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Paul G. Rothberg, Ph.D.


Contact Information

Phone Numbers

Appointment: (585) 350-2600

Office: (585) 273-2229

Fax: (585) 273-5120

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

assignmentAccepting New Patients


Dr. Rothberg is Director of the Molecular Diagnostics Section of the Strong Health clinical laboratories. The Molecular Diagnostics Section uses the techniques of molecular biology to aid in the diagnosis of human disease. Dr. Rothberg is responsible for the planning and development of laboratory tests that support the care of patients with inherited disease, cancer and infectious disease. His research interests include the development of new testing strategies for the measurement of minimal residual disease in cancer patients, and the development of methods to predict response to therapy.


Dr. Rothberg's research focuses on deciphering the role of human genetic variation in the development of disease. Particular areas of focus include cancer and neurodegeneration. Current areas of investigation include studies on the molecular genetics of neuronal ceroid lipofuscinosis (Batten disease) in collaboration with the Batten Disease Clinical and Research Center, the early prediction of drug resistance in chronic myeloid leukemia, and the role of germline variation in the prognosis of prostate cancer.


Faculty Appointments


  • Clinical Molecular Genetics - American Board of Pathology


BA | Cuny Queens College

PhD | St Univ at Stony Brook
Molecular Biology

Post-doctoral Training & Residency

03/01/1982 - 08/31/1985
Fellowship in at Fox Chase Cancer Center


Journal Articles

Helber MJ, Moore JE, Williams AM, Meacham PJ, Rothberg PG, Zent CS. "Ibrutinib therapy for lymphoplasmacytic lymphoma." American journal of hematology.. 2017 Sep 0; 92(9):E542-E544. Epub 2017 Jun 09.

Bax MJ, Brown MD, Rothberg PG, Laughlin TS, Scott GA. "Pigmented epithelioid melanocytoma (animal-type melanoma): An institutional experience." Journal of the American Academy of Dermatology.. 2017 Aug 0; 77(2):328-332. Epub 2017 Apr 14.

Wang X, El-Halaby AA, Zhang H, Yang Q, Laughlin TS, Rothberg PG, Skinner K, Hicks DG. "P53 alteration in morphologically normal/benign breast luminal cells in BRCA carriers with or without history of breast cancer." Human pathology.. 2017 Apr 21; Epub 2017 Apr 21.

Books & Chapters

Chapter Title: Use of DNA plymorphisms to monitor engraftment after allogeneic bone marrow transplantation
Book Title: Clinics in Laboratory Medicine 17
Author List: Rothberg, P.G., Gamis, A.S., Baker, D.
Published By: W. B. Saunders1997

Chapter Title: Adventures in MYC-ology
Book Title: Advances in Genome Biology
Author List: Rothberg, P.G.; Heruth, D.P.
Edited By: Ram S. Verma
Published By: JAI Press Inc1995

Chapter Title: Amplification and activation of the c-myc oncogene in adenocarcinoma of the large bowel.
Book Title: Familial Adenomatous Polyposis
Author List: Herold, K.M.; Rothberg, P.G
Published By: Alan R. Liss, Inc1989