Maiken Nedergaard, M.D., D.M.Sc.

Maiken Nedergaard, M.D., D.M.Sc.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 645
Rochester, NY 14642

Office: (585) 273-2868
Fax: (585) 276-2298
Administrative: (585) 276-4595


The biographical information for Maiken Nedergaard, M.D., D.M.Sc. is not currently available.

Awards & Honors (Local)

Elected Member Academia Europaea | Academia Europaea 2012 - Present
Elected Member Royal Academy of Pharmacy of Spain | Royal Academy of Pharmacy of Spain 2011 - Present
Elected Member of the Royal Danish Academy of Sciences | Royal Danish Academy of Sciences | Copenhagen, Denmark 2008 - Present


Bumetanide Treatment for Hyperammonemic Encephalopathy and Seizures

United States Serial NO.: 14/415,968
Filed Date: March 15, 2013
Title: Method of Treating and Preventing Brain Impairment using Na+-K+2Cl-Cotransporter Isoform 1 Inhibitors
Invented by: Maiken Nedergaard, Alexander Stanley Thrane, Vinita Rangroo Thrane
Targeting Glymphatic Clearance of Brain Waste Product to Treat Neurological Diseases

United States Serial NO.: 14/769,396
Filed Date: February 21, 2014
Title: Methods for Evaluating Brain-Wide Paravascular Pathway for Waste Clearance Function and Methods for Treating Neurodegenerative Disorders Based Thereon
Invented by: Maiken Nedergaard, Jeffrey Iliff
Disease specific human glial mouse chimeras(HUNTINGTON'S)

United States Serial NO.: 14/701,245
Filed Date: April 30, 2015
Title: Non-Human Mammal Model of Human Degenerative Disorder, Uses Thereof, and Method for Treating Human Degenerative Disorder (HUNTINGTON'S)
Invented by: Steven Goldman, Paul Tesar, Martha Windrem, Maiken Nedergaard

Recent Journal Articles

Showing the 5 most recent journal articles. 218 available »

2016 Apr
Sreetama SC, Takano T, Nedergaard M, Simon SM, Jaiswal JK. "Injured astrocytes are repaired by Synaptotagmin XI-regulated lysosome exocytosis." Cell death and differentiation. 2016 Apr; 23(4):596-607. Epub 2015 Oct 09.
2016 Jan 26
Lou N, Takano T, Pei Y, Xavier AL, Goldman SA, Nedergaard M. "Purinergic receptor P2RY12-dependent microglial closure of the injured blood-brain barrier." Proceedings of the National Academy of Sciences of the United States of America. 2016 Jan 26; 113(4):1074-9. Epub 2016 Jan 11.
2015 Oct 14
McConnell ED, Wei HS, Reitz KM, Kang H, Takano T, Vates GE, Nedergaard M. "Cerebral microcirculatory failure after subarachnoid hemorrhage is reversed by hyaluronidase." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2015 Oct 14; Epub 2015 Oct 14.
2015 Oct
Iliff JJ, Goldman SA, Nedergaard M. "Implications of the discovery of brain lymphatic pathways." The Lancet. Neurology. 2015 Oct; 14(10):977-9.
2015 Sep 1
Benveniste H, Hof PR, Nedergaard M, Bechter K. "Modern cerebrospinal fluid flow research and Heinrich Quincke's seminal 1872 article on the distribution of cinnabar in freely moving animals." The Journal of comparative neurology. 2015 Sep 1; 523(13):2017-8.

Current Appointments

Frank P. Smith Professor of Neurosurgery - Department of Neurosurgery (SMD)
Professor (Part-Time) - Department of Neurosurgery, Center for Translational Neuromedicine (SMD) - Primary
Professor - Department of Neurology (SMD)
Professor - Department of Neuroscience (SMD)


DMSc | Neuroscience | University of Copenhagen1988
MD | Medicine | University of Copenhagen1983

Post-Doctoral Training & Residency

Post-Doctoral Training; Neuroscience; Cornell University Medical School 1988
Post-Doctoral Training; Neuropathology / Physiology University of Copenhagen 1987
Rigshospitalet; University of Copenhagen; Neurology / Neurosurgery 1984