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Christopher S. Anderson, Ph.D.

Contact Information

Locations

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 689
Rochester, NY 14642

Faculty Appointments

Biography

Research

Research Overview:
The Anderson Laboratory develops and investigates next generation vaccines. Traditional vaccine approaches have led to over 20 human vaccines, one of the greatest preventative medical achievements of the last century. Unfortunately, these classic approaches have been ineffective in inducing long-lasting, protective immunity against the remaining majority of human pathogens. Exciting new approaches have recently emerged in the world of vaccine research including novel delivery techniques (e.g. mRNA Lipid-nanoparticles and viral-vector) and regimens (e.g. bivalent vaccines and heterologous-prime-boost). The Anderson Laboratory incorporates novel computational modeling and state-of-the-art experimental approaches to develop and understand next generation vaccines with an aim to induce long-lasting, broadly-neutralizing, humoral immunity to viruses such as Respiratory Syncytial Virus (RSV), Influenza, Human immunodeficiency virus (HIV), and SARS-CoV-2.

Publications

Journal Articles

3/17/2021
Anderson CS, Chirkova T, Slaunwhite CG, Qiu X, Walsh EE, Anderson LJ, Mariani TJ. "CX3CR1 Engagement by Respiratory Syncytial Virus Leads to Induction of Nucleolin and Dysregulation of Cilia-related Genes." Journal of virology.. 2021 Mar 17; Epub 2021 Mar 17.

6/19/2020
Anderson CS, Sangster MY, Yang H, Mariani TJ, Chaudhury S, Topham DJ. "Implementing sequence-based antigenic distance calculation into immunological shape space model." BMC bioinformatics.. 2020 Jun 19; 21(1):256. Epub 2020 Jun 19.

4/2020
Martinez-Sobrido L, Blanco-Lobo P, Rodriguez L, Fitzgerald T, Zhang H, Nguyen P, Anderson CS, Holden-Wiltse J, Bandyopadhyay S, Nogales A, DeDiego ML, Wasik BR, Miller BL, Henry C, Wilson PC, Sangster MY, Treanor JJ, Topham DJ, Byrd-Leotis L, Steinhauer DA, Cummings RD, Luczo JM, Tompkins SM, Sakamoto K, Jones CA, Steel J, Lowen AC, Danzy S, Tao H, Fink AL, Klein SL, Wohlgemuth N, Fenstermacher KJ, El Najjar F, Pekosz A, Sauer L, Lewis MK, Shaw-Saliba K, Rothman RE, Liu ZY, Chen KF, Parrish CR, Voorhees IEH, Kawaoka Y, Neumann G, Chiba S, Fan S, Hatta M, Kong H, Zhong G, Wang G, Uccellini MB, García-Sastre A, Perez DR, Ferreri LM, Herfst S, Richard M, Fouchier R, Burke D, Pattinson D, Smith DJ, Meliopoulos V, Freiden P, Livingston B, Sharp B, Cherry S, Dib JC, Yang G, Russell CJ, Barman S, Webby RJ, Krauss S, Danner A, Woodard K, Peiris M, Perera RAPM, Chan MCW, Govorkova EA, Marathe BM, Pascua PNQ, Smith G, Li YT, Thomas PG, Schultz-Cherry S. "Characterizing Emerging Canine H3 Influenza Viruses." PLoS pathogens.. 2020 Apr; 16(4):e1008409. Epub 2020 Apr 14.

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