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Pediatrics / Palis Lab / Publications


  • Stolla MC, Kingsley PD, Grant R, Koniski A, Vit L, Catherman SC, Fegan KH, McGrath KE, Daley GQ, Palis J. "Lin28b regulates age-dependent differences in platelet function." Blood Advances. In press
  • McGrath KE, Catherman S, Palis J. "Delineating stages of erythropoiesis using imaging flow cytometry." Methods 112:68-74, 2017.
  • Frame JM, Fegan KH, Conway S, McGrath KE, Palis J. "Definitive hematopoiesis in the yolk sac emerges from Wnt-responsive hemogenic endothelium independently of circulation and arterial identity." Stem Cells 34:431-444, 2016.
  • Hyrien O, Peslak SA, Yanev NM, Palis J. "A stochastic model of stress erythropoiesis using a two-type age-dependent branching process with immigration." Journal of Mathematical Biology, 70:1485-1521, 2015.
  • McGrath KE, Frame JM, Fegan KM, Bowen JR, Conway SJ, Catherman SC, Kingsley PD, Koniski AD, Palis J. "Distinct sources of hematopoietic progenitors emerge before HSC and provide functional blood cells in the mammalian embryo." Cell Reports 11:1892-1904, 2015.
  • Kim AR, Olsen J, England SJ, Huang Y-S, Fegan KH, Delgadillo L, McGrath KE, Kingsley PD, Waugh R, Palis J. "Bmi-1 regulates extensive erythroid self-renewal." Stem Cell Reports 4:995-1003, 2015
  • Palis J. "Primitive and definitive erythropoiesis in mammals." Frontiers in Physiology 5:3, 2014.
  • Niswander LM, Kingsley PD, McGrath KE, Palis J. "SDF-1 dynamically regulates megakaryocyte niche occupancy and thrombopoiesis." Blood 124:277-286, 2014.
  • Niswander LM, McGrath KE, Kennedy JC, Palis J. "Improved quantitative analysis of primary bone marrow megakaryocytes utilizing imaging flow cytometry." Cytometry Part A 85:302-312, 2014.
  • Frame JM, McGrath KE, Palis J. "Erythro-myeloid progenitors: “definitive” hematopoiesis in the conceptus prior to the emergence of hematopoietic stem cells." Blood Cells, Molecules Diseases 51:220-225, 2013.
  • Malik J, Kim AR, Tyre KA, Cherukuri AR, Palis J. "Erythropoietin critically regulates murine and human primitive erythroblast survival and terminal maturation." Haematologica 98:1778-1787, 2013.
  • Kingsley PD, Greenfest-Allen E, Frame JM, Bushnell TP, Malik J, McGrath KE, Stoeckert CJ Jr, Palis J. "Ontogeny of erythroid gene expression." Blood 121:e5-e13, 2013.
  • Peslak SA, Wenger J, Bemis JC, Kingsley PD, Koniski AD, McGrath KE, Palis J. "EPO-mediated expansion of late-stage erythroid progenitors in the bone marrow initiates recovery from sublethal radiation stress." Blood 120:2501-2511, 2012
  • McGrath KE, Frame JM, Fromm GJ, Koniski AD, Kingsley PD, Little J, Bulger M, Palis J. "A transient definitive erythroid lineage with unique regulation of the beta-globin locus in the mammalian embryo." Blood 117:4600-4608, 2011.
  • Peslak SA, Wenger J, Bemis JC, Kingsley PD, Koniski AD, Chen Y, Williams JP, McGrath KE, Dertinger SD, Palis J. "Sublethal radiation injury uncovers a functional transition during erythroid maturation." Experimental Hematology 39:434-445, 2011.
  • England SJ, McGrath KE, Frame J, Palis J. "Immature erythroblasts with extensive ex vivo self-renewal capacity emerge from the early mammalian fetus." Blood, 117:2708-2717, 2011.
  • McGrath KE, Bushnell T, Palis J. "Multispectral imaging of hematopoietic cells: where flow meets morphology." Journal of Immunological Methods 336:91-97, 2008.
  • Palis J. "Ontogeny of erythropoiesis." Current Opinion in Hematology 15:155-161, 2008.
  • Tober J, McGrath KE, Palis J. "Primitive erythropoiesis and megakaryopoiesis in the yolk sac are independent of c-myb." Blood 111:2636-2639, 2008.
  • McGrath KE, Kingsley PD, Koniski AD, Porter RL, Bushnell TP, Palis J. "Enucleation of primitive erythroid cells generates a transient population of “pyrenocytes” in the mammalian fetus." Blood 111:2409-2417, 2008.
  • Dertinger S, Tsai Y, Nowak I, Hyrien O, Bemis J, Keng P, Palis J, Chen Y. "Reticulocyte and micronucleated reticulocyte responses to gamma irradiation: dose-response and time-course profiles measured by flow cytometry." Mutation Research 634:119-125, 2007.
  • Tober J, Koniski A, McGrath KE, Vemishetti R, Emerson R, de Mesy-Bentley KKL, Waugh R, Palis J. "The megakaryocyte lineage originates from hemangioblast precursors and is an integral component both of primitive and definitive hematopoiesis." Blood 109:1433-1441, 2007.
  • Kingsley PD, Malik J, Emerson RL, Bushnell TP, McGrath KE, Bloedorn LA, Bulger M, Palis J. “Maturational” globin switching in primary primitive erythroid cells." Blood 107:1667-1672, 2006.
  • McGrath KE, Palis J. "Yolk sac hematopoiesis: more than meets the eye." Experimental Hematology 33:1021-1028, 2005.
  • Huber TL, Kouskoff V,  Fehling HJ, Palis J*, Keller G*. "Haemangioblast commitment is initiated in the primitive streak of the mouse embryo." Nature 432:625-630, 2004. (*corresponding authors)
  • Kingsley PD, Malik J, Fantauzzo KA, Palis J. "Yolk sac-derived primitive erythroblasts enucleate during mammalian embryogenesis." Blood 104:19-25, 2004. (Plenary paper)
  • McGrath KE, Koniski AD, Malik J, Palis J. "Circulation is established in a step-wise pattern in the mammalian embryo." Blood 101:1669-1676, 2003. (Plenary paper)
  • Palis J, Yoder M. "Yolk sac hematopoiesis- the first blood cells of mouse and man." Experimental Hematology 29:927-936, 2001.
  • Palis J, Chan RJ, Koniski A, Patel R, Starr M, Yoder MC. "Spatial and temporal emergence of high proliferative potential hematopoietic precursors during murine embryogenesis." Proceedings National Academy of Science USA 98:4528-4533, 2001.
  • Palis J, Kennedy M, Robertson S, Wall C, Keller G. "Development of erythroid and myeloid progenitors in the yolk sac and embryo proper of the mouse embryo." Development 126:5073-5084, 1999.
  • McGrath KE, Koniski AD, Maltby KM, McGann JK, Palis J. "Embryonic expression and function of the chemokine SDF-1 and its receptor, CXCR4." Developmental Biology 213:442-456, 1999.
  • Palis J, Segel GB. "Developmental biology of erythropoiesis." Blood Reviews 12:106-114, 1998.
  • McGrath KE, Palis J. "Expression of homeobox genes, including an insulin promoting factor, in the murine yolk sac at the time of hematopoietic initiation." Molecular Reproduction and Development 48:145-153, 1997.
  • McGann JK, Silver L, Liesveld J, Palis J. "Erythropoietin-receptor expression and function during the initiation of murine yolk sac erythropoiesis." Experimental Hematology 25:1149-1157, 1997.
  • Silver L, Palis J. "Initiation of murine yolk sac hematopoiesis: a spatial analysis." Blood 89:1154-1164, 1997.
  • Palis J, Kingsley PD, McGrath KE. "Initiation of hematopoiesis and vasculogenesis in murine yolk sac explants." Blood  86:156-163, 1995.