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Jinjiang Pang, B.Med., Ph.D.

Contact Information

Phone Numbers

Administrative: (585) 276-7698

Office: (585) 276-7707

Fax: (585) 276-9829

Biography

Research

Blood vessels are responsible for transportation of nutrients and oxygen throughout the whole body. Changes of oxygen level or metabolites lead to neovascularization, angiogenesis or vascular network trimming (also called vessel pruning) or regression, which are essential steps for establishing a functional and hierarchical mature vascular network to meet the needs of various organs. These processes are critical for tissue development and repair, as well as being associated with many diseases (e.g. bronchopulmonary dysplasia, pulmonary artery hypertension, ischemic cardiomyopathy, retinopathy and tumor growth). The long term goal of Pang's lab is to delineate the molecular mechanisms of these events under physiological and pathological conditions.

Credentials

Education

1993
MD | Shanxi Medical University
Clinic Medicine

2001
MS | Medical College of Lanzhou University
Smooth Muscle Physiology

2004
PhD | Physiology, Peking Union Medical College & Chinese Academy of Medical sciences (PUMC &CAMC)
Cardiovascular Physiology

Post-doctoral Training & Residency

2006 - 2008
Postdoctoral Research Associate (mentor: Bradford Berk), Center for Cardiovascular Research, University of Rochester,Rochester, NY

2004 - 2006
Postdoctoral Fellow (mentor: William Chilian), Louisiana State University Health Science Center, New Orleans, LA

Awards

2008
American Heart Association Scientist Development Grant Award
Sponsor: American Heart Association

2007 - 2007
American Heart Association Cournand and Comroe Young Investigator Award

2003 - 2003
Excellent Graduate Award, PUMC & CAMS, Beijing, China

1999 - 1999
Excellent Graduate Award, Medical College of Lanzhou University, Lanzhou,China

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Publications

Journal Articles

11/14/2018
Zhu G, Lin Y, Liu H, Jiang D, Singh S, Li X, Yu Z, Fan L, Wang S, Rhen J, Li W, Xu Y, Ge J, Pang J. "Dll4-Notch1 signaling but not VEGF-A is essential for hyperoxia induced vessel regression in retina." Biochemical and biophysical research communications.. 2018 Nov 14; Epub 2018 Nov 14.

7/11/2017
Jiang D, Zhuang J, Peng W, Lu Y, Liu H, Zhao Q, Chi C, Li X, Zhu G, Xu X, Yan C, Xu Y, Ge J, Pang J. "Phospholipase C?1 Mediates Intima Formation Through Akt-Notch1 Signaling Independent of the Phospholipase Activity." Journal of the American Heart Association.. 2017 Jul 11; 6(7)Epub 2017 Jul 11.

3/31/2017
Liao P, Wang W, Li Y, Wang R, Jin J, Pang W, Chen Y, Shen M, Wang X, Jiang D, Pang J, Liu M, Lin X, Feng XH, Wang P, Ge X. "Palmitoylated SCP1 is targeted to the plasma membrane and negatively regulates angiogenesis." eLife.. 2017 Mar 31; 6Epub 2017 Mar 31.

Books & Chapters

2004
Book Title: Clinical Endocrinology (In Chinese)
Author List: Chen J, Xu R, Pang J
Published By: Shanghai Science and Technology Press. 2004

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