Research Meetings
March through April 2017


March 27, 2017 ( Monday )

12:00pm - 1:00pm
Department of Biology Donut Talk

Dr. Barbara Mellone, University of Connecticut

One and only: ectopic centromere formation and inactivation in Drosophila

Location:  Hutchison Hall, Lander Auditorium

Posted by:  Deborah Lawrence, Biology, 16-Jan-17 8:02am ET


March 29, 2017 ( Wednesday )

4:00pm - 5:00pm
THE Aab CVRI Seminar Series

SPEAKER: Yanni Xu, Ph.D. Visiting Associate Professor in Zheng-Gen Jin, Ph.D. lab The Aab Cardiovascular Research Institute University of Rochester Medical Center School of Medicine and Dentistry

TITLE OF TALK: "High throughput screening of new drugs for cardiovascular disease"

Location:  CVRI Conf. Room # G.11211/G.11213 MRBX/Delmonte Bldg - (Ground floor)

Posted by:  Jacqueline Velazquez, Cardiovascular Research Institute, 24-Mar-17 2:34pm ET


March 31, 2017 ( Friday )

12:00pm - 1:00pm
Pediatric Biomedical & Translational Research Seminar

Andrew Koh, MD, Assistant Professor of Pediatrics and Microbiology at the University of Texas Southwestern Medical Center and Director of Pediatric Hematopoietic Stem Cell Transplantation at the Children's Medical Center will be presenting "The Role of Gut Microbiota in the Health of Cancer and Stem Cell Transplant Patients."

Location:  Class of 62 Auditorium (G-9425)

Posted by:  Patricia Klein, Pediatrics, 20-Mar-17 4:09pm ET


3:00pm - 4:00pm
Department of Biology E2G2 Seminar

Mary Grantham, University of Rochester

TBA

Location:  Hutchison Hall, Room 316

Posted by:  Deborah Lawrence, Biology, 30-Jan-17 10:13am ET


April 3, 2017 ( Monday )

12:00pm - 1:00pm
Department of Biology Donut Talk Seminar

Dr. Benjamin Glick, University of Chicago

"Surfing the secretory pathway"

Location:  Hutchison Hall, Lander Auditorium

Posted by:  Deborah Lawrence, Biology, 27-Jan-17 1:28pm ET


12:00pm - 1:00pm
Microbiology and Immunology Department Seminar

Nicole Pecora, M.D., Ph.D Assistant Professor, University of Rochester

"Microbial Whole Genome Sequencing in the Clinical Laboratory: Implementation and Applications"

Monday, April 10, 2017 12:00-1:00 PM Upper Auditorium (Room 3-7619)

Hosted by Steve Gill, Ph.D

Co-Sponsored by XXXXX

As microbial whole genome sequencing (WGS) has become more affordable and more accessible it has begun to enter the realm of routine clinical microbiology. Promising applications include outbreak epidemiology and clonality assessment, analysis of resistance and virulence factors, studies of novel organisms, microbiome assessment, and pathogen identification in primary specimens. In particular, WGS analysis of antibiotic resistance has the unique ability to place elements in a genetic context, i.e. chromosome versus plasmid, providing information about transmissibility. In a 3 year pilot study, we assessed the utility of WGS to assess the clonality and resistance genotype of all carbapenem-resistant Enterobacteriaceae (CRE) in a Boston area hospital. Combining the genomic data with clinical metadata allowed for a rich picture of institutional antibiotic resistance, including the mobilization apparatus (transposons and plasmids) associated with different genes. Following the pilot study, prospective use of microbial WGS has provided support in numerous clinical situations, including the characterization of a series of NDM-bearing organisms, a rare but increasing component of the CRE landscape in the United States. In summary, while challenges remain to develop customized analytical pipelines as well as a clinical reporting structure, WGS is poised to make a dramatic change in the clinical microbiology laboratory and the practice of infection control.

Location:  Upper Auditorium 3-7619

Posted by:  Jack McMahon, Micro & Immunolgy, 16-Mar-17 10:22am ET


12:00pm - 1:00pm
Microbiology and Immunology Department Seminar

Nicole Pecora, M.D., Ph.D Assistant Professor, University of Rochester

"Microbial Whole Genome Sequencing in the Clinical Laboratory: Implementation and Applications"

Monday, April 10, 2017 12:00-1:00 PM Upper Auditorium (Room 3-7619)

Hosted by Steve Gill, Ph.D

As microbial whole genome sequencing (WGS) has become more affordable and more accessible it has begun to enter the realm of routine clinical microbiology. Promising applications include outbreak epidemiology and clonality assessment, analysis of resistance and virulence factors, studies of novel organisms, microbiome assessment, and pathogen identification in primary specimens. In particular, WGS analysis of antibiotic resistance has the unique ability to place elements in a genetic context, i.e. chromosome versus plasmid, providing information about transmissibility. In a 3 year pilot study, we assessed the utility of WGS to assess the clonality and resistance genotype of all carbapenem-resistant Enterobacteriaceae (CRE) in a Boston area hospital. Combining the genomic data with clinical metadata allowed for a rich picture of institutional antibiotic resistance, including the mobilization apparatus (transposons and plasmids) associated with different genes. Following the pilot study, prospective use of microbial WGS has provided support in numerous clinical situations, including the characterization of a series of NDM-bearing organisms, a rare but increasing component of the CRE landscape in the United States. In summary, while challenges remain to develop customized analytical pipelines as well as a clinical reporting structure, WGS is poised to make a dramatic change in the clinical microbiology laboratory and the practice of infection control.

Location:  Upper Auditorium 3-7619

Posted by:  Jack McMahon, Micro & Immunolgy, 16-Mar-17 10:23am ET


April 5, 2017 ( Wednesday )

4:00pm - 5:00pm
THE Aab CVRI Seminar Series

SPEAKER: Jeffrey D. Amack, PhD Associate Professor of Cell and Developmental Biology State University of New York Upstate Medical University Syracuse, NY

TITLE OF TALK: Cilia in vertebrate left-right patterning (zebrafish model) (tentative)

Location:  CVRI Conf. Room # G.11211/G.11213 MRBX/Delmonte Bldg - (Ground floor)

Posted by:  Jacqueline Velazquez, Cardiovascular Research Institute, 16-Mar-17 11:37am ET


April 7, 2017 ( Friday )

3:00pm - 4:00pm
Department of Biology E2G2 Seminar

Emerson Khost, University of Rochester

TBA

Location:  Hutchison Hall, Room 316

Posted by:  Deborah Lawrence, Biology, 30-Jan-17 10:15am ET


April 10, 2017 ( Monday )

12:00pm - 1:00pm
Department of Biology Donut Talk

Dr. Karen Miga, University of California, Santa Cruz

"The dark side of the genome: a high-resolution study of human centromeric regions"

Location:  Hutchison Hall, Lander Auditorium

Posted by:  Deborah Lawrence, Biology, 16-Jan-17 11:13am ET


12:00pm - 1:00pm
Microbiology and Immunology Department Seminar

Nicole Pecora, M.D., Ph.D Assistant Professor, University of Rochester

"Microbial Whole Genome Sequencing in the Clinical Laboratory: Implementation and Applications"

Monday, April 10, 2017 12:00-1:00 PM Upper Auditorium (Room 3-7619)

Hosted by Steve Gill, Ph.D

As microbial whole genome sequencing (WGS) has become more affordable and more accessible it has begun to enter the realm of routine clinical microbiology. Promising applications include outbreak epidemiology and clonality assessment, analysis of resistance and virulence factors, studies of novel organisms, microbiome assessment, and pathogen identification in primary specimens. In particular, WGS analysis of antibiotic resistance has the unique ability to place elements in a genetic context, i.e. chromosome versus plasmid, providing information about transmissibility. In a 3 year pilot study, we assessed the utility of WGS to assess the clonality and resistance genotype of all carbapenem-resistant Enterobacteriaceae (CRE) in a Boston area hospital. Combining the genomic data with clinical metadata allowed for a rich picture of institutional antibiotic resistance, including the mobilization apparatus (transposons and plasmids) associated with different genes. Following the pilot study, prospective use of microbial WGS has provided support in numerous clinical situations, including the characterization of a series of NDM-bearing organisms, a rare but increasing component of the CRE landscape in the United States. In summary, while challenges remain to develop customized analytical pipelines as well as a clinical reporting structure, WGS is poised to make a dramatic change in the clinical microbiology laboratory and the practice of infection control.

Location:  Upper Auditorium 3-7619

Posted by:  Jack McMahon, Micro & Immunolgy, 16-Mar-17 10:23am ET


April 12, 2017 ( Wednesday )

4:00pm - 5:00pm
CVRI Seminar Series

SPEAKER: Arshad Rahman, PhD Associate Professor - Department of Pediatrics, Neonatology University of Rochester Medical Center School of Medicine and Dentistry

TITLE OF TALK: Mechanisms of endothelial cell inflammation and barrier disruption in acute lung injury

Location:  CVRI Conf. Room # G.11211/G.11213 MRBX/Delmonte Bldg - (Ground floor)

Posted by:  Jacqueline Velazquez, Cardiovascular Research Institute, 16-Mar-17 11:44am ET


April 14, 2017 ( Friday )

1:00pm
PhD Thesis Defense

Tian Zhang, University of Rochester

"Global Quantification of Proteome Dynamics"

Location:  Goergen Hall 108

Posted by:  Brenna Rybak, Biology, 24-Mar-17 2:10pm ET


3:00pm - 4:00pm
Department of Biology E2G2 Seminar

Cara Brand, University of Rochester

TBA

Location:  Hutchison Hall, Room 316

Posted by:  Deborah Lawrence, Biology, 30-Jan-17 10:16am ET


April 17, 2017 ( Monday )

12:00pm - 1:00pm
Department of Biology Donut Talk

Dr. Stefan Horvath, UCLA, David Geffen School of Medicine

"Epigenetic clock in humans and other species"


Location:  Hutchison Hall, Lander Auditorium

Posted by:  Deborah Lawrence, Biology, 3-Feb-17 11:23am ET


April 21, 2017 ( Friday )

3:00pm - 4:00pm
Department of Biology E2G2 Seminar

Dr. Jeffrey Good, University of Montana

Sex chromosome evolution and speciation

Location:  Hutchison Hall, Room 316

Posted by:  Deborah Lawrence, Biology, 23-Feb-17 11:29am ET


April 24, 2017 ( Monday )

12:00pm - 1:00pm
Department of Biology Donut Talk Seminar

Dr. Floris Bosveld, Institute Curie (Paris, France)

"Spindle positioning and centrosome inheritance in epithelial tissue"

Location:  Hutchison Hall, Lander Auditorium

Posted by:  Deborah Lawrence, Biology, 27-Jan-17 1:26pm ET


April 26, 2017 ( Wednesday )

7:00pm
Precision MedicineóNotre Dameís Bold Initiative to Lead the 21st Century Revolution in Personalized Healthcare

Paul W. Bohn, Ph.D.
University of Notre Dame Arthur J. Schmitt Professor of Chemical and Biomolecular Engineering Professor of Chemistry and Biochemistry Director, Advanced Diagnostics & Therapeutics Initiative

Contemporary therapeutics rests principally on epidemiology, large-scale trials of therapeutic interventions, and average responses. Precision medicine moves beyond this paradigm by delivering the right treatment to the right person at the right time. It brings together clinicians and basic researchers to identify - and learn how to use - individual/personal "molecular keys" that combine an individual's genomic makeup with time/space localized information about organ/tissue-specific protein expression (proteomics) and function (metabolomics). This information, obtained ideally from small samples - even a single cell – could form the basis for earlier, potentially pre-symptomatic diagnoses and individually-tailored therapies to enhance the effectiveness of treatment. This talk will describe Notre Dame's holistic approach to precision medicine, going well beyond genetic information to target a broad panel of molecular markers, including proteins and metabolites, and the development of new and potentially revolutionary new biomedical technologies, like electrokinetic micro-RNA chips, clinical instruments printed on paper, and ultra high efficiency and sensitivity separations to analyze single somatic cells, i.e. chemical cytometry.

Click here for a video on Dr. Bohn's work. For additional information please visit http://rochester.undclub.org

Location:  Adolph Auditorium University of Rochester Medical Center

Posted by:  Susanne Pallo, Clinical & Translational Sciences Inst, 3-Mar-17 1:44pm ET


April 28, 2017 ( Friday )

3:00pm - 4:00pm
Department of Biology E2G2 Seminar

Longjun Wu, University of Rochester

TBA

Location:  Hutchison Hall, Room 316

Posted by:  Deborah Lawrence, Biology, 30-Jan-17 10:17am ET

 
 
https://www.urmc.rochester.edu/calendar/index.html