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Carl T. D'Angio, M.D.

Contact Information

Phone Numbers

Office: (585) 275-2972

Fax: (585) 461-3614

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

assignmentAccepting New Patients

Faculty Appointments

Patient Care Setting



Dr. D'Angio is Chief of the Division of Neonatology. He is an attending neonatologist at both URMC and Rochester General Hospital. In collaboration with other members of the neonatal team, he strives to provide compassionate, cutting-edge medical care to at-risk or critically ill newborns. Dr. D'Angio's particular clinical interests are infection and immunity in the newborn and the prevention of lung injury.

Professional Background

Dr. D’Angio attended medical school at Johns Hopkins University and received his Pediatric training at the Children’s Hospital of Philadelphia before arriving in Rochester in 1991 to complete a Fellowship in Neonatal-Perinatal Medicine. He has been a member of the University of Rochester faculty since 1994.


Dr. D'Angio's research focuses on clinical trials of therapies in the newborn. He is principal investigator for a combined University of Rochester-University of Buffalo site in the NICHD Neonatal Research Network, a 15-center consortium performing research in newborns. He has particular interest in immunizations and infections in the premature infant, lung injury, prevention of catheter-related infections, neonatal outcomes and clinical and research ethics.



MD | Johns Hopkins University School of Medicine (USA)

Post-doctoral Training & Residency

07/01/1991 - 06/30/1994
Fellowship in Neonatology at University of Rochester Medical Center

07/01/1985 - 06/30/1987
Residency in Pediatrics at Children's Hospital of Philadelphia

07/01/1984 - 06/30/1985
Internship in Pediatrics at Children's Hospital of Philadelphia

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2011 - 2012
America's Top Doctors

2009 - 2010
Who's Who in Medicine and Healthcare

America's Top Doctors

2008 - 2009
Who's Who in America

2007 - 2010
Guide to America's Top Pediatricians

2004 - 2010
Best Doctors in America

1999 - 2000
Buswell Fellowship Award, University of Rochester

Bicentennial Unit Commendation, US Public Health Service

The PHS Citation, US Public Health Service

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Clinical Trials

Management of the Patent Ductus Arteriosus in Premature Infants Trial (PDA Trial)

Lead Researcher: Carl T D'angio

Patent ductus arteriosus (PDA) is an extra blood vessel found in babies before birth and just after birth. In most babies who have an otherwise normal heart, the PDA will shrink and close on its own in the first few days of life. If it stays open longer, it may cause extra blood to flow to the lungs. This study estimates the risks and benefits of active treatment versus expectant management of premature babies with patent ductus arteriosus.

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A Randomized Controlled Trial of the Effect Of Hydrocortisone on Survival Without Bronchopulmonary Dysplasia and on Neurodevelopmental Outcomes at 22 - 26 Months of Age in Intubated Infants < 30 Weeks Gestation Age

Lead Researcher: Carl T D'angio

The Hydrocortisone and Extubation study will test if giving hydrocortisone for 10 days improves survival for premature infants who have a breathing tube. Infants will either receive hydrocortisone or placebo.

View Study Details


Journal Articles

Ackley D, Wang H, D'Angio CT, Meyers J, Young BE. "Human milk-derived fortifiers are linked with feed extension due to Hypoglycemia in infants <1250?g or <30 weeks: a matched retrospective chart review." Journal of perinatology : official journal of the California Perinatal Association.. 2023 Mar 29; Epub 2023 Mar 29.

Chock VY, Smith E, Tan S, Ball MB, Das A, Hintz SR, Kirpalani H, Bell EF, Chalak LF, Carlo WA, Cotten CM, Widness JA, Kennedy KA, Ohls RK, Seabrook RB, Patel RM, Laptook AR, Mancini T, Sokol GM, Walsh MC, Yoder BA, Poindexter BB, Chawla S, D'Angio CT, Higgins RD, Van Meurs KP, . "Early brain and abdominal oxygenation in extremely low birth weight infants." Pediatric research.. 2022 May 5; Epub 2022 May 05.

Bell EF, Hintz SR, Hansen NI, Bann CM, Wyckoff MH, DeMauro SB, Walsh MC, Vohr BR, Stoll BJ, Carlo WA, Van Meurs KP, Rysavy MA, Patel RM, Merhar SL, Sánchez PJ, Laptook AR, Hibbs AM, Cotten CM, D'Angio CT, Winter S, Fuller J, Das A, . "Mortality, In-Hospital Morbidity, Care Practices, and 2-Year Outcomes for Extremely Preterm Infants in the US, 2013-2018." JAMA.. 2022 Jan 18; 327(3):248-263.

Books & Chapters

Chapter Title: Biostatistics in Research
Book Title: Avery's Neonatology Review
Author List: D'Angio CT.
Edited By: Chess PR.
Published By: Elsevier 2019 in New York

Chapter Title: Epidemiology and Clinical Research Design
Book Title: Avery's Neonatology Review
Author List: D'Angio CT.
Edited By: Chess PR.
Published By: Elsevier 2019 in New York

Chapter Title: Applying Research to Clinical Practice
Book Title: Avery's Neonatology Review
Author List: D'Angio CT.
Edited By: Chess PR.
Published By: Elsevier 2019 in New York