CONTACT INFORMATIONCREDENTIALSPATENTSPUBLICATIONSGlynis A. Scott, M.D.Contact InformationPhone NumbersOffice: (585) 275-8811Fax: (585) 273-1346A member of the University of Rochester Medical Faculty GroupgroupAn Accountable Health PartnerassignmentNot Accepting New PatientsLocationsUniversity of Rochester Medical CenterSchool of Medicine and Dentistry601 Elmwood Ave, Box 697Rochester, NY 14642Faculty AppointmentsProfessor - Department of Dermatology (SMD) Patient Care SettingsDermatology, PathologyBiographyResearchThere are two major projects on going in my laboratory--the first is the investigation into signaling pathways of prostaglandins in human melanocytes and melanoma, and the second is the role of Plexin receptors in melanocyte and melanoma biology. Melanocytes are pigment producing cells within the epidermis that are progenitor cells for a deadly cancer, melanoma. The production of melanin by melanocytes is a key function of melanocytes and provides photoprotection to the skin. Prostaglandins (PG) are lipid signaling molecules released by keratinocytes and melanocytes in response to ultraviolet irradiation. Our research focus is on defining signaling intermediates that mediate the effect of the two primary PG in the skin, PGE2 & PGF2?? on melanocyte dendrite extension, growth and pigment production. Our laboratory is also investigating the role of semaphorins and their receptors on melanocyte growth, differentiation, and progression to melanoma. Semaphorins are membrane bound and secreted proteins involved in neuronal pathfinding, that we have recently shown to be involved in melanocyte adhesion and dendrite formation. Our particular focus is on Semaphorin 7A and Semaphorin 4D, and their cognate receptors Plexin C1 and Plexin B1, which are lost during progression of melanocytes to melanoma. Integration of signaling intermediates with biologic functions such as proliferation, apoptosis and migration, allow us to dissect the function of PG and semaphorins in melanocyte, and to link signaling by specific receptors to downstream biologic targets important for skin pigmentation and melanoma progression.CredentialsEducation1983MD | Albany Medical College of Union UniversityPost-doctoral Training & Residency07/01/1987 - 06/30/1988Fellowship in Dermatopathology at Yale University School of Medicine07/01/1984 - 06/30/1987Residency in Pathology - Anatomic at Yale University School of Medicine07/01/1983 - 06/30/1984Internship in Internal Medicine at Albany Medical Center HospitalVIEW ALL expand_morePatentsPatent Title: Small Molecule Modulators of Melanin Expression Patent #: 9,162,984 Issue Date: Oct 20, 2015 Country: United States Invented By: Peter Gareiss, Brian R McNaughton, Benjamin Locke Miller, Glynis A ScottPublicationsJournal Articles11/2019Mitchell DC, Agnihothri R, Scott GA, Korman B, Richardson CT. "A case of concurrent systemic sclerosis and scleredema." JAAD case reports.. 2019 Nov; 5(11):940-942. Epub 2019 Oct 24. 11/2019Lerman I, Agnihothri R, Scott GA, Richardson CT. "An atypical clinical presentation of alopecia in 2 patients with systemic lupus erythematosus." JAAD case reports.. 2019 Nov; 5(11):953-956. Epub 2019 Oct 24. 8/2017Bax MJ, Brown MD, Rothberg PG, Laughlin TS, Scott GA. "Pigmented epithelioid melanocytoma (animal-type melanoma): An institutional experience." Journal of the American Academy of Dermatology.. 2017 Aug; 77(2):328-332. Epub 2017 Apr 14. VIEW ALL PUBLICATIONSClose WindowSchedule an appointment with Glynis A. Scott, M.D.Please answer the following questions to help us find the right appointment for you.Important: If you believe that you have a medical or psychiatric emergency, please call 911 or go to the nearest hospital. This website is not intended for emergency care.Have you seen this provider in the last 2 years?YesNoExisting Patient Schedule or request a follow up appointment online through MyChart. If you do not have a MyChart account, please close this window and call the appointment phone number. Glynis A. Scott, M.D. is currently scheduling for the following appointment type(s): Our policy does not permit patients to establish care with multiple providers within the same practice or specialty without prior approval. If you choose a new provider in the same office, we will cancel the appointment. Please contact the office directly with questions on this policy.