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Xi Wang, B.Med.

Xi Wang, B.Med.

UR Medicine Labs

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About Me

Dr. Wang is a surgical pathologist with a subspecialty interest in breast pathology.

Certified Specialties

Pathology, Anatomic Pathology & Clinical Pathology - American Board of Pathology

Faculty Appointments

Professor (Part-Time) - Department of Pathology and Laboratory Medicine (SMD)

Credentials

Residency & Fellowship

Fellowship, Pathology, Memorial Sloan-Kettering Cancer Center. 2001 - 2002

Residency, Pathology, Anatomic Pathology & Clinical Pathology, West Virginia University Hospitals. 1997 - 2001

Fellowship, Harvard School of Public Health. 1991 - 1997

Education

MB | Sun Yat-Sen University of Medical Sciences (China). 1989

MB | Sun Yat-Sen University of Medical Sciences (China). 1982

Research

Dr. Wang's current research interest is the use of immunohistochemical staining and molecular methods to identify tumor cell origin and differentiation.

Publications

Journal Articles

Performance of HER2 DAKO HercepTest and Ventana 4B5 Immunohistochemical Assays on Detecting HER2 Gene-Amplification in Uterine Serous Carcinomas.

Navarro Sanchez JM, Finkelman BS, Tyburski H, Turner BM, Moisini I, Katerji H, Varghese S, Wang X, Schiffhauer LM, Chen JJ, Hicks DG, Zhang H

Human pathology.. 2024 May 11 Epub 05/11/2024.

HER2 in uterine serous carcinoma: Current state and clinical perspectives.

Navarro Sanchez JM, Finkelman BS, Turner BM, Katerji H, Wang X, Varghese S, Wang T, Peng Y, Hicks DG, Zhang H

American journal of clinical pathology.. 2023 June 2 Epub 06/02/2023.

Interobserver and Interantibody Reproducibility of HER2 Immunohistochemical Scoring in an Enriched HER2-Low-Expressing Breast Cancer Cohort.

Karakas C, Tyburski H, Turner BM, Wang X, Schiffhauer LM, Katerji H, Hicks DG, Zhang H

American journal of clinical pathology.. 2023 February 28 Epub 02/28/2023.

The Rochester Modified Magee Algorithm (RoMMa): An Outcomes Based Strategy for Clinical Risk-Assessment and Risk-Stratification in ER Positive, HER2 Negative Breast Cancer Patients Being Considered for Oncotype DX Testing.

Turner BM, Finkelman BS, Hicks DG, Numbereye N, Moisini I, Dhakal A, Skinner K, Sanders MAG, Wang X, Shayne M, Schiffhauer L, Katerji H, Zhang H

Cancers.. 2023 January 3115 (3)Epub 01/31/2023.

HER2-low breast cancers: Current insights and future directions.

Zhang H, Karakas C, Tyburski H, Turner BM, Peng Y, Wang X, Katerji H, Schiffhauer L, Hicks DG

Seminars in diagnostic pathology.. 2022 July 9 Epub 07/09/2022.

Inflammatory breast cancer with excellent response to pembrolizumab-chemotherapy combination: A case report.

Kharel Z, Nemer OP, Xi W, Upadhayaya B, Falkson CI, O'Regan RM, Dhakal A

Breast disease.. 2022 41 (1):255-260. Epub 1900 01 01.

Erratum to: Inflammatory breast cancer with excellent response to pembrolizumab-chemotherapy combination: A case report.

Kharel Z, Nemer OP, Xi W, Upadhayaya B, Falkson CI, O'Regan RM, Dhakal A

Breast disease.. 2022 41 (1):363. Epub 1900 01 01.

Interobserver Agreement in the Diagnosis of Anal Dysplasia: Comparison Between Gastrointestinal and Gynaecologic Pathologists and Utility of Consensus Conferences.

Abu-Farsakh S, Drage MG, Huber AR, Turner BM, Varghese S, Wang X, Whitney-Miller CL, Gonzalez RS

Histopathology.. 2021 October 3 Epub 10/03/2021.

Histiocytic Sarcoma Arising From a Long Bone: Report of Two Cases.

Ajabnoor R, Bell PD, Schiffman S, Carmody E, Monu J, Wang X

International journal of surgical pathology.. 2021 March 22 :1066896921996464. Epub 03/22/2021.

Significance of HER2 in Microinvasive Breast Carcinoma.

Zhang H, Moisini I, Turner BM, Wang X, Dhakal A, Yang Q, Kovar S, Schiffhauer LM, Hicks DG

American journal of clinical pathology.. 2021 January 25 Epub 01/25/2021.

Frequency, Clinicopathologic Characteristics, and Follow-up of HER2-Positive Nonpleomorphic Invasive Lobular Carcinoma of the Breast.

Zhang H, Moisini I, Ajabnoor RM, Turner BM, D'aguiar M, Cai X, Gao S, Yang Q, Wang X, Schiffhauer L, Hicks DG

American journal of clinical pathology.. 2019 November 30 Epub 11/30/2019.

Focal Anomalous Expression of Cytokeratin and p63 in Malignant Phyllodes Tumor: A Comparison With Spindle Cell Metaplastic Carcinoma.

Bansal M, Chen J, Wang X

Applied immunohistochemistry & molecular morphology : AIMM. 2018 March 26 (3):198-201. Epub 1900 01 01.

p53 alteration in morphologically normal/benign breast luminal cells in BRCA carriers with or without history of breast cancer.

Wang X, El-Halaby AA, Zhang H, Yang Q, Laughlin TS, Rothberg PG, Skinner K, Hicks DG

Human pathology.. 2017 October 68 :22-25. Epub 04/21/2017.

p53 alteration in morphologically normal/benign breast tissue in patients with triple-negative high-grade breast carcinomas: breast p53 signature?

Wang X, Stolla M, Ring BZ, Yang Q, Laughlin TS, Rothberg PG, Skinner K, G Hicks D

Human pathology.. 2016 September 55 :196-201. Epub 05/28/2016.

Interaction between Oc-1 and Lmx1a promotes ventral midbrain dopamine neural stem cells differentiation into dopamine neurons.

Yuan J, Lei ZN, Wang X, Deng YJ, Chen DB

Brain research.. 2015 May 221608 :40-50. Epub 03/05/2015.

Expression of a-Tocopherol-Associated protein (TAP) is associated with clinical outcome in breast cancer patients.

Wang X, Ring BZ, Seitz RS, Ross DT, Woolf K, Beck RA, Hicks DG, Yeh S

BMC clinical pathology. 2015 15 :21. Epub 12/09/2015.

Expression of androgen receptor and its association with estrogen receptor and androgen receptor downstream proteins in normal/benign breast luminal epithelium.

Wang X, Yarid N, McMahon L, Yang Q, Hicks DG

Applied immunohistochemistry & molecular morphology : AIMM. 2014 August 22 (7):498-504. Epub 1900 01 01.

A lower Allred score for progesterone receptor is strongly associated with a higher recurrence score of 21-gene assay in breast cancer.

Tang P, Wang J, Hicks DG, Wang X, Schiffhauer L, McMahon L, Yang Q, Shayne M, Huston A, Skinner KA, Griggs J, Lyman G

Cancer investigation.. 2010 November 28 (9):978-82. Epub 1900 01 01.

Small neuroendocrine lesions in intrathoracic lymph nodes of patients with primary lung adenocarcinoma: real metastasis?

Li F, Wang X, Xu H, Roggli VL

The American journal of surgical pathology.. 2010 November 34 (11):1701-7. Epub 1900 01 01.

Reduced expression of tocopherol-associated protein (TAP/Sec14L2) in human breast cancer.

Wang X, Ni J, Hsu CL, Johnykutty S, Tang P, Ho YS, Lee CH, Yeh S

Cancer investigation.. 2009 December 27 (10):971-7. Epub 1900 01 01.

Reduced Expression of Tocopherol-Associated Protein (TAP/Sec14L2) in Human Breast Cancer.

Wang X, Ni J, Hsu CL, Johnykutty S, Tang P, Ho YS, Lee CH, Yeh S

Cancer investigation.. 2009 June 22 :1. Epub 6/22/2009.

Dual expression of alpha-tocopherol-associated protein and estrogen receptor in normal/benign human breast luminal cells and the downregulation of alpha-tocopherol-associated protein in estrogen-receptor-positive breast carcinomas.

Johnykutty S, Tang P, Zhao H, Hicks DG, Yeh S, Wang X

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.. 2009 June 22 (6):770-5. Epub 03/20/2009.

Generation and characterization of a complete null estrogen receptor alpha mouse using Cre/LoxP technology.

Chen M, Wolfe A, Wang X, Chang C, Yeh S, Radovick S

Molecular and cellular biochemistry.. 2009 January 321 (1-2):145-53. Epub 10/25/2008.

A 46 XY phenotypic female adolescent with bilateral gonadal tumors consisting of five different components.

Simon RA, Laughlin TS, Nuccie B, Wang N, Rothberg PG, Wang X

International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists.. 2008 July 27 (3):407-11. Epub 1900 01 01.

Relationship between nuclear grade of ductal carcinoma in situ and cell origin markers.

Tang P, Wang X, Schiffhauer L, Wang J, Bourne P, Yang Q, Quinn A, Hajdu SI

Annals of clinical and laboratory science.. 2006 36 (1):16-22. Epub 1900 01 01.

Expression patterns of ER-alpha, PR, HER-2/neu, and EGFR in different cell origin subtypes of high grade and non-high grade ductal carcinoma in situ.

Tang P, Wang X, Schiffhauer L, Wang J, Bourne P, Yang Q, Quinn A, Hajdu S

Annals of clinical and laboratory science.. 2006 36 (2):137-43. Epub 1900 01 01.

Wilms Tumor Gene (WT1) and p53 expression in endometrial carcinomas: a study of 130 cases using a tissue microarray.

Dupont J, Wang X, Marshall DS, Leitao M, Hedvat CV, Hummer A, Thaler H, O'Reilly RJ, Soslow RA

Gynecologic oncology.. 2004 August 94 (2):449-55. Epub 1900 01 01.

Multiple chromosome abnormalities following bone marrow transplant for chronic myelogenous leukemia

Wang X; Ahmed I; Ericson S; Wenger S.

The Journal of the Association of Genetic Technologists. 2004; 30: 7-9.

Carcinogen exposure, p53 alteration, and K-ras mutation in synchronous multiple primary lung carcinoma.

Wang X, Christiani DC, Mark EJ, Nelson H, Wiencke JK, Gunn L, Wain JC, Kelsey KT

Cancer.. 1999 April 1585 (8):1734-9. Epub 1900 01 01.

Constitutional alterations in p16 in patients with uveal melanoma.

Wang X, Egan KM, Gragoudas ES, Kelsey KT

Melanoma research.. 1996 December 6 (6):405-10. Epub 1900 01 01.

A polymorphism in the delta-aminolevulinic acid dehydratase gene may modify the pharmacokinetics and toxicity of lead.

Smith CM, Wang X, Hu H, Kelsey KT

Environmental health perspectives.. 1995 March 103 (3):248-53. Epub 1900 01 01.

Altered p53 status correlates with differences in sensitivity to radiation-induced mutation and apoptosis in two closely related human lymphoblast lines.

Xia F, Wang X, Wang YH, Tsang NM, Yandell DW, Kelsey KT, Liber HL

Cancer research.. 1995 January 155 (1):12-5. Epub 1900 01 01.

Mutations in the p53 gene in lung cancer are associated with cigarette smoking and asbestos exposure

Wang X; Christiani DC; Mark EJ; Kelsey KT.

Cancer Epidemiology, Biomarkers & Prevention. 1995; 4: 543-548.

Books

Occupational Lung Disease (1997)

Chapter: Lung carcinogenesis: molecular and cellular mechanisms

Authors: Kelsey KT; Nelson H; Wang X

Publisher: Thomas Science & Professional 1997