand the mechanisms behind the disease and develop new therapies. In addition, he participates as a co-investigator on a longitudinal countywide database study of inflammatory bowel disease subjects.
CCFA Executive Board and CMAC
Location: Rochester Chapter
Fellowship in American College of Gastroenterology
Chair of Education, Appointed Member
Sponsor: CCFA Medical Advisory Committee
Location: Rochester, NY
Senior Research Award
Crohn's and Colitis Foundation of America Senior Research Award
Appointed Institutional Review Board Committee Member (Panel Purple, Active)
Appointed Member of New England CCFA Medical Advisory Committee (Active)
Broad Medical Research Program Award
Appointed Institutional Review Board Committee Member (Panel Green, Active)
Mentored Clinical Scientist Development Award (K08)
National Institutes of Health
Physician Post-Doctoral Research Fellowship Award
Howard Hughes Medical Institute
Mentored Clinical Scientist Development Award K08
Sponsor: National Institute of Health
Astra-Merck Advanced Research Training Award
American Digestive Health Foundation
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Baig A, Avlasevich SL, Torous DK, Bemis JC, Saubermann LJ, Lovell DP, MacGregor JT, Dertinger SD. "Assessment of systemic genetic damage in pediatric inflammatory bowel disease." Environmental and molecular mutagenesis.. 2020 Aug 5; Epub 2020 Aug 05.
Torous DK, Avlasevich SL, Khattab MG, Baig A, Saubermann LJ, Chen Y, Bemis JC, Lovell DP, Walker VE, MacGregor JT, Dertinger SD. "Human blood PIG-A mutation and micronucleated reticulocyte flow cytometric assays: Method optimization and evaluation of intra- and inter-subject variation." Environmental and molecular mutagenesis.. 2020 Jun 22; Epub 2020 Jun 22.
Kirby C, Baig A, Avlasevich SL, Torous DK, Tian S, Singh P, Bemis JC, Saubermann LJ, Dertinger SD. "Dextran sulfate sodium mouse model of inflammatory bowel disease evaluated for systemic genotoxicity via blood micronucleus and Pig-a gene mutation assays." Mutagenesis.. 2020 Mar 27; 35(2):161-167.
Books & Chapters
Chapter Title: Ulcerative Colitis
Book Title: Therapies of Digestive Disorders, second edition
Author List: Saubermann LJ; Farraye FA
Edited By: M.W. Wolfe, et al, Eds.
Published By: Elsevier Publishers 2006
Chapter Title: Inflammatory Bowel Disease
Book Title: Cecil Essentials of Medicine
Author List: Saubermann, LJ and Farraye, FA.
Edited By: Andreoli TE et al.
Published By: W.B. Saunders Company 2003 in Philadelphia
Chapter Title: Immunological Aspects of Gastroenterology
Book Title: Molecular Immunology of Mucosal T Cells
Author List: Saubermann, LJ and Blumberg RS
Published By: Kluwer Academic Press 2000
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