Patricia J. Simpson-Haidaris, Ph.D.

Patricia J. Simpson-Haidaris, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 610
Rochester, NY 14642

Research Bio

The role of fibrinogen in the pathogenesis of disease progression and resolution in the lung, the vasculature, and in prostate and breast carcinoma.

Awards & Honors (Local)

Miles Inc., Post-doctoral Fellowship (Salary and Supplies) 1981
American Society for Microbiology Garner Award for Oral Presentation 1980
Miles Inc., Pre-doctoral Fellowship (Stipend and Tuition) 1979 - 1981
Indiana University Merit Scholarship 1970 - 1973

Recent Journal Articles

Showing the 5 most recent journal articles. 72 available »

2017 Jan 2
Freires IA, Avilés-Reyes A, Kitten T, Simpson-Haidaris PJ, Swartz M, Knight PA, Rosalen PL, Lemos JA, Abranches J. "Heterologous expression of Streptococcus mutans Cnm in Lactococcus lactis promotes intracellular invasion, adhesion to human cardiac tissues and virulence." Virulence. 2017 Jan 2; 8(1):18-29. Epub 2016 Jun 03.
2014 Feb
Avilés-Reyes A, Miller JH, Simpson-Haidaris PJ, Lemos JA, Abranches J. "Cnm is a major virulence factor of invasive Streptococcus mutans and part of a conserved three-gene locus." Molecular oral microbiology. 2014 Feb; 29(1):11-23. Epub 2013 Oct 30.
2011 Jun
Abranches J, Miller JH, Martinez AR, Simpson-Haidaris PJ, Burne RA, Lemos JA. "The collagen-binding protein Cnm is required for Streptococcus mutans adherence to and intracellular invasion of human coronary artery endothelial cells." Infection and immunity. 2011 Jun; 79(6):2277-84. Epub 2011 Mar 21.
2010 Nov
Simpson-Haidaris PJ, Seweryniak KE, Spinelli SL, Garcia-Bates TM, Murant TI, Pollock SJ, Sime PJ, Phipps RP. "A putative role for platelet-derived PPAR? in vascular homeostasis demonstrated by anti-PPAR? induction of bleeding, thrombocytopenia and compensatory megakaryocytopoiesis." Journal of biotechnology. 2010 Nov; 150(3):417-27. Epub 2010 Oct 01.
2010 Mar 2
Simpson-Haidaris PJ, Sahni A. "Fibrin-specific beta(15-42) domain is exposed in cell-associated intact fibrinogen: Response to Weijers et al comment on the study by A. Sahni et al." International journal of cancer. 2010 Mar 2; Epub 2010 Mar 02.

Current Appointments

Associate Professor - Department of Medicine, Hematology/Oncology (SMD) - Primary


Certificate | Deaf Studies | Rochester Institute of Technology2000
PhD | Microbiology | University of Notre Dame1981
MS | Microbiology | University of Notre Dame1980
BA, double major | Chemistry & Biology | Indiana University1973

Post-Doctoral Training & Residency

Post-doctoral Fellow. Dept of Microbiology and Immunology, University of North Carolina. Research Mentor: Kenneth Bott, Ph.D.: "Molecular cloning and expression in prokaryotes. 0
Graduate Research Assistant, Dept of Microbiology, University of Notre Dame. Dissertation research performed under the direction of Dr. Charles Kulpa. Ph.D. Thesis: "Characterization and evaluation of large unilamellar liposomes as carriers of synthetic, single-stranded polyribonucleotides to affect RNA virus replication in culture. 1981
Associate Development Scientist: Miles, Inc., Ames Division. Developed and implemented quality assurance control systems to define quality of new products from raw materials through in-process production, finished product and clinical trials following GMP, GLP and FDA regulations for new clinical diagnostic products in immunochemistry test systems. 1979
Assistant Development Scientist: Miles Inc., Ames Division. Developed quality assurance control systems to define quality of new products for thyroid function, hepatitis B and urine chemistry test systems. Elkhart, IN 46515 1976