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Maiken Nedergaard, M.D., D.M.Sc.

Contact Information

Phone Numbers

Administrative: (585) 276-4595

Office: (585) 273-2868

Fax: (585) 276-2298

Research Labs

Faculty Appointments

Credentials

Education

1983
MD | University of Copenhagen
Medicine

1988
DMSc | University of Copenhagen
Neuroscience

Post-doctoral Training & Residency

1987 - 1988
Post-Doctoral Training; Neuroscience; Cornell University Medical School

1984 - 1987
Post-Doctoral Training; Neuropathology / Physiology University of Copenhagen

1983 - 1984
Rigshospitalet; University of Copenhagen; Neurology / Neurosurgery

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Awards

2018 - 2019
Research to Prevent Blindness Stein Innovation Award

2018
China Medical University, Shenyang, China, Honorary Professorship

2016
Jeppe Juhl Prize

2016
Tagea Brandt Prize

2016
Olav Thon Alzheimer Prize

2015
Alzheimer Prize
Sponsor: Danish Alzheimer Association

2015
Newcomb Cleveland Prize
Sponsor: AAAS

2013
1 of 10 most important science discoveries
Sponsor: Science journal

2012 - Present
Elected Member Academia Europaea
Sponsor: Academia Europaea

2011 - Present
Elected Member Royal Academy of Pharmacy of Spain
Sponsor: Royal Academy of Pharmacy of Spain

2008 - Present
Elected Member of the Royal Danish Academy of Sciences
Sponsor: Royal Danish Academy of Sciences
Location: Copenhagen, Denmark

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Patents

Patent Title: Methods for Evaluating Brain-Wide Paravascular Pathway for Waste Clearance Function and Methods for Treating Neurodegenerative Disorders Based Thereon
Patent #: 6382232
Issue Date: Aug 10, 2018
Country: Japan
Invented By: Helene Benveniste, Rashid Deane, Jeffrey J Iliff, Maiken Nedergaard

Patent Title: Methods for Evaluating Brain-Wide Paravascular Pathway for Waste Clearance Function and Methods for Treating Neurodegenerative Disorders Based Thereon
Patent #: 9,901,650
Issue Date: Feb 27, 2018
Country: United States
Invented By: Helene Benveniste, Rashid Deane, Jeffrey J Iliff, Maiken Nedergaard

Patent Title: Method of Treating and Preventing Brain Impairment using Na+-K+2Cl-Cotransporter Isoform 1 Inhibitors
Patent #: 2887806
Issue Date: Nov 13, 2019
Country: Europe
Invented By: Maiken Nedergaard, Vinita Rangroo Thrane, Alexander Stanley Thrane

Patent Title: Method of Treating and Preventing Brain Impairment using Na+-K+2Cl-Cotransporter Isoform 1 Inhibitors
Patent #: FR2887806
Issue Date: Nov 13, 2019
Country: France
Invented By: Maiken Nedergaard, Vinita Rangroo Thrane, Alexander Stanley Thrane

Patent Title: Method of Treating and Preventing Brain Impairment using Na+-K+2Cl-Cotransporter Isoform 1 Inhibitors
Patent #: DE2887806
Issue Date: Nov 13, 2019
Country: Germany
Invented By: Maiken Nedergaard, Vinita Rangroo Thrane, Alexander Stanley Thrane

Patent Title: Method of Treating and Preventing Brain Impairment using Na+-K+2Cl-Cotransporter Isoform 1 Inhibitors
Patent #: GB2887806
Issue Date: Nov 13, 2019
Country: United Kingdom
Invented By: Maiken Nedergaard, Vinita Rangroo Thrane, Alexander Stanley Thrane

Patent Title: Method of Treating and Preventing Brain Impairment using Na+-K+2Cl-Cotransporter Isoform 1 Inhibitors
Patent #: 9,616,075
Issue Date: Apr 11, 2017
Country: United States
Invented By: Maiken Nedergaard, Vinita Rangroo Thrane, Alexander Stanley Thrane

Patent Title: Adenosine as a Therapeutic Tool to Improve the Efficacy of Deep Brain Stimulation
Patent #: 2180916
Issue Date: Oct 01, 2014
Country: Europe
Invented By: Maiken Nedergaard

Patent Title: Adenosine and Its Mimetics, Modulators, Transport Inhibitors, and Receptor Agonists as a Therapeutic Tool to Replace or Improve the Efficacy of Deep Brain Stimulation
Patent #: DE2180916
Issue Date: Oct 01, 2014
Country: Germany
Invented By: Maiken Nedergaard

Patent Title: Adenosine and Its Mimetics, Modulators, Transport Inhibitors, and Receptor Agonists as a Therapeutic Tool to Replace or Improve the Efficacy of Deep Brain Stimulation
Patent #: GB2180916
Issue Date: Oct 01, 2014
Country: United Kingdom
Invented By: Maiken Nedergaard

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Publications

Journal Articles

9/4/2023
Holstein-Rønsbo S, Gan Y, Giannetto MJ, Rasmussen MK, Sigurdsson B, Beinlich FRM, Rose L, Untiet V, Hablitz LM, Kelley DH, Nedergaard M. "Publisher Correction: Glymphatic influx and clearance are accelerated by neurovascular coupling." Nature neuroscience.. 2023 Sep 4; Epub 2023 Sep 04.

9/2/2023
Ozawa K, Nagao M, Konno A, Iwai Y, Vittani M, Kusk P, Mishima T, Hirai H, Nedergaard M, Hirase H. "Astrocytic GPCR-Induced Ca Signaling Is Not Causally Related to Local Cerebral Blood Flow Changes." International journal of molecular sciences.. 2023 Sep 2; 24(17)Epub 2023 Sep 02.

9/2023
Gan Y, Holstein-Rønsbo S, Nedergaard M, Boster KAS, Thomas JH, Kelley DH. "Perivascular pumping of cerebrospinal fluid in the brain with a valve mechanism." Journal of the Royal Society, Interface. 2023 Sep; 20(206):20230288. Epub 2023 Sep 20.

Books & Chapters

2012
Chapter Title: Transcriptome Analysis of Astrocytes
Book Title: Neuroglia
Author List: Lovatt, D., Nedergaard, M.
Edited By: H. Kettenmann and B. R. Ransom
Published By: Oxford Univ. Press 2012 in New York

2009
Chapter Title: Astrocytic Ca2+ Signaling: Mechanism and implications for functional brain imaging
Book Title: Dynamic Brain Imaging
Author List: Wang, X., Takano, T., Nedergaard, M.
Edited By: F. Hyder
Published By: Humana Press 2009

2008
Chapter Title: Purinergic regulation of calcium waves
Book Title: Encyclopedia of Neuroscience
Author List: Cotrina, M., Nedergaard, M.
Published By: Springer Berlin Heidelberg 2008

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Videos

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Acupuncture's Molecular Effects Pinned Down