Faculty Research Interests
Francis Gigliotti, M.D., Chief
- Pneumocystis carinii pneumonia
- Infections in the immunocompromised host
- Inflammatory lung injury
- Opportunistic infections
Samir Bhagwat, Ph.D.
- Monoclonal antibodies for the study of P. carinii
- Lung damage from P. carinii: pathogenesis and prevention
- Chemokine regulation of immune cell recruitment during Pneumocystis pneumonia
Mary T. Caserta, M.D.
- Viral respiratory infections in infants and children
- Effects of psychosocial factors on susceptibility to infectious diseases
- Epidemiology and clinical consequences of infection with human herpesvirus-6 and herpesvirus-7 in children with special emphasis on epidemiology and pathogenesis
- Member of the Collaborative Anti-viral Study Group (CASG) (See Current Studies.)
Cynthia Christy, M.D.
- Improving medical education especially relating to professionalism issues.
Jennifer Nayak, M.D.
- Understanding how a child's early exposure to influenza shapes immunity and poises the immune system to respond to subsequent influenza challenge
- Utilizing CD4 T cell-mediated immunity to improve vaccines directed against pandemic strains of influenza
- Understanding how pre-existing CD4 T cells directed against influenza influence the ability of B cells to respond to influenza vaccination
Brenda Tesini, M.D.
- Immune response to respiratory infections in both immunocompromised and immunocompetent hosts
Jing Wang, Ph.D.
- Macrophage mediated fungal clearance and lung injury during Pneumocystis pneumonia
- Mechanism of immune mediated lung injury during infectious diseases
- Seeking new strategies to treat inflammatory lung diseases
Geoffrey A. Weinberg, M.D.
- Integration of vaccine-preventable enteric and respiratory disease epidemiologic and laboratory surveillance with research on the improvement of vaccine delivery and efficacy (New Vaccine Surveillance Network, funded by CDC contract);
- Clinical trials of new pharmaceuticals, biologics, and vaccines in children and pregnant women infected with HIV (International Maternal, Pediatric, and Adolescent Clinical Trials Network, funded by NIH/NICHD contract).
Melanie Wellington, M.D., Ph.D.
- Host defense against infection with Candida
- Fungal pathogenesis
- Programmed cell death pathways in the immune response to fungi
Terry W. Wright, Ph.D.
- Role of alveolar epithelial cells in respiratory pathogen detection
- Modulation of T cell immune responses as adjunctive therapy for PcP
- Macrophage phenotype: modulation of inflammation and host defense