Maiken Nedergaard, M.D., D.M.Sc.

Maiken Nedergaard, M.D., D.M.Sc.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 645
Rochester, NY 14642

Office: (585) 273-2868
Fax: (585) 276-2298
Administrative: (585) 276-4595


The biographical information for Maiken Nedergaard, M.D., D.M.Sc. is not currently available.

Awards & Honors (Local)

Elected Member Academia Europaea | Academia Europaea 2012 - Present
Elected Member Royal Academy of Pharmacy of Spain | Royal Academy of Pharmacy of Spain 2011 - Present
Elected Member of the Royal Danish Academy of Sciences | Royal Danish Academy of Sciences | Copenhagen, Denmark 2008 - Present


Bumetanide Treatment for Hyperammonemic Encephalopathy and Seizures

United States Serial NO.: 14/415,968
Filed Date: March 15, 2013
Title: Method of Treating and Preventing Brain Impairment using Na+-K+2Cl-Cotransporter Isoform 1 Inhibitors
Invented by: Maiken Nedergaard, Alexander Stanley Thrane, Vinita Rangroo Thrane
Targeting Glymphatic Clearance of Brain Waste Product to Treat Neurological Diseases

United States Serial NO.: 14/769,396
Filed Date: February 21, 2014
Title: Methods for Evaluating Brain-Wide Paravascular Pathway for Waste Clearance Function and Methods for Treating Neurodegenerative Disorders Based Thereon
Invented by: Maiken Nedergaard, Jeffrey Iliff
Human schizophrenic glial chimeric mice (SCHIZOPHRENIA)

United States Serial NO.:
Filed Date: January 1, 1899
Title: Disease Specific Human Glial Mouse Chimeras-Schizophrenia
Invented by: Steven Goldman, Maiken Nedergaard, Martha Windrem, Paul Tesar
Disease specific human glial mouse chimeras(HUNTINGTON'S)

United States Serial NO.: 14/701,245
Filed Date: April 30, 2015
Title: Non-Human Mammal Model of Human Degenerative Disorder, Uses Thereof, and Method for Treating Human Degenerative Disorder (HUNTINGTON'S)
Invented by: Steven Goldman, Paul Tesar, Martha Windrem, Maiken Nedergaard

Recent Journal Articles

Showing the 5 most recent journal articles. 230 available »

2016 Sep 1
Wang F, Wang X, Shapiro LA, Cotrina ML, Liu W, Wang EW, Gu S, Wang W, He X, Nedergaard M, Huang JH. "NKCC1 up-regulation contributes to early post-traumatic seizures and increased post-traumatic seizure susceptibility." Brain structure & function. 2016 Sep 1; Epub 2016 Sep 01.
2016 Sep
McConnell ED, Wei HS, Reitz KM, Kang H, Takano T, Vates GE, Nedergaard M. "Cerebral microcirculatory failure after subarachnoid hemorrhage is reversed by hyaluronidase." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2016 Sep; 36(9):1537-52. Epub 2015 Oct 14.
2016 Sep
Peng W, Achariyar TM, Li B, Liao Y, Mestre H, Hitomi E, Regan S, Kasper T, Peng S, Ding F, Benveniste H, Nedergaard M, Deane R. "Suppression of glymphatic fluid transport in a mouse model of Alzheimer's disease." Neurobiology of disease. 2016 Sep; 93:215-25. Epub 2016 May 24.
2016 Aug 17
Wei HS, Kang H, Rasheed ID, Zhou S, Lou N, Gershteyn A, McConnell ED, Wang Y, Richardson KE, Palmer AF, Xu C, Wan J, Nedergaard M. "Erythrocytes Are Oxygen-Sensing Regulators of the Cerebral Microcirculation." Neuron. 2016 Aug 17; 91(4):851-62. Epub 2016 Aug 04.
2016 Aug 5
Verkhratsky A, Nedergaard M. "The homeostatic astroglia emerges from evolutionary specialization of neural cells." Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 2016 Aug 5; 371(1700)

Current Appointments

Co-Director - Department of Neurosurgery, Center for Translational Neuromedicine (SMD) - Primary Administrative
Professor (Part-Time) - Department of Neurosurgery, Center for Translational Neuromedicine (SMD) - Primary
Professor - Department of Neurology (SMD)
Professor - Department of Neuroscience (SMD)


DMSc | Neuroscience | University of Copenhagen1988
MD | Medicine | University of Copenhagen1983

Post-Doctoral Training & Residency

Post-Doctoral Training; Neuroscience; Cornell University Medical School 1988
Post-Doctoral Training; Neuropathology / Physiology University of Copenhagen 1987
Rigshospitalet; University of Copenhagen; Neurology / Neurosurgery 1984