Donate Tissue Making the decision to be an organ or tissue donor can be difficult. The decision makes us have to consider our own mortality. At the time of your death, your family will be offered the option of organ donation. If you'd like to be a donor, sign a donor card and talk to your family and friends about your wishes. It's an opportunity to give someone life. You can register your intent to be an organ or tissue donor through the New York State Donor Registry. Visit the Finger Lakes Donor Recovery Network to learn more about organ and tissue donation.