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Carl T. D'Angio, M.D.

Contact Information

Phone Numbers

Office: (585) 275-2972

Fax: (585) 461-3614

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

assignmentAccepting New Patients

Faculty Appointments

Patient Care Setting



Dr. D'Angio is Chief of the Division of Neonatology. He is an attending neonatologist at both URMC and Rochester General Hospital. In collaboration with other members of the neonatal team, he strives to provide compassionate, cutting-edge medical care to at-risk or critically ill newborns. Dr. D'Angio's particular clinical interests are infection and immunity in the newborn and the prevention of lung injury.

Professional Background

Dr. D’Angio attended medical school at Johns Hopkins University and received his Pediatric training at the Children’s Hospital of Philadelphia before arriving in Rochester in 1991 to complete a Fellowship in Neonatal-Perinatal Medicine. He has been a member of the University of Rochester faculty since 1994.


Dr. D'Angio's research focuses on clinical trials of therapies in the newborn. He is principal investigator for a combined University of Rochester-University of Buffalo site in the NICHD Neonatal Research Network, a 15-center consortium performing research in newborns. He has particular interest in immunizations and infections in the premature infant, lung injury, prevention of catheter-related infections, neonatal outcomes and clinical and research ethics.



MD | Johns Hopkins University School of Medicine (USA)

Post-doctoral Training & Residency

07/01/1991 - 06/30/1994
Fellowship in Neonatology at University of Rochester Medical Center

07/01/1985 - 06/30/1987
Residency in Pediatrics at Children's Hospital of Philadelphia

07/01/1984 - 06/30/1985
Internship in Pediatrics at Children's Hospital of Philadelphia

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2011 - 2012
America's Top Doctors

2009 - 2010
Who's Who in Medicine and Healthcare

America's Top Doctors

2008 - 2009
Who's Who in America

2007 - 2010
Guide to America's Top Pediatricians

2004 - 2010
Best Doctors in America

1999 - 2000
Buswell Fellowship Award, University of Rochester

Bicentennial Unit Commendation, US Public Health Service

The PHS Citation, US Public Health Service

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Clinical Trials

Management of the Patent Ductus Arteriosus in Premature Infants Trial (PDA Trial)

Lead Researcher: Carl T D'angio

Patent ductus arteriosus (PDA) is an extra blood vessel found in babies before birth and just after birth. In most babies who have an otherwise normal heart, the PDA will shrink and close on its own in the first few days of life. If it stays open longer, it may cause extra blood to flow to the lungs. This study estimates the risks and benefits of active treatment versus expectant management of premature babies with patent ductus arteriosus.

View Study Details

A Randomized Controlled Trial of the Effect Of Hydrocortisone on Survival Without Bronchopulmonary Dysplasia and on Neurodevelopmental Outcomes at 22 - 26 Months of Age in Intubated Infants < 30 Weeks Gestation Age

Lead Researcher: Carl T D'angio

The Hydrocortisone and Extubation study will test if giving hydrocortisone for 10 days improves survival for premature infants who have a breathing tube. Infants will either receive hydrocortisone or placebo.

View Study Details


Journal Articles

Chock VY, Smith E, Tan S, Ball MB, Das A, Hintz SR, Kirpalani H, Bell EF, Chalak LF, Carlo WA, Cotten CM, Widness JA, Kennedy KA, Ohls RK, Seabrook RB, Patel RM, Laptook AR, Mancini T, Sokol GM, Walsh MC, Yoder BA, Poindexter BB, Chawla S, D'Angio CT, Higgins RD, Van Meurs KP, . "Early brain and abdominal oxygenation in extremely low birth weight infants." Pediatric research.. 2022 May 5; Epub 2022 May 05.

Bell EF, Hintz SR, Hansen NI, Bann CM, Wyckoff MH, DeMauro SB, Walsh MC, Vohr BR, Stoll BJ, Carlo WA, Van Meurs KP, Rysavy MA, Patel RM, Merhar SL, Sánchez PJ, Laptook AR, Hibbs AM, Cotten CM, D'Angio CT, Winter S, Fuller J, Das A, . "Mortality, In-Hospital Morbidity, Care Practices, and 2-Year Outcomes for Extremely Preterm Infants in the US, 2013-2018." JAMA.. 2022 Jan 18; 327(3):248-263.

Gentle SJ, Carper B, Laughon MM, Jensen EA, Williams A, Travers CP, Ambalavanan N, Lal CV, Carlo WA, , Polin RA, Laptook AR, Keszler M, Hensman AM, Vieira E, Little E, Pierre LS, Walsh MC, Hibbs AM, Newman NS, Truog WE, Pallotto EK, Kilbride HW, Gauldin C, Holmes A, Johnson K, Parimi PS, Gaetano L, Poindexter BB, Schibler K, Merhar SL, Alexander B, Grisby C, Kirker K, Cotten CM, Goldberg RN, Finkle J, Fisher KA, Bose CL, Bernhardt J, Bose G, Clark C, Kicklighter SD, Rhodes-Ryan G, White D, Carlton DP, Stoll BJ, Patel RM, Loggins Y, Hale EC, Bottcher DI, Mackie C, Bremer AA, Higgins RD, Archer SW, Sokol GM, Herron DE, Joyce J, Tyson JE, Khan AM, Kennedy KA, Eason E, Stephens EK, McDavid GE, Arldt-McAlister J, Burson K, Garcia C, Hall D, Martin K, Martin SC, Rodgers S, Tate PLP, Wright SL, Sánchez PJ, Nelin LD, Jadcherla SR, Luzader P, Clark E, Fortney CA, Gutentag J, Park C, Shadd JC, Stein M, Grothause JL, Baugher H, Yosseff-Salameh L, McCool J, Das A, Gantz MG, Bann CM, Wallace D, Crawford M, Gabrio J, Leblond D, O'Donnell Auman J, Huitema CMP, Zaterka-Baxter KM, Van Meurs KP, Chock VY, Stevenson DK, Ball MB, Proud MS, Reichert EN, Williams RJ, Collins MV, Cosby SS, McNair T, Estes M, Hagood K, Devaskar U, Garg M, Chanlaw T, Geller R, Bell EF, Colaizy TT, Baack ML, Ellsbury DL, Brumbaugh JE, Johnson KJ, Henning MM, Elenkiwich C, Goeke CA, Broadbent M, Hogden LA, Klein JM, Dagle JM, Schmelzel ML, Walker JR, Bass DB, Tud TL, Watterberg KL, Fuller J, Ohls RK, Lacy CB, Beauman SS, Hartenberger C, Hanson M, Kuan E, Eichenwald EC, Schmidt B, Kirpalani H, DeMauro SB, Abbasi S, Catts C, Chaudhary AS, Ghavam S, Mancini T, Snyder J, D'Angio CT, Guillet R, Reynolds AM, Lakshminrusimha S, Kent A, Binion K, Bowman M, Donato J, Guilford S, Hunn J, Jensen RL, Li E, Maffett D, Orme C, Prinzing D, Reubens L, Rochez D, Rowan M, Sabaratnam P, Sacilowski M, Scorsone AM, Wadkins HIM, Williams A, Wynn K, Jones R, Wyckoff M, Sánchez PJ, Brion LP, Vasil DM, Chen L, DeLeon MM, Eubanks F, Pavageau L, Sepulveda P, Yoder BA, Baserga M, Minton SD, Sheffield MJ, Rau CA, Burnett J, Davis B, Christensen S, Loertscher MC, Marchant T, Maxson E, McGrath K, Elmont JO, Parry M, Schaefer ST, Weaver-Lewis K, Woodbury KD, Shankaran S, Natarajan G, Chawla S, Sood BG, Childs K, Panaitescu B, Bara R, Barks J, Christensen MK, Wiggins SA, White DF. "Duration of noninvasive respiratory support and risk for bronchopulmonary dysplasia or death." Journal of perinatology : official journal of the California Perinatal Association.. 2022 Jan 15; Epub 2022 Jan 15.

Books & Chapters

Chapter Title: Biostatistics in Research
Book Title: Avery's Neonatology Review
Author List: D'Angio CT.
Edited By: Chess PR.
Published By: Elsevier 2019 in New York

Chapter Title: Epidemiology and Clinical Research Design
Book Title: Avery's Neonatology Review
Author List: D'Angio CT.
Edited By: Chess PR.
Published By: Elsevier 2019 in New York

Chapter Title: Applying Research to Clinical Practice
Book Title: Avery's Neonatology Review
Author List: D'Angio CT.
Edited By: Chess PR.
Published By: Elsevier 2019 in New York