Working Group on Clinical Research

Thomas Wychowski, MD

Optimizing AED trials in Tumor-related Epilepsy

Garvey Conference Room: 5.5220

Jonathan Mink, MD, PhD

Incorporation of a Research Track into Residency Training

Garvey Conference Room: 5.5220

Jennifer Kwon, MD, MPH

Pompe Disease Newborn Screening: Incorporating Quality Improvement into Clinical Follow-up

Garvey Conference Room: 5.5220

Kimberly Van Orden, PhD

Volunteering as Late-Life Suicide Prevention: R01 Proposal

Garvey Conference Room: 5.5220

Charles Thornton, MD

Phase 1/2a Trial of Isis 598769 in Myotonic Dystrophy

Garvey Conference Room: 5.5220

John Langfitt, PhD

Assessment of Disruptive Behavior in Sub-Saharan African Children

Garvey Conference Room: 5.5220

Jonathan Mink, MD, PhD

Embouchure Dystonia in Brass Musicians

Garvey Conference Room: 5.5220

Spyros Papapetropoulos, MD, PhD

Rewiring Drug Development in Neurodegenerative Diseases

7:45 - 8:45 am

Physical Medicine & Rehab Room: 5.4121

Christine Annis
Robert Holloway, MD, PhD

UR NEXT Update

7:45 - 8:45 am

Physical Medicine & Rehab Room: 5.4121

Robert Dworkin, PhD

FDA Qualification of Clinical Outcome Assessments: How Arduous Will It Be to Develop QUALITE-Pain

7:45 - 8:45 am

Garvey Conference Room: 5.5220

Ruth Schneider, MD
Irene Richard, MD

The Safety and Tolerability of Buspirone for the Treatment of Anxiety in Parkinson Disease

Garvey Conference Room: 5.5220

Miriam Weber, PhD

Mechanisms of Memory Dysfunction in the Menopausal Transition

7:45 - 8:45 am

Garvey Conference Room: 5.5220

Bogachan Sahim, MD, PhD

A Role for SSRI’s in Post-Stroke Visual Recovery

Garvey Conference Room: 5.5220

John Markman, MD
Jennifer Gewandter, PhD, MPH

Simplified Pain Evaluation and Communication Tool Utilizing the Electronic Record (SPECTER): A Cluster Randomized Trial

Keck Conference Room 5.5725

Charles Venuto, PharmD

Parkinson’s Disease Progression: Learning from the Past to Predict the Future

Garvey Conference Room: 5.5220

Benjamin T. Crane, MD, PhD, FACS

A New Method for Vestibular Rehabilitation

PM&R Conference Room: 5.4121

Giovanni Schifitto, MD, MS

Vascular Aging and HIV Infection

Garvey Conference Room: 5.5220

Gretchen L. Birbeck, MD, MPH

Aggressive Antipyretics for Fever Control in Pediatric CNS Malaria

Garvey Conference Room: 5.5220

E. Ray Dorsey, MD, MBA

A National Randomized, Controlled Trial of Telemedicine for Parkinson Disease

Garvey Conference Room: 5.5220

Barney J. Stern, MD

Let the GAMES (Glyburide Advantage in Malignant Edema and Stroke) Begin!

Garvey Conference Room: 5.5220

Megan Hyland, MD, MS
Jessica Robb, MD

Telemedicine in Multiple Sclerosis

PM&R Conference Room: 5-4121

Kevin Biglan, MD, MPH
Kelly Andrzejewski, DO, PhD

REACT-PD: A Study of Virtual Research Visits in a Phase III Clinical Trial

Garvey Conference Room: 5.5220

Tetsuo Ashizawa, MD

Translational Approaches in Myotonic Dystrophy

Garvey Conference Room: 5.5220

Feng (Vankee) Lin, PhD

Neurophysiological Aspects of Vision-Based Speed of Processing Cognitive Training in Older Adults with Mild Cognitive Impairment: Preparation for an R01 Application

PM&R Conference Room: 5-4121

Yeates Conwell, MD
Kimberly Van Orden, PhD

The Senior Connection- Trials and Tribulations of Recruitment through Primary Care for a Community-Based RCT

Garvey Conference Room: 5-5220

Frank J. Sasinowski, MS, MPH, JD

FDA Evaluation and Approval of Drugs for Rare Diseases: The Importance of Subpart H

Geoffrey C. Williams , MD, PhD
Robert C. Block, MD, MPH, FACP, FNLA

Enhancing Motivation for Achieving Lipid Goals with Framingham Risk

Harris A. Gelbard, MD, PhD
Michael C. Keefer, MD
Amneris E. Luque, MD
Giovanni Schifitto, MD, MS

New Opportunities for Research and Treatment of HIV-1 Associated Neurocognitive Disorders (HAND)

J. Steven Lamberti, MD

Glycine Transport Inhibitors in Schizophrenia: The Next Big Thing?

Nicholas E. Johnson, MD

Designing a Disease Progression Study in Congenital Myotonic Dystrophy

Jonathan W. Mink, MD, PhD

Task-Specific Focal Embouchure Dystonia in Musicians

Robert H. Dworkin, PhD
Robert A. Gross, MD, PhD
Michael P. McDermott, PhD

Towards a Taxonomy of Research Mischief and Misconduct

Erika Augustine, MD

First line treatment for pediatric tic disorders – A comparative effectiveness study

Kevin Biglan, MD, MPH

STEADYPD3: A Phase 3 Trial of Isradipine in Early Parkinson Disease

Jim White, MD, PhD

Goldilox and 3 Doses of Treprostinil

Annie Killoran, MD

Feasibility of Phase III Clinical Trials in Pre-Manifest Huntington’s Disease

Nancy Bennett, MD

Comparative Effectiveness of Practice-Based Diabetes Prevention Programs

Arthur Moss, MD

MADIT-Related Device Trials

Kevin Biglan, MD, MPH

STEADY3: Overview of a Phase 3 Study of Isradipine in Early Parkinson Disease

Giovanni Schifitto, MD

Does Chronic Exposure to cART Predispose Older HIV Infected Individuals to CNS Injury?

Jeffrey Statland, MD

Instrumented Timed Functional Test in FSH Dystrophy

Karl Kieburtz, MD, MPH
Kathy Wunderle

Appropriate Physician Prescribing: Impact of Industry

Gary Myers, MD

Designing & Executing the Seychelles Main Cohort Study

Kate Young, PhD

Adapting a Cost-Effectiveness Analysis to a Moving Target

Matt Bellizzi, MD, PhD

Gray Area or a Disconnect in MS Cognitive Impairment: A Clinical Study

Yi Zhang, MD

The Feasibility of Hemodynamic Monitoring Microcirculation after Subarachnoid Hemorrhage Using Transcranial Doppler

Michael McDermott, PhD
John Langfitt, PhD

ERSET: Snatching Victory from the Jaws of Defeat

Christopher P. Gallati, MD

Safety and Efficacy of Stellate Ganglion Block in the Treatment of Acute Ischemic Stroke

Yeates Conwell, MD

The Senior Connection: An RCT of peer support to reduce risk for suicide

David Herrmann, MB BCh

Proposal for a Treatment Trial for Muscle Cramps in Charcot Marie Tooth Disease

Amy-Lee Bredlau, MD, FAAP

A phase II study of Ketamine in children

Charles Venuto, PharmD

Quantifying Huntington's Disease Progression: A Pharmacometrics Approach

Rabi Tawil, MD

Optimizing Clinical Outcome Measures in FSH Muscular Dystrophy

Eric Rubinstein, JD, MPH and Lauren Farberman, MBA

UR CTSI Research Navigator Program: a full service research help desk

Curtis Benesch, MD, MPH

City-Wide Stroke Care: Raising the Bar or Quasi-Experiment?

Ronald M. Epstein, MD

A mindful communication intervention to improve quality of care, quality of caring and well-being

Anthony Pietropaoli , MD

Sodium nitrite therapy in severe sepsis: a novel intervention targeting microvascular blood flow

James Cloyd, PharmD

Challenges in developing intravenous topiramate for neonatal seizures

Robert Holloway, MD, MPH

Conflicts of interest: the perils and promise of transparency

Robert Gross, MD, PhD

Publishing trials: the editorial perspective

Mark Mapstone, PhD

Optimizing Deep Brain Stimulation for Parkinson's Disease

Katia Noyes, PhD, MPH

Multiple lessons on multiple sclerosis: results of cost-effectiveness assessment of disease modifying therapies

Karl Kieburtz, MD, MPH

Clinical trial design in movement disorders: 20 years of change

**Whipple Auditorium (2-6424)**

John Langfitt, PhD

The Promise of PROMIS (Patient-Reported Outcomes Measurement Information System)

Heather Adams, PhD

Clinical trial of a behavioral intervention in pediatric degenerative neurologic conditions

Kevin M. Biglan, MD

A randomized controlled trial of telemedicine versus in-person care for nursing home residents with Parkinson’s disease

Susan G. Fisher, PhD

The Rochester Family Health Partnership: the road to Shangri-La?

Charles Thornton, MD

Antisense oligonucleotide drugs for neurogenetic disease

Irene Richard, MD

A multicenter randomized, double-blind, placebo-controlled trial of antidepressants in Parkinson's disease

Ira Shoulson, MD

Predictors and precursors of disability in Parkinson Disease

Michelle Burack, MD

Continuous ambulatory accelerometry for passive monitoring of motor fluctuations in Parkinson disease

David Herrmann, MBBCh

Outcome measures for Charcot-Marie-Tooth neuropathy trials

Ronnie Guillet, MD, PhD

PROPHENO: Everything I’ve learned so far…and didn’t know I had to know!

**K-207**

Ryan Evans , MD

Remote assessments in clinical trials

Anton Porsteinsson, MD

CITAD: Citalopram for the treatment of agitation in dementia—challenges of designing and executing intervention studies for behavioral disturbances in dementia

John Markham , MD

What to Do When Unintended Consequences are Painful: Lessons from Three Recent FDA Advisory Committees

Michel Berg , MD

Testing the equivalence of generic and innovator AEDs: are the FDA regulations sufficient?

David Oakes , PhD

The randomized start design in Parkinson's disease, can it really be used to infer disease modification?

John Treanor , MD

Study designs for Phase 1 studies of vaccines

Giovanni Schifitto , MD

A pilot study of creatine for treatment of fatigue in HIV infected individuals

Robert Griggs, MD

The authorship lottery

Ray Dorsey , MD and Bernard Ravina, MD

Local IRB review of a multicenter trial: local costs without local context

Karl Kieburtz, MD, MPH

NET-PD multiple outcomes, global test, what does it mean?

Steve Lamberti, MD

Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE): overview of a landmark study

David Foster, MD

The 5-year experience of a dyspareunia RCT: the Vulvar Vestibulitis Clinical Trial (VVCT)

Mark Mapstone, PhD

The Rochester Aging Study: community-based research in cognitive aging

Erika Augustine, MD and the Batten Study Team

Batten Disease Clinical Trials

Anthony Almudevar, PhD

A pathway modeling approach to gene discovery

David Shprecher, DO

A clinical and biomarker discovery initiative to identify individuals with premotor Parkinson's disease

Andrew McGarry , MD

A matter of Scale: clinical trials in SCA 6

Sep 5, 2008

Adam Kelly , MD

Expanding the role of stimulant therapy in the post-stroke period

Fred Marshall , MD and Peter Como, PhD

Huntington Disease Meets the FDA, Part II: Aliens vs. Predators

Christopher Beck, PhD

Resampling approaches to statistical inference in clinical trials

Steve Lamberti , MD

Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE): overview of a landmark study

John Langfitt , PhD

Navigating NIH Peer Review: A Case Study of an RCT of Radiosurgery vs. Lobectomy for Epilepsy

Charles Duffy, MD, PhD

Late-Life Cognitive Decline: Measures and Mechanisms

Michael McDermott, PhD

Multiple outcome variables in clinical trials: an example from a planned trial in Duchenne muscular dystrophy

Ray Dorsey, MD, MBA

Randomized, controlled trial of an omega-3 fatty acid for Huntington disease

John Markman, MD

Lumbar Stenosis Outcomes Research (LUSTOR) trials I and II: a pair of double-blind, placebo-controlled crossover trials for the treatment of neurogenic intermittent claudication

Fred Marshall, MD and Peter Como, PhD

Huntington Disease meets the FDA

Michael Schlossmacher, MD

Lysosomal enzymes and alpha-synuclein steady-state

Kevin Biglan, MD, MPH and David Oakes, PhD

Dosage selection of isradipine for the treatment of Parkinson's Disease: a two-period design

Tiffani Voss, MD

The effects of sustained physiotherapy on fall reduction in Parkinson Disease

David Shprecher, DO

A peripheral leukocyte microarray investigation of tic remission in Tourette Syndrome

Lahar Mehta, MD

Heparin: a different point of view and possible application in Multiple Sclerosis

Brandy Fureman, PhD
NINDS Clinical Trial Group

NINDS Resources for Clinical Investigations

TBA

Anthony Almudevar, PhD and Roger Kurlan, MD

Some Issues in Adaptive Methodology

Giovanni Schifitto, MD

Valproic Acid for HIV-Associated Cognitive Impairment: An Enhanced Phase II Study

Roger Kurlan, MD

Identifying the best study design for pilot efficacy trials in Tourette’s Syndrome

Steven Frucht, MD
Associate Professor of Clinical Neurology
Columbia University Medical Center

Alcohol-responsive Movement Disorders - New Treatment Options

Bernard Ravina, MD, MSCE

Timing of Treatment Initiation in PD

Dan Skovronsky, MD, PhD
CEO, Avid Radiopharmaceuticals

Radiopharmaceuticals for Neurodegenerative Condition

Alec B. O'Connor, MD

Desipramine vs. Pregabalin in Older Patients with Painful Diabetic Peripheral Neuropathy or Postherpetic Neuralgia

Ronnie Guillet, MD

Treatment of Infants After Resolution of Neonatal Seizures

Robert Dworkin, MD and Steve Schwid, MD

Proof-of-Concept Trial of Omega-3 and -6 Fatty Acid Supplementation in Multiple Sclerosis (or Clinically Isolated Syndromes?)

Peter Como, PhD

Quantitative Assessment of Caregiver Burden in PD

R. Michael Poole, MD, FACP

Practice Issues in the Implementation of Adaptive Clinical Trial Designs

Jeffrey L. Cummings, MD

Disease Modifying Therapies: How will we know if they are working?

John Markham, MD

Attenuation of Chronic Pain Following Lumbar Fusion:  Proposal for a Perioperative Analgesic Trial

Kevin Biglan, MD, MPH

Study in Presymptomatic Huntington’s Disease of Coenzyme Q10 Leading to Preventive Trials

Acute Stroke Treatment: Easy as APC

Katia Noyes, PhD, MPH

Use of administrative data for examining patterns and costs of medical care: Application for Parkinson’s disease

Mark Mapstone, PhD

Practical Considerations for Cognitive Endpoints in Clinical Trials

Anthony Lang, MD

GDNF for Parkinson’s Disease: The Theory and the Evidence

Donna Palumbo, PhD

Clonidine in ADHD Treatment study (CAT) primary results

Richard A. Lewis, MD and Michael E. Shy, MD
Dept of Neurology, Wayne State University

High Dose Vitamin C Treatment of Charcot Marie Tooth Disease Type 1A

Giovanni Schifitto, MD

Identifying Relevant Biomarkers of Oxidative Stress in Subjects with HIV-Associated Cognitive Impairment

Kimberly P. Cockerham, MD
University of California, San Francisco

Thyroid Eye Disease Pilot Study and Beyond NORDIC TED 2005

William J. Groh, MD, MPH

Cardiac Involvement in Myotonic Dystrophy Type 1

Stanley Fahn, MD
Columbia University Medical Center

Study Designs For Neuroprotective Trials in PD

Aileen Shinaman, JD

COHORT: Initial Steps in Planning a Longitudinal, Observational Study of Members of the HD Community

 

Thomas Pearson, MD, MPH, PhD

Aggressive Lipid Management: Why, What, When, and in Whom?

Robert Dworkin, PhD and Michael McDermott, PhD

Combination Antineuralgic Treatment in Peripheral Neuropathic Pain

Rabi Tawil, MD and Michael McDermott, PhD

Investigation of Corticosteroid Regimens for Treatment of Duchenne Muscular Dystrophy

Jonathan W. Mink, MD, PhD

Quantitative Assessment of Chorea and Dystonia

Kathy Hoeger, MD

Clinical Trials in the Long-term Management of Polycystic Ovary Syndrome (PCOS)