28th Annual Genetics Day This year's Genetics Day provided another opportunity to celebrate the impact ofGenetics on science and medicine. An excellent selection of speakers from the University of Rochester Medical Center highlighted highlighted the importance of diverse genetic mechanisms ranging from chromatin remodeling in erythropoesis (Laurie Steiner) and DNA damage repair (Xi Bin) to translational control by riboswitches (Jow Wedekind) and di-codon usage (Elizbeth Grayhack). Genetics Day concluded with the Fred Sherman lecture by Dr. Michael Levine (Princeton University). His presentation on visualizing the mechanisms of transcriptional enhancers was equally entertaining and insightful. Originally from the Hollywood area, and by his own admission a closet movie producer, Dr. Levine wowed audiences with in vivo movies of enhancer reporters, shedding new light on what we all thought was an established principle of molecular genetics. Congratulations to the 2016 Genetics Day Poster Session Winners! Graduate students: Manisha Taya – Hammes Lab The Role of Estrogen Signaling in a Mouse Model for Lymphangioleiomyomatosis (Lam) Sam Carrell – Thornton Lab Silencing of Myotonic Dystrophy Protein Kinase (Dmpk) Does Not Affect Cardiac or Muscle Function In Mice Post Docs: Walter Knight – Yan Lab The Role and Mechanism of Cyclic Nucleotide Phosphodiesterase 1c in Regulating Pathological Cardiac Remodeling and Dysfunction Vincent Martinson – Jaenike lab Gut Microbiota of Distantly Related Drosophila Species Share Similar Bacterial Diversity Genetics Day has been a long standing tradition at the University of Rochester And more recently includes the Fred Sherman lecture in memory of Fred Sherman a renowned biochemist and geneticist, who led international efforts to establish the yeast Saccharomyces cerevisiae as the premier genetic eukaryotic model system. The lecture is made possible by a generous fund endowed by Fred Sherman's wife, Elena Rustchenko-Bulgac, herself a research professor at the URMC.