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Paul Spencer Brookes, Ph.D.

Contact Information

Phone Numbers

Appointment: (585) 276-3000

Research Labs

Please visit my lab' web-site for more details about our research

Visit Lab Website

Credentials

Faculty Appointments

Education

1993
BS | UK - Non-Medical School
Biochemistry

1997
PhD | UK-Cambridge U Med Sch
Biochemistry

Awards

2006 - 2006
Anthony Linnane Award for outstanding contribution to mitochondrial research
Sponsor: United Mitochondrial Disease Foundation

1999
Young Investigator Award
Sponsor: 6th Annual Meeting, Society for Free Radical Biology & Medicine

Publications

Journal Articles

8/10/2017
Nadtochiy SM, Wang YT, Zhang J, Nehrke K, Schafer X, Welle K, Ghaemmaghami S, Munger J, Brookes PS. "Potential mechanisms linking SIRT activity and hypoxic 2-hydroxyglutarate generation: no role for direct enzyme (de)acetylation." The Biochemical journal.. 2017 Aug 10; 474(16):2829-2839. Epub 2017 Aug 10.

7/27/2017
Resseguie EA, Brookes PS, O'Reilly MA. "SMG-1 kinase attenuates mitochondrial ROS production but not cell respiration deficits during hyperoxia." Experimental lung research.. 2017 Jul 27; :1-11. Epub 2017 Jul 27.

7/6/2017
Wang H, Huwaimel B, Verma K, Miller J, Germain TM, Kinarivala N, Pappas D, Brookes PS, Trippier PC. "Synthesis and Antineoplastic Evaluation of Mitochondrial Complex?II (Succinate Dehydrogenase) Inhibitors Derived from Atpenin?A5." ChemMedChem.. 2017 Jul 6; 12(13):1033-1044. Epub 2017 Jun 12.

Books & Chapters

2008
Chapter Title: The interaction of mitochondrial membranes with reactive oxygen and nitrogen species
Book Title: Free Radical Effects on Membranes
Author List: Brookes PS, Wojtovich AP, Burwell LS, Hoffman DL, Nadtochiy SM
Edited By: S Matalon, S Simon, D Benos
Published By: Elsevier2008 in NY

2008
Chapter Title: Aging & Cardiac Ischemia: Mitochondrial Free Radical Considerations
Book Title: Oxidative Stress in Aging: From Model Systems to Human Diseases
Author List: Brookes PS, Hoffman DL
Edited By: S Miwa, K Beckman, F Muller
Published By: Springer Verlag2008 in NY

2006
Chapter Title: Methods for measuring the regulation of respiration by nitric oxide
Book Title: Mitochondria - Methods in Cell Biology Series
Author List: Shiva, S; Brookes, PS; Darley-Usmar, VM
Edited By: Eds. L Pon and Eric Schon
Published By: Press/Elsevier2006 in San Diego

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