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Edward G. Freedman, Ph.D.

Contact Information

Phone Numbers

Office: (585) 273-1892

Biography

Research

Effects of mild traumatic brain injury (sports-related concussion) on eye-head-hand coordination. Sports-related concussions (mild traumatic brain injuries or mTBI) are estimated to occur between 1.6 and 3.8 million times annually in the United States. The dangers of repeated injuries can be severe, particularly if additional impacts occur before full recovery. Prevention, identification, treatment, rehabilitation, and determination of recovery time-points are largely inadequate due to the paucity of parametric factors that can be easily and reliably measured both in the field and in the clinic. The overarching goal of the proposed study is to identify behavioral markers of mTBI that will ultimately help protect athletes from the dangers of premature return to full activity by tracking and facilitating recovery after injury. To accomplish this, a battery of visual-spatial tasks has been designed that require coordination of the eyes, head and hand and address sensorimotor plasticity, spatial working memory, and visuo-spatial orientation. These particular tasks have been selected because they permit a focused assessment of a variety of critical brain functions. Functions that when disrupted by mTBI can result in disorientation, dysmetria, and dyscoordination and are often symptoms of mild TBI in human subjects as well as in animal models of TBI. Careful analysis of movement kinematics and coordination during eye-head-hand orienting movements, movements to remembered target locations, visual guidance and control of hand trajectories, and tasks that require adaptive plasticity of coordination will yield parameters that pinpoint effects of mTBI, its progression and recovery to an extent that existing clinical exams and tests do not allow. For more information visit the Lab Website: http://www.urmc.rochester.edu/labs/freedman-lab/

Credentials

Faculty Appointments

Education

1986
BS | Brown University
Biology

1996
PhD | Univ of Pennsylvania
Neuroscience

1992
MS | Cornell University
Neurobiology

Awards

2002
NSF CAREER Award

2001
Alfred P. Sloan Research Fellow.

1997
Donald B. Lindsley Prize in Behavioral Neuroscience, (The Grass Foundation/The Society for Neuroscience).

1997
Saul Winegrad, M.D. Award for outstanding dissertation (Neuroscience) - Biomedical Graduate Studies,
Location: Univ. of Pennsylvania.

1996
Louis B. Flexner Award for outstanding dissertation research - Institute of Neurological Sciences,
Location: Univ. of Pennsylvania

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Publications

Journal Articles

1/2014
Walton MM, Freedman EG. "Activity of long-lead burst neurons in pontine reticular formation during head-unrestrained gaze shifts." Journal of neurophysiology.. 2014 Jan 0; 111(2):300-12. Epub 2013 Oct 30.

10/2011
Walton MM, Freedman EG. "Gaze shift duration, independent of amplitude, influences the number of spikes in the burst for medium-lead burst neurons in pontine reticular formation." Experimental brain research.. 2011 Oct 0; 214(2):225-39. Epub 2011 Aug 14.

7/2011
Shah P, Freedman EG. "Bar and line graph comprehension: an interaction of top-down and bottom-up processes." Topics in cognitive science.. 2011 Jul 0; 3(3):560-78. Epub 2009 Dec 11.

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