Education / Graduate Education / PhD Programs / Toxicology / Faculty & Trainees / Recent Publications Recent Publications Coe GLKrout INMunro-Ehrlich MBeamish CRVorojeikina DColman DRBoyd EJWalk STRand MD Assessing the role of the gut microbiome in methylmercury demethylation and elimination in humans and gnotobiotic mice.; Archives of toxicology. 2023 Jul 01. Beach TAFinkelstein JNChang PY Epithelial Responses in Radiation-Induced Lung Injury (RILI) Allow Chronic Inflammation and Fibrogenesis.; Radiation research; Vol 199(5), pp. 439-451. 2023 May 01. Beach TAFinkelstein JNChang PY Epithelial Responses in Radiation-Induced Lung Injury (RILI) Allow Chronic Inflammation and Fibrogenesis.; Radiation research. 2023 Mar 15. Post CMMyers JRWinans BLawrence BP Postnatal administration of S-adenosylmethionine restores developmental AHR activation-induced deficits in CD8+ T cell function during influenza A virus infection.; Toxicological sciences : an official journal of the Society of Toxicology. 2023 Feb 27. Rudy MJSalois GCubello JNewell RMayer-Proschel M Gestational iron deficiency affects the ratio between interneuron subtypes in the postnatal cerebral cortex in mice.; Development (Cambridge, England). 2023 Feb 20. Nagel DJRackow ARKu WYBell TJSime PJKottmann RM Cell-Type-Specific Effects of the Ovarian Cancer G-Protein Coupled Receptor (OGR1) on Inflammation and Fibrosis; Potential Implications for Idiopathic Pulmonary Fibrosis.; Cells; Vol 11(16). 2022 Aug 16. Bell TJNagel DJWoeller CFKottmann RM Ogerin mediated inhibition of TGF-β(1) induced myofibroblast differentiation is potentiated by acidic pH.; PloS one; Vol 17(7), pp. e0271608. 2022 Jul 28. McCarthy CEDuffney PFNogales APost CMLawrence BPMartinez-Sobrido LThatcher THPhipps RPSime PJ Dung biomass smoke exposure impairs resolution of inflammatory responses to influenza infection.; Toxicology and applied pharmacology. 2022 Jul 08. Reed JMSpinelli PFalcone SHe MGoeke CMSusiarjo M Evaluating the Effects of BPA and TBBPA Exposure on Pregnancy Loss and Maternal-Fetal Immune Cells in Mice.; Environmental health perspectives; Vol 130(3). 2022 Mar. Kalininskiy ARackow ARNagel DCroft DMcGrane-Minton HKottmann RM Association between weight loss and mortality in idiopathic pulmonary fibrosis.; Respiratory research; Vol 23(1), pp. 377. 2022 Jan 24. McGuire CCRobert JR Environmental endocrine disruptors and amphibian immunity: A bridge between the thyroid hormone axis and T cell development.; Developmental and comparative immunology. 2022 Jan 15. Rackow ARNagel DJZapas GClough RSSime PJKottmann RM The Novel Small Molecule BTB Inhibits Pro-Fibrotic Fibroblast Behavior though Inhibition of RhoA Activity.; International journal of molecular sciences; Vol 23(19). 2022 Jan 08. McGuire CCRobert JR Developmental exposure to thyroid disrupting chemical mixtures alters metamorphosis and post-metamorphic thymocyte differentiation.; Current research in toxicology; Vol 3, pp. 100094. 2022 Jan 07. Rackow ARJudge JLWoller CFSime PJKottmann RM miR-338-3p Blocks TGFβ-Induced Myofibroblast Differentiation through the Induction of PTEN.; American journal of physiology. Lung cellular and molecular physiology. 2022 Jan 05. Beamish CRLove TMRand MD Developmental Toxicology of Metal Mixtures in Drosophila: Unique Properties of Potency and Interactions of Mercury Isoforms.; International journal of molecular sciences; Vol 22(22). 2021 Nov 09. DiMauro ASeger CMinor BAmitrano AMOkeke ITaya MRackow ARKumar DKottman RMBhagavath BHammes SR Prolactin is Expressed in Uterine Leiomyomas and Promotes Signaling and Fibrosis in Myometrial Cells.; Reproductive sciences (Thousand Oaks, Calif.). 2021 Nov 01. Peppriell AEGunderson JTKrout INVorojeikina DRand MD Latent effects of early-life methylmercury exposure on motor function in Drosophila.; Neurotoxicology and teratology. 2021 Oct 14. Gunderson JTPeppriell AEKrout INVorojeikina DRand MD Neuroligin-1 is a mediator of methylmercury neuromuscular toxicity.; Toxicological sciences : an official journal of the Society of Toxicology. 2021 Sep 21. Herr DJew KWong CKennell AGelein RChalupa DRaab AOberdörster GOlschowka JO'Banion MKElder A Effects of concentrated ambient ultrafine particulate matter on hallmarks of Alzheimer's disease in the 3xTgAD mouse model.; Neurotoxicology. 2021 Mar 29. Fields AMWelle KHo ESMesaros CSusiarjo M Vitamin B6 deficiency disrupts serotonin signaling in pancreatic islets and induces gestational diabetes in mice.; Communications biology; Vol 4(1). 2021 Mar 26. McGuire CCLawrence BPRobert J Thyroid Disrupting Chemicals in mixture Perturb Thymocyte Differentiation in Xenopus laevis tadpoles.; Toxicological sciences : an official journal of the Society of Toxicology. 2021 Mar 03. Burke CGMyers JRPost CMBoulé LALawrence BP DNA Methylation Patterns in CD4+ T Cells of Naïve and Influenza A Virus-Infected Mice Developmentally Exposed to an Aryl Hydrocarbon Receptor Ligand.; Environmental health perspectives; Vol 129(1). 2021 Jan. Anderson TMerrill AKEckard MLMarvin EConrad KWelle KOberdörster GSobolewski MCory-Slechta DA Paraquat Inhalation, a Translationally Relevant Route of Exposure: Disposition to the Brain and Male-Specific Olfactory Impairment in Mice.; Toxicological sciences : an official journal of the Society of Toxicology. 2020 Dec 29. Smyth TVeazey JEliseeva SChalupa DElder AGeoras SN Diesel exhaust particle exposure reduces expression of the epithelial tight junction protein Tricellulin.; Particle and fibre toxicology; Vol 17(1). 2020 Oct 15. Rackow ARNagel DJMcCarthy CJudge JLacy SFreeberg MATThatcher THKottmann RMSime PJ The Self-fulfilling Prophecy of Pulmonary Fibrosis: A Selective Inspection of Pathologic Signaling Loops.; The European respiratory journal. 2020 Sep 17. Gunderson JTPeppriell AEVorojeikina DRand MD Tissue-specific Nrf2 signaling protects against methylmercury toxicity in Drosophila neuromuscular development.; Archives of toxicology. 2020 Aug 20. Peppriell AEGunderson JTVorojeikina DRand MD Methylmercury myotoxicity targets formation of the myotendinous junction.; Toxicology. 2020 Aug 12. Phelan-Dickinson SJPalmer BCChen YDeLouise LA The UVR Filter Octinoxate Modulates Aryl Hydrocarbon Receptor Signaling in Keratinocytes via Inhibition of CYP1A1 and CYP1B1.; Toxicological sciences : an official journal of the Society of Toxicology. 2020 Jun 30. Sobolewski MAbston KConrad KMarvin EHarvey KSusiarjo MCory-Slechta DA Lineage- and Sex-Dependent Behavioral and Biochemical Transgenerational Consequences of Developmental Exposure to Lead, Prenatal Stress, and Combined Lead and Prenatal Stress in Mice.; Environmental health perspectives; Vol 128(2). 2020 Feb. Duffney PFEmbong AKMcGuire CCThatcher THPhipps RPSime PJ Cigarette smoke increases susceptibility to infection in lung epithelial cells by upregulating caveolin-dependent endocytosis.; PloS one; Vol 15(5). 2020. Veazey JMEliseeva SIHillman SEStiles KSmyth TRMorrissey CETillotson EJTopham DJChapman TJGeoras SN Inhibiting Protein Kinase D Promotes Airway Epithelial Barrier Integrity in Mouse Models of Influenza A Virus Infection.; Frontiers in immunology; Vol 11. 2020. Palmer BCDeLouise LA Morphology-dependent titanium dioxide nanoparticle-induced keratinocyte toxicity and exacerbation of allergic contact dermatitis.; HSOA journal of toxicology : current research; Vol 4(1). 2020. Jew KHerr DWong CKennell AMorris-Schaffer KOberdörster GO'Banion MKCory-Slechta DAElder A Selective memory and behavioral alterations after ambient ultrafine particulate matter exposure in aged 3xTgAD Alzheimer's disease mice.; Particle and fibre toxicology; Vol 16(1). 2019 Nov 26. Post CMBoule LABurke CGO'Dell CTWinans BLawrence BP The Ancestral Environment Shapes Antiviral CD8+ T cell Responses across Generations.; iScience; Vol 20. 2019 Sep 14. Burke CGMyers JRBoule LAPost CMBrookes PSLawrence BP Early life exposures shape the CD4+ T cell transcriptome, influencing proliferation, differentiation, and mitochondrial dynamics later in life.; Scientific reports; Vol 9(1). 2019 Aug 07. Robert JMcGuire CCNagel SLawrence BPAndino FJ Developmental exposure to chemicals associated with unconventional oil and gas extraction alters immune homeostasis and viral immunity of the amphibian Xenopus.; The Science of the total environment; Vol 671. 2019 Mar 26. Palmer BCJatana SPhelan-Dickinson SJDeLouise LA Amorphous silicon dioxide nanoparticles modulate immune responses in a model of allergic contact dermatitis.; Scientific reports; Vol 9(1). 2019 Mar 25. Morris-Schaffer KMerrill AJew KWong CConrad KHarvey KMarvin ESobolewski MOberdörster GElder ACory-Slechta DA Effects of neonatal inhalation exposure to ultrafine carbon particles on pathology and behavioral outcomes in C57BL/6J mice.; Particle and fibre toxicology; Vol 16(1). 2019 Feb 18. Palmer BCPhelan-Dickenson SJDeLouise LA Multi-walled carbon nanotube oxidation dependent keratinocyte cytotoxicity and skin inflammation.; Particle and fibre toxicology; Vol 16(1). 2019 Jan 08. Morris-Schaffer KMerrill AKWong CJew KSobolewski MCory-Slechta DA Limited developmental neurotoxicity from neonatal inhalation exposure to diesel exhaust particles in C57BL/6 mice.; Particle and fibre toxicology; Vol 16(1). 2019 Jan 07. Veazey JMChapman TJSmyth TRHillman SEEliseeva SIGeoras SN Distinct roles for MDA5 and TLR3 in the acute response to inhaled double-stranded RNA.; PloS one; Vol 14(5). 2019. Rand MDVorojeikina DPeppriell AGunderson JPrince LM Drosophotoxicology: Elucidating Kinetic and Dynamic Pathways of Methylmercury Toxicity in a Drosophila Model.; Frontiers in genetics; Vol 10. 2019. Klocke CSherina VGraham UMGunderson JAllen JLSobolewski MBlum JLZelikoff JTCory-Slechta DA Enhanced cerebellar myelination with concomitant iron elevation and ultrastructural irregularities following prenatal exposure to ambient particulate matter in the mouse.; Inhalation toxicology. 2018 Dec 20. Georas SRansom NHillman SEliseeva SVeazey JSmyth TLe KMeddings J The leaky lung test: A pilot study using inhaled mannitol to measure airway barrier function in asthma.; The Journal of asthma : official journal of the Association for the Care of Asthma. 2018 Nov 16. Spinelli PLatchney SEReed JMFields ABaier BSLu XMcCall MNMurphy SPMak WSusiarjo M Identification of the novel Ido1 imprinted locus and its potential epigenetic role in pregnancy loss.; Human molecular genetics. 2018 Nov 07. Beach TAGroves AMWilliams JPFinkelstein JN Modeling radiation-induced lung injury: lessons learned from whole thorax irradiation.; International journal of radiation biology. 2018 Oct 25. Morris-Schaffer KSobolewski MWelle KConrad KYee MO'Reilly MACory-Slechta DA Cognitive flexibility deficits in male mice exposed to neonatal hyperoxia followed by concentrated ambient ultrafine particles.; Neurotoxicology and teratology. 2018 Oct 11. Beach TAGroves AMJohnston CJWilliams JPFinkelstein JN Recurrent DNA damage is associated with persistent injury in progressive radiation-induced pulmonary fibrosis.; International journal of radiation biology. 2018 Sep 21. Sobolewski MAnderson TConrad KMarvin EKlocke CMorris-Schaffer KAllen JLCory-Slechta DA Developmental Exposures to Ultrafine Particle Air Pollution Reduces Early Testosterone Levels and Adult Male Social Novelty Preference: Risk for Children's Sex-Biased Neurobehavioral Disorders.; Neurotoxicology. 2018 Aug 22. Robert JMcGuire CCKim FNagel SCPrice SJLawrence BPDe Jesús Andino F Water contaminants associated with unconventional oil and gas extraction cause immunotoxicity to amphibian tadpoles.; Toxicological sciences : an official journal of the Society of Toxicology. 2018 Jul 11. Duffney PFFalsetta MLRackow ARThatcher THPhipps RPSime PJ Key roles for lipid mediators in the adaptive immune response.; The Journal of clinical investigation; Vol 128(7). 2018 Jul 02. Morris-Schaffer KSobolewski MAllen JLMarvin EYee MArora MO'Reilly MACory-Slechta DA Effect of neonatal hyperoxia followed by concentrated ambient ultrafine particle exposure on cumulative learning in C57Bl/6J mice.; Neurotoxicology. 2018 Jun 16. Latchney SEFields AMSusiarjo M Linking inter-individual variability to endocrine disruptors: insights for epigenetic inheritance.; Mammalian genome : official journal of the International Mammalian Genome Society; Vol 29(1-2). 2018 Feb. Judge JLNagel DJOwens KMRackow APhipps RPSime PJKottmann RM Prevention and treatment of bleomycin-induced pulmonary fibrosis with the lactate dehydrogenase inhibitor gossypol.; PloS one; Vol 13(5). 2018. Stowell RDWong ELBatchelor HNMendes MSLamantia CEWhitelaw BSMajewska AK Cerebellar microglia are dynamically unique and survey Purkinje neurons in vivo.; Developmental neurobiology. 2017 Dec 29. Prince LMRand MD Methylmercury exposure causes a persistent inhibition of myogenin expression and C2C12 myoblast differentiation.; Toxicology. 2017 Nov 02. Wong ELLutz NMHogan VALamantia CEMcMurray HRMyers JRAshton JMMajewska AK Developmental alcohol exposure impairs synaptic plasticity without overtly altering microglial function in mouse visual cortex.; Brain, behavior, and immunity. 2017 Sep 13. Resseguie EABrookes PSO'Reilly MA SMG-1 kinase attenuates mitochondrial ROS production but not cell respiration deficits during hyperoxia.; Experimental lung research. 2017 Jul 27. Jatana SPalmer BCPhelan SJDeLouise LA Immunomodulatory Effects of Nanoparticles on Skin Allergy.; Scientific reports; Vol 7(1). 2017 Jun 21. Beach TAJohnston CJGroves AMWilliams JPFinkelstein JN Radiation induced pulmonary fibrosis as a model of progressive fibrosis: Contributions of DNA damage, inflammatory response and cellular senescence genes.; Experimental lung research. 2017 May 23. Judge JLLacy SHKu WYOwens KMHernady EThatcher THWilliams JPPhipps RPSime PJKottmann RM The Lactate Dehydrogenase Inhibitor Gossypol Inhibits Radiation-Induced Pulmonary Fibrosis.; Radiation research. 2017 May 02. Jatana SPalmer BCPhelan SJGelein RDeLouise LA In vivo quantification of quantum dot systemic transport in C57BL/6 hairless mice following skin application post-ultraviolet radiation.; Particle and fibre toxicology; Vol 14(1). 2017 Apr 14. Prince LMRand MD Notch Target Gene E(spl)mδ Is a Mediator of Methylmercury-Induced Myotoxicity in Drosophila.; Frontiers in genetics; Vol 8. 2017. Beier EESheu TJResseguie EATakahata MAwad HACory-Slechta DAPuzas JE Sclerostin activity plays a key role in the negative effect of glucocorticoid signaling on osteoblast function in mice.; Bone research; Vol 5. 2017. Wong ELStowell RDMajewska AK What the Spectrum of Microglial Functions Can Teach us About Fetal Alcohol Spectrum Disorder.; Frontiers in synaptic neuroscience; Vol 9. 2017. Palmer BCDeLouise LA Nanoparticle-Enabled Transdermal Drug Delivery Systems for Enhanced Dose Control and Tissue Targeting.; Molecules (Basel, Switzerland); Vol 21(12). 2016 Dec 15. Sobolewski MAllen JLMorris-Schaffer KKlocke CConrad KCory-Slechta DA A novel, ecologically relevant, highly preferred, and non-invasive means of oral substance administration for rodents.; Neurotoxicology and teratology. 2016 Apr 14. Kottmann RMTrawick EJudge JLWahl LAEpa APOwens KMThatcher THPhipps RPSime PJ Pharmacologic inhibition of lactate production prevents myofibroblast differentiation.; American journal of physiology. Lung cellular and molecular physiology; Vol 309(11). 2015 Dec 1. Judge JLOwens KMPollock SJWoeller CFThatcher THWilliams JPPhipps RPSime PJKottmann RM Ionizing radiation induces myofibroblast differentiation via lactate dehydrogenase.; American journal of physiology. Lung cellular and molecular physiology; Vol 309(8). 2015 Oct 15. Lantz CLSipe GOWong ELMajewska AKMedina AE Effects of Developmental Alcohol Exposure on Potentiation and Depression of Visual Cortex Responses.; Alcoholism, clinical and experimental research; Vol 39(8). 2015 Aug. Resseguie EAStaversky RJBrookes PSO'Reilly MA Hyperoxia activates ATM independent from mitochondrial ROS and dysfunction.; Redox biology; Vol 5. 2015 Aug. Winans BNagari AChae MPost CMKo CIPuga AKraus WLLawrence BP Linking the aryl hydrocarbon receptor with altered DNA methylation patterns and developmentally induced aberrant antiviral CD8+ T cell responses.; Journal of immunology (Baltimore, Md. : 1950); Vol 194(9). 2015 May 1. Gerber SACummings RJJudge JLBarlow MLNanduri JJohnson DEPalis JPentland APLord EMRyan JL Interleukin-12 preserves the cutaneous physical and immunological barrier after radiation exposure.; Radiation research; Vol 183(1). 2015 Jan. Prince LKorbas MDavidson PBroberg KRand MD Target organ specific activity of drosophila MRP (ABCC1) moderates developmental toxicity of methylmercury.; Toxicological sciences : an official journal of the Society of Toxicology; Vol 140(2). 2014 Aug 1. Allen JLLiu XWeston DPrince LOberdörster GFinkelstein JNJohnston CJCory-Slechta DA Developmental exposure to concentrated ambient ultrafine particulate matter air pollution in mice results in persistent and sex-dependent behavioral neurotoxicity and glial activation.; Toxicological sciences : an official journal of the Society of Toxicology; Vol 140(1). 2014 Jul. Rand MDMontgomery SLPrince LVorojeikina D Developmental toxicity assays using the Drosophila model.; Current protocols in toxicology / editorial board, Mahin D. Maines (editor-in-chief) ... [et al.]; Vol 59. 2014.