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Roberto Hernandez-Alejandro, M.D.

Organ Transplant, Surgery

Clinical Interests

Transplant, Liver, Kidney

Contact Information

Phone Numbers

Appointment: (585) 275-5875

Fax: (585) 271-7929

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

assignmentAccepting New Patients


Professional Background

Dr. Roberto Hernandez-Alejandro was the former Director of Liver Transplantation at Western University, Canada and an Associate Professor of Surgery and Oncology.
Dr. Hernandez-Alejandro completed an abdominal transplant and hepato-pancreato-biliary (HPB) surgery fellowship from 2006-2008 at Western University, Canada. Subsequently, he received further training in live donor liver transplantation at the Kyoto University in Japan.
Over the past 8 years, Dr. Hernandez-Alejandro's reputation for leadership and collaboration has helped to build one of the largest Transplant and Hepatobiliary Programs in Canada and is recognized in the broader surgical community nationally and internationally. He is a pioneer in liver resections for malignancy as well as Donation After Cardiac Death (DCD) Liver Transplantation.
His research endeavors are primarily focused on liver regeneration and donation after cardiac death.
Dr. Hernandez-Alejandro has developed several protocols, as the principal investigator, in liver metastasis designed to improve the outcome in DCD's. A pioneer in North America with the ALPPS procedure in the management of liver metastases, Dr. Hernandez-Alejandro is frequently invited by national and international academic centers to give guest lectures on the topic. He has more than 50 peer reviewed publications in the area of HPB and liver transplant.


Faculty Appointments


  • Surgery - American Board of Surgery


MD | Mexico - Universidad la Salle Mexico City

Post-doctoral Training & Residency

07/01/2006 - 06/30/2008
Fellowship in Transplant Surgery at London Health Sciences Center

08/01/2003 - 07/31/2005
Fellowship in Transplant Surgery at Alberta Health Services

03/01/1997 - 02/28/2001
Residency in General Surgery at Mexican Institute of Social Security

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Latin American Leadership Award
Sponsor: Government of Ontario
Location: London North Center

Excellence in Academics
Sponsor: Department of Oncology, Western University
Location: London, Ontario, Canada

President's Award for Innovation
Sponsor: London Health Science Center
Location: London, Ontario, Canada

Mentor for Rising Star Award
Sponsor: International Liver Transplantation Society
Location: Sydney, Austraila

Best Clinical Abstract at CST 2013
Sponsor: Clinical Society of Transplantation
Location: Lake Louise, Alberta, Canada

Clinical Abstract Award Winner
Sponsor: Clinical Society of Transplantation
Location: Quebec City, QC, Canada

Resident Mentor Award
Sponsor: Western University
Location: London, Ontario, Canada

2010 - 2011
USC Teaching Honour Roll Award of Excellence
Sponsor: University of Western Ontario
Location: London, Ontario, Canada

Clerkship Teacher of the Year Award
Sponsor: Department of Surgery, Western University
Location: London, Ontario, Canada

Distinguished Fellow for Outstanding Research in the Field of Transplantation
Sponsor: American Society of Transplantation
Location: SanDiego, CA, USA

Rising Star Award
Sponsor: 2008 Joint International Congress
Location: Paris, France

Clinical Abstract Award Winner
Sponsor: Clinical Society of Transplantation
Location: Banff, Alberta, Canada

Clinical Abstract Award Winner
Sponsor: Canadian Society of Transplantation
Location: Mont-Tremblant, Quebec

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Journal Articles

Al Hasan I, Tun-Abraham ME, Wanis KN, Garcia-Ochoa C, Levstik MA, Al-Judaibi B, Hernandez-Alejandro R. "Optimizing associated liver partition and portal vein ligation for staged hepatectomy outcomes: Surgical experience or appropriate patient selection?" Canadian journal of surgery. Journal canadien de chirurgie.. 2017 Dec 0; 60(6):408-415.

Pineda-Solís K, Paskar D, Tun-Abraham M, Hernandez-Alejandro R. "Expanding the limits of resectability: Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) using monosegment 6, facilitated by an inferior right hepatic vein." Journal of surgical oncology.. 2017 Jun 0; 115(8):959-962. Epub 2017 Mar 07.

Shaler CR, Choi J, Rudak PT, Memarnejadian A, Szabo PA, Tun-Abraham ME, Rossjohn J, Corbett AJ, McCluskey J, McCormick JK, Lantz O, Hernandez-Alejandro R, Haeryfar SMM. "MAIT cells launch a rapid, robust and distinct hyperinflammatory response to bacterial superantigens and quickly acquire an anergic phenotype that impedes their cognate antimicrobial function: Defining a novel mechanism of superantigen-induced immunopathology and immunosuppression." PLoS biology.. 2017 Jun 0; 15(6):e2001930. Epub 2017 Jun 20.

Books & Chapters

Chapter Title: Liver and Kidney Donation following Cardiac Death
Book Title: Operative Techniques in Transplant Surgery
Author List: Hernandez-Alejandro R
Edited By: Michael Englesbe
Published By: Lippincott Williams & Wilkins2014 in Philadelphia, PA