Recent Publications

• 1. Beach TA
  2. Finkelstein JN
  3. Chang PY
  Epithelial Responses in Radiation-Induced Lung Injury (RILI) Allow Chronic Inflammation and Fibrogenesis.; Radiation research. 2023 Mar 15.
• 1. Post CM
  2. Myers JR
  3. Winans B
  4. Lawrence BP
  Postnatal administration of S-adenosylmethionine restores developmental AHR activation-induced deficits in CD8+ T cell function during influenza A virus infection.; Toxicological sciences : an official journal of the Society of Toxicology. 2023 Feb 27.
• 1. Rudy MJ
  2. Salois G
  3. Cubello J
  4. Newell R
  5. Mayer-Proschel M
  Gestational iron deficiency affects the ratio between interneuron subtypes in the postnatal cerebral cortex in mice.; Development (Cambridge, England). 2023 Feb 20.
• 1. Nagel DJ
  2. Rackow AR
  3. Ku WY
  4. Bell TJ
  5. Sime PJ
  6. Kottmann RM
  Cell-Type-Specific Effects of the Ovarian Cancer G-Protein Coupled Receptor (OGR1) on Inflammation and Fibrosis; Potential Implications for Idiopathic Pulmonary Fibrosis.; Cells; Vol 11(16). 2022 Aug 16.
• 1. Bell TJ
  2. Nagel DJ
  3. Woeller CF
  4. Kottmann RM
  Ogerin mediated inhibition of TGF-β(1) induced myofibroblast differentiation is potentiated by acidic pH.; PloS one; Vol 17(7), pp. e0271608. 2022 Jul 28.
• 1. McCarthy CE
  2. Duffney PF
  3. Nogales A
  4. Post CM
  5. Lawrence BP
  6. Martinez-Sobrido L
  7. Thatcher TH
  8. Phipps RP
  9. Sime PJ
  Dung biomass smoke exposure impairs resolution of inflammatory responses to influenza infection.; Toxicology and applied pharmacology. 2022 Jul 08.
• 1. Reed JM
  2. Spinelli P
  3. Falcone S
  4. He M
  5. Goeke CM
  6. Susiarjo M
  Evaluating the Effects of BPA and TBBPA Exposure on Pregnancy Loss and Maternal-Fetal Immune Cells in Mice.; Environmental health perspectives; Vol 130(3). 2022 Mar.
• 1. Kalininskiy A
  2. Rackow AR
  3. Nagel D
  4. Croft D
  5. McGrane-Minton H
  6. Kottmann RM
  Association between weight loss and mortality in idiopathic pulmonary fibrosis.; Respiratory research; Vol 23(1), pp. 377. 2022 Jan 24.
• 1. McGuire CC
  2. Robert JR
  Environmental endocrine disruptors and amphibian immunity: A bridge between the thyroid hormone axis and T cell development.; Developmental and comparative immunology. 2022 Jan 15.
• 1. Rackow AR
  2. Nagel DJ
  3. Zapas G
  4. Clough RS
  5. Sime PJ
  6. Kottmann RM
  The Novel Small Molecule BTB Inhibits Pro-Fibrotic Fibroblast Behavior though Inhibition of RhoA Activity.; International journal of molecular sciences; Vol 23(19). 2022 Jan 08.
• 1. McGuire CC
  2. Robert JR
  Developmental exposure to thyroid disrupting chemical mixtures alters metamorphosis and post-metamorphic thymocyte differentiation.; Current research in toxicology; Vol 3, pp. 100094. 2022 Jan 07.
• 1. Rackow AR
  2. Judge JL
  3. Woller CF
  4. Sime PJ
  5. Kottmann RM
  miR-338-3p Blocks TGFβ-Induced Myofibroblast Differentiation through the Induction of PTEN.; American journal of physiology. Lung cellular and molecular physiology. 2022 Jan 05.
• 1. DiMauro A
  2. Seger C
  3. Minor B
  4. Amitrano AM
  5. Okeke I
  6. Taya M
  7. Rackow AR
  8. Kumar D
  9. Kottman RM
  10. Bhagavath B
  11. Hammes SR
  Prolactin is Expressed in Uterine Leiomyomas and Promotes Signaling and Fibrosis in Myometrial Cells.; Reproductive sciences (Thousand Oaks, Calif.). 2021 Nov 01.
• 1. Peppriell AE
  2. Gunderson JT
  3. Krout IN
  4. Vorojeikina D
  5. Rand MD
  Latent effects of early-life methylmercury exposure on motor function in Drosophila.; Neurotoxicology and teratology. 2021 Oct 14.
• 1. Gunderson JT
  2. Peppriell AE
  3. Krout IN
  4. Vorojeikina D
  5. Rand MD
  Neuroligin-1 is a mediator of methylmercury neuromuscular toxicity.; Toxicological sciences : an official journal of the Society of Toxicology. 2021 Sep 21.
• 1. Herr D
  2. Jew K
  3. Wong C
  4. Kennell A
  5. Gelein R
  6. Chalupa D
  7. Raab A
  8. Oberdörster G
  9. Olschowka J
  10. O'Banion MK
  11. Elder A
  Effects of concentrated ambient ultrafine particulate matter on hallmarks of Alzheimer's disease in the 3xTgAD mouse model.; Neurotoxicology. 2021 Mar 29.
• 1. Fields AM
  2. Welle K
  3. Ho ES
  4. Mesaros C
  5. Susiarjo M
  Vitamin B6 deficiency disrupts serotonin signaling in pancreatic islets and induces gestational diabetes in mice.; Communications biology; Vol 4(1). 2021 Mar 26.
• 1. McGuire CC
  2. Lawrence BP
  3. Robert J
  Thyroid Disrupting Chemicals in mixture Perturb Thymocyte Differentiation in Xenopus laevis tadpoles.; Toxicological sciences : an official journal of the Society of Toxicology. 2021 Mar 03.
• 1. Burke CG
  2. Myers JR
  3. Post CM
  4. Boulé LA
  5. Lawrence BP
  DNA Methylation Patterns in CD4+ T Cells of Naïve and Influenza A Virus-Infected Mice Developmentally Exposed to an Aryl Hydrocarbon Receptor Ligand.; Environmental health perspectives; Vol 129(1). 2021 Jan.
• 1. Anderson T
  2. Merrill AK
  3. Eckard ML
  4. Marvin E
  5. Conrad K
  6. Welle K
  7. Oberdörster G
  8. Sobolewski M
  9. Cory-Slechta DA
  Paraquat Inhalation, a Translationally Relevant Route of Exposure: Disposition to the Brain and Male-Specific Olfactory Impairment in Mice.; Toxicological sciences : an official journal of the Society of Toxicology. 2020 Dec 29.
• 1. Smyth T
  2. Veazey J
  3. Eliseeva S
  4. Chalupa D
  5. Elder A
  6. Georas SN
  Diesel exhaust particle exposure reduces expression of the epithelial tight junction protein Tricellulin.; Particle and fibre toxicology; Vol 17(1). 2020 Oct 15.
• 1. Rackow AR
  2. Nagel DJ
  3. McCarthy C
  4. Judge J
  5. Lacy S
  6. Freeberg MAT
  7. Thatcher TH
  8. Kottmann RM
  9. Sime PJ
  The Self-fulfilling Prophecy of Pulmonary Fibrosis: A Selective Inspection of Pathologic Signaling Loops.; The European respiratory journal. 2020 Sep 17.
• 1. Gunderson JT
  2. Peppriell AE
  3. Vorojeikina D
  4. Rand MD
  Tissue-specific Nrf2 signaling protects against methylmercury toxicity in Drosophila neuromuscular development.; Archives of toxicology. 2020 Aug 20.
• 1. Peppriell AE
  2. Gunderson JT
  3. Vorojeikina D
  4. Rand MD
  Methylmercury myotoxicity targets formation of the myotendinous junction.; Toxicology. 2020 Aug 12.
• 1. Phelan-Dickinson SJ
  2. Palmer BC
  3. Chen Y
  4. DeLouise LA
  The UVR Filter Octinoxate Modulates Aryl Hydrocarbon Receptor Signaling in Keratinocytes via Inhibition of CYP1A1 and CYP1B1.; Toxicological sciences : an official journal of the Society of Toxicology. 2020 Jun 30.
• 1. Sobolewski M
  2. Abston K
  3. Conrad K
  4. Marvin E
  5. Harvey K
  6. Susiarjo M
  7. Cory-Slechta DA
  Lineage- and Sex-Dependent Behavioral and Biochemical Transgenerational Consequences of Developmental Exposure to Lead, Prenatal Stress, and Combined Lead and Prenatal Stress in Mice.; Environmental health perspectives; Vol 128(2). 2020 Feb.
• 1. Duffney PF
  2. Embong AK
  3. McGuire CC
  4. Thatcher TH
  5. Phipps RP
  6. Sime PJ
  Cigarette smoke increases susceptibility to infection in lung epithelial cells by upregulating caveolin-dependent endocytosis.; PloS one; Vol 15(5). 2020.
• 1. Veazey JM
  2. Eliseeva SI
  3. Hillman SE
  4. Stiles K
  5. Smyth TR
  6. Morrissey CE
  7. Tillotson EJ
  8. Topham DJ
  9. Chapman TJ
  10. Georas SN
  Inhibiting Protein Kinase D Promotes Airway Epithelial Barrier Integrity in Mouse Models of Influenza A Virus Infection.; Frontiers in immunology; Vol 11. 2020.
• 1. Palmer BC
  2. DeLouise LA
  Morphology-dependent titanium dioxide nanoparticle-induced keratinocyte toxicity and exacerbation of allergic contact dermatitis.; HSOA journal of toxicology : current research; Vol 4(1). 2020.
• 1. Jew K
  2. Herr D
  3. Wong C
  4. Kennell A
  5. Morris-Schaffer K
  6. Oberdörster G
  7. O'Banion MK
  8. Cory-Slechta DA
  9. Elder A
  Selective memory and behavioral alterations after ambient ultrafine particulate matter exposure in aged 3xTgAD Alzheimer's disease mice.; Particle and fibre toxicology; Vol 16(1). 2019 Nov 26.
• 1. Post CM
  2. Boule LA
  3. Burke CG
  4. O'Dell CT
  5. Winans B
  6. Lawrence BP
  The Ancestral Environment Shapes Antiviral CD8+ T cell Responses across Generations.; iScience; Vol 20. 2019 Sep 14.
• 1. Burke CG
  2. Myers JR
  3. Boule LA
  4. Post CM
  5. Brookes PS
  6. Lawrence BP
  Early life exposures shape the CD4+ T cell transcriptome, influencing proliferation, differentiation, and mitochondrial dynamics later in life.; Scientific reports; Vol 9(1). 2019 Aug 07.
• 1. Robert J
  2. McGuire CC
  3. Nagel S
  4. Lawrence BP
  5. Andino FJ
  Developmental exposure to chemicals associated with unconventional oil and gas extraction alters immune homeostasis and viral immunity of the amphibian Xenopus.; The Science of the total environment; Vol 671. 2019 Mar 26.
• 1. Palmer BC
  2. Jatana S
  3. Phelan-Dickinson SJ
  4. DeLouise LA
  Amorphous silicon dioxide nanoparticles modulate immune responses in a model of allergic contact dermatitis.; Scientific reports; Vol 9(1). 2019 Mar 25.
• 1. Morris-Schaffer K
  2. Merrill A
  3. Jew K
  4. Wong C
  5. Conrad K
  6. Harvey K
  7. Marvin E
  8. Sobolewski M
  9. Oberdörster G
  10. Elder A
  11. Cory-Slechta DA
  Effects of neonatal inhalation exposure to ultrafine carbon particles on pathology and behavioral outcomes in C57BL/6J mice.; Particle and fibre toxicology; Vol 16(1). 2019 Feb 18.
• 1. Palmer BC
  2. Phelan-Dickenson SJ
  3. DeLouise LA
  Multi-walled carbon nanotube oxidation dependent keratinocyte cytotoxicity and skin inflammation.; Particle and fibre toxicology; Vol 16(1). 2019 Jan 08.
• 1. Morris-Schaffer K
  2. Merrill AK
  3. Wong C
  4. Jew K
  5. Sobolewski M
  6. Cory-Slechta DA
  Limited developmental neurotoxicity from neonatal inhalation exposure to diesel exhaust particles in C57BL/6 mice.; Particle and fibre toxicology; Vol 16(1). 2019 Jan 07.
• 1. Veazey JM
  2. Chapman TJ
  3. Smyth TR
  4. Hillman SE
  5. Eliseeva SI
  6. Georas SN
  Distinct roles for MDA5 and TLR3 in the acute response to inhaled double-stranded RNA.; PloS one; Vol 14(5). 2019.
• 1. Rand MD
  2. Vorojeikina D
  3. Peppriell A
  4. Gunderson J
  5. Prince LM
  Drosophotoxicology: Elucidating Kinetic and Dynamic Pathways of Methylmercury Toxicity in a Drosophila Model.; Frontiers in genetics; Vol 10. 2019.
• 1. Klocke C
  2. Sherina V
  3. Graham UM
  4. Gunderson J
  5. Allen JL
  6. Sobolewski M
  7. Blum JL
  8. Zelikoff JT
  9. Cory-Slechta DA
  Enhanced cerebellar myelination with concomitant iron elevation and ultrastructural irregularities following prenatal exposure to ambient particulate matter in the mouse.; Inhalation toxicology. 2018 Dec 20.
• 1. Georas S
  2. Ransom N
  3. Hillman S
  4. Eliseeva S
  5. Veazey J
  6. Smyth T
  7. Le K
  8. Meddings J
  The leaky lung test: A pilot study using inhaled mannitol to measure airway barrier function in asthma.; The Journal of asthma : official journal of the Association for the Care of Asthma. 2018 Nov 16.
• 1. Spinelli P
  2. Latchney SE
  3. Reed JM
  4. Fields A
  5. Baier BS
  6. Lu X
  7. McCall MN
  8. Murphy SP
  9. Mak W
  10. Susiarjo M
  Identification of the novel Ido1 imprinted locus and its potential epigenetic role in pregnancy loss.; Human molecular genetics. 2018 Nov 07.
• 1. Beach TA
  2. Groves AM
  3. Williams JP
  4. Finkelstein JN
  Modeling radiation-induced lung injury: lessons learned from whole thorax irradiation.; International journal of radiation biology. 2018 Oct 25.
• 1. Morris-Schaffer K
  2. Sobolewski M
  3. Welle K
  4. Conrad K
  5. Yee M
  6. O'Reilly MA
  7. Cory-Slechta DA
  Cognitive flexibility deficits in male mice exposed to neonatal hyperoxia followed by concentrated ambient ultrafine particles.; Neurotoxicology and teratology. 2018 Oct 11.
• 1. Beach TA
  2. Groves AM
  3. Johnston CJ
  4. Williams JP
  5. Finkelstein JN
  Recurrent DNA damage is associated with persistent injury in progressive radiation-induced pulmonary fibrosis.; International journal of radiation biology. 2018 Sep 21.
• 1. Sobolewski M
  2. Anderson T
  3. Conrad K
  4. Marvin E
  5. Klocke C
  6. Morris-Schaffer K
  7. Allen JL
  8. Cory-Slechta DA
  Developmental Exposures to Ultrafine Particle Air Pollution Reduces Early Testosterone Levels and Adult Male Social Novelty Preference: Risk for Children's Sex-Biased Neurobehavioral Disorders.; Neurotoxicology. 2018 Aug 22.
• 1. Robert J
  2. McGuire CC
  3. Kim F
  4. Nagel SC
  5. Price SJ
  6. Lawrence BP
  7. De Jesús Andino F
  Water contaminants associated with unconventional oil and gas extraction cause immunotoxicity to amphibian tadpoles.; Toxicological sciences : an official journal of the Society of Toxicology. 2018 Jul 11.
• 1. Duffney PF
  2. Falsetta ML
  3. Rackow AR
  4. Thatcher TH
  5. Phipps RP
  6. Sime PJ
  Key roles for lipid mediators in the adaptive immune response.; The Journal of clinical investigation; Vol 128(7). 2018 Jul 02.
• 1. Morris-Schaffer K
  2. Sobolewski M
  3. Allen JL
  4. Marvin E
  5. Yee M
  6. Arora M
  7. O'Reilly MA
  8. Cory-Slechta DA
  Effect of neonatal hyperoxia followed by concentrated ambient ultrafine particle exposure on cumulative learning in C57Bl/6J mice.; Neurotoxicology. 2018 Jun 16.
• 1. Latchney SE
  2. Fields AM
  3. Susiarjo M
  Linking inter-individual variability to endocrine disruptors: insights for epigenetic inheritance.; Mammalian genome : official journal of the International Mammalian Genome Society; Vol 29(1-2). 2018 Feb.
• 1. Judge JL
  2. Nagel DJ
  3. Owens KM
  4. Rackow A
  5. Phipps RP
  6. Sime PJ
  7. Kottmann RM
  Prevention and treatment of bleomycin-induced pulmonary fibrosis with the lactate dehydrogenase inhibitor gossypol.; PloS one; Vol 13(5). 2018.
• 1. Stowell RD
  2. Wong EL
  3. Batchelor HN
  4. Mendes MS
  5. Lamantia CE
  6. Whitelaw BS
  7. Majewska AK
  Cerebellar microglia are dynamically unique and survey Purkinje neurons in vivo.; Developmental neurobiology. 2017 Dec 29.
• 1. Prince LM
  2. Rand MD
  Methylmercury exposure causes a persistent inhibition of myogenin expression and C2C12 myoblast differentiation.; Toxicology. 2017 Nov 02.
• 1. Wong EL
  2. Lutz NM
  3. Hogan VA
  4. Lamantia CE
  5. McMurray HR
  6. Myers JR
  7. Ashton JM
  8. Majewska AK
  Developmental alcohol exposure impairs synaptic plasticity without overtly altering microglial function in mouse visual cortex.; Brain, behavior, and immunity. 2017 Sep 13.
• 1. Resseguie EA
  2. Brookes PS
  3. O'Reilly MA
  SMG-1 kinase attenuates mitochondrial ROS production but not cell respiration deficits during hyperoxia.; Experimental lung research. 2017 Jul 27.
• 1. Jatana S
  2. Palmer BC
  3. Phelan SJ
  4. DeLouise LA
  Immunomodulatory Effects of Nanoparticles on Skin Allergy.; Scientific reports; Vol 7(1). 2017 Jun 21.
• 1. Beach TA
  2. Johnston CJ
  3. Groves AM
  4. Williams JP
  5. Finkelstein JN
  Radiation induced pulmonary fibrosis as a model of progressive fibrosis: Contributions of DNA damage, inflammatory response and cellular senescence genes.; Experimental lung research. 2017 May 23.
• 1. Judge JL
  2. Lacy SH
  3. Ku WY
  4. Owens KM
  5. Hernady E
  6. Thatcher TH
  7. Williams JP
  8. Phipps RP
  9. Sime PJ
  10. Kottmann RM
  The Lactate Dehydrogenase Inhibitor Gossypol Inhibits Radiation-Induced Pulmonary Fibrosis.; Radiation research. 2017 May 02.
• 1. Jatana S
  2. Palmer BC
  3. Phelan SJ
  4. Gelein R
  5. DeLouise LA
  In vivo quantification of quantum dot systemic transport in C57BL/6 hairless mice following skin application post-ultraviolet radiation.; Particle and fibre toxicology; Vol 14(1). 2017 Apr 14.
• 1. Prince LM
  2. Rand MD
  Notch Target Gene E(spl)mδ Is a Mediator of Methylmercury-Induced Myotoxicity in Drosophila.; Frontiers in genetics; Vol 8. 2017.
• 1. Beier EE
  2. Sheu TJ
  3. Resseguie EA
  4. Takahata M
  5. Awad HA
  6. Cory-Slechta DA
  7. Puzas JE
  Sclerostin activity plays a key role in the negative effect of glucocorticoid signaling on osteoblast function in mice.; Bone research; Vol 5. 2017.
• 1. Wong EL
  2. Stowell RD
  3. Majewska AK
  What the Spectrum of Microglial Functions Can Teach us About Fetal Alcohol Spectrum Disorder.; Frontiers in synaptic neuroscience; Vol 9. 2017.
• 1. Palmer BC
  2. DeLouise LA
  Nanoparticle-Enabled Transdermal Drug Delivery Systems for Enhanced Dose Control and Tissue Targeting.; Molecules (Basel, Switzerland); Vol 21(12). 2016 Dec 15.
• 1. Sobolewski M
  2. Allen JL
  3. Morris-Schaffer K
  4. Klocke C
  5. Conrad K
  6. Cory-Slechta DA
  A novel, ecologically relevant, highly preferred, and non-invasive means of oral substance administration for rodents.; Neurotoxicology and teratology. 2016 Apr 14.
• 1. Kottmann RM
  2. Trawick E
  3. Judge JL
  4. Wahl LA
  5. Epa AP
  6. Owens KM
  7. Thatcher TH
  8. Phipps RP
  9. Sime PJ
  Pharmacologic inhibition of lactate production prevents myofibroblast differentiation.; American journal of physiology. Lung cellular and molecular physiology; Vol 309(11). 2015 Dec 1.
• 1. Judge JL
  2. Owens KM
  3. Pollock SJ
  4. Woeller CF
  5. Thatcher TH
  6. Williams JP
  7. Phipps RP
  8. Sime PJ
  9. Kottmann RM
  Ionizing radiation induces myofibroblast differentiation via lactate dehydrogenase.; American journal of physiology. Lung cellular and molecular physiology; Vol 309(8). 2015 Oct 15.
• 1. Lantz CL
  2. Sipe GO
  3. Wong EL
  4. Majewska AK
  5. Medina AE
  Effects of Developmental Alcohol Exposure on Potentiation and Depression of Visual Cortex Responses.; Alcoholism, clinical and experimental research; Vol 39(8). 2015 Aug.
• 1. Resseguie EA
  2. Staversky RJ
  3. Brookes PS
  4. O'Reilly MA
  Hyperoxia activates ATM independent from mitochondrial ROS and dysfunction.; Redox biology; Vol 5. 2015 Aug.
• 1. Winans B
  2. Nagari A
  3. Chae M
  4. Post CM
  5. Ko CI
  6. Puga A
  7. Kraus WL
  8. Lawrence BP
  Linking the aryl hydrocarbon receptor with altered DNA methylation patterns and developmentally induced aberrant antiviral CD8+ T cell responses.; Journal of immunology (Baltimore, Md. : 1950); Vol 194(9). 2015 May 1.
• 1. Gerber SA
  2. Cummings RJ
  3. Judge JL
  4. Barlow ML
  5. Nanduri J
  6. Johnson DE
  7. Palis J
  8. Pentland AP
  9. Lord EM
  10. Ryan JL
  Interleukin-12 preserves the cutaneous physical and immunological barrier after radiation exposure.; Radiation research; Vol 183(1). 2015 Jan.
• 1. Prince L
  2. Korbas M
  3. Davidson P
  4. Broberg K
  5. Rand MD
  Target organ specific activity of drosophila MRP (ABCC1) moderates developmental toxicity of methylmercury.; Toxicological sciences : an official journal of the Society of Toxicology; Vol 140(2). 2014 Aug 1.
• 1. Allen JL
  2. Liu X
  3. Weston D
  4. Prince L
  5. Oberdörster G
  6. Finkelstein JN
  7. Johnston CJ
  8. Cory-Slechta DA
  Developmental exposure to concentrated ambient ultrafine particulate matter air pollution in mice results in persistent and sex-dependent behavioral neurotoxicity and glial activation.; Toxicological sciences : an official journal of the Society of Toxicology; Vol 140(1). 2014 Jul.
• 1. Rand MD
  2. Montgomery SL
  3. Prince L
  4. Vorojeikina D
  Developmental toxicity assays using the Drosophila model.; Current protocols in toxicology / editorial board, Mahin D. Maines (editor-in-chief) ... [et al.]; Vol 59. 2014.