
Welcome to the Steiner Laboratory

The Steiner Lab investigates the molecular and genetic mechanisms that regulate red blood cell development. Anemia, or low red blood cell count, is the most common hematologic disorder in both children and adults. Our research integrates genomic, molecular, and cellular approaches to uncover the fundamental processes that sustain healthy blood formation and whose disruption contributes to hematologic disease.
We also collaborate on clinical and translational studies that explore the genetic and molecular basis of human developmental and blood disorders. Our work has contributed to identifying and characterizing pathogenic gene variants in rare congenital syndromes and has revealed signaling and epigenetic pathways that may serve as therapeutic targets for anemia.
The Steiner Lab fosters a collaborative and supportive environment that values curiosity, rigor, and teamwork. We are deeply committed to training the next generation of scientists, providing mentorship and opportunities for students and postdoctoral fellows to grow as independent and creative researchers.

Laurie A. Steiner, M.D.
Principal Investigator
- BMI1 regulates human erythroid self-renewal through both gene repression and gene activation.; Nature communications; Vol 16(1), pp. 7619. 2025 Aug 15.
- Histone H4 lysine 20 methylation marks genes dynamically regulated during erythroid maturation.; Epigenetics & chromatin; Vol 18(1), pp. 48. 2025 Jul 26.
- The Condensin II complex regulates essential gene expression programs during erythropoiesis.; Development (Cambridge, England); Vol 152(10). 2025 May 19.
- Differences in outcomes associated with ABO blood groups in recipients of IVIG.; Blood vessels, thrombosis & hemostasis; Vol 2(3), pp. 100075. 2025 May 09.
Contact Us
Steiner Lab
University of Rochester Medical Center
Center for Children's Health Research
601 Elmwood Ave.
Box 651
Rochester, NY 14642