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Carl T. D'Angio, M.D.

Contact Information

Phone Numbers

Office: (585) 275-2972

Fax: (585) 461-3614

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

assignmentAccepting New Patients

Faculty Appointments

Patient Care Setting



Dr. D'Angio is Chief of the Division of Neonatology. He is an attending neonatologist at both URMC and Rochester General Hospital. In collaboration with other members of the neonatal team, he strives to provide compassionate, cutting-edge medical care to at-risk or critically ill newborns. Dr. D'Angio's particular clinical interests are infection and immunity in the newborn and the prevention of lung injury.

Professional Background

Dr. D’Angio attended medical school at Johns Hopkins University and received his Pediatric training at the Children’s Hospital of Philadelphia before arriving in Rochester in 1991 to complete a Fellowship in Neonatal-Perinatal Medicine. He has been a member of the University of Rochester faculty since 1994.


Dr. D'Angio's research focuses on clinical trials of therapies in the newborn. He is principal investigator for a combined University of Rochester-University of Buffalo site in the NICHD Neonatal Research Network, a 15-center consortium performing research in newborns. He has particular interest in immunizations and infections in the premature infant, lung injury, prevention of catheter-related infections, neonatal outcomes and clinical and research ethics.



  • Neonatal-Perinatal Medicine - American Board of Pediatrics
  • Pediatrics - American Board of Pediatrics


MD | Johns Hopkins University School of Medicine, Office of Registrar

Post-doctoral Training & Residency

07/01/1991 - 06/30/1994
Fellowship in Neonatology at University of Rochester Medical Center

07/01/1985 - 06/30/1987
Residency in Pediatrics at Children's Hospital of Philadelphia

07/01/1984 - 06/30/1985
Internship in Pediatrics at Children's Hospital of Philadelphia

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2011 - 2012
America's Top Doctors

2009 - 2010
Who's Who in Medicine and Healthcare

America's Top Doctors

2008 - 2009
Who's Who in America

2007 - 2010
Guide to America's Top Pediatricians

2004 - 2010
Best Doctors in America

1999 - 2000
Buswell Fellowship Award, University of Rochester

Bicentennial Unit Commendation, US Public Health Service

The PHS Citation, US Public Health Service

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Clinical Trials

A Randomized Trial of Targeted Temperature Management With Whole Body Hypothermia For Moderate And Severe Hypoxic-Ischemic Encephalopathy In Premature Infants 33-35 Weeks Gestational Age.

Lead Researcher: Carl T D'Angio

Encephalopathy is a general term that means brain disease, damage, or malfunction. This study is a randomized, controlled trial to assess safety and effectiveness of whole body hypothermia for 72 hours in preterm infants 33-35 weeks gestational age (GA) who present at <6 hours postnatal age with moderate to severe neonatal encephalopathy (NE). The study will enroll infants with signs of NE at 18 NICHD Neonatal Research Network sites, and randomly assign them to either receive hypothermia or participate in a non-cooled control group.

View Study Details

A Randomized Controlled Trial of the Effect Of Hydrocortisone on Survival Without Bronchopulmonary Dysplasia and on Neurodevelopmental Outcomes at 22 - 26 Months of Age in Intubated Infants < 30 Weeks Gestation Age

Lead Researcher: Carl T D'Angio

The Hydrocortisone and Extubation study will test if giving hydrocortisone for 10 days improves survival for premature infants who have a breathing tube. Infants will either receive hydrocortisone or placebo.

View Study Details


Journal Articles

Dadiz R, Nair J, D'Angio CT, Ryan RM, Lakshminrusimha S. "Methemoglobin and the response to inhaled nitric oxide in persistent pulmonary hypertension of the newborn." . 2019 Nov 11; Epub 2019 Nov 11.

McGowan EC, Laptook AR, Lowe J, Peralta-Carcelen M, Chowdhury D, Higgins RD, Hintz SR, Vohr BR, . "Developmental Outcomes of Extremely Preterm Infants with a Need for Child Protective Services Supervision." The Journal of pediatrics.. 2019 Sep 6; Epub 2019 Sep 06.

Edwards L, Cotten CM, Smith PB, Goldberg R, Saha S, Das A, Laptook AR, Stoll BJ, Bell EF, Carlo WA, D'Angio CT, DeMauro SB, Sanchez PJ, Shankaran S, Van Meurs KP, Vohr BR, Walsh MC, Malcolm WF, . "Inadequate oral feeding as a barrier to discharge in moderately preterm infants." Journal of perinatology : official journal of the California Perinatal Association.. 2019 Sep 0; 39(9):1219-1228. Epub 2019 Jul 11.

Books & Chapters

Chapter Title: Burden of Chronic Lung Disease on the Care-Givers: Families, Nurses, and Physicians
Book Title: Updates on Neonatal Chronic Lung Disease
Author List: Chiafery MC, D'Angio CT.
Edited By: Kallapur SG
Published By: Elsevier 2019

Chapter Title: Perinatal Ethics
Book Title: Perinatal Palliative Care: A Clinical Guide
Author List: Wax J, D'Angio CT, Chiafery MC.
Edited By: Denney-Koelsch E, Cote-Arsenault D.
Published By: Springer 2019 in New York

Chapter Title: Biostatistics in Research
Book Title: Avery's Neonatology Review
Author List: D'Angio CT.
Edited By: Chess PR.
Published By: Elsevier 2019 in New York