Tanzy Love, PhD

Associate Professor of Biostatistics
Ph.D. (2005) Iowa State University

URMC profile

Contact Information:

University of Rochester
Dept of Biostatistics and Computational Biology
265 Crittenden Boulevard, CU 420630 
Rochester, New York 14642-0630
Office: Saunders Research Building 4144
Phone: (585) 276-5559
Fax: (585) 273-1031
E-mail: Tanzy_Love@urmc.rochester.edu

Research Interests

  • Environmental health statistics
  • Clustering and latent variable models
  • Mixed membership models and model choice
  • Normalization and preprocessing issues relating to gene expression
  • Bayesian models for QTLs and growth curves
  • Hierarchical Bayesian models for gene expression data
  • Scalable parallel model-based clustering
  • Proteomics: preprocessing and analysis

Selected Publications

  • Finding Vulnerable Subpopulations in the Seychelles Child Development Study: Effect Modification with Latent Groups, to appear in Statistical Methods in Medical Research. Love, T.M., Thurston, S.W., and Davidson, P.W.
  • Outlier Identification in Model-Based Cluster Analysis, to appear in Journal of Classification. Evans, K., Love, T.M.T., and Thurston, S.W.
  • Associations between prenatal and recent postnatal methylmercury exposure and auditory function at 19 years in the Seychelles Child Development Study. Neurotoxicology and Tetrology, 46:68-76, Nov-Dec 2014. Orlando, M.S., Dziorny, A.C., Harrington, D., Love, T.M., Shamlaye, C.S., Watson, G., van Wijngaarden, E., Davidson, P.W., and Myers, G.J.
  • Sustained Reduction of Central Line Associated Bloodstream Infections Outside the ICU through a Multihospital Collaborative Focusing on Central Line Maintenance. American Journal of Infection Control, 42(7): 723-730. 2014. Dumyati, G.; Concannon, C.; van Wijngaarden, E.; Love, T.M.T.; Graman, P.; Pettis, A.M.; Greene, L.; El-Daher, N.; Farnsworth, D.; Karr, G.; Ward, L., Knab, R.; Shelly, M. PMID: 24856587
  • General Bayesian Models for Multiple Outcomes Nested in Domains. Journal of the American Statistical Association 109(505):1-10, Jan 2014. Xiao, L., Thurston, S.W., Ruppert, D., Love, T.M. PMCID: PMC3979566
  • Autism Spectrum Disorder Phenotypes and Prenatal Exposure to Methylmercury: Results from the Seychelles Child Development Study. Epidemiology 24(5): 651–659, September 2013. van Wijngaarden, E., Davidson, P.W., Smith, T.H., Evans, K., Yost, K., Hyman, S., Love, T.M., Thurston, S.W., Watson, G.E., Zareba, G., Burns, C.M., Shamlaye, C.S., and Myers, G.J.  PMCID: PMC3732522
  • Latent Factor Regression Models for Grouped Outcomes. Biometrics, 69 (3):785-94, Sep 2013.  Woodard, D., Love, T.M., Thurston, S.W., Ruppert, D., Sathyanarayana, S., and Swan, S.H. PMID: 23845121
  • Neurodevelopmental Outcomes at 5 Years in Children Exposed Prenatally to Maternal Dental Amalgam: The Seychelles Child Development Nutrition Study. Neurotoxicology and Tetrology 39:57-62, Sep-Oct 2013. Watson, G.E., van Wijngaarden, E., Love, T.M., McSorley, E.M., Bonham, M.P., Mulhern, Yeates, A.J., Davidson, P.W., Shamlaye, C.F., Strain, J.J., Thurston, S.W., Harrington, D., Zareba, G., Wallace, J.M.W., and Myers, G.J. PMID: 23856391
  • Prenatal Exposure to Dental Amalgam in the Seychelles Child Development Nutrition Study: Associations with Neurodevelopmental Outcomes at 9 and 30 Months. Neurotoxicology, 33(6):1511--7, Dec 2012. Watson, G.E., Evans, K., Thurston, S.W., van Wijngaarden, E., Wallace, J.M.W., McSorley, E.M., Bonham, M.P., Mulhern, M.S., McAfee, A.J., Davidson, P.W., Shamlaye, C.F., Strain, J.J., Love, T.M., Zareba, G., and Myers, G.J. PMCID: PMC3576043
  • Secondhand Smoke Exposure and Serum Cytokine Levels in Healthy Children. Cytokine. 60(1):34-7, Oct 2012.Wilson, K., Westgate, S., Pier, J., Weis, E., Love, T.M., Evans, K., and Chhibber, A. PMCID: PMC3781216
  • Designing a genome-based HIV incidence assay with high sensitivity and specificity. AIDS (London, England). 25(16):F13-9, 2011, Park S.Y., Love T.M., Nelson J., Thurston S.W., Perelson A.S., Lee H.Y. PMCID: PMC3319025
  • Socioeconomic position and cognitive function in the Seychelles: a life course analysis. Neuroepidemiology.36(3):162-8. Epub 2011 Apr 20, Kobrosly R.W., van Wijngaarden E., Galea S., Cory-Slechta D.A., Love T., Hong C., Shamlaye C.F., Davidson P.W. PMCID: PMC3095839
  • Re-conceptualizing the Classification of PNAS Articles, Proceedings of the National Academy of Science, 107(49):20899-20904, December 2010, Airoldi, E., Eroseva, E., Fienberg, S., Joutard, C., Love, T.M., Shringarpure, S.  PMCID: PMC3000298
  • An Empirical Method for Establishing Positional Confidence Intervals Tailored for Composite Interval Mapping of QTL, PLoS ONE, 5(2): e9039, 2010, Crossett, A., Lauter, N., and Love, T.M.  PMCID: PMC2817735
  • Mathematical Modeling of Ultradeep Sequencing Data Reveals That Acute CD8+ T-Lymphocyte Responses Exert Strong Selective Pressure in Simian Immunodeficiency Virus-Infected Macaques, but Still Fail to Clear Founder Virus Sequences, Journal of Virology, 84(11):5802-5814, March 2010, Love, T.M., Thurston, S., Keefer, M., Dewhurst, S., and Lee, H.Y. PMCID: PMC2876615
  • Repeated measurements on Distinct Scales with Censoring - A Bayesian Approach to Microarray Analysis of Maize Journal of the American Statistical Association, 104 (486): 524-540, June 2009. Love, T.M. and Carriquiry, A.L.
  • Discovery of Latent Patterns with Hierarchical Bayesian Mixed-Membership Models and the Issue of Model Choice in Data Mining Patterns, eds. P. Poncelet, F. Masseglia, and M. Teisseire, Hershey, PA: IGI Global, Chapter IX, August 2007. Airoldi, E., Fienberg, S., Joutard, C., and Love, T.M.
  • Discovery of Latent Patterns with Hierarchical Bayesian Mixed-Membership Models and the Issue of Model Choice in Proc. of the Seventh International Workshop on Multimedia Data Mining: Merging Multimedia and Data Mining Research, August 20, 2006, Philadelphia, Pennsylvania, pp. 91-100, August 2006. Airoldi, E., Fienberg, S., Joutard, C., and Love, T.M.
  • Redesigning Discrete Math as a web-based course: Lessons and Accomplishments Journal of STEM Education Innovations and Research, 7(3--4), 25--35, July--December 2006. Love, T.M., Shelley, M., and Keinert, F.
  • Gene expression patterns during somatic embryo development and germination in maize Hi II callus cultures Plant Molecular Biology, 62(1--2), 1--14, September 2006. Che, P., Love, T.M., Frame, B.R., Carriquiry, A.L., Wang, K., and Howell, S.H.
  • Growth Hormone Benefits Children with 18q Deletions American Journal of Medical Genetics, 137(1), 9--15, August 2005. Cody, J.D., Semrud-Clikeman, M., Hardies, L.J., Lancaster, J., Ghidoni, P.D., Schaub, R.L., Thompson, N.M., Wells, L., Cornell, J.E., Love, T.M., Fox, P.T., Leach, R.J., Kaye, C.I., and Hale, D.E.

Chapters and Invited Papers

  • Hierarchical Bayesian Mixed-Membership Models and Latent Pattern Discovery. Frontiers of Statistical Decision Making and Bayesian Analysis – In Honor of James O. Berger. M.E. Chen (Ed). 1st ed. Springer Verlag, August 2010, Chapter 10.3, ISBN: 978-1-4419-6943-9. Airoldi, E., Fienberg, S., Joutard, C. and Love, T.M.
  • Estimating Gene Expression Profiles Using all Available Information. The Proceedings of the Annual Conference on Applied Statistics in Agriculture, 17, 1--32, December 2005. Love, T.M. and Carriquiry, A.L.
  • Hierarchical Bayesian methods for microarray data. Handbook of Statistics: Bioinformatics, C.R. Rao, R. Chakraborty, and P.K. Sen. (Eds). North Holland, Chapter 2: 12--38, 2012.Love, T.M. and Carriquiry, A.L.