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Linda Marie Callahan, Ph.D.

Linda Marie Callahan, Ph.D.



About Me

Faculty Appointments

Assistant Professor (Service) - Department of Neuroscience (SMD)

Assistant Professor (Service) - Department of Pathology and Laboratory Medicine (SMD) - Joint


Post-doctoral Training & Residency

University of Rochester Medical Center, Department of Neurobiology and Anatomy, Neurodegeneration 1991 - 1995


Postdoctoral Fellow, Alzheimer's Disease Center | University of Rochester Medical Center. 1995

PhD | Albany Medical College. Neurobiology. 1991

MS | University of Vermont. Pathology. 1984

BS | St Lawrence University. Biology. 1980


NEGEA Ambassador. 2023

Special Commendation: Excellence in First Year Teaching. 2022

Dean's Teaching Fellowship. 2017 - 2019

URSMD Strong Star Award. 2014

Invitation to Editorial Board, Journal of Neuropathology and Experimental Neurology. 2004 - 2004

Nominee, Student Employee Supervisor of the Year Award. 1998

NIH First Award (R29). 1997

Mary Notter Award for Excellence in Research. 1994

Albany Medical College Alumni Association Award. 1991

Who's Who Among Students in American Universities and Colleges. 1990

"Dean's Certificate and Prize for Excellence in Teaching", Albany Medical College Courses taught: Histology, Gross Anatomy. 1989


Journal Articles

Tissue-Like 3D Standard and Protocols for Microscope Quality Management.

Abrams B, Pengo T, Wee TL, Deagle RC, Vuillemin N, Callahan LM, Smith MA, Kubow KE, Girard AM, Rappoport JZ, Bayles CJ, Cameron LA, Cole R, Brown CM

Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada.. 2023 April 529 (2):616-634. Epub 1900 01 01.

Tissue-Like 3D Standard and Protocols for Microscope Quality Management.

Abrams B; Pengo T; Wee T-L; Deagle RC; Vuillemin N; Callahan LM; Smith MA; Kubow K; Girard A-M; Rappoport JZ; Bayles CJ; Cameron LA; Cole R; Brown CM.

Microscopy and Microanalysis. 2023; 29(2): 616-634.

Impact of Cosmetic Lotions on Nanoparticle Penetration through C57BL/6 Hairless Mouse and Human Skin: A Comparison Study.

Jatana S, Callahan LM, Pentland AP, DeLouise LA

Cosmetics.. 2016 March 3 (1)Epub 02/19/2016.

Development and characterization of antibody reagents for detecting nanoparticles.

Ravichandran S, Sullivan MA, Callahan LM, Bentley KL, DeLouise LA

Nanoscale.. 2015 December 217 (47):20042-54. Epub 11/16/2015.

Differences in amygdala cell proliferation between adolescent and young adult rats.

Saul ML, Helmreich DL, Callahan LM, Fudge JL

Developmental psychobiology.. 2014 April 56 (3):517-28. Epub 06/15/2013.

The ligand-mediated nuclear mobility and interaction with estrogen-responsive elements of estrogen receptors are subtype specific.

Muyan M, Callahan LM, Huang Y, Lee AJ

Journal of molecular endocrinology.. 2012 December 49 (3):249-66. Epub 10/30/2012.

Epithelial ablation of Bcl-XL increases sensitivity to oxygen without disrupting lung development.

Staversky RJ, Vitiello PF, Yee M, Callahan LM, Dean DA, O'Reilly MA

American journal of respiratory cell and molecular biology.. 2010 September 43 (3):376-85. Epub 10/30/2009.

A neurotoxic phosphoform of Elk-1 associates with inclusions from multiple neurodegenerative diseases.

Sharma A, Callahan LM, Sul JY, Kim TK, Barrett L, Kim M, Powers JM, Federoff H, Eberwine J

PloS one.. 2010 February 25 (2):e9002. Epub 02/02/2010.

Chronic neuron-specific tumor necrosis factor-alpha expression enhances the local inflammatory environment ultimately leading to neuronal death in 3xTg-AD mice.

Janelsins MC, Mastrangelo MA, Park KM, Sudol KL, Narrow WC, Oddo S, LaFerla FM, Callahan LM, Federoff HJ, Bowers WJ

The American journal of pathology.. 2008 December 173 (6):1768-82. Epub 10/30/2008.

VIP is a transcriptional target of Nurr1 in dopaminergic cells.

Luo Y, Henricksen LA, Giuliano RE, Prifti L, Callahan LM, Federoff HJ

Experimental neurology.. 2007 January 203 (1):221-32. Epub 09/26/2006.

Dysregulation of gene expression in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse substantia nigra.

Miller RM, Callahan LM, Casaceli C, Chen L, Kiser GL, Chui B, Kaysser-Kranich TM, Sendera TJ, Palaniappan C, Federoff HJ

The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2004 August 2524 (34):7445-54. Epub 1900 01 01.

Progressive reduction of synaptophysin message in single neurons in Alzheimer disease.

Callahan LM, Vaules WA, Coleman PD

Journal of neuropathology and experimental neurology.. 2002 May 61 (5):384-95. Epub 1900 01 01.

Myotonic dystrophy in transgenic mice expressing an expanded CUG repeat.

Mankodi, A. Logician, E., Callahan L.M., McClain C.W., Henderson, D., Krym, M., Thornton, CA.

Science. 2000; 289: 1769-1772.

Cyclooxygenase-1 in human Alzheimer and control brain: quantitative analysis of expression by microglia and CA3 hippocampal neurons.

Yermakova AV, Rollins J, Callahan LM, Rogers J, O'Banion MK

Journal of neuropathology and experimental neurology.. 1999 November 58 (11):1135-46. Epub 1900 01 01.

Quantitative decrease in synaptophysin message expression and increase in cathepsin D message expression in Alzheimer disease neurons containing neurofibrillary tangles.

Callahan LM, Vaules WA, Coleman PD

Journal of neuropathology and experimental neurology.. 1999 March 58 (3):275-87. Epub 1900 01 01.

Changes in synaptic expression of clathrin assembly protein AP180 in Alzheimer's disease analysed by immunohistochemistry.

Yao PJ, Morsch R, Callahan LM, Coleman PD

Neuroscience.. 1999 94 (2):389-94. Epub 1900 01 01.

Expression profiles of multiple genes in single neurons of Alzheimer's disease.

Chow N, Cox C, Callahan LM, Weimer JM, Guo L, Coleman PD

Proceedings of the National Academy of Sciences of the United States of America.. 1998 August 495 (16):9620-5. Epub 1900 01 01.

Analysis of message expression in single neurons of Alzheimer's disease brain.

Callahan LM, Chow N, Cheetham JE, Cox C, Coleman PD

Neurobiology of aging.. 1998 19 (1 Suppl):S99-105. Epub 1900 01 01.

Neurons bearing neurofibrillary tangles are responsible for selected synaptic deficits in Alzheimer's disease.

Callahan LM, Coleman PD

Neurobiology of aging.. 1995 16 (3):311-4. Epub 1900 01 01.

Preliminary evidence: decreased GAP-43 message in tangle-bearing neurons relative to adjacent tangle-free neurons in Alzheimer's disease parahippocampal gyrus.

Callahan LM, Selski DJ, Martzen MR, Cheetham JE, Coleman PD

Neurobiology of aging.. 1994 15 (3):381-6. Epub 1900 01 01.

Cytoplasmic inclusions in spinal neurons of the motor neuron degeneration (Mnd) mouse. I. Light microscopic analysis.

Mazurkiewicz JE, Callahan LM, Swash M, Martin JE, Messer A

Journal of the neurological sciences.. 1993 May 116 (1):59-66. Epub 1900 01 01.

Neurofilament distribution is altered in the Mnd (motor neuron degeneration) mouse.

Callahan LM, Wylen EL, Messer A, Mazurkiewicz JE

Journal of neuropathology and experimental neurology.. 1991 July 50 (4):491-504. Epub 1900 01 01.

Cellular alterations in the alveolar wall in bleomycin-induced pulmonary fibrosis in rats. An ultrastructural morphometric study.

Adler KB, Callahan LM, Evans JN

The American review of respiratory disease.. 1986 June 133 (6):1043-8. Epub 1900 01 01.

Alterations in the cellular population of the alveolar wall in an animal model of fibrosis. A morphometric study.

Callahan LM, Evans JN, Adler KB

Chest.. 1986 March 89 (3 Suppl):188S-189S. Epub 1900 01 01.


Connections, Cognition and Alzheimer's Disease (1997)

Chapter: Neurofibrillary tangles are associated with the differential loss of message expression for synaptic proteins in Alzheimer's Disease.

Authors: Callahan LM and Coleman PD

Publisher: Springer, New York City 1997