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Catherine E. Ovitt, Ph.D.


Showing all 51 journal articles & 0 books available

Journal Articles

Mereness JA, Piraino L, Chen CY, Moyston T, Song Y, Shubin A, DeLouise LA, Ovitt CE, Benoit DSW. "Slow hydrogel matrix degradation enhances salivary gland mimetic phenotype." Acta biomaterialia.. 2023 May 5; Epub 2023 May 05.

Uchida H, Ingalls MH, Maruyama EO, Johnston CJ, Hernady E, Faustoferri RC, Ovitt CE. "Short-term and bystander effects of radiation on murine submandibular glands." Disease models & mechanisms.. 2022 Oct 20; Epub 2022 Oct 20.

Song Y, Uchida H, Sharipol A, Piraino L, Mereness JA, Ingalls MH, Rebhahn J, Newlands SD, DeLouise LA, Ovitt CE, Benoit DSW. "Author Correction: Development of a functional salivary gland tissue chip with potential for high-content drug screening." Communications biology.. 2022 Mar 30; 5(1):315. Epub 2022 Mar 30.

Song Y, Sharipol A, Uchida H, Ingalls MH, Piraino L, Mereness JA, Moyston T, DeLouise LA, Ovitt CE, Benoit DSW. "Encapsulation of Primary Salivary Gland Acinar Cell Clusters and Intercalated Ducts (AIDUCs) within Matrix Metalloproteinase (MMP)-Degradable Hydrogels to Maintain Tissue Structure and Function." Advanced healthcare materials.. 2022 Jan 6; :e2101948. Epub 2022 Jan 06.

Uchida H, Ovitt CE. "Novel impacts of saliva with regard to oral health." The Journal of prosthetic dentistry.. 2021 Jun 14; Epub 2021 Jun 14.

Song Y, Uchida H, Sharipol A, Piraino L, Mereness JA, Ingalls MH, Rebhahn J, Newlands SD, DeLouise LA, Ovitt CE, Benoit DSW. "Author Correction: Development of a functional salivary gland tissue chip with potential for high-content drug screening." Communications biology.. 2021 Apr 30; 4(1):533. Epub 2021 Apr 30.

Song Y, Uchida H, Sharipol A, Piraino L, Mereness JA, Ingalls MH, Rebhahn J, Newlands SD, DeLouise LA, Ovitt CE, Benoit DSW. "Development of a functional salivary gland tissue chip with potential for high-content drug screening." Communications biology.. 2021 Mar 19; 4(1):361. Epub 2021 Mar 19.

Luitje ME, Israel AK, Cummings MA, Giampoli EJ, Allen PD, Newlands SD, Ovitt CE. "Long-term maintenance of acinar cells in human submandibular glands after radiation therapy." International journal of radiation oncology, biology, physics.. 2020 Nov 9; Epub 2020 Nov 09.

Shubin AD, Sharipol A, Felong TJ, Weng PL, Schutrum BE, Joe DS, Aure MH, Benoit DSW, Ovitt CE. "Stress or injury induces cellular plasticity in salivary gland acinar cells." Cell and tissue research.. 2020 Jan 4; Epub 2020 Jan 04.

Weng PL, Luitje ME, Ovitt CE. "Cellular Plasticity in Salivary Gland Regeneration." Oral diseases.. 2019 Sep 27; Epub 2019 Sep 27.

Ingalls MH, Hollomon AJ, Newlands SD, McDavid AN, Ovitt CE. "Intrinsic mitotic activity supports the human salivary gland acinar cell population." FEBS letters.. 2019 Sep 20; Epub 2019 Sep 20.

Weng PL, Aure MH, Ovitt CE. "Concise Review: A critical evaluation of criteria used to define salivary gland stem cells." Stem cells.. 2019 Jun 7; Epub 2019 Jun 07.

Varghese JJ, Hansen ME, Sharipol A, Ingalls MH, Ormanoski MA, Newlands SD, Ovitt CE, Benoit DSW. "Salivary gland cell aggregates are derived from self-organization of acinar lineage cells." Archives of oral biology.. 2019 Jan; 97:122-130. Epub 2018 Oct 22.

Varghese JJ, Schmale IL, Mickelson D, Hansen ME, Newlands SD, Benoit DSW, Korshunov VA, Ovitt CE. "Localized Delivery of Amifostine Enhances Salivary Gland Radioprotection." Journal of dental research.. 2018 Oct; 97(11):1252-1259. Epub 2018 Apr 10.

Weng PL, Aure MH, Maruyama T, Ovitt CE. "Limited Regeneration of Adult Salivary Glands after Severe Injury Involves Cellular Plasticity." Cell reports.. 2018 Aug 7; 24(6):1464-1470.e3.

Varghese JJ, Schmale IL, Hansen ME, Newlands SD, Benoit DSW, Ovitt CE. "Murine Salivary Functional Assessment via Pilocarpine Stimulation Following Fractionated Radiation." Journal of visualized experiments : JoVE.. 2018 May 4; (135)Epub 2018 May 04.

Varghese JJ, Schmale IL, Wang Y, Hansen ME, Newlands SD, Ovitt CE, Benoit DSW. "Retroductal Nanoparticle Injection to the Murine Submandibular Gland." Journal of visualized experiments : JoVE.. 2018 May 3; (135)Epub 2018 May 03.

Gao X, Oei MS, Ovitt CE, Sincan M, Melvin JE. "Transcriptional profiling reveals gland-specific differential expression in the three major salivary glands of the adult mouse." Physiological genomics.. 2018 Apr 1; 50(4):263-271. Epub 2018 Jan 26.

Malcolm DW, Varghese JJ, Sorrells JE, Ovitt CE, Benoit DSW. "The Effects of Biological Fluids on Colloidal Stability and siRNA Delivery of a pH-Responsive Micellar Nanoparticle Delivery System." ACS nano.. 2018 Jan 23; 12(1):187-197. Epub 2017 Dec 15.

Shubin AD, Felong TJ, Schutrum BE, Joe DS, Ovitt CE, Benoit DS. "Encapsulation of primary salivary gland cells in enzymatically degradable poly(ethylene glycol) hydrogels promotes acinar cell characteristics." Acta biomaterialia.. 2017 Mar 1; 50:437-449. Epub 2016 Dec 27.

Weng PL, Vinjamuri M, Ovitt CE. "Ascl3 transcription factor marks a distinct progenitor lineage for non-neuronal support cells in the olfactory epithelium." Scientific reports.. 2016 Dec 2; 6:38199. Epub 2016 Dec 02.

Maruyama EO, Aure MH, Xie X, Myal Y, Gan L, Ovitt CE. "Cell-Specific Cre Strains For Genetic Manipulation in Salivary Glands." PloS one.. 2016 11(1):e0146711. Epub 2016 Jan 11.

Aure MH, Arany S, Ovitt CE. "Salivary Glands: Stem Cells, Self-duplication, or Both?" Journal of dental research.. 2015 Nov; 94(11):1502-7. Epub 2015 Aug 18.

Shubin AD, Felong T, Graunke D, Ovitt CE, Benoit D. "Development of poly(ethylene glycol) hydrogels for salivary gland tissue engineering applications." Tissue engineering. Part A.. 2015 Jun; 21(11-12):1733-51. Epub 2015 Apr 17.

Aure MH, Konieczny SF, Ovitt CE. "Salivary gland homeostasis is maintained through acinar cell self-duplication." Developmental cell.. 2015 Apr 20; 33(2):231-7. Epub 2015 Apr 02.

Arany S, Benoit DS, Dewhurst S, Ovitt CE. "Nanoparticle-mediated gene silencing confers radioprotection to salivary glands in vivo." Molecular therapy : the journal of the American Society of Gene Therapy.. 2013 Jun; 21(6):1182-94. Epub 2013 Mar 19.

Arany S, Xu Q, Hernady E, Benoit DS, Dewhurst S, Ovitt CE. "Pro-apoptotic gene knockdown mediated by nanocomplexed siRNA reduces radiation damage in primary salivary gland cultures." Journal of cellular biochemistry.. 2012 Jun; 113(6):1955-65.

Rugel-Stahl A, Elliott ME, Ovitt CE. "Ascl3 marks adult progenitor cells of the mouse salivary gland." Stem cell research.. 2012 May; 8(3):379-87. Epub 2012 Jan 31.

Arany S, Catalán MA, Roztocil E, Ovitt CE. "Ascl3 knockout and cell ablation models reveal complexity of salivary gland maintenance and regeneration." Developmental biology.. 2011 May 15; 353(2):186-93. Epub 2011 Mar 04.

Lan Y, Liu H, Ovitt CE, Jiang R. "Generation of Osr1 conditional mutant mice." Genesis : the journal of genetics and development.. 2011 May; 49(5):419-22. Epub 2011 Apr 02.

Liu W, Watson SS, Lan Y, Keene DR, Ovitt CE, Liu H, Schweitzer R, Jiang R. "The atypical homeodomain transcription factor Mohawk controls tendon morphogenesis." Molecular and cellular biology.. 2010 Oct; 30(20):4797-807. Epub 2010 Aug 09.

Gao Y, Lan Y, Ovitt CE, Jiang R. "Functional equivalence of the zinc finger transcription factors Osr1 and Osr2 in mouse development." Developmental biology.. 2009 Apr 15; 328(2):200-9. Epub 2009 Jan 14.

Bullard T, Koek L, Roztocil E, Kingsley PD, Mirels L, Ovitt CE. "Ascl3 expression marks a progenitor population of both acinar and ductal cells in mouse salivary glands." Developmental biology.. 2008 Aug 1; 320(1):72-8. Epub 2008 Apr 23.

Lan Y, Wang Q, Ovitt CE, Jiang R. "A unique mouse strain expressing Cre recombinase for tissue-specific analysis of gene function in palate and kidney development." Genesis : the journal of genetics and development.. 2007 Oct; 45(10):618-24.

Chen J, Bush JO, Ovitt CE, Lan Y, Jiang R. "The TGF-beta pseudoreceptor gene Bambi is dispensable for mouse embryonic development and postnatal survival." Genesis : the journal of genetics and development.. 2007 Aug; 45(8):482-6.

Nakamoto T, Srivastava A, Romanenko VG, Ovitt CE, Perez-Cornejo P, Arreola J, Begenisich T, Melvin JE. "Functional and molecular characterization of the fluid secretion mechanism in human parotid acinar cells." American journal of physiology. Regulatory, integrative and comparative physiology.. 2007 Jun; 292(6):R2380-90. Epub 2007 Mar 08.

Begenisich T, Nakamoto T, Ovitt CE, Nehrke K, Brugnara C, Alper SL, Melvin JE. "Physiological roles of the intermediate conductance, Ca2+-activated potassium channel Kcnn4." The Journal of biological chemistry.. 2004 Nov 12; 279(46):47681-7. Epub 2004 Sep 03.

Lan Y, Ovitt CE, Cho ES, Maltby KM, Wang Q, Jiang R. "Odd-skipped related 2 (Osr2) encodes a key intrinsic regulator of secondary palate growth and morphogenesis." Development.. 2004 Jul; 131(13):3207-16. Epub 2004 Jun 02.

Schmidt D, Ovitt CE, Anlag K, Fehsenfeld S, Gredsted L, Treier AC, Treier M. "The murine winged-helix transcription factor Foxl2 is required for granulosa cell differentiation and ovary maintenance." Development.. 2004 Feb; 131(4):933-42. Epub 2004 Jan 21.

Ronfani L, Ferraguti M, Croci L, Ovitt CE, Schöler HR, Consalez GG, Bianchi ME. "Reduced fertility and spermatogenesis defects in mice lacking chromosomal protein Hmgb2." Development.. 2001 Apr; 128(8):1265-73.

De Felice M, Ovitt C, Biffali E, Rodriguez-Mallon A, Arra C, Anastassiadis K, Macchia PE, Mattei MG, Mariano A, Schöler H, Macchia V, Di Lauro R. "A mouse model for hereditary thyroid dysgenesis and cleft palate." Nature genetics.. 1998 Aug; 19(4):395-8.

Brehm A, Ovitt CE, Schöler HR. "Oct-4: more than just a POUerful marker of the mammalian germline?" APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.. 1998 Jan; 106(1):114-24; discussion 124-6.

Bertocchini F, Ovitt CE, Conti A, Barone V, Schöler HR, Bottinelli R, Reggiani C, Sorrentino V. "Requirement for the ryanodine receptor type 3 for efficient contraction in neonatal skeletal muscles." The EMBO journal.. 1997 Dec 1; 16(23):6956-63.

Yeom YI, Fuhrmann G, Ovitt CE, Brehm A, Ohbo K, Gross M, Hübner K, Schöler HR. "Germline regulatory element of Oct-4 specific for the totipotent cycle of embryonal cells." Development.. 1996 Mar; 122(3):881-94.

Ludwig T, Munier-Lehmann H, Bauer U, Hollinshead M, Ovitt C, Lobel P, Hoflack B. "Differential sorting of lysosomal enzymes in mannose 6-phosphate receptor-deficient fibroblasts." The EMBO journal.. 1994 Aug 1; 13(15):3430-7.

Ludwig T, Ovitt CE, Bauer U, Hollinshead M, Remmler J, Lobel P, Rüther U, Hoflack B. "Targeted disruption of the mouse cation-dependent mannose 6-phosphate receptor results in partial missorting of multiple lysosomal enzymes." The EMBO journal.. 1993 Dec 15; 12(13):5225-35.

Wang ZQ, Ovitt C, Grigoriadis AE, Möhle-Steinlein U, Rüther U, Wagner EF. "Bone and haematopoietic defects in mice lacking c-fos." Nature.. 1992 360(6406):741-5.

Seetharam S, Ovitt C, Strauss AW, Rubin D, Alpers DH. "Fat feeding stimulates only one of the two mRNAs encoding rat intestinal membranous and secreted alkaline phosphatase." Biochemical and biophysical research communications.. 1987 May 29; 145(1):363-8.

Ovitt CE, Strauss AW, Alpers DH, Chou JY, Boime I. "Expression of different-sized placental alkaline phosphatase mRNAs in placenta and choriocarcinoma cells." Proceedings of the National Academy of Sciences of the United States of America.. 1986 Jun; 83(11):3781-5.

Policastro P, Ovitt CE, Hoshina M, Fukuoka H, Boothby MR, Boime I. "The beta subunit of human chorionic gonadotropin is encoded by multiple genes." The Journal of biological chemistry.. 1983 Oct 10; 258(19):11492-9.

Ordahl CP, Kioussis D, Tilghman SM, Ovitt CE, Fornwald J. "Molecular cloning of developmentally regulated, low-abundance mRNA sequences from embryonic muscle." Proceedings of the National Academy of Sciences of the United States of America.. 1980 Aug; 77(8):4519-23.