Skip to main content
Explore URMC

William H. Merigan, Jr., Ph.D.


Showing all 80 journal articles & 0 books available

Journal Articles

Godat T, Kohout K, Yang Q, Parkins K, McGregor JE, Merigan WH, Williams DR, Patterson SS. "Cone-Opponent Ganglion Cells in the Primate Fovea Tuned to Non-Cardinal Color Directions." bioRxiv : the preprint server for biology.. 2023 Sep 16; Epub 2023 Sep 16.

Godat T, Cottaris NP, Patterson S, Kohout K, Parkins K, Yang Q, Strazzeri JM, McGregor JE, Brainard DH, Merigan WH, Williams DR. "Contributed Session III: In vivo calcium imaging of macaque foveolar retinal ganglion cells reveals spatiochromatic receptive field properties." Journal of vision.. 2023 Sep 1; 23(11):32.

Godat T, Cottaris NP, Patterson S, Kohout K, Parkins K, Yang Q, Strazzeri JM, McGregor JE, Brainard DH, Merigan WH, Williams DR. "In vivo chromatic and spatial tuning of foveolar retinal ganglion cells in Macaca fascicularis." PloS one.. 2022 17(11):e0278261. Epub 2022 Nov 29.

McGregor JE, Kunala K, Xu Z, Murphy PJ, Godat T, Strazzeri JM, Bateman BA, Fischer WS, Parkins K, Chu CJ, Puthussery T, Williams DR, Merigan WH. "Optogenetic therapy restores retinal activity in primate for at least a year following photoreceptor ablation." Molecular therapy : the journal of the American Society of Gene Therapy.. 2021 Sep 18; Epub 2021 Sep 18.

Aboualizadeh E, Phillips MJ, McGregor JE, DiLoreto DA, Strazzeri JM, Dhakal KR, Bateman B, Jager LD, Nilles KL, Stuedemann SA, Ludwig AL, Hunter JJ, Merigan WH, Gamm DM, Williams DR. "Imaging Transplanted Photoreceptors in Living Nonhuman Primates with Single-Cell Resolution." Stem cell reports.. 2020 Jul 21; Epub 2020 Jul 21.

Dhakal KR, Walters S, McGregor JE, Schwarz C, Strazzeri JM, Aboualizadeh E, Bateman B, Huxlin KR, Hunter JJ, Williams DR, Merigan WH. "Localized Photoreceptor Ablation Using Femtosecond Pulses Focused With Adaptive Optics." Translational vision science & technology.. 2020 Jun; 9(7):16. Epub 2020 Jun 16.

Byrne LC, Day TP, Visel M, Strazzeri JA, Fortuny C, Dalkara D, Merigan WH, Schaffer DV, Flannery JG. "In vivo-directed evolution of adeno-associated virus in the primate retina." JCI insight.. 2020 May 21; 5(10)Epub 2020 May 21.

McGregor JE, Godat T, Dhakal KR, Parkins K, Strazzeri JM, Bateman BA, Fischer WS, Williams DR, Merigan WH. "Optogenetic restoration of retinal ganglion cell activity in the living primate." Nature communications.. 2020 Apr 3; 11(1):1703. Epub 2020 Apr 03.

Hunter JJ, Merigan WH, Schallek JB. "Imaging Retinal Activity in the Living Eye." Annual review of vision science.. 2019 Sep 15; 5:15-45.

Walters S, Schwarz C, Sharma R, Rossi EA, Fischer WS, DiLoreto DA, Strazzeri J, Nelidova D, Roska B, Hunter JJ, Williams DR, Merigan WH. "Cellular-scale evaluation of induced photoreceptor degeneration in the living primate eye." Biomedical optics express.. 2019 Jan 1; 10(1):66-82. Epub 2018 Dec 05.

McGregor JE, Williams DR, Merigan WH. "Functional Assessment of Vision Restoration." Advances in experimental medicine and biology.. 2019 1185:145-149.

Cheong SK, Strazzeri JM, Williams DR, Merigan WH. "All-optical recording and stimulation of retinal neurons in vivo in retinal degeneration mice." PloS one.. 2018 13(3):e0194947. Epub 2018 Mar 29.

Cheong SK, Xiong W, Strazzeri JM, Cepko CL, Williams DR, Merigan WH. "In Vivo Functional Imaging of Retinal Neurons Using Red and Green Fluorescent Calcium Indicators." Advances in experimental medicine and biology.. 2018 1074:135-144.

McGregor JE, Yin L, Yang Q, Godat T, Huynh KT, Zhang J, Williams DR, Merigan WH. "Functional architecture of the foveola revealed in the living primate." PloS one.. 2018 13(11):e0207102. Epub 2018 Nov 28.

Marcos S, Werner JS, Burns SA, Merigan WH, Artal P, Atchison DA, Hampson KM, Legras R, Lundstrom L, Yoon G, Carroll J, Choi SS, Doble N, Dubis AM, Dubra A, Elsner A, Jonnal R, Miller DT, Paques M, Smithson HE, Young LK, Zhang Y, Campbell M, Hunter J, Metha A, Palczewska G, Schallek J, Sincich LC. "Vision science and adaptive optics, the state of the field." Vision research.. 2017 Mar; 132:3-33. Epub 2017 Feb 27.

Kotterman MA, Yin L, Strazzeri JM, Flannery JG, Merigan WH, Schaffer DV. "Antibody neutralization poses a barrier to intravitreal adeno-associated viral vector gene delivery to non-human primates." Gene therapy.. 2015 Feb; 22(2):116-26. Epub 2014 Dec 11.

Yang Q, Yin L, Nozato K, Zhang J, Saito K, Merigan WH, Williams DR, Rossi EA. "Calibration-free sinusoidal rectification and uniform retinal irradiance in scanning light ophthalmoscopy." Optics letters.. 2015 Jan 1; 40(1):85-8.

Yin L, Masella B, Dalkara D, Zhang J, Flannery JG, Schaffer DV, Williams DR, Merigan WH. "Imaging light responses of foveal ganglion cells in the living macaque eye." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2014 May 7; 34(19):6596-605.

Strazzeri JM, Hunter JJ, Masella BD, Yin L, Fischer WS, Diloreto DA, Libby RT, Williams DR, Merigan WH. "Focal damage to macaque photoreceptors produces persistent visual loss." Experimental eye research.. 2014 Feb; 119:88-96. Epub 2013 Dec 05.

Dalkara D, Byrne LC, Klimczak RR, Visel M, Yin L, Merigan WH, Flannery JG, Schaffer DV. "In vivo-directed evolution of a new adeno-associated virus for therapeutic outer retinal gene delivery from the vitreous." Science translational medicine.. 2013 Jun 12; 5(189):189ra76.

Yin L, Geng Y, Osakada F, Sharma R, Cetin AH, Callaway EM, Williams DR, Merigan WH. "Imaging light responses of retinal ganglion cells in the living mouse eye." Journal of neurophysiology.. 2013 May; 109(9):2415-21. Epub 2013 Feb 13.

Sharma R, Yin L, Geng Y, Merigan WH, Palczewska G, Palczewski K, Williams DR, Hunter JJ. "In vivo two-photon imaging of the mouse retina." Biomedical optics express.. 2013 4(8):1285-93. Epub 2013 Jul 09.

Geng Y, Dubra A, Yin L, Merigan WH, Sharma R, Libby RT, Williams DR. "Adaptive optics retinal imaging in the living mouse eye." Biomedical optics express.. 2012 Apr 1; 3(4):715-34. Epub 2012 Mar 15.

Hunter JJ, Morgan JI, Merigan WH, Sliney DH, Sparrow JR, Williams DR. "The susceptibility of the retina to photochemical damage from visible light." Progress in retinal and eye research. 2012 Jan; 31(1):28-42. Epub 2011 Nov 10.

Yin L, Greenberg K, Hunter JJ, Dalkara D, Kolstad KD, Masella BD, Wolfe R, Visel M, Stone D, Libby RT, Diloreto D, Schaffer D, Flannery J, Williams DR, Merigan WH. "Intravitreal injection of AAV2 transduces macaque inner retina." Investigative ophthalmology & visual science.. 2011 Apr 25; 52(5):2775-83. Epub 2011 Apr 25.

Rossi EA, Chung M, Dubra A, Hunter JJ, Merigan WH, Williams DR. "Imaging retinal mosaics in the living eye." Eye.. 2011 Mar; 25(3):301-8.

Hunter JJ, Masella B, Dubra A, Sharma R, Yin L, Merigan WH, Palczewska G, Palczewski K, Williams DR. "Images of photoreceptors in living primate eyes using adaptive optics two-photon ophthalmoscopy." Biomedical optics express.. 2010 Dec 17; 2(1):139-48. Epub 2010 Dec 17.

Morgan JI, Hunter JJ, Merigan WH, Williams DR. "The reduction of retinal autofluorescence caused by light exposure." Investigative ophthalmology & visual science.. 2009 Dec; 50(12):6015-22. Epub 2009 Jul 23.

Scoles D, Gray DC, Hunter JJ, Wolfe R, Gee BP, Geng Y, Masella BD, Libby RT, Russell S, Williams DR, Merigan WH. "In-vivo imaging of retinal nerve fiber layer vasculature: imaging histology comparison." BMC ophthalmology.. 2009 Aug 23; 9:9. Epub 2009 Aug 23.

Morgan JI, Dubra A, Wolfe R, Merigan WH, Williams DR. "In vivo autofluorescence imaging of the human and macaque retinal pigment epithelial cell mosaic." Investigative ophthalmology & visual science.. 2009 Mar; 50(3):1350-9. Epub 2008 Oct 24.

Morgan JI, Hunter JJ, Masella B, Wolfe R, Gray DC, Merigan WH, Delori FC, Williams DR. "Light-induced retinal changes observed with high-resolution autofluorescence imaging of the retinal pigment epithelium." Investigative ophthalmology & visual science.. 2008 Aug; 49(8):3715-29. Epub 2008 Apr 11.

Gray DC, Wolfe R, Gee BP, Scoles D, Geng Y, Masella BD, Dubra A, Luque S, Williams DR, Merigan WH. "In vivo imaging of the fine structure of rhodamine-labeled macaque retinal ganglion cells." Investigative ophthalmology & visual science.. 2008 Jan; 49(1):467-73.

Hayes RD, Merigan WH. "Mechanisms of Sensitivity Loss due to Visual Cortex Lesions in Humans and Macaques." Cerebral cortex.. 2007 May; 17(5):1117-28. Epub 2006 Jun 12.

Merigan WH, Saunders RC. "Unilateral deficits in visual perception and learning after unilateral inferotemporal cortex lesions in macaques." Cerebral cortex.. 2004 Aug; 14(8):863-71. Epub 2004 Apr 27.

Shimozaki SS, Hayhoe MM, Zelinsky GJ, Weinstein A, Merigan WH, Ballard DH. "Effect of parietal lobe lesions on saccade targeting and spatial memory in a naturalistic visual search task." Neuropsychologia.. 2003 41(10):1365-86.

Huxlin KR, Saunders RC, Marchionini D, Pham HA, Merigan WH. "Perceptual deficits after lesions of inferotemporal cortex in macaques." Cerebral cortex.. 2000 Jul; 10(7):671-83.

Merigan WH. "Cortical area V4 is critical for certain texture discriminations, but this effect is not dependent on attention." Visual neuroscience.. 2000 17(6):949-58.

Merigan WH. "Sorting the wheat from the chaff in visual perception." Nature neuroscience.. 1999 Aug; 2(8):690-1.

Huxlin KR, Merigan WH. "Deficits in complex visual perception following unilateral temporal lobectomy." Journal of cognitive neuroscience.. 1998 May; 10(3):395-407.

Merigan WH, Pham HA. "V4 lesions in macaques affect both single- and multiple-viewpoint shape discriminations." Visual neuroscience.. 1998 15(2):359-67.

Merigan WH. "Basic visual capacities and shape discrimination after lesions of extrastriate area V4 in macaques." Visual neuroscience.. 1996 13(1):51-60.

Pasternak T, Merigan WH. "Motion perception following lesions of the superior temporal sulcus in the monkey." Cerebral cortex.. 1994 4(3):247-59.

Merigan WH, Nealey TA, Maunsell JH. "Visual effects of lesions of cortical area V2 in macaques." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 1993 Jul; 13(7):3180-91.

Merigan WH. "Colour vision: human V4?" Current biology : CB.. 1993 Apr 1; 3(4):226-9.

Merigan WH, Maunsell JH. "How parallel are the primate visual pathways?" Annual review of neuroscience.. 1993 16:369-402.

Lynch JJ, Silveira LC, Perry VH, Merigan WH. "Visual effects of damage to P ganglion cells in macaques." Visual neuroscience.. 1992 Jun; 8(6):575-83.

Merigan WH, Byrne CE, Maunsell JH. "Does primate motion perception depend on the magnocellular pathway?" The Journal of neuroscience : the official journal of the Society for Neuroscience.. 1991 Nov; 11(11):3422-9.

Merigan WH, Katz LM, Maunsell JH. "The effects of parvocellular lateral geniculate lesions on the acuity and contrast sensitivity of macaque monkeys." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 1991 Apr; 11(4):994-1001.

Merigan WH, Maunsell JH. "Macaque vision after magnocellular lateral geniculate lesions." Visual neuroscience.. 1990 Oct; 5(4):347-52.

Merigan WH, Katz LM. "Spatial resolution across the macaque retina." Vision research.. 1990 30(7):985-91.

Lynch JJ, Eskin TA, Merigan WH. "Selective degeneration of the parvocellular-projecting retinal ganglion cells in a New World monkey, Saimiri sciureus." Brain research.. 1989 Oct 16; 499(2):325-32.

Lynch JJ, Merigan WH, Eskin TA. "Subchronic dosing of macaques with 2,5-hexanedione causes long-lasting motor dysfunction but reversible visual loss." Toxicology and applied pharmacology.. 1989 Mar 15; 98(1):166-80.

Merigan WH. "Chromatic and achromatic vision of macaques: role of the P pathway." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 1989 Mar; 9(3):776-83.

Eskin TA, Merigan WH, Wood RW. "Carbon disulfide effects on the visual system. II. Retinogeniculate degeneration." Investigative ophthalmology & visual science.. 1988 Apr; 29(4):519-27.

Merigan WH, Wood RW, Zehl D, Eskin TA. "Carbon disulfide effects on the visual system. I. Visual thresholds and ophthalmoscopy." Investigative ophthalmology & visual science.. 1988 Apr; 29(4):512-8.

Eskin TA, Merigan WH. "Selective acrylamide-induced degeneration of color opponent ganglion cells in macaques." Brain research.. 1986 Jul 23; 378(2):379-84.

Merigan WH, Eskin TA. "Spatio-temporal vision of macaques with severe loss of P beta retinal ganglion cells." Vision research.. 1986 26(11):1751-61.

Pasternak T, Flood DG, Eskin TA, Merigan WH. "Selective damage to large cells in the cat retinogeniculate pathway by 2,5-hexanedione." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 1985 Jun; 5(6):1641-52.

Merigan WH, Barkdoll E, Maurissen JP, Eskin TA, Lapham LW. "Acrylamide effects on the macaque visual system. I. Psychophysics and electrophysiology." Investigative ophthalmology & visual science.. 1985 Mar; 26(3):309-16.

Eskin TA, Lapham LW, Maurissen JP, Merigan WH. "Acrylamide effects on the macaque visual system. II. Retinogeniculate morphology." Investigative ophthalmology & visual science.. 1985 Mar; 26(3):317-29.

Merigan WH, Wood RW, Zehl DN. "Recent observations on the neurobehavioral toxicity of carbon disulfide." Neurotoxicology.. 1985 6(4):81-8.

Pasternak T, Merigan WH. "Effects of stimulus speed on direction discriminations." Vision research.. 1984 24(10):1349-55.

Weiss B, Wood RW, Merigan WH. "Toxicity evaluation needs the intact animal." Annals of the New York Academy of Sciences.. 1983 406:82-91.

Pasternak T, Merigan WH, Flood DG, Zehl D. "The role of area centralis in the spatial vision of the cat." Vision research.. 1983 23(12):1409-16.

Merigan WH, Maurissen JP, Weiss B, Eskin T, Lapham LW. "Neurotoxic actions of methylmercury on the primate visual system." Neurobehavioral toxicology and teratology. 1983 5(6):649-58.

Merigan WH, Barkdoll E, Maurissen JP. "Acrylamide-induced visual impairment in primates." Toxicology and applied pharmacology.. 1982 Feb; 62(2):342-5.

Pasternak T, Movshon JA, Merigan WH. "Creation of direction selectivity in adult strobe-reared cats." Nature.. 1981 Aug 27; 292(5826):834-6.

Pasternak T, Merigan WH, Movshon JA. "Motion mechanisms in strobe-reared cats: psychophysical and electrophysical measures." Acta psychologica.. 1981 Aug; 48(1-3):321-32.

Merigan WH, Pasternak T, Zehl D. "Spatial and temporal vision of macaques after central retinal lesions." Investigative ophthalmology & visual science.. 1981 Jul; 21(1 Pt 1):17-26.

Pasternak T, Merigan WH. "The luminance dependence of spatial vision in the cat." Vision research.. 1981 21(9):1333-9.

Pasternak T, Merigan WH. "Movement detection by cats: invariance with direction and target configuration." Journal of comparative and physiological psychology.. 1980 Oct; 94(5):943-52.

Merigan WH. "Temporal modulation sensitivity of macaque monkeys." Vision research.. 1980 20(11):953-9.

Pasternak T, Merigan WH. "Abnormal visual resolution of cats reared in stroboscopic illumination." Nature.. 1979 Jul 26; 280(5720):313-4.

Merigan WH. "Effects of toxicants on visual systems." Neurobehavioral toxicology. 1979 1 Suppl 1:15-22.

Laties VG, Merigan WH. "Behavioral effects of carbon monoxide on animals and man." Annual review of pharmacology and toxicology.. 1979 19:357-92.

Smith MD, Merigan WH, Mcintire RW. "Effects of carbon monoxide on fixed-consecutive-number performance in rats." Pharmacology, biochemistry, and behavior.. 1976 Sep; 5(3):257-62.

Ator NA, Merigan WH, McIntire RW. "The effects of brief exposures to carbon monoxide on temporally differentiated responding." Environmental research.. 1976 Aug; 12(1):75-80.

Merigan WH, McIntire RW. "Effects of carbon monoxide on responding under a progressive ratio schedule in rats." Physiology & behavior.. 1976 Apr; 16(4):407-12.

Merigan WH. "The contrast sensitivity of the squirrel monkey (Saimiri sciureus)." Vision research.. 1976 16(4):375-9.

Merigan WH, Miller JS, Gollub LR. "Short-component multiple schedules: effects of relative reinforcement duration." Journal of the experimental analysis of behavior.. 1975 Sep; 24(2):183-9.