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Steven R. Gill, Ph.D.

Contact Information

Phone Numbers

Office: (585) 275-1003

Fax: (585) 473-9573

Research Labs

Our research interests are centered around microbial pathogens and the impact of human microbial flora on human health and disease.

Visit Our research interests are centered around microbial pathogens and the impact of human microbial flora on human health and disease. Lab Website

Faculty Appointments

Biography

Research

Our laboratory studies bacterial pathogens and diseases associated with the human microbiome. Active research areas in our laboratory include: 1) the study of human microbiome communities in neonates and infectious disease, and 2) pathogenesis and genomics of bacterial pathogens.

HUMAN MICROBIOME COMMUNITIES
Human life is dependent on a diverse community of symbiotic microbiota that have co-evolved with their human hosts to modulate crucial aspects of normal physiology, metabolism, immunity and neurologic function. We are engaged in multiple microbiome studies in areas of neonatal development, osteoarthritis, osteomyelitis, early childhood caries, atopic dermatitis and the tumoral microbiome of oral squamous cell carcinoma.

PATHOGENESIS AND GENOMICS OF BACTERIAL PATHOGENS
Staphylococcus aureus and Clostridioides difficile are among the most successful of human pathogens, capable of causing invasive and deadly opportunistic infections. We are using in vivo, biochemical and genomic approaches to identify genetic pathways and mechanisms associated with S. aureus responses to host innate immunity and adaptation of the clonal complex 30 lineage to a persistent lifestyle in the host. In addition, we are using genomic and phylogenetic approaches to assess emergence and transmission of new S. aureus and C. difficile clinical isolates throughout hospitals, long-term care facilities and the general community in Monroe County NY.

Credentials

Education

1981
B.S. | South Dakota State University
Microbiology and Chemistry

1983
M.S. | North Dakota State University
Bacteriology

1989
Ph.D. | Kansas State University
Microbiology

Post-doctoral Training & Residency

1996 - 1997
Research Associate, Johns Hopkins University, Cell Biology

1989 - 1995
Johns Hopkins School of Medicine, Cell Biology

Awards

2009
University at Buffalo Visionary Inventor

1989 - 1992
NIH Neuroscience Postdoctoral Fellowship

1988 - 1989
Wesley Foundation Predoctoral Fellowship

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Publications

Journal Articles

4/15/2022
McDavid A, Laniewski N, Grier A, Gill AL, Kessler HA, Huyck H, Carbonell E, Holden-Wiltse J, Bandyopadhyay S, Carnahan J, Dylag AM, Topham DJ, Falsey AR, Caserta MT, Pryhuber GS, Gill SR, Scheible KM. "Aberrant newborn T cell and microbiota developmental trajectories predict respiratory compromise during infancy." iScience.. 2022 Apr 15; 25(4):104007. Epub 2022 Mar 01.

3/22/2022
Bui TI, Gill AL, Mooney RA, Gill SR. "Modulation of Gut Microbiota Metabolism in Obesity-Related Type 2 Diabetes Reduces Osteomyelitis Severity." Microbiology spectrum.. 2022 Mar 22; :e0017022. Epub 2022 Mar 22.

2022
Herman KE, Yoshida T, Hughson A, Grier A, Gill SR, Beck LA, Fowell DJ. "IL-17-Dependent Dysregulated Cutaneous Immune Homeostasis in the Absence of the Wiskott-Aldrich Syndrome Protein." Frontiers in immunology.. 2022 13:817427. Epub 2022 Feb 21.

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