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Archibald S. Perkins, M.D., Ph.D.

Pathology

Contact Information

Phone Numbers

Office: (585) 276-3399

Fax: (585) 756-4468

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

assignmentAccepting New Patients

Research Labs

Cancer research, using mouse models to investigate molecular mechanisms in acute myeloid leukemia and myelodysplastic syndrome, with focus on the function of the zinc finger oncoprotein EVI1.

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Faculty Appointments

Biography

Dr. Perkins is an active participant in the clinical hematopathology service as well as a researcher exploring the genes that impact the development of leukemias and other human malignancies. His primary focus is acute myeloid leukemia (AML), a particularly lethal type of cancer with no effective therapies at present. His clinical responsibilities include interpretation of bone marrow biopsies and smears, lymph node biopsies, and spleen; and laboratory analyses of coagulation disorders and hemoglobinopathies.

Professional Background

Dr. Perkins is an active participant in the clinical hematopathology service as well as a researcher exploring the genes that impact the development of leukemias and other human malignancies. His primary focus is acute myeloid leukemia (AML), a particularly lethal type of cancer with no effective therapies at present.

Research

Dr. Perkins' current research focus is on Evi1, a complex locus that plays a critical role in both normal Hematopoiesis and myeloid leukemogenesis. Evidence indicates that Evi1 is an important player in maintenance of the leukemic stem cell compartment by increasing proliferation and prolonging survival, in part throu