Nicholas Jospe, M.D.

Nicholas Jospe, M.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 777
Rochester, NY 14642

Office: (585) 275-7744
Fax: (585) 244-6097

Journal Articles

Showing all 35 journal articles available.

2016 Jan 1
Kryvalap Y, Lo CW, Manuylova E, Baldzizhar R, Jospe N, Czyzyk J. "Antibody Response to Serpin B13 Induces Adaptive Changes in Mouse Pancreatic Islets and Slows Down the Decline in the Residual Beta Cell Function in Children with Recent Onset of Type 1 Diabetes Mellitus." The Journal of biological chemistry. 2016 Jan 1; 291(1):266-78. Epub 2015 Nov 17.
2014
Durinovic-Belló I, Gersuk VH, Ni C, Wu R, Thorpe J, Jospe N, Sanda S, Greenbaum CJ, Nepom GT. "Avidity-dependent programming of autoreactive T cells in T1D." PloS one. 2014 9(5):e98074. Epub 2014 May 20.
2011 Nov
Mallone R, Scotto M, Janicki CN, James EA, Fitzgerald-Miller L, Wagner R, Gottlieb P, Thorpe J, Jospe N, Durinovic-Bellò I, Boitard C, Lou O, Dayan CM, Wong FS, . "Immunology of Diabetes Society T-Cell Workshop: HLA class I tetramer-directed epitope validation initiative T-Cell Workshop Report-HLA Class I Tetramer Validation Initiative." Diabetes/metabolism research and reviews. 2011 Nov; 27(8):720-6.
2011 Nov
James EA, Mallone R, Schloot NC, Gagnerault MC, Thorpe J, Fitzgerald-Miller L, Reichow J, Wagner R, Pham MN, Jospe N, Lou O, Gottlieb PA, Brooks-Worrell BM, Durinovic-Belló I, . "Immunology of Diabetes Society T-Cell Workshop: HLA class II tetramer-directed epitope validation initiative." Diabetes/metabolism research and reviews. 2011 Nov; 27(8):727-36.
2011 Aug
Hughson A, Bromberg I, Johnson B, Quataert S, Jospe N, Fowell DJ. "Uncoupling of proliferation and cytokines from suppression within the CD4+CD25+Foxp3+ T-cell compartment in the 1st year of human type 1 diabetes." Diabetes. 2011 Aug; 60(8):2125-33. Epub 2011 Jun 29.
2005 Jul
Skyler JS, Weinstock RS, Raskin P, Yale JF, Barrett E, Gerich JE, Gerstein HC, . "Use of inhaled insulin in a basal/bolus insulin regimen in type 1 diabetic subjects: a 6-month, randomized, comparative trial." Diabetes care. 2005 Jul; 28(7):1630-5.
2005 May
Skyler JS, Krischer JP, Wolfsdorf J, Cowie C, Palmer JP, Greenbaum C, Cuthbertson D, Rafkin-Mervis LE, Chase HP, Leschek E. "Effects of oral insulin in relatives of patients with type 1 diabetes: The Diabetes Prevention Trial--Type 1." Diabetes care. 2005 May; 28(5):1068-76.
2005 Mar
Mack-Fogg JE, Orlowski CC, Jospe N. "Continuous subcutaneous insulin infusion in toddlers and children with type 1 diabetes mellitus is safe and effective." Pediatric diabetes. 2005 Mar; 6(1):17-21.
2004 Nov
Jospe N, Florence M. "Hermaphroditus in Greco-Roman myth: lessons and hypotheses for intersex today." Journal of pediatric endocrinology & metabolism : JPEM. 2004 Nov; 17(11):1471-9.
2004
Epstein RM, Dannefer EF, Nofziger AC, Hansen JT, Schultz SH, Jospe N, Connard LW, Meldrum SC, Henson LC. "Comprehensive assessment of professional competence: the Rochester experiment." Teaching and learning in medicine. 2004 16(2):186-96.
2002 May 30
. "Effects of insulin in relatives of patients with type 1 diabetes mellitus." The New England journal of medicine. 2002 May 30; 346(22):1685-91.
2001 Aug
Yu L, Cuthbertson DD, Maclaren N, Jackson R, Palmer JP, Orban T, Eisenbarth GS, Krischer JP, . "Expression of GAD65 and islet cell antibody (ICA512) autoantibodies among cytoplasmic ICA+ relatives is associated with eligibility for the Diabetes Prevention Trial-Type 1." Diabetes. 2001 Aug; 50(8):1735-40.
2001 May
Jospe N, Kaplowitz PB, McCurdy FA, Gottlieb RP, Harris MA, Boyle R. "Third-year medical student survey of office preceptorships during the pediatric clerkship." Archives of pediatrics & adolescent medicine. 2001 May; 155(5):592-6.
2001 Feb
Chase HP, Cuthbertson DD, Dolan LM, Kaufman F, Krischer JP, Schatz DA, White NH, Wilson DM, Wolfsdorf J. "First-phase insulin release during the intravenous glucose tolerance test as a risk factor for type 1 diabetes." The Journal of pediatrics. 2001 Feb; 138(2):244-9.
2001 Feb
Greenbaum CJ, Cuthbertson D, Krischer JP, . "Type I diabetes manifested solely by 2-h oral glucose tolerance test criteria." Diabetes. 2001 Feb; 50(2):470-6.
2000 Mar
Greenbaum CJ, Schatz DA, Cuthbertson D, Zeidler A, Eisenbarth GS, Krischer JP, The Diabetes Prevention TrialType 1 Study Group [Jospe N  Study Group Member]. "Islet Cell Antibody-Positive Relatives With Human Leukocyte Antigen DQA1*0102, DQB1*0602: Identification by the Diabetes Prevention Trial-Type 1". Journal of Clinical Endocrinology & Metabolism. 2000; 85((3)): 1255-1260. Link
2000
Gupta P, Mick G, Fong CT, Jospe N, McCormick K. "Hyponatremia secondary to reset osmostat in a child with a central nervous system midline defect and a chromosomal abnormality." Journal of pediatric endocrinology & metabolism : JPEM. 2000 13(9):1637-41.
1999 Jun
Jospe N, Lane A, Greenlaw J, Sulkes SB. "Ambiguity of the external genitalia in an infant with Down syndrome: gender assignment and ethical implications." Mental retardation. 1999 Jun; 37(3):232-6.
1996 Nov
Jospe N, Forbes G. "Fluids and electrolytes--clinical aspects." Pediatrics in review. 1996 Nov; 17(11):395-403; quiz 404.
1996 Aug
Jospe N, Kaplowitz PB, Furlanetto RW. "Homozygous nonsense mutation in the insulin receptor gene of a patient with severe congenital insulin resistance: leprechaunism and the role of the insulin-like growth factor receptor." Clinical endocrinology. 1996 Aug; 45(2):229-35.
1995 Dec
DPT-1 Study Group; [Jospe N - Study Group Member]. "The Diabetes Prevention Trial-Type 1 Diabetes (DPT-1): Implementation of Screening and Staging of Relatives". Transplantation Proceedings (Diabetes Prevention Trial- type 1 Study Group References). 1995; 27((6)): 3377. Link
1995 Jan 6
Liu R, Zhu J, Jospe N, Furlanetto RW, Bastian W, Livingston JN. "Deletion of lysine 121 creates a temperature-sensitive alteration in insulin binding by the insulin receptor." The Journal of biological chemistry. 1995 Jan 6; 270(1):476-82.
1995
Jospe N, Orlowski CC, Furlanetto RW. "Comparison of transdermal and oral estrogen therapy in girls with Turner's syndrome." Journal of pediatric endocrinology & metabolism : JPEM. 1995 8(2):111-6.
1994 Nov
Jospe N, Zhu J, Liu R, Livingston JN, Furlanetto RW. "Deletion of 3 basepairs resulting in the loss of lysine-121 in the insulin receptor alpha-subunit in a patient with leprechaunism: binding, phosphorylation, and biological activity." The Journal of clinical endocrinology and metabolism. 1994 Nov; 79(5):1294-302.
1994 Jun
Becker B, Jospe N, Goldsmith LA. "Melanocytic nevi in Turner syndrome." Pediatric dermatology. 1994 Jun; 11(2):120-4.
1993 Mar
Sandrini R, Jospe N, Migeon CJ. "Temporal and individual variations in the dose of glucocorticoid used for the treatment of salt-losing congenital virilizing adrenal hyperplasia due to 21-hydroxylase deficiency." Acta paediatrica (Oslo, Norway : 1992). Supplement. 1993 Mar; 388:56-60; discussion 61.
1991
Sherer, D.M., Jospe, N., Abramowicz, J.S. "Steroid, 21-Hydroxylase". The Fetus. 1991; 1(5): 1-4. Link
1990 Aug
Jospe N, Powell KR. "Growth hormone deficiency in an 8-year-old girl with human immunodeficiency virus infection." Pediatrics. 1990 Aug; 86(2):309-12.
1989 Oct
Donohoue PA, Jospe N, Migeon CJ, Van Dop C. "Two distinct areas of unequal crossingover within the steroid 21-hydroxylase genes produce absence of CYP21B." Genomics. 1989 Oct; 5(3):397-406.
1988 Feb
Jospe N, Berkovitz GD, Corcoran LE, Humphrey RL. "Factitious transient neonatal hyperthyrotropinemia." Journal of endocrinological investigation. 1988 Feb; 11(2):129-32.
1988 Jan
McLean RH, Donohoue PA, Jospe N, Bias WB, Van Dop C, Migeon CJ. "Restriction fragment analysis of duplication of the fourth component of complement (C4A)." Genomics. 1988 Jan; 2(1):76-85.
1987 Feb 13
Jospe N, Donohoue PA, Van Dop C, McLean RH, Bias WB, Migeon CJ. "Prevalence of polymorphic 21-hydroxylase gene (CA21HB) mutations in salt-losing congenital adrenal hyperplasia." Biochemical and biophysical research communications. 1987 Feb 13; 142(3):798-804.
1986 Apr 29
Donohoue PA, Jospe N, Migeon CJ, McLean RH, Bias WB, White PC, Van Dop C. "Restriction maps and restriction fragment length polymorphisms of the human 21-hydroxylase genes." Biochemical and biophysical research communications. 1986 Apr 29; 136(2):722-9.
1986
Donohoue PA, Van Dop C, Jospe N, Migeon CJ. "Congenital adrenal hyperplasia: molecular mechanisms resulting in 21-hydroxylase deficiency." Acta endocrinologica. Supplementum. 1986 279:315-20.
0
Hughson, Angela; Bromberg, Irena; Johnson, Barbara; Fowell, Deborah PhD; Jospe, Nicholas MD. "Progressive Loss of Regulatory T cell Function in the first year from Diagnosis in Children with Type 1 Diabetes Mellitus.".

Books

2015
Svoren B, Jospe N. "Section on Diabetes". Nelson Textbook of Pediatric. Kliegman RM,. Philadelphia, PA: Elsevier, 2015. 2760-90
2015
McInerny, T. "Hyperthyroidism". Textbook of Pediatric Care. St. Louis: Mosby Year Book Publishers, 2015.
2015
Weber D, Jospe N. Disorders of Pre pubertal breast development and abnormalities for periFACTS ob/gyn Academy,. : Online Journal, 2015.
2011
McInerny,T. "Hyperthyroidism". Textbook of Pediatric Care. St. Louis: Mosby Year Book Publishers, 2011.
2009
Jospe N. "Endocrinology". Nelson Essentials Sixth Edition. Philadelphia, PA: Elsevier, Inc, 2009.
2008
Jospe, Nicholas MD. "Endocrine and Metabolic Disorders". The Merck Manual of Medical Information. Rahway, NJ: Beers, MH, 2008.
2008
Jospe, Nichoals MD. "Section on Endocrinology". Nelson Essenttials of Pediatrics. Philadelphia, PA: W. B. Saunders, 2008.
2008
Jospe N. "Metabolic, Electrolyte, and Toxic Disorders in Neonates.". Merck Manual Edition 19. Rahway, NJ: Merck Publishing Group, 2008.
2007
Jospe N. "Endocrinology (in preparation)". Pediatric Clerkship Guide: Essential Guide to the Pediatric Clerkship. Woodhead JC. St. Louis, MO: Mosby, 2007.
2007
Jospe, N. "Endocrine and Metabolic Disorders: Pediatric Diabetes". The Merk Manual of Medical Infomation-Home Edition. Rahway, NJ: Merk Research Laboratories, 2007.
2007
Jospe N. "Diabetes Mellitus type 1". Mosby's Pediatric Clinical Advisor. Garfunkel, Christy, Kaczarowski.. St Louis, MO: Harcourt, Health Sciences, 2007. 163-164
2007
Jospe N. "Diabetes Mellitus type 2". Mosby's Pediatric Clinical Advisor. Garfunkel, Christy, Kaczarowski. St Louis, MO: Harcourt, Health Sciences, 2007. 165-166
2007
Jospe N. "Diabetic ketoacidosis". Mosby's Pediatric Clinical Advisor. Garfunkel, Christy, Kaczarowski. St Louis, MO: Harcourt, Health Sciences, 2007. 167-168
2007
Jospe N. "Diabetes in Childhood and Adolescence". The Merck Manual of Medical Information. Beers MH (1st Editor). Rahway, NJ: Merck and Company, 2007.
2006
Jospe N. "Hyperthyroidism (in preparation)". Primary Pediatric Care. McInerny T, et al. St. Louis, MO: Mosby Year Book Publishers, 2006.
2005
Jospe N. "Endocrine and Metabolic Disorders". The Merck Manual of Medical Information. Beers MH (1st Editor). Rahway, NJ: Merck and Company, 2005.
2005
Jospe N. Computer-assisted Learning in Pediatrics Project. LH Fall, A Olson, NB Berman. Dartmouth, NH: CLIPP, 2005.
2005
Jospe N. "Section on Endocrinology". Nelson Essentials of Pediatrics. Philadelphia, PA: W.B. Saunders, 2005. 771-824
2005
Jospe N. "Ambiguous Genitalia". Mosby's Pediatric Clinical Advisor. Garfunkel, Christy, Kaczarowski. St Louis, MO: Harcourt, Health Sciences, 2005. 21-22
2004
Jospe N. "Disorders of Puberty". Pediatrics. Osborn, Dewitt, First, Zenel. Columbus, OH: McGraw-Hill Companies, 2004. 10172-11023
2004
Jospe N. "Disorders of Sexual Differentiation". Pediatrics. Osborn, Dewitt, First, Zenel. Columbus, OH: McGraw-Hill Companies, 2004. 1023-1025
2004
Jospe N. "Disorders of the Adrenal Gland". Pediatrics. Osborn, Dewitt, First, Zenel. Columbus, OH: McGraw-Hill Companies, 2004. 1031-1039
2003
Jospe N. "Endocrinology". Pediatric Clerkship Guide: Essential Guide to the Pediatric Clerkship. Woodhead JC. St Louis, MO: Mosby, 2003. 468-480
2003
Jospe N. "Growth problems". Pediatric Clerkship Guide: Essential Guide to the Pediatric Clerkship. Woodhead JC. St Louis, MO: Mosby, 2003. 257-265
2001
Jospe N. "Ambiguous Genitalia". Mosby's Pediatric Clinical Advisor. Garfunkel, Christy, Kaczaroswski. St Louis, MO: Harcourt, Health Sciences, 2001. 138-140
2001
Jospe N. "Diabetes Mellitus type 1". Mosby's Pediatric Clinical Advisor. Garfunkel, Christy, Kaczaroswski. St Louis, MO: Harcourt, Health Sciences, 2001. 283-285
2001
Jospe N. "Diabetes Mellitus type 2". Mosby's Pediatric Clinical Advisor. Garfunkel, Christy, Kaczaroswski. St Louis, MO: Harcourt, Health Sciences, 2001. 285-287
2001
Jospe N. "Diabetic ketoacidosis". Mosby's Pediatric Clinical Advisor. Garfunkel, Christy, Kaczaroswski.. St Louis, MO: Harcourt, Health Sciences, 2001. 287-289
2001
Jospe N. "Hyperthyroidism". Primary Pediatric Care. Hoekelman R, et al. St. Louis, MO: Mosby Year Book Publishers, 2001. 1554-1557
1997
Jospe N. "Hyperthyroidism". Primary Pediatric Care. Hoekelman R, et al. St. Louis, MO: Mosby Year Book Publishers, 1997. 1351-1354
1997
Jospe N. "The Merck Manual of Medical Information - Home Edition". Endocrine and Metabolic Disorders. Berkow R (1st Editor). Rahway, NJ: Merck and Company, 1997.
1997
Jospe N. "Endocrine Disorders". The Merck Manual of Medical Information. Berkow R (1st Editor). Rahway, NJ: Merck and Company, 1997.
1996
Jospe N (contributing editor). "Pediatric Endocrinology". The Rochester Manual: practical patient Care, Medicine, Surgery, Pediatrics, OB-. Illig and Husser. Cedar Grove, NJ: Laennec Publishing, Inc., 1996. 428-436