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Robert H. Notter, M.D., Ph.D.

Publications

Showing all 158 journal articles & 29 books available

Journal Articles

2011
Willson, D; Egan, EA; Notter, RH. "Exogenous surfactant in the pediatric patient." Pediatric and Neonatal Mechanical Ventilation, Rimensberger PC (Ed.): Springer-Verlag. 2011; .

2011
Raghavendran, KR; Willson, D; Notter, RH. "Surfactant therapy of ALI/ARDS." Crit Care Clin. 2011; .

2011
Willson,D; Notter, RH. "New Horizons. The future of exogenous surfactant therapy." J Respir Care. 2011; .

1/13/2010
Walther FJ, Waring AJ, Hernandez-Juviel JM, Gordon LM, Wang Z, Jung CL, Ruchala P, Clark AP, Smith WM, Sharma S, Notter RH. "Critical structural and functional roles for the N-terminal insertion sequence in surfactant protein B analogs." PloS one. 2010 Jan 13; 5(1):e8672. Epub 2010 Jan 13.

10/2009
Yee M, Chess PR, McGrath-Morrow SA, Wang Z, Gelein R, Zhou R, Dean DA, Notter RH, O'Reilly MA. "Neonatal oxygen adversely affects lung function in adult mice without altering surfactant composition or activity." American journal of physiology. Lung cellular and molecular physiology.. 2009 Oct 0; 297(4):L641-9. Epub 2009 Jul 17.

8/2009
Raghavendran K, Notter RH, Davidson BA, Helinski JD, Kunkel SL, Knight PR. "Lung contusion: inflammatory mechanisms and interaction with other injuries." Shock.. 2009 Aug 0; 32(2):122-30.

8/2009
Raghavendran K, Davidson BA, Huebschmann JC, Helinski JD, Hutson AD, Dayton MT, Notter RH, Knight PR. "Superimposed gastric aspiration increases the severity of inflammation and permeability injury in a rat model of lung contusion." The Journal of surgical research.. 2009 Aug 0; 155(2):273-82. Epub 2008 Sep 16.

4/2009
Schwab U, Rohde KH, Wang Z, Chess PR, Notter RH, Russell DG. "Transcriptional responses of Mycobacterium tuberculosis to lung surfactant." Microbial pathogenesis.. 2009 Apr 0; 46(4):185-93. Epub 2009 Jan 14.

2009
Raghavendran K; Davidson BA, Hutson AD; Helinski JD; Nodzo SR; Notter RH; Knight PR. "Predictive modeling and inflammatory biomarkers in rats with lung contusion and gastric aspiration." J Trauma.2009; Dec;67(6):1182-90. 2009; .

11/2008
Raghavendran K, Davidson BA, Knight PR, Wang Z, Helinski J, Chess PR, Notter RH. "Surfactant dysfunction in lung contusion with and without superimposed gastric aspiration in a rat model." Shock.. 2008 Nov 0; 30(5):508-17.

5/2008
Wang Z, Schwab U, Rhoades E, Chess PR, Russell DG, Notter RH. "Peripheral cell wall lipids of Mycobacterium tuberculosis are inhibitory to surfactant function." Tuberculosis.. 2008 May 0; 88(3):178-86. Epub 2007 Dec 21.

2008
Willson, DF.; Chess, PR,; Notter, RH. "Surfactant for pediatric acute lung injury." Pediatr Clin N Am. 2008; : Jun;55:545-575.

2008
Raghavendran K, Pryhuber GS, Chess PR, Davidson BA, Knight PR, Notter RH. "Pharmacotherapy of acute lung injury and acute respiratory distress syndrome." Current medicinal chemistry. 2008 15(19):1911-24.

10/2007
Wang Z, Chang Y, Schwan AL, Notter RH. "Activity and inhibition resistance of a phospholipase-resistant synthetic surfactant in rat lungs." American journal of respiratory cell and molecular biology.. 2007 Oct 0; 37(4):387-94. Epub 2007 Jun 07.

9/2007
Russo TA, Davidson BA, Beanan JM, Olson R, Holm BA, Notter RH, Knight PR. "Capsule and O-antigen from an extraintestinal isolate of Escherichia coli modulate cytokine levels in rat macrophages in vitro and in a rat model of pneumonia." Experimental lung research.. 2007 Sep 0; 33(7):337-56.

9/2007
Notter RH, Schwan AL, Wang Z, Waring AJ. "Novel phospholipase-resistant lipid/peptide synthetic lung surfactants." Mini reviews in medicinal chemistry.. 2007 Sep 0; 7(9):932-44.

3/2007
Russo TA, Wang Z, Davidson BA, Genagon SA, Beanan JM, Olson R, Holm BA, Knight PR, Chess PR, Notter RH. "Surfactant dysfunction and lung injury due to the E. coli virulence factor hemolysin in a rat pneumonia model." American journal of physiology. Lung cellular and molecular physiology.. 2007 Mar 0; 292(3):L632-43.

1/1/2007
Notter RH, Wang Z, Wang Z, Davy JA, Schwan AL. "Synthesis and surface activity of diether-linked phosphoglycerols: potential applications for exogenous lung surfactants." Bioorganic & medicinal chemistry letters.. 2007 Jan 1; 17(1):113-7. Epub 2006 Sep 30.

1/2007
Hickman-Davis JM, Wang Z, Fierro-Perez GA, Chess PR, Page GP, Matalon S, Notter RH. "Surfactant dysfunction in SP-A-/- and iNOS-/- mice with mycoplasma infection." American journal of respiratory cell and molecular biology.. 2007 Jan 0; 36(1):103-13. Epub 2006 Aug 17.

2007
Russo, T.; Wang, Z.; Davidson, B.; Genagon, S.; Beanan, J.; Olsen, R.; Holm, B.; Knight, P.; Chess, P.; Notter, R. "Surfactant dysfunction and lung injury due to the E. colil virulence factor hemolysin in a rat pneumonia model." Am J Physiol. 2007; 292: L632-L643.

2007
Davy, J.; Wang, Z.; Notter, RH.; Schwan, AL. "Synthesis of sulfur-containing glycerophospholipids." J Sulfur Chem. 2007; 28: 45-72.

2007
Walther, F.; Waring, A.; Hernandez-Juviel, J.; Gordon, L.; Schwan, A.; Chang, Y.; Wang, Z.; Notter, R. "Dynamic surface activity of a fully-synthetic phospholipase-resistant lipid/peptide lung surfactant." Dynamic surface activity of a fully-synthetic phospholipase-resistant lipid/peptide lung surfactant. 2007; 2(10): 1-10: e1039. doi:10.1371.

6/2006
Bruckner L, Gigliotti F, Wright T, Harmsen A, Notter RH, Chess P, Wang Z, Finkelstein J. "Pneumocystis carinii infection sensitizes lung to radiation-induced injury after syngeneic marrow transplantation: role of CD4+ T cells." American journal of physiology. Lung cellular and molecular physiology.. 2006 Jun 0; 290(6):L1087-96. Epub 2006 Jan 06.

1/2006
Hutson AD, Davidson BA, Raghavendran K, Chess PR, Tait AR, Holm BA, Notter RH, Knight PR. "Statistical prediction of the type of gastric aspiration lung injury based on early cytokine/chemokine profiles." Anesthesiology.. 2006 Jan 0; 104(1):73-9.

11/2005
Raghavendran K, Davidson BA, Helinski JD, Marschke CJ, Manderscheid P, Woytash JA, Notter RH, Knight PR. "A rat model for isolated bilateral lung contusion from blunt chest trauma." Anesthesia and analgesia.. 2005 Nov 0; 101(5):1482-9.

10/2005
Chang Y, Wang Z, Schwan AL, Wang Z, Holm BA, Baatz JE, Notter RH. "Surface properties of sulfur- and ether-linked phosphonolipids with and without purified hydrophobic lung surfactant proteins." Chemistry and physics of lipids.. 2005 Oct 0; 137(1-2):77-93.

8/2005
Raghavendran K, Davidson BA, Woytash JA, Helinski JD, Marschke CJ, Manderscheid PA, Notter RH, Knight PR. "The evolution of isolated bilateral lung contusion from blunt chest trauma in rats: cellular and cytokine responses." Shock.. 2005 Aug 0; 24(2):132-8.

7/2005
Raghavendran K, Davidson BA, Mullan BA, Hutson AD, Russo TA, Manderscheid PA, Woytash JA, Holm BA, Notter RH, Knight PR. "Acid and particulate-induced aspiration lung injury in mice: importance of MCP-1." American journal of physiology. Lung cellular and molecular physiology.. 2005 Jul 0; 289(1):L134-43. Epub 2005 Mar 18.

6/2005
Wang Z, Foye A, Chang Y, Chess PR, Wright TW, Bhagwat S, Gigliotti F, Notter RH. "Inhibition of surfactant activity by Pneumocystis carinii organisms and components in vitro." American journal of physiology. Lung cellular and molecular physiology.. 2005 Jun 0; 288(6):L1124-31.

4/2005
Davidson BA, Knight PR, Wang Z, Chess PR, Holm BA, Russo TA, Hutson A, Notter RH. "Surfactant alterations in acute inflammatory lung injury from aspiration of acid and gastric particulates." American journal of physiology. Lung cellular and molecular physiology.. 2005 Apr 0; 288(4):L699-708.

4/2005
Davidson BA, Stewart CC, Russo TA, Chess PR, Knight PR. "Discrimination of resident and infiltrated alveolar macrophages by flow cytometry in influenza A virus-infected mice." Experimental lung research.. 2005 Apr 0; 31(3):323-39.

3/1/2005
Biswas N, Shanmukh S, Waring AJ, Walther F, Wang Z, Chang Y, Notter RH, Dluhy RA. "Structure and properties of phospholipid-peptide monolayers containing monomeric SP-B(1-25) I. Phases and morphology by epifluorescence microscopy." Biophysical chemistry. 2005 Mar 1; 113(3):223-32.

3/1/2005
Shanmukh S, Biswas N, Waring AJ, Walther FJ, Wang Z, Chang Y, Notter RH, Dluhy RA. "Structure and properties of phospholipid-peptide monolayers containing monomeric SP-B(1-25) II. Peptide conformation by infrared spectroscopy." Biophysical chemistry. 2005 Mar 1; 113(3):233-44.

2005
Raghavendran K, Manderscheid PA, Notter RH, Knight PR. "Host-bacterial interactions in the lungs in the perioperative period". Res Signpost: Recent Res Develop Microbiol. 2005; 9: 159-181.

2005
Raghavendran K, Davidson BA, Chess PR, Nader N, Notter RH, Knight PR. "Acute inflammatory gastric aspiration-related lung injury". Current Respir Med Rev. 2005; 1: 279-290.

2005
Elder A, Johnston C, Gelein R, Finkelstein J, Wang Z, Notter R, Oberdörster G. "Lung inflammation induced by endotoxin is enhanced in rats depleted of alveolar macrophages with aerosolized clodronate." Experimental lung research.. 2005 31(6):527-46.

12/20/2004
Chang Y, Wang Z, Notter RH, Wang Z, Qu L, Schwan AL. "Synthesis and interfacial behavior of sulfur-containing analogs of lung surfactant dipalmitoyl phosphatidylcholine." Bioorganic & medicinal chemistry letters.. 2004 Dec 20; 14(24):5983-6.

3/2004
Elder ACP, Gelein R, Finkelstein J, Wang Z, Notter RH, Oberdoerster G. "Efficient depletion of alveolar macrophages using intratracheally-inhaled aerosols of liposome-encapsulated clodronate". Experimental Lung Res. 2004; 30((2)): 105-120.

2/15/2004
Wright TW, Pryhuber GS, Chess PR, Wang Z, Notter RH, Gigliotti F. "TNF receptor signaling contributes to chemokine secretion, inflammation, and respiratory deficits during Pneumocystis pneumonia." The Journal of immunology : official journal of the American Association of Immunologists.. 2004 Feb 15; 172(4):2511-21.

2004
Notter RH, Holm BA. "Basic science research on clinical exogenous surfactants: composition, activity, viscosity, and utility in lung injury". Neonatal Intensive Care. 2004; 17((Suppl)): S3-S7.

2004
Stevens TP, Sinkin RA, Notter RH, Wang Z, Consenstein L, Maniscalco WM. "Alternative Strategies for Dispensing Exogenous Surfactant: Drug Cost Implications and In Vitro Feasibility Studies". Hospital Pharmacy. 2004; 39: 338-345.

2004
Knight PR, Davidson BA, Nader ND, Helinski JD, Marschke CJ, Russo TA, Hutson AD, Notter RH, Holm BA. "Progressive, severe lung injury secondary to the interaction of insults in gastric aspiration." Experimental lung research.. 2004 30(7):535-57.

9/2003
Wang Z, Schwan AL, Lairson LL, O'Donnell JS, Byrne GF, Foye A, Holm BA, Notter RH. "Surface activity of a synthetic lung surfactant containing a phospholipase-resistant phosphonolipid analog of dipalmitoyl phosphatidylcholine." American journal of physiology. Lung cellular and molecular physiology.. 2003 Sep 0; 285(3):L550-9.

1/2003
Brockman JM, Wang Z, Notter RH, Dluhy RA. "Effect of hydrophobic surfactant proteins SP-B and SP-C on binary phospholipid monolayers: II. Infrared external reflectance-absorption spectroscopy." Biophysical journal.. 2003 Jan 0; 84(1):326-40.

11/2002
Wang Z, Baatz JE, Holm BA, Notter RH. "Content-dependent activity of lung surfactant protein B in mixtures with lipids." American journal of physiology. Lung cellular and molecular physiology.. 2002 Nov 0; 283(5):L897-906.

9/2002
Russo TA, Bartholomew LA, Davidson BA, Helinski JD, Carlino UB, Knight PR, Beers MF, Atochina EN, Notter RH, Holm BA. "Total extracellular surfactant is increased but abnormal in a rat model of gram-negative bacterial pneumonia." American journal of physiology. Lung cellular and molecular physiology.. 2002 Sep 0; 283(3):L655-63.

2/2002
King DM, Wang Z, Palmer HJ, Holm BA, Notter RH. "Bulk shear viscosities of endogenous and exogenous lung surfactants." American journal of physiology. Lung cellular and molecular physiology.. 2002 Feb 0; 282(2):L277-84.

1/2002
Notter RH, Wang Z, Egan EA, Holm BA. "Component-specific surface and physiological activity in bovine-derived lung surfactants." Chemistry and physics of lipids.. 2002 Jan 0; 114(1):21-34.

10/2001
Baatz JE, Zou Y, Cox JT, Wang Z, Notter RH. "High-yield purification of lung surfactant proteins sp-b and sp-c and the effects on surface activity." Protein expression and purification.. 2001 Oct 0; 23(1):180-90.

7/2001
King DM, Wang Z, Kendig JW, Palmer HJ, Holm BA, Notter RH. "Concentration-dependent, temperature-dependent non-Newtonian viscosity of lung surfactant dispersions." Chemistry and physics of lipids.. 2001 Jul 0; 112(1):11-9.

2/2001
Wright TW, Notter RH, Wang Z, Harmsen AG, Gigliotti F. "Pulmonary inflammation disrupts surfactant function during Pneumocystis carinii pneumonia." Infection and immunity.. 2001 Feb 0; 69(2):758-64.

10/2000
Uy IP, Pryhuber GS, Chess PR, Notter RH. "Combined-modality therapy with inhaled nitric oxide and exogenous surfactant in term infants with acute respiratory failure." Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.. 2000 Oct 0; 1(2):107-10.

6/2000
Knight PR, Kurek C, Davidson BA, Nader ND, Patel A, Sokolowski J, Notter RH, Holm BA. "Acid aspiration increases sensitivity to increased ambient oxygen concentrations." American journal of physiology. Lung cellular and molecular physiology.. 2000 Jun 0; 278(6):L1240-7.

2000
Notter RH, Apostolakos M, Holm BA, Willson D, Wang Z, Finkelstein JN, Hyde RW. "Surfactant therapy and its potential use with other agents in term neonates, children, and adults with acute lung injury". Perspectives Neonatol. 2000; 1((4)): 4-20.

2000
Notter RH, Wang Z, Holm BA. "Function and dysfunction of endogenous and exogenous lung surfactants". Res Advances Lipids. 2000; 1: 73-105.

9/1999
Gernon MD, Turcotte JG, Notter RH, Mu M, Lear Y, Snelgrove JL, Schwan AL. "The reaction of thiolates with 2,3-dibromo-1-propanol revisited: application to the synthesis of bis(fattyalkylthio)propanols." Chemistry and physics of lipids.. 1999 Sep 0; 101(2):215-22.

8/1999
Krüger P, Schalke M, Wang Z, Notter RH, Dluhy RA, Lösche M. "Effect of hydrophobic surfactant peptides SP-B and SP-C on binary phospholipid monolayers. I. Fluorescence and dark-field microscopy." Biophysical journal.. 1999 Aug 0; 77(2):903-14.

7/1999
Holm BA, Wang Z, Notter RH. "Multiple mechanisms of lung surfactant inhibition." Pediatric research.. 1999 Jul 0; 46(1):85-93.

7/1998
Wang Z, Notter RH. "Additivity of protein and nonprotein inhibitors of lung surfactant activity." American journal of respiratory and critical care medicine.. 1998 Jul 0; 158(1):28-35.

6/1998
Kendig JW, Ryan RM, Sinkin RA, Maniscalco WM, Notter RH, Guillet R, Cox C, Dweck HS, Horgan MJ, Reubens LJ, Risemberg H, Phelps DL. "Comparison of two strategies for surfactant prophylaxis in very premature infants: a multicenter randomized trial." Pediatrics.. 1998 Jun 0; 101(6):1006-12.

10/1997
Wang Z, Gurel O, Weinbach S, Notter RH. "Primary importance of zwitterionic over anionic phospholipids in the surface-active function of calf lung surfactant extract." American journal of respiratory and critical care medicine.. 1997 Oct 0; 156(4 Pt 1):1049-57.

4/1997
D'Angio CT, Finkelstein JN, Lomonaco MB, Paxhia A, Wright SA, Baggs RB, Notter RH, Ryan RM. "Changes in surfactant protein gene expression in a neonatal rabbit model of hyperoxia-induced fibrosis." The American journal of physiology.. 1997 Apr 0; 272(4 Pt 1):L720-30.

1997
Notter RH, Wang Z. "Pulmonary surfactant: Physical chemistry, physiology, and replacement". Rev Chem Engin. 1997; 13: 1-118.

8/9/1996
Wang Z, Gurel O, Baatz JE, Notter RH. "Acylation of pulmonary surfactant protein-C is required for its optimal surface active interactions with phospholipids." The Journal of biological chemistry.. 1996 Aug 9; 271(32):19104-9.

8/1996
Wang Z, Gurel O, Baatz JE, Notter RH. "Differential activity and lack of synergy of lung surfactant proteins SP-B and SP-C in interactions with phospholipids." Journal of lipid research.. 1996 Aug 0; 37(8):1749-60.

5/1996
Holm BA, Wang Z, Egan EA, Notter RH. "Content of dipalmitoyl phosphatidylcholine in lung surfactant: ramifications for surface activity." Pediatric research.. 1996 May 0; 39(5):805-11.

4/1996
Wang Z, Hall SB, Notter RH. "Roles of different hydrophobic constituents in the adsorption of pulmonary surfactant." Journal of lipid research.. 1996 Apr 0; 37(4):790-8.

6/1995
Wang Z, Hall SB, Notter RH. "Dynamic surface activity of films of lung surfactant phospholipids, hydrophobic proteins, and neutral lipids." Journal of lipid research.. 1995 Jun 0; 36(6):1283-93.

5/1995
Skita V, Chester DW, Oliver CJ, Turcotte JG, Notter RH. "Bilayer characteristics of a diether phosphonolipid analog of the major lung surfactant glycerophospholipid dipalmitoyl phosphatidylcholine." Journal of lipid research.. 1995 May 0; 36(5):1116-27.

1995
Liu H, Turcotte JG, Notter RH. "Thermotropic behavior of structurally-related phospholipids and phosphonolipid analogs of lung surfactant glycerophospholipids". Langmuir. 1995; 11: 101-107.

1995
Ge Z, Brown CW, Turcotte JG, Wang Z, Notter RH. "FTIR studies of calcium-dependent molecular order in lung surfactant and surfactant extract dispersions". J Colloid Interface Sci. 1995; 173: 471-477.

10/1994
Dizon-Co L, Ikegami M, Ueda T, Jobe AH, Lin WH, Turcotte JG, Notter RH, Rider ED. "In vivo function of surfactants containing phosphatidylcholine analogs." American journal of respiratory and critical care medicine.. 1994 Oct 0; 150(4):918-23.

8/1994
Hall SB, Wang Z, Notter RH. "Separation of subfractions of the hydrophobic components of calf lung surfactant." Journal of lipid research.. 1994 Aug 0; 35(8):1386-94.

5/1994
Hall SB, Hyde RW, Notter RH. "Changes in subphase aggregates in rabbits injured by free fatty acid." American journal of respiratory and critical care medicine.. 1994 May 0; 149(5):1099-106.

1994
Liu H, Lu Z, Turcotte JG, Notter RH. "Dynamic interfacial properties of surface-excess films of phospholipid and phosphonolipid analogs: I. Effects of pH". J Colloid Interface Sci. 1994; 167: 378-390.

1994
Liu H, Turcotte JG, Notter RH. "Dynamic interfacial properties of surface-excess films of phospholipid and phosphonolipid analogs: II. Effects of chain linkage and headgroup structure". J Colloid Interface Sci. 1994; 167: 391-400.

7/1993
Hall SB, Bermel MS, Ko YT, Palmer HJ, Enhorning G, Notter RH. "Approximations in the measurement of surface tension on the oscillating bubble surfactometer." Journal of applied physiology.. 1993 Jul 0; 75(1):468-77.

6/1992
Davis JM, Richter SE, Kendig JW, Notter RH. "High-frequency jet ventilation and surfactant treatment of newborns with severe respiratory failure." Pediatric pulmonology.. 1992 Jun 0; 13(2):108-12.

5/1992
Hall SB, Lu RZ, Venkitaraman AR, Hyde RW, Notter RH. "Inhibition of pulmonary surfactant by oleic acid: mechanisms and characteristics." Journal of applied physiology.. 1992 May 0; 72(5):1708-16.

1/1992
Hall SB, Venkitaraman AR, Whitsett JA, Holm BA, Notter RH. "Importance of hydrophobic apoproteins as constituents of clinical exogenous surfactants." The American review of respiratory disease.. 1992 Jan 0; 145(1):24-30.

1992
Lu RZ, Turcotte JG, Lin WH, Steim JM, Notter RH. "Differential scanning calorimetry studies of phosphonolipid analogs of lung surfactant phospholipids". J Colloid Interface Sci. 1992; : 24-34.

6/19/1991
Turcotte JG, Lin WH, Pivarnik PE, Sacco AM, Shirali SS, Bermel MM, Lu Z, Notter RH. "Chemical synthesis and surface activity of lung surfactant phospholipid analogs. II. Racemic N-substituted diether phosphonolipids." Biochimica et biophysica acta.. 1991 Jun 19; 1084(1):1-12.

3/28/1991
Kendig JW, Notter RH, Cox C, Reubens LJ, Davis JM, Maniscalco WM, Sinkin RA, Bartoletti A, Dweck HS, Horgan MJ. "A comparison of surfactant as immediate prophylaxis and as rescue therapy in newborns of less than 30 weeks' gestation." The New England journal of medicine.. 1991 Mar 28; 324(13):865-71.

1/1991
Auten RL, Notter RH, Kendig JW, Davis JM, Shapiro DL. "Surfactant treatment of full-term newborns with respiratory failure." Pediatrics.. 1991 Jan 0; 87(1):101-7.

1991
Turcotte JG, Lin WH, Motola NC, Pivarnik PE, Bhongle NN, Heyman HR, Shirali SS, Lu Z, Notter RH. "Chemical synthesis and surface activity of lung surfactant phospholipid analogs. III. Chiral N-substituted ether-amide phosphonolipids." Chemistry and physics of lipids.. 1991 58(1-2):81-95.

1991
Venkitaraman AR, Baatz JE, Whitsett JA, Hall SB, Notter RH. "Biophysical inhibition of synthetic phospholipid-lung surfactant apoprotein admixtures by plasma proteins." Chemistry and physics of lipids.. 1991 57(1):49-57.

12/1990
Venkitaraman AR, Hall SB, Whitsett JA, Notter RH. "Enhancement of biophysical activity of lung surfactant extracts and phospholipid-apoprotein mixtures by surfactant protein A." Chemistry and physics of lipids.. 1990 Dec 0; 56(2-3):185-94.

9/1990
Hall SB, Notter RH, Smith RJ, Hyde RW. "Altered function of pulmonary surfactant in fatty acid lung injury." Journal of applied physiology.. 1990 Sep 0; 69(3):1143-9.

5/1/1990
Farrell PM, Bourbon JR, Notter RH, Marin L, Nogee LM, Whitsett JA. "Relationships among surfactant fraction lipids, proteins and biophysical properties in the developing rat lung." Biochimica et biophysica acta.. 1990 May 1; 1044(1):84-90.

5/1990
Davis JM, Metlay LA, Dickerson B, Penney DP, Notter RH. "Early pulmonary changes associated with high-frequency jet ventilation in newborn piglets." Pediatric research.. 1990 May 0; 27(5):460-5.

3/1990
Venkitaraman AR, Hall SB, Notter RH. "Hydrophobic homopolymeric peptides enhance the biophysical activity of synthetic lung phospholipids." Chemistry and physics of lipids.. 1990 Mar 0; 53(2-3):157-64.

2/1990
Horowitz S, Shapiro DL, Finkelstein JN, Notter RH, Johnston CJ, Quible DJ. "Changes in gene expression in hyperoxia-induced neonatal lung injury." The American journal of physiology.. 1990 Feb 0; 258(2 Pt 1):L107-11.

2/1990
Holm BA, Venkitaraman AR, Enhorning G, Notter RH. "Biophysical inhibition of synthetic lung surfactants." Chemistry and physics of lipids.. 1990 Feb 0; 52(3-4):243-50.

9/1989
Davis JM, Penney DP, Notter RH, Metlay L, Dickerson B, Shapiro DL. "Lung injury in the neonatal piglet caused by hyperoxia and mechanical ventilation." Journal of applied physiology.. 1989 Sep 0; 67(3):1007-12.

5/5/1989
Horowitz S, Dafni N, Shapiro DL, Holm BA, Notter RH, Quible DJ. "Hyperoxic exposure alters gene expression in the lung. Induction of the tissue inhibitor of metalloproteinases mRNA and other mRNAs." The Journal of biological chemistry.. 1989 May 5; 264(13):7092-5.

3/1989
Loewen GM, Holm BA, Milanowski L, Wild LM, Notter RH, Matalon S. "Alveolar hyperoxic injury in rabbits receiving exogenous surfactant." Journal of applied physiology.. 1989 Mar 0; 66(3):1087-92.

12/1988
Shapiro DL, Notter RH. "Controversies regarding surfactant replacement therapy." Clinics in perinatology.. 1988 Dec 0; 15(4):891-902.

12/1988
Gleason CA, Jones MD, Traystman RJ, Notter RH. "Fetal cerebral responses to ventilation and oxygenation in utero." The American journal of physiology.. 1988 Dec 0; 255(6 Pt 2):R1049-54.

12/1988
Holm BA, Matalon S, Finkelstein JN, Notter RH. "Type II pneumocyte changes during hyperoxic lung injury and recovery." Journal of applied physiology.. 1988 Dec 0; 65(6):2672-8.

11/1988
Kendig JW, Notter RH, Cox C, Aschner JL, Benn S, Bernstein RM, Hendricks-Munoz K, Maniscalco WM, Metlay LA, Phelps DL. "Surfactant replacement therapy at birth: final analysis of a clinical trial and comparisons with similar trials." Pediatrics.. 1988 Nov 0; 82(5):756-62.

11/1988
Holm BA, Enhorning G, Notter RH. "A biophysical mechanism by which plasma proteins inhibit lung surfactant activity." Chemistry and physics of lipids.. 1988 Nov 0; 49(1-2):49-55.

8/25/1988
Davis JM, Veness-Meehan K, Notter RH, Bhutani VK, Kendig JW, Shapiro DL. "Changes in pulmonary mechanics after the administration of surfactant to infants with respiratory distress syndrome." The New England journal of medicine.. 1988 Aug 25; 319(8):476-9.

7/1988
Notter RH. "Biophysical behavior of lung surfactant: implications for respiratory physiology and pathophysiology." Seminars in perinatology.. 1988 Jul 0; 12(3):180-212.

1988
Matalon S, Holm BA, Loewen GM, Baker RR, Notter RH. "Sublethal hyperoxic injury to the alveolar epithelium and the pulmonary surfactant system." Experimental lung research.. 1988 14 Suppl:1021-33.

10/1987
Wood BP, Sinkin RA, Kendig JW, Notter RH, Shapiro DL. "Exogenous lung surfactant: effect on radiographic appearance in premature infants." Radiology.. 1987 Oct 0; 165(1):11-3.

10/1987
Holm BA, Notter RH. "Effects of hemoglobin and cell membrane lipids on pulmonary surfactant activity." Journal of applied physiology.. 1987 Oct 0; 63(4):1434-42.

9/1987
Notter RH, Shapiro DL. "Lung surfactants for replacement therapy: biochemical, biophysical, and clinical aspects." Clinics in perinatology.. 1987 Sep 0; 14(3):433-79.

6/1987
Notter RH, Shapiro DL, Ohning B, Whitsett JA. "Biophysical activity of synthetic phospholipids combined with purified lung surfactant 6000 dalton apoprotein." Chemistry and physics of lipids.. 1987 Jun 0; 44(1):1-17.

6/1987
Holm BA, Notter RH, Leary JF, Matalon S. "Alveolar epithelial changes in rabbits after a 21-day exposure to 60% O2." Journal of applied physiology.. 1987 Jun 0; 62(6):2230-6.

2/1987
Matalon S, Holm BA, Notter RH. "Mitigation of pulmonary hyperoxic injury by administration of exogenous surfactant." Journal of applied physiology.. 1987 Feb 0; 62(2):756-61.

1987
Bermel MS, Turcotte JG, Steim J, Notter RH. "Interfacial properties of arabinofuranosylcytosine diphosphate diacylglycerol, a synthetic liponucleotide". J Colloid Interface Sci. 1987; 115: 167-175.

1987
Bhongle NN, Notter RH, Turcotte JG. "Expedient and high-yield synthesis of alkylphosphonyl dichlorides under mild, neutral conditions: reaction of bis (trimethylsilyl) alkyl phosphonates with oxalyl chloride/dimethylformamide". Synthetic Comm. 1987; 17: 1071-1076.

1987
Deluga KD, Cokelet GR, Notter RH, Shapiro DL. "The effect of lipid emulsions on neonatal and adult blood viscosity". J Clin Hemorheol. 1987; 7: 793-802.

10/25/1986
Ross GF, Notter RH, Meuth J, Whitsett JA. "Phospholipid binding and biophysical activity of pulmonary surfactant-associated protein (SAP)-35 and its non-collagenous COOH-terminal domains." The Journal of biological chemistry.. 1986 Oct 25; 261(30):14283-91.

9/1986
Leary JF, Finkelstein JN, Notter RH, Shapiro DL. "A quantitative study of the development of type II pneumocytes in fetal lung." Cytometry.. 1986 Sep 0; 7(5):431-8.

5/1986
Whitsett JA, Ohning BL, Ross G, Meuth J, Weaver T, Holm BA, Shapiro DL, Notter RH. "Hydrophobic surfactant-associated protein in whole lung surfactant and its importance for biophysical activity in lung surfactant extracts used for replacement therapy." Pediatric research.. 1986 May 0; 20(5):460-7.

1/1986
Notter RH, Penney DP, Finkelstein JN, Shapiro DL. "Adsorption of natural lung surfactant and phospholipid extracts related to tubular myelin formation." Pediatric research.. 1986 Jan 0; 20(1):97-101.

11/1985
Holm BA, Notter RH, Siegle J, Matalon S. "Pulmonary physiological and surfactant changes during injury and recovery from hyperoxia." Journal of applied physiology.. 1985 Nov 0; 59(5):1402-9.

10/1985
Kwong MS, Egan EA, Notter RH, Shapiro DL. "Double-blind clinical trial of calf lung surfactant extract for the prevention of hyaline membrane disease in extremely premature infants." Pediatrics.. 1985 Oct 0; 76(4):585-92.

10/1985
Shapiro DL, Notter RH, Morin FC, Deluga KS, Golub LM, Sinkin RA, Weiss KI, Cox C. "Double-blind, randomized trial of a calf lung surfactant extract administered at birth to very premature infants for prevention of respiratory distress syndrome." Pediatrics.. 1985 Oct 0; 76(4):593-9.

9/1985
Holm BA, Notter RH, Finkelstein JN. "Surface property changes from interactions of albumin with natural lung surfactant and extracted lung lipids." Chemistry and physics of lipids.. 1985 Sep 0; 38(3):287-98.

6/1985
Notter RH, Egan EA, Kwong MS, Holm BA, Shapiro DL. "Lung surfactant replacement in premature lambs with extracted lipids from bovine lung lavage: effects of dose, dispersion technique, and gestational age." Pediatric research.. 1985 Jun 0; 19(6):569-77.

1985
Wojciak JF, Oberdoerster G, Notter RH. "Size stability of phosphatidylcholine-phosphatidylglycerol aerosols and a dynamic film compression state from their interfacial impaction". J Colloid Interface Sci. 1985; 106: 547-557.

12/1984
Notter RH, Finkelstein JN. "Pulmonary surfactant: an interdisciplinary approach." Journal of applied physiology: respiratory, environmental and exercise physiology.. 1984 Dec 0; 57(6):1613-24.

12/1984
Gallo RL, Wersto RP, Notter RH, Finkelstein JN. "Lysophosphatidylcholine cell depolarization: increased membrane permeability for use in the determination of cell membrane potentials." Archives of biochemistry and biophysics.. 1984 Dec 0; 235(2):544-54.

4/11/1984
Gallo RL, Finkelstein JN, Notter RH. "Characterization of the plasma and mitochondrial membrane potentials of alveolar type II cells by the use of ionic probes." Biochimica et biophysica acta.. 1984 Apr 11; 771(2):217-27.

1984
Bermel MS, McBride JT, Notter RH. "Lavaged excised rat lungs as a model of surfactant deficiency." Lung.. 1984 162(2):99-113.

9/1983
Egan EA, Notter RH, Kwong MS, Shapiro DL. "Natural and artificial lung surfactant replacement therapy in premature lambs." Journal of applied physiology: respiratory, environmental and exercise physiology.. 1983 Sep 0; 55(3):875-83.

9/1983
Marks LB, Notter RH, Oberdorster G, McBride JT. "Ultrasonic and jet aerosolization of phospholipids and the effects on surface activity." Pediatric research.. 1983 Sep 0; 17(9):742-7.

7/1983
Notter RH, Finkelstein JN, Taubold RD. "Comparative adsorption of natural lung surfactant, extracted phospholipids, and artificial phospholipid mixtures to the air-water interface." Chemistry and physics of lipids.. 1983 Jul 0; 33(1):67-80.

1983
Marks LB, Oberdoerster G, Notter RH. "Generation and characterization of aerosols of dispersed surface-active phospholipids by ultrasonic and jet nebulization". J Aerosol Sci. 1983; 14: 783-794.

7/1982
Notter RH, Smith S, Taubold RD, Finkelstein JN. "Path dependence of adsorption behavior of mixtures containing dipalmitoyl phosphatidylcholine." Pediatric research.. 1982 Jul 0; 16(7):515-9.

5/1982
Notter RH, Taubold R, Mavis RD. "Hysteresis in saturated phospholipid films and its potential relevance for lung surfactant function in vivo." Experimental lung research.. 1982 May 0; 3(2):109-27.

3/1982
Leary JF, Finkelstein JN, Notter RH, Shapiro DL. "Isolation of type II pneumocytes by laser flow cytometry." The American review of respiratory disease.. 1982 Mar 0; 125(3):326-30.

2/1982
Notter RH, Shapiro DL, Taubold R, Chen J. "Bilirubin interactions with phospholipid components of lung surfactant." Pediatric research.. 1982 Feb 0; 16(2):130-6.

12/1981
Notter RH, Shapiro DL. "Lung surfactant in an era of replacement therapy." Pediatrics.. 1981 Dec 0; 68(6):781-9.

1/1980
Notter RH, Tabak SA, Mavis RD. "Surface properties of binary mixtures of some pulmonary surfactant components." Journal of lipid research.. 1980 Jan 0; 21(1):10-22.

1980
Notter RH, Tabak SA, Holcomb S, Mavis R. "Post-collapse dynamic surface pressure relaxation in binary surface films containing dipalmitoyl phosphatidylcholine". J Colloid Interface Sci. 1980; 74: 370-377.

1980
Notter RH, Holcomb S, Mavis RD. "Dynamic surface properties of phosphatidylglycerol-dipalmitoyl phosphatidylcholine mixed films". Chem Phys Lipids. 1980; 27: 305-319.

9/13/1979
Notter RH. "Surfactant composition in hyaline-membrane disease." The New England journal of medicine.. 1979 Sep 13; 301(11):612-3.

1979
Notter RH, Tam YM, Min S. "Steady non-ionic countergradient transport through membranes by coupled diffusion". A.I.Ch.E. Journal. 1979; 25: 469-478.

8/24/1977
Turcotte JG, Sacco AM, Steim JM, Tabak SA, Notter RH. "Chemical synthesis and surface properties of an analog of the pulmonary surfactant dipalmitoyl phosphatidylcholine." Biochimica et biophysica acta.. 1977 Aug 24; 488(2):235-48.

1977
Tabak SA, Notter RH. "Effect of plasma proteins on the dynamic pi-A characteristics of saturated phospholipid films". J Colloid Interface Sci. 1977; : 293-300.

1977
Tabak SA, Notter RH, Ultman JS, Dinh S. "Relaxation effects in the surface pressure behavior of dipalmitoyl lecithin". J Colloid Interface Sci. 1977; 60: 117-125.

1977
Tabak SA, Notter RH. "A modified technique for dynamic surface pressure and relaxation measurements at the air-water interface". Rev Sci Instruments. 1977; 48: 1196-1201.

1976
Min S, Duda JL, Notter RH, Vrentas JS. "An interferometric technique for the study of steady-state membrane transport". AIChE Journal. 1976; : 175-182.

6/1975
Notter RH, Morrow PE. "Pulmonary surfactant: a surface chemistry viewpoint." Annals of biomedical engineering.. 1975 Jun 0; 3(2):119-59.

1975
Notter RH, Sleicher CA. "Diffusivity ratios in fully developed turbulent flow". AIChE Journal. 1975; 21: 169-170.

1975
Duda JL, Malone M, Notter RH, Vrentas JS. "Analysis of two-dimensional diffusion controlled moving boundary problems". 1975; 18: 901-910.

1973
Sleicher CA, Awad AS, Notter RH. "Temperature and eddy diffusivity profiles in NaK". Int J Heat Mass Trans. 1973; 16: 1565-1575.

1973
Notter RH, Berg JC. "Transport resistance of dipalmitoyl and rat lung lecithin films". J Colloid Interface Sci. 1973; : 421-424.

1972
Notter RH, Sleicher CA. "A solution to the turbulent Graetz problem by matched asymptotic expansions - III. Fully developed and entry region heat transfer rates". Chem Engr Sci. 1972; 27: 2073-2093.

1971
Notter RH, Sleicher CA. "The eddy diffusivity in the turbulent boundary layer near a wall". Chem Engr Sci. 1971; 26: 161-171.

1971
Notter RH, Sleicher CA. "A solution to the turbulent Graetz problem by matched asymptotic expansions - II. The case of uniform wall heat flux". Chem Engr Sci. 1971; 26: 559-565.

1971
Notter RH, Sather NF. "Normal momentum transfer on ideal crystalline surfaces". AIAA Journal. 1971; 9: 965-966.

1970
Sleicher, C.A.; Notter, R.H.; Crippen, M. "A solution to the turbulent Graetz problem by matched asymptotic expansions - I. The case of uniform wall temperature." Chem Engr Sci. 1970; 25:: 845-857.

1970
Notter RH, Kaku YJ, Sather NF. "A molecular model for tangential momentum accommodation". AIAA Journal. 1970; 8: 2064-2066.

1969
Notter, R.H.; Sleicher, C.A. "The limiting form of the eddy diffusivity close to a wall." AIChE Journal. 1969; : 936-939.

Books & Chapters

2008
Chapter Title: Informa Healthcare, pp. 1683-1694
Book Title: Encyclopedia of Biomaterials and Biomedical Engineering, Vol. 3, 2nd Edition
Author List: Notter RH, Wang Z
Published By: Wnek GE, Bowlin GL (Eds)2008

2007
Chapter Title: Pulmonary surfactant: Biology and therapy
Book Title: Pediatric Critical Care Medicine: Basic Science and Clinical Evidence
Author List: Willson DF, Chess PR, Wang Z, Notter RH
Edited By: Wheeler DA, Wong HR, Shanley TA
Published By: Springer-Verlag2007 in London, England

2006
Chapter Title: Lung surfactant: An overview
Book Title: Encyclopedia of Respiratory Medicine
Author List: Notter RH, Wang Z, Chess PR
Edited By: Laurent GJ, Shapiro SD
Published By: Elsevier Publishers2006 in Oxford, England

2005
Chapter Title: Surfactant activity and dysfunction in lung injury
Book Title: Lung Injury: Mechanisms, Pathophysiology, and Therapy
Author List: Wang Z, Holm BA, Matalon S, Notter RH
Edited By: Notter RH, Finkelstein JN, Holm BA
Published By: Taylor & Francis Group2005 in Boca Raton, FL

2005
Chapter Title: Cell and animal models of lung injury
Book Title: Lung Injury: Mechanisms, Pathophysiology, and Therapy
Author List: Finkelstein JN, O'Reilly M, Holm BA, Chess PR, Notter RH
Edited By: Notter RH, Finkelstein JN, Holm BA
Published By: Taylor & Francis Group2005 in Boca Raton, FL

2005
Chapter Title: Surfactant replacement therapy in lung injury
Book Title: Lung Injury: Mechanisms, Pathophysiology, and Therapy
Author List: Chess PR, Finkelstein JN, Holm BA, Notter RH
Edited By: Notter RH, Finkelstein JN, Holm BA
Published By: Taylor & Francis Group2005 in Boca Raton, FL

2005
Chapter Title: Combined-modality therapies for lung injury
Book Title: Lung Injury: Mechanisms, Pathophysiology, and Therapy
Author List: Pryhuber GS, D'Angio CT, Finkelstein JN, Notter RH
Edited By: Notter RH, Finkelstein JN, Holm BA
Published By: Taylor & Francis Group2005 in Boca Raton, FL

2005
Book Title: Lung Injury: Mechanisms, Pathophysiology, and Therapy
Author List: Notter RH, Finkelstein JN, Holm BA (editors)
Edited By: Notter RH, Finkelstein JN, Holm BA
Published By: Taylor & Francis Group2005 in Boca Raton, FL

2004
Chapter Title: Lung surfactants
Book Title: Encyclopedia of Biomaterials and Biomedical Engineering
Author List: Notter RH, Wang Z
Edited By: Wnek GE, Bowlin GL
Published By: Marcel Dekker, Inc.2004 in New York, NY

2002
Chapter Title: Current Issues in Surfactant Replacement Therapy
Book Title: Enhorning Roundtable in Lung Research:
Author List: Notter RH, Holm BA (editors)
Edited By: Notter RH, Holm BA
Published By: Dannemiller Memorial Educational Foundation and MedPro Communications2002

2002
Chapter Title: Inhibition of lung surfactants and the importance of SP-B in inhibition resistance
Book Title: Enhorning Roundtable in Lung Research: Current Issues in Surfactant Replacement
Author List: Holm BA, Wang Z, Notter RH
Edited By: Holm BA, Notter RH
Published By: Dannemiller Memorial Educational Foundation and MedPro Communications2002

2000
Book Title: Lung surfactants: Basic science and clinical applications
Author List: Notter RH
Published By: Marcel Dekker2000 in New York, NY

2000
Book Title: Lung surfactants: Basic science and clinical applications
Author List: Notter RH
Published By: Marcel Dekker2000 in New York, NY

1994
Chapter Title: Lung surfactant replacement for neonatal pathology other than primary respiratory distress syndrome
Book Title: New therapies for neonatal respiratory failure: A physiologic approach
Author List: Davis JM, Notter RH
Edited By: Boynton B, Carlo W, Jobe A
Published By: Cambridge University Press1994 in New York, NY

1989
Chapter Title: The inhibition of surfactant function by plasma-derived protein
Book Title: Surfactant and the respiratory tract
Author List: Holm BA, Enhorning G, Notter RH
Edited By: Ekelund L, Jonson B, Malm L
Published By: Elsevier1989 in The Netherlands

1989
Chapter Title: The physical chemistry and physiological activity of pulmonary surfactants
Book Title: Surfactant replacement therapy
Author List: Notter RH
Edited By: Shapiro DL, Notter RH
Published By: AR Liss, Inc.1989 in New York, NY

1989
Chapter Title: Clinical experience with calf lung surfactant extract
Book Title: Surfactant replacement therapy
Author List: Kendig JW, Notter RH, Maniscalco WM, Davis JM, Shapiro DL
Edited By: Shapiro DL, Notter RH
Published By: AR Liss, Inc.1989 in New York, NY

1989
Chapter Title: Surfactant therapy in ARDS and lung injury
Book Title: Surfactant replacement therapy
Author List: Holm BA, Notter RH
Edited By: Shapiro DL, Notter RH
Published By: AR Liss, Inc.1989 in New York, NY

1989
Book Title: Surfactant replacement therapy
Author List: Shapiro DL, Notter RH (editors)
Edited By: Shapiro DL, Notter RH
Published By: AR Liss, Inc.1989 in New York, NY

1988
Chapter Title: Animal models for testing surfactants
Book Title: Surfactant treatment of lung diseases
Author List: Holm BA, Notter RH
Edited By: Jobe A, Taeusch HW
Published By: Ross Laboratories Press1988 in Columbus, OH

1988
Chapter Title: Pulmonary surfactant effects and replacement in oxygen toxicity and other ARDS-type lung injuries
Book Title: Surfactant replacement therapy in neonatal and adult respiratory distress syndro
Author List: Holm BA, Notter RH
Edited By: Lachmann B
Published By: Springer-Verlag1988 in Berlin, Germany

1988
Chapter Title: Multicenter randomized trial of surfactant replacement with calf lung surfactant extract (CLSE): Effects of pre- and post-ventilatory instillation and of multiple doses
Book Title: Surfactant replacement therapy in neonatal and adult respiratory distress syndro
Author List: Kendig JW, Notter RH, Davis J, Bartoletti A, Dweck HS, Risenberg HM, Cox C, Shapiro DL
Edited By: Lachmann B
Published By: Springer-Verlag1988 in Berlin, Germany

1987
Chapter Title: Adsorption of fetal lung liquid and exogenous surfactant in premature lambs
Book Title: Physiology of the fetal and neonatal lung
Author List: Egan EA, Kwong MS, Notter RH
Edited By: Walters DV, Strang LB, Gerbelle F
Published By: MTP Press, Ltd.1987 in Lancaster, England

1986
Chapter Title: Pulmonary surfactant effects in sublethal hyperoxic lung injury
Book Title: Oxygen radicals
Author List: Holm BA, Notter RH
Edited By: Taylor AE, Matalon S
Published By: APS Press1986 in Bethesda, MD

1986
Chapter Title: Biomedical examples of transport phenomena: Coupled diffusion effects
Book Title: CHEMI Modules
Author List: Notter RH
Edited By: Gordon, RJ
Published By: A.I.Ch.E. Press1986 in New York, NY

1986
Chapter Title: Biomedical examples of transport phenomena: facilitated diffusion
Book Title: CHEMI Modules
Author List: Notter RH
Edited By: Gordon RJ
Published By: A.I.Ch.E. Press1986 in New York, NY

1984
Chapter Title: Dynamic surface tension lowering by impaction of ultrasonically produced phospholipid aerosols at the air-water interface
Book Title: Aerosols: science, technology, and industrial applications of airborne particles
Author List: Wojciak JJ, Notter RH, Oberdoerster G
Edited By: Lia BYH, Pui DYH, Fissan H
Published By: Elsevier1984 in The Netherlands

1984
Chapter Title: Surface chemistry of pulmonary surfactant: Role of individual components
Book Title: Pulmonary surfactant
Author List: Notter RH
Edited By: Van Golde LMG, Robertson B, Batenburg JJ
Published By: Elsevier1984 in The Netherlands

1984
Book Title: are included in the Publications Section
Author List: Scientific peer-reviewed book chapters
Published By: - present1984