Postdoc Jobs at URMC

Amanda Augustin

Postdoc fellow for an NIH-funded study of late-stage erythropoiesis.

The focus of the lab is to investigate the mechanisms behind the dramatic condensation of chromatin that occurs during erythropoiesis, prior to enucleation. Evidence from our group and others suggests that this involves the activation of pathways that are otherwise limited to apoptotic cells.

The project therefore involves studies of chromatin structure, gene expression, post-translational modifications of histones and other proteins, erythroid differentiation and apoptotic processes, and has relevance to disorders that result in anemia, including myelodysplastic syndromes (MDS).

Full Postdoctoral Position Description

Dr. Maiken Nedergaard

and Dr. Lauren Hablitz

Postdoc/Asst Prof – The Glymphatic System, Brain Clearance and Neuroglia under physiological conditions and in disease models.

The Center for Translational Neuromedicine at the University of Rochester invites applications for postdoctoral research associates and/or junior faculty positions in neuroscience to join the laboratory of Maiken Nedergaard, to study the glymphatic system and neuroglia signaling under physiological conditions and in disease models.

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Dr. Gail Johnson

An NIH-funded postdoctoral position is available in the laboratory of Dr. Gail V. W. Johnson in the Department of Anesthesiology and Perioperative Medicine.
 

The overall focus of the lab is on the molecular mechanisms of neurodegeneration with an emphasis on Alzheimer’s disease and central nervous system (CNS) injury. The current project is on elucidating the regulation of vacuolar mediated degradative processes in neurons that mediate tau clearance and how these processes are altered during aging. Individuals who are passionate about research, enjoy exploring new areas of investigation and have a background in molecular and cellular studies are encouraged to apply. A background in molecular neurobiology and experience with primary neuronal cultures is preferred. 

Full Postdoctoral Position Description

Dr. Ed Freedman

The Cognitive Neurophysiology Laboratory (CNL) directed by Dr. John Foxe and co-directed by Dr. Ed Freedman is hiring post-doctoral fellows specializing in the human and/or murine neurophysiology.

The CNL at Rochester is a large lab with a wide-ranging program of research including, but not limited to mouse models of neurodevelopmental disorders, human electrocorticography, stationary and mobile human electroencephalography, and both structural and functional MRI. In addition to basic neurophysiology, current and future projects will involve the study of processing impairments associated with such diseases as schizophrenia, autism, Rett Syndrome,  Alzheimer's disease and other neurologic disorders and diseases.

Full Postdoctoral Position Description

Dr. David MacLean

An NIH-funded postdoctoral position is immediately available in the MacLean lab in the Department of Pharmacology and Physiology at the University of Rochester, NY.

We seek an enthusiastic and motivated researcher to join our team to study the biophysics of glutamate receptors and acid-sensing ion channels. Research will be focused on understanding essential mechanisms of channel activation and desensitization and how these processes can be modulated. Our work combines patch clamp electrophysiology with fast perfusion, non-canonical amino acid incorporation, mathematical modelling and fluorescence spectroscopy approaches.

Full Postdoctoral Position Description

Dr. Douglas Anderson

A postdoctoral position in the laboratory of Dr. Douglas M. Anderson in the Cardiovascular Research Institute and Center for RNA Biology is available to develop novel RNA and DNA targeting technologies, such as CRISPR-Cas systems, to investigate the molecular mechanisms underlying cardiovascular biology and as potential therapeutics for treating cardiovascular disease.

Candidates should have recently earned a Ph.D. or MD/Ph.D degree(s). Expertise in cell and molecular biology is required, and experience with mouse handling a plus. Interested applicants should send curriculum vitae, a brief description of research interests, and contact information of three references to Dr. Douglas Anderson at: Doug_Anderson@urmc.rochester.edu

Liz Leverenz

A Post-Doctoral Position is open in the Maquat Lab at the University of Rochester Medical Center in Rochester, NY. Applicants should hold a PhD or MD/PhD degree(s) and have expertise in molecular, cellular, or structural biology to study one of a number of ongoing projects, including but not limited to FMRP function in Fragile X Syndrome (FXS), or effectors of nonsense-mediated mRNA decay efficiency.

A background in neurobiology and/or stem-cell biology would facilitate the work on FXS (see, e.g., https://www.nature.com/articles/s41556-020-00618-1), and a background in computational biology would facilitate both projects, but neither is required.

Full Postdoctoral Position Description

NIH-funded postdoctoral position is available in the laboratory of Dr. Eric M. Small at the University of Rochester to study molecular mechanisms of fibroblast phenotypic plasticity and pathological cardiac fibrosis. Candidates should have recently earned a Ph.D. or MD/Ph.D degree(s). Expertise in cell/molecular biology is required.

Experience with animal models of disease, mass spectrometry, and computational biology will be a plus. Interested applicants should send curriculum vitae, a brief description of research interests, and the contact information of three references to Dr. Eric Small at Eric_Small@urmc.rochester.edu. 

A postdoctoral position is available in the laboratory of Dr. Jennetta Hammond in the Department of Neurology. The Hammond lab studies neuro-immune interactions essential for proper brain development, as well as, pathways that contribute to CNS autoimmune diseases. These pathways are investigated using a mix of cell and molecular biology techniques, microscopy, and transgenic mouse models.

Current NIH funded projects focus on regulation of the complement pathway in the CNS. Specifically, the lab is characterizing novel complement regulators that are expressed by neurons. These complement inhibitors may serve as protective factors to preserve neurons and neuronal connections during critical windows in brain development when complement is engaged to prune away excess connections.

Disruptions in this process may contribute to the pathogenesis of various neurodevelopmental disorders including autism, schizophrenia, or intellectual disability. These same complement inhibitors may also play a protective role in pathological conditions with heightened inflammation like multiple sclerosis and other CNS autoimmune diseases.

Full Postdoctoral Position Description

A postdoctoral traineeship in Environmental Health (EH) Biostatistics, funded by an NIEHS T32 training grant, is available. We seek applicants with a doctoral degree in (bio)statistics, epidemiology, computational biology, data science, environmental health, or a related field. Depending on statistical training, the appointee may develop and apply novel statistical methodology for projects related to EH, or carry out applied statistical analyses for EH-related projects. The appointee will receive further training in biostatistics and toxicology, and be involved in collaborative work with EH researchers. 

This work will be done under the mentorship of a Biostatistics faculty trainer and co-mentorship from a leading EH researcher. The specific methodological development or area of application may be based in part on the trainee’s interests, and may be motivated by ongoing EH research at UR, such as studies of the effects of exposure to air pollution, metals, endocrine disruptors, pesticides, shale gas (fracking) or stress on pregnancy outcomes, reproduction, immune function, neurodevelopmental disorders, cognitive outcomes, or gene expression pathways. 

Full Postdoctoral Position Description

A Post-Doctoral Position is open in the Murphy Lab in the Department of Biomedical Genetics, at the University of Rochester Medical Center in Rochester, NY.  

Applicants should hold a PhD and have expertise in molecular, cellular, or developmental biology. As a member of the Murphy lab, the postdoc would investigate transcription control using genomics and bioinformatics methods in the context of breast cancer and zebrafish development. 

Full Postdoctoral Position Description

An NIH-funded Postdoctoral Associate position is available to investigate the role of cellular plasticity in the response to injury and in regeneration, using genetically engineered mouse models, in combination with RNA Seq, and 3D in vitro cultures. 

Research in the Ovitt laboratory is focused on regeneration and repair of tissue damage that occurs as a result of radiation therapy. Radiation treatment of head and neck cancer patients results in irreversible loss of salivary gland secretory acinar cells, and permanent dry mouth. Our data have revealed previously unrecognized regenerative capacity in irradiated human and mouse salivary glands, which involves cellular plasticity.

Full Postdoctoral Position Description

Two Postdoctoral Positions Available – RNA modification and its potential clinical applications.

Dr. Yi-Tao Yu's lab in the department of Biochemistry and Biophysics, University of Rochester, New York is looking for two highly motivated postdoctoral associates to work in the area of RNA modification, particularly focusing on targeted mRNA modification and its potential clinical applications.  The candidates should hold a PhD degree and have a strong background in molecular biology and/or cell biology.  Experience with cell culture, gene cloning, RNA detection/quantification, and protein expression/detection are required. Prior experience in RNA biology is preferred.

To apply, please send an email to Dr. Yi-Tao Yu with: a CV, names of three references, and a brief summary of previous research experience and future interests.

A postdoctoral position is immediately available in the Glading lab in the Department of Pharmacology and Physiology at the University of Rochester, NY. We seek an enthusiastic and motivated researcher to join our team to uncover novel mechanisms underlying vascular development and the vascular response to inflammation. Research will be focused on the regulation of endothelial cell-cell adhesion in the context of inflammation and vascular disease, with the goal of defining signaling mechanisms that control vascular morphology and function. Our approach combines the systematic use of biochemistry techniques, molecular cloning, imaging, cell-based assays, intravital microscopy, and genetically modified mouse models of disease.

Full Postdoctoral Position Description

A postdoctoral position is available in the laboratory of Eric Phizicky, Ph.D., Professor in the Department of Biochemistry and Biophysics, Center for RNA Biology, University of Rochester Medical Center, to work in the area of tRNA biology. Research in the lab focuses on the biology of tRNA modifications and tRNA decay pathways in two model organisms: the budding yeast Saccharomyces cerevisiae and the distantly related fission yeast Schizosaccharomyces pombe. The research employs cutting edge techniques in molecular biology, genetics, genomics, and biochemistry to understand problems in tRNA biology.

Full Postdoctoral Position Description

A staff scientist/postdoctoral position available to work in the area of cytogenetics and chromosome biology: Dr. Bin Zhang’s lab in the department of Pathology and Laboratory Medicine, University of Rochester, New York is looking for a highly motivated staff scientist or postdoctoral fellow to study the formation, plasticity and epigenetic inheritance of human centromere, and its potential clinical applications.

Full Postdoctoral Position Description

Gail V.W. Johnson, PhD

A postdoctoral position is available in the Nehrke and Johnson laboratories at the University of Rochester School of Medicine and Dentistry to study how site-specific, Alzheimer’s disease (AD)-relevant posttranslational modifications (PTMs) of tau exert toxic effects through their impact on mitochondrial quality control pathways.

This position is funded through a multi-PI R01 NIH grant. It is expected that the successful applicant will primarily be involved in extending results from the C. elegans model system into mammalian primary neuron systems.  In the future, our studies will also include the use of mouse models to fully understand how tau with AD-relevant PTMs impact mitochondrial function and neuron health in the context of aging.  

Full Postdoctoral Position Description

Dr. Jennifer Gewandter

The University of Rochester Medical Center has an opening for a Post-doctoral Associate to spear-head and contribute to various research projects and publications within the ACTTION public-private partnership with the U.S. Food and Drug Administration (FDA) whose mission is to expedite the discovery and development of analgesic treatments with greater efficacy and safety.

The projects will consist of developing and qualifying through the FDA novel outcome measures to be used in analgesic clinical trials, including a patient-reported outcome measure of pain intensity and a wearable sensor-based activity measure. It will also include drafting and editing manuscripts that report the results of reviews, secondary data analyses, or expert consensus meetings.

Responsibilities will include collaborating closely with the ACTTION leadership and external collaborators to design studies, recruit participants, collect, organize, and analyze qualitative and quantitative data, and ensure timely communication with the FDA when necessary. Responsibilities may also include supervising research assistants.

Full Postdoctoral Position Description

Dr. Omar Aljitawi

A post-doctoral position is available at the University of Rochester Medical Center (URMC) in the laboratory of Dr. Omar Aljitawi . The project is funded by a grant from the US National Institutes of Health/National Cancer Institute and will study the role of erythropoietin receptor signaling on hematopoietic stem cell homing and engraftment. The laboratory uses a broad range of methods that offers the opportunity for training in multiple areas of the research. 

The ideal candidate has a background in biochemistry, physiology, biology, and hematopoietic stem cell homing and engraftment animal studies. Research experience in the hematopoietic stem cell field is preferred. Looking for candidates who are independently motivated with excellent written and oral communication skills. URMC has a 5 year limit on post-doctoral tenure and preference will be given to recent graduates. 

The University of Rochester School of Medicine and Dentistry is located in upstate New York in the small but vibrant city of Rochester. Rochester is a highly livable community with access to world-class outdoor activities and a strong cultural environment without the hassles of big city living. 

Interested applicants should submit (1) a cover letter with (2) a brief summary of research interests, (3) a complete curriculum vitae, and (4) contact information of three references to Omar Aljitawi, MBBS (Omar_aljitawi@urmc.rochester.edu.)

Timeline: Review of applications will begin immediately, and will continue until the position is filled.

The University of Rochester, an Equal Opportunity Employer, has a strong commitment to diversity and actively encourages applications from candidates from groups underrepresented in higher education.

A full-time NIH-funded postdoctoral research fellowship (up to 1 year with the possibility of continuation depends on the availability of funding) is available immediately. The postdoctoral research fellow will assist with analyzing the genetic and epigenetic data as well as developing new methods for multimodality data analysis. 

Full Postdoctoral Position Description

The Department of Neuroscience at the University of Rochester School of Medicine announces a post-doctoral position under the supervision of Drs. Kuan Hong Wang and John Foxe. The successful candidate will participate in a study supported by the National Institutes of Health (NIH). The goal of the study is to take a translational approach to development of reliable neurologic biomarkers for Batten disease and use murine models to investigate the underlying cellular mechanisms. This study is the principal project of the Intellectual & Developmental Disabilities Research Center (IDDRC) at the University of Rochester and funded by the National Institute of Child Health and Human Development (NICHD).

Full Postdoctoral Position Description

We are seeking a motivated postdoctoral associate to work in the field of Hemodialysis The overarching goal is for the candidate to develop miniaturized hemodialysis (HD) subsystems for portable or wearable hemodialysis. The position will be held in the Department of Biomedical Engineering. The main research areas will include: (1) development of a sheet-membrane based dialyzer for large-animal HD; (2) development of a membrane-based plasma generator; (3) benchtop evaluation of the two devices alone and in tandem; (4) conduct large-animal hemodialysis studies. The candidate will also have opportunities to work with researchers in the Department of Nephrology, as well as other microfluidic-related projects within the Department of Biomedical Engineering including point-of-care diagnostic devices.

Full Postdoctoral Position Description

A staff scientist/postdoctoral position available to work in the area of cytogenetics and chromosome biology: Dr. Bin Zhang’s lab in the department of Pathology and Laboratory Medicine, University of Rochester, New York is looking for a highly motivated staff scientist or postdoctoral fellow to study the formation, plasticity and epigenetic inheritance of human centromere, and its potential clinical applications.

Full Postdoctoral Position Description

The University of Rochester Clinical & Translational Science Institute (UR CTSI) is seeking outstanding candidates for a new Population Health Research Postdoctoral Fellowship. The position will begin January 1, 2021 or May/June, 2021 and is fully funded for a one-year period. The goal of this Fellowship is to produce a cadre of interdisciplinary researchers, trained in team science and competency-based skills, who can conceptualize research across the translational continuum from basic research through population health. Fellows will choose one of three research tracks: Electronic Health Record as a Resource for Research; National, Regional and Local Database Analytics; or Population Health Behavior Change.

Full UR CTSI Position Description

A postdoctoral position is available in the Allergy, Immunology and Rheumatology Division of the Department of Medicine at the University of Rochester. We are particularly interested in a postdoctoral candidate with research experience in flow cytometry, molecular biology, and RNA sequencing. The research project will focus on the role of B cells in the autoimmune diseases lupus and rheumatoid arthritis with a focus on the pathways that lead to aberrant B cell activation and promotion of plasma cell differentiation and autoreactive plasma cell survival.

Full Postdoctoral Position Description

A full-time postdoctoral associate position is available in Dr. Peng Yao’s laboratory in Aab Cardiovascular Research Institute at the University of Rochester Medical Center. Research in the Yao laboratory focuses on the roles of RNA-binding proteins and noncoding RNAs in cardiovascular health and disease. We aim to understand how translational regulation of protein synthesis influence cardiac health and disease and provide new insights into discovery of novel therapeutic approaches to treat heart disease. This position represents an opportunity to join a top-rated biomedical research campus. We are looking for candidates with experiences or interest in following areas: cardiac biology, cardiovascular disease, biochemistry and molecular biology, RNA biology, bioinformatic data analysis, and genetic and disease animal models.

Full Postdoctoral Position Description

Several NIH-funded postdoctoral positions are available immediately in Environmental Medicine- in the laboratory of Dr. Irfan Rahman to investigate the cellular and molecular mechanisms of inhaled toxicants/e-cigarettes-mediated cellular senescence and mitochondrial dysfunction in the lungs (fibrosis and COPD) with special emphasis on chromatin remodeling, inflammation, deacetylases, exosomes, oxidative stress, redox signaling, epigenetics, bioinformatics, SIRT1 regulation and molecular clock.

Full Postdoctoral Position Description

The University of Rochester Departments of Biomedical Engineering, Biomedical Genetics, and the Center for Oral Biology are seeking 2 outstanding postdoctoral associates for a highly collaborative project. These positions are available for one year starting as soon as possible and can be renewed for subsequent years based on research progress and the availability of funds.

Responsibilities: The principal focus of these positions will be to work on a collaborative team to develop functional human salivary gland tissue chips. For more than 550,000 patients annually diagnosed with head and neck cancers worldwide, severe loss of salivary gland function (xerostomia) is an unavoidable outcome of radiation therapy. Efforts to study radiosensitivity to discover effective radioprotective and regenerative strategies have been hampered by the inability to culture salivary gland mimetics in vitro, due to loss of secretory acinar cell phenotype. The work will utilize our microbubble (MB) array technology as a highthroughput, modular platform for the tissue chips. The MB platform will be used to develop tissue chips capable of long-term secretory function, exploring a variety of variables including cell seeding density, phenotype, and microenvironmental cues with the end goal of screening FDA-approved drugs to identify effective radioprotective agents and testing them in vivo. The project is supported by NIH 1UH3DE027695 (Benoit, DeLouise, Ovitt mPI).

Full Postdoctoral Position Description

Post-doctoral fellowships are available beginning July 1, 2020 for qualified applicants interested in conducting research in pulmonary diseases and lung biology. The University of Rochester houses a dynamic group of more than 30 researchers studying different aspects of lung diseases in a multi-disciplinary manner, with an established track record of mentorship and career development. Candidates will be supported by the NIH/NHLBI T32 Training Grant Multidisciplinary Training in Pulmonary Research” (T32 HL066988)

Full Postdoctoral Position Description

The University of Rochester Departments of Biomedical Engineering, Biomedical Genetics, and the Center for Oral Biology are seeking 2 outstanding postdoctoral associates for a highly collaborative project. These positions are available for one year starting as soon as possible and can be renewed for subsequent years based on research progress and the availability of funds.

Responsibilities: The principal focus of these positions will be to work on a collaborative team to develop functional human salivary gland tissue chips. For more than 550,000 patients annually diagnosed with head and neck cancers worldwide, severe loss of salivary gland function (xerostomia) is an unavoidable outcome of radiation therapy. Efforts to study radiosensitivity to discover effective radioprotective and regenerative strategies have been hampered by the inability to culture salivary gland mimetics in vitro, due to loss of secretory acinar cell phenotype. The work will utilize our microbubble (MB) array technology as a highthroughput, modular platform for the tissue chips. The MB platform will be used to develop tissue chips capable of long-term secretory function, exploring a variety of variables including cell seeding density, phenotype, and microenvironmental cues with the end goal of screening FDA-approved drugs to identify effective radioprotective agents and testing them in vivo. The project is supported by NIH 1UH3DE027695 (Benoit, DeLouise, Ovitt mPI).

Full Postdoctoral Position Description

A postdoctoral research fellowship (up to 2 years) is available under the direction of Ashkan Ertefaie, PhD (Assistant Professor of Biostatistics, University of Rochester) and Michael Kosorok, PhD (Professor of Biostatistics, University of North Carolina-Chapel Hill) at the University of Rochester. This position is supported by an NIH-funded grant focused on adjusting for partial compliance in sequential decision making. The Fellow will also have access to data from two unprecedented sequential randomized trials stored at the Department of Biostatistics and Computational Biology.

Full Postdoctoral Position Description

A postdoctoral position is available immediately in the laboratory of Yi-Fen Lee, Ph.D., Professor in the Department of Urology, Pathology, and Wilmot Cancer Institute, University of Rochester. Research projects focus on characterizing mechanisms by which tumor derived extracellular vesicles (TEVs) promote field cancerization of bladder and how environmental factors such as smoking cigarettes and E-cigarettes synergistically stimulate the TEVs-induced oncogenic alterations in the recipients in the predisposed fields, and compare oncogenic potency of TEV cargo proteins derived from bladder cancer cells exposed to E-cigarettes and flavored compounds.

Full Postdoctoral Position Description

Dr. Yan Sun’s lab focuses on understanding molecular mechanisms of the generation of defective viral genomes (DVGs). DVGs are a discrete subset of viral products generated during viral infection. They use Respiratory syncytial virus (RSV), a leading cause of respiratory illness in children worldwide, as the model to understand how DVGs are generated during infection and how manipulation of their generation impact infection outcome.

Full Postdoctoral Position Description

Two Postdoctoral Positions Available – RNA modification and its potential clinical applications.

Dr. Yi-Tao Yu's lab in the department of Biochemistry and Biophysics, University of Rochester, New York is looking for two highly motivated postdoctoral associates to work in the area of RNA modification, particularly focusing on targeted mRNA modification and its potential clinical applications. The candidates should hold a PhD degree and have a strong background in molecular biology and/or cell biology. Experience with cell culture, gene cloning, RNA detection/quantification, and protein expression/detection are required. Prior experience in RNA biology is preferred.

To apply, please send an email to Dr. Yi-Tao Yu with a CV, names of three references, and a brief summary of previous research experience and future interests.

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A postdoctoral position is immediately available in the NIH funded lab of Dr. Elaine L. Hill in the Department of Public Health Sciences to study the health consequences of shale gas development. Fields of interest include epidemiology, biostatistics, economics, data science or another health related field. The successful candidate will have skills in analysis of large environmental and health related data sets utilizing statistical programming (e.g., SAS, STATA or R).

Postdoctoral Associate Position Description