Catherine E. Ovitt, Ph.D.

Catherine E. Ovitt, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 611
Rochester, NY 14642

Office: (585) 275-2920
Fax: (585) 276-0190
Lab: (585) 273-3076

Research Bio

Normal function of the salivary glands is critical for the maintenance of oral health. Radiation treatment of patients with head and neck cancers, as well as autoimmune diseases such as Sjögren's syndrome cause cellular damage in the salivary glands that is usually severe, irreversible, and impairs normal function. The long-range goal of this laboratory is to establish therapeutic strategies for repair or regeneration of the salivary glands. Basic research projects in our laboratory include the identification and characterization of progenitor cells involved in salivary gland development and regeneration, and the factors required for differentiation of secretory cells. Applied projects address strategies for protection of the salivary glands from radiation-induced damage, and for promoting regeneration of damaged glands.

Recent Journal Articles

Showing the 5 most recent journal articles. 31 available »

2016 Dec 27
Shubin AD, Felong TJ, Schutrum BE, Joe DS, Ovitt CE, Benoit DS. "Encapsulation of primary salivary gland cells in enzymatically degradable poly(ethylene glycol) hydrogels promotes acinar cell characteristics." Acta biomaterialia. 2016 Dec 27; Epub 2016 Dec 27.
Weng, PL; Vinjamuri, M; Ovitt, CE. "Ascl3 transcription factor marks a distinct progenitor lineage for non-neuronal support cells in the olfactory epithelium." Scientific Reports. 2016; 6: 38199. Link
Maruyama EO, Aure MH, Xie X, Myal Y, Gan L, Ovitt CE. "Cell-Specific Cre Strains For Genetic Manipulation in Salivary Glands." PloS one. 2016 11(1):e0146711. Epub 2016 Jan 11.
2015 Nov
Aure MH, Arany S, Ovitt CE. "Salivary Glands: Stem Cells, Self-duplication, or Both?" Journal of dental research. 2015 Nov; 94(11):1502-7. Epub 2015 Aug 18.
2015 Jun
Shubin AD, Felong T, Graunke D, Ovitt CE, Benoit D. "Development of poly(ethylene glycol) hydrogels for salivary gland tissue engineering applications." Tissue engineering. Part A. 2015 Jun; 21(11-12):1733-51. Epub 2015 Apr 17.

Current Appointments

Associate Professor - Department of Biomedical Genetics, Center for Oral Biology (SMD) - Primary


PhD | Molecular Biology | Washington University1987
BS | Arts & Sciences | University of Connecticut1977

Post-Doctoral Training & Residency

Postdoctoral Fellow, European Molecular Biology Laboratory, Heidelberg, Germany 1997