Research Meetings
March through April 2015


March 5, 2015 ( Thursday )

12:30pm - 1:30pm
Pharmacology and Physiology Colloquium Seminar

Rahul Chandrasekhar
(Graduate Student in the Laboratory of Dr. David I. Yule)

"Novel Insights Into Inositol 1,4,5 Trisphosphate (InsP3) Receptor Regulation Using Concatenated Homo and Heteromeric Constructs

Location:  Anders Room (4-6912)

Posted by:  Sharon Runion, 2-Mar-15 10:33am ET


March 6, 2015 ( Friday )

3:00pm - 4:00pm
Department of Biology EEB Seminar

Dr. Martine Zilversmit, NIH - Laboratory of Malaria and Vector Research

"The evolutionary genomics of malaria: mutation, duplication, and recombination"

Location:  Hutchison 316

Posted by:  Deborah Lawrence, Biology, 21-Jan-15 10:54am ET


March 9, 2015 ( Monday )

12:00pm - 1:00pm
Department of Microbiology & Immunology Seminar Series

Ted Clark, Ph.D.

Professor of Parasitology and Immunology, Department of Microbiology & Immunology, Cornell University College of Veterinary Medicine

"Regulated secretion in Tetrahymena : novel strategies for the production of recombinant particle-based vaccines"

Host: Jacques Robert

Seminar Abstract: We have a long-standing interest in host-pathogen interactions and prophylatic methods of infectious disease control. In this regard, we have spent considerable effort developing the common pondwater ciliate, Tetrahymena thermophila, as an alternative platform for the manufacture of recombinant subunit vaccines. Tetrahymena has a number of biological features that make it particularly well suited to the production of difficult to express membrane and secreted proteins. Recently, we have found that endogenous proteins that traffic via the regulated secretory pathway of these cells can drive the assembly of vaccine antigens into nanometer-sized particles resembling VLPs both in vivo and in vitro. Application of this technology to the development of transmission-blocking vaccines for malaria will be discussed.

http://www.vet.cornell.edu/microbiology/faculty/Clark/

Location:  Upper Auditorium, Rm 3-7619

Posted by:  Nicole Beaumont, Micro & Immunolgy, 10-Feb-15 1:18pm ET


March 11, 2015 ( Wednesday )

10:00am - 11:00am
Pharmacology and Physiology Faculty Recruitment Seminar

Huan Ma,Ph.D.

Postdoctoral Fellow
Neuroscience Institute
NYU School of Medicine
New York, NY

"Shuttling Excitation to Transcription: Novel Mechanisms and Implications for Disease"

Location:  Room K-207 (2-6408)

Posted by:  Sharon Runion, 5-Mar-15 2:26pm ET


4:00pm - 5:00pm
THE Aab CVRI Seminar Series

SPEAKER: Ellie Tzima, Ph.D. University of North Carolina School of Medicine

TITLE OF TALK: Vascular "Mechanotransduction: from the protein to the vessel"

Location:  CVRI Conf. Room A105 - 211 Bailey Road, West Henrietta, NY

Posted by:  Jacqueline Velazquez, Cardiovascular Research Institute, 5-Mar-15 2:33pm ET


March 12, 2015 ( Thursday )

9:30am - 10:30am
Pharmacology and Physiology Thesis Defense Seminar

Qiuyu Zhu
(Dr. Charles J. Lowenstein, Advisor)

"the Role of STXBP5, VAMP8, and SNAP23 in Endothelial Exocytosis"

Location:  Adolph Auditorium (1-7619)

Posted by:  Sharon Runion, 4-Mar-15 1:41pm ET


March 16, 2015 ( Monday )

12:00pm - 1:00am
Department of Microbiology & Immunology Seminar Series

Christine O'Connor, Ph.D.

Assistant Professor, Department of Microbiology & Immunology, The Witebsky Center for Microbial Pathogenesis & Immunology School of Medicine and Biomedical Sciences, University at Buffalo – SUNY

" The role of human cytomegalovirus GPCRs during infection"

Host: Brian Ward

Seminar Abstract: Infection with human cytomegalovirus (HCMV) is lifelong, during which the virus remains latent in the hematopoietic system of the host. Approximately 80% of the population in developed countries is HCMV-positive by age 40, although viral infection is kept sequestered by a healthy individual's competent immune system. However, HCMV reactivation from latency into the lytic cycle results in devastating consequences within immunosuppressed hosts. Our laboratory studies the contribution of the four viral encoded G-protein coupled receptors (vGPCRs) to HCMV pathogenesis. We have shown that these vGPCRs are important to lytic replication in cell types crucial for in vivo pathogenesis and that they contribute to successful lytic infection in a cell-type specific manner. We have also begun to interrogate the role of these vGPCRs during latent infection and have found one of the vGPCRs is a key component in promoting a successful latent infection, an avenue that we are currently pursuing.

http://medicine.buffalo.edu/content/medicine/faculty/profile.html?ubit=oconnorc


Location:  Upper Auditorium, Rm 3-7619

Posted by:  Nicole Beaumont, Micro & Immunolgy, 10-Feb-15 2:01pm ET


12:00pm - 1:00pm
Department of Biology Donut Talk

Dr. Victoria Meller, Wayne State University

"The long and the short of it: non-coding RNA and whole chromosome recognition"

Location:  Hutchison Hall - Lander Auditorium

Posted by:  Deborah Lawrence, Biology, 15-Jan-15 10:12am ET


March 18, 2015 ( Wednesday )

12:30pm - 1:30pm
Bagel Talk Series 2014-2015

Szilvia Arany, D.M.D., Ph.D.

Research Assistant Professor of Dentistry in the Center for Oral Biology

"Preventive strategy for salivary gland dysfunction after radioiodine therapy"


Location:  Center for Oral Biology Conference Room, G9654, KMRB

Posted by:  Nicole Beaumont, Micro & Immunolgy, 3-Mar-15 7:37am ET


March 23, 2015 ( Monday )

12:00pm - 1:00pm
Department of Biology Donut Talk

Dr. Katherine Pollard, The Gladstone Institute

TBA

Location:  Hutchison Hall - Lander Auditorium

Posted by:  Deborah Lawrence, Biology, 15-Jan-15 10:15am ET


12:00pm - 1:00pm
Department of Microbiology & Immunology Seminar Series

Heran Darwin, Ph.D.

Professor, Department of Microbiology, New York University Langone Medical Center

" Mycobacterium tuberculosis proteasomes, pupylation and...plant hormones? "

Host: Scott Butler

Seminar Abstract: Prokaryotic ubiquitin-like protein (Pup) is functionally analogous to Ub in Mycobacterium tuberculosis (Mtb) as it delivers proteins to the Mtb proteasome for degradation. Although it has long been known that the Pup-proteasome system is required for resistance to nitric oxide (NO) and virulence, we have only recently elucidated the mechanism of protection against NO. I will discuss how proteasome function regulates the synthesis of plant hormones, the accumulation of which is detrimental to one of the world's deadliest pathogens.

http://microbiology-parasitology.med.nyu.edu/heran-darwin

Location:  Upper Auditorium, Rm 3-7619

Posted by:  Nicole Beaumont, Micro & Immunolgy, 13-Feb-15 4:06pm ET


March 25, 2015 ( Wednesday )

4:00pm - 5:00pm
THE Aab CVRI Seminar Series

SPEAKER: Jim Palis, MD

TITLE OF TALK: "Erythropoiesis and thrombopoiesis"

Location:  CvRI Conf. Room A105 - 211 Bailey Road, West Henrietta, NY

Posted by:  Jacqueline Velazquez, Cardiovascular Research Institute, 13-Feb-15 1:29pm ET


March 30, 2015 ( Monday )

12:00pm - 1:00pm
Department of Microbiology & Immunology Seminar Series

Jose R Conejo-Garcia, MD, PhD


Professor and Program Leader, Tumor Microenvironment and Metastasis Program, The Wistar Institute

" Microbial driven TLR5-dependent signaling governs distal malignant progression through systemic tumor-promoting inflammation "

Host: Edith Lord

Seminar Abstract: The dominant R392X TLR5 polymorphism abrogates flagellin responses in >7% of humans. We report that TLR5-dependent commensal bacteria drive malignant progression at (distal) extra-mucosal locations by promoting systemic IL-6 up-regulation, which drives MDSC mobilization. Mechanistically, expanded granulocytic MDSCs cause γδ lymphocytes in TLR5+/+ tumors to secrete galectin-1, dampening anti-tumor immunity and accelerating malignant progression. In contrast, IL-17 is consistently up-regulated in TLR5-unresponsive tumor-bearing individuals, but only accelerates malignant progression in IL-6-unresponsive tumors. Importantly, depletion of commensal bacteria abrogates any TLR5-dependent differences in tumor growth. Contrasting differences in inflammatory cytokines and malignant evolution are recapitulated in TLR5-responsive/unresponsive ovarian and breast cancer patients. Therefore, inflammation, anti-tumor immunity and the clinical outcome of cancer patients are influenced by a common TLR5 polymorphism.

http://www.wistar.org/our-science/scientists/jose-r-conejo-garcia-md-phd

Location:  Upper Auditorium, Rm 3-7619

Posted by:  Nicole Beaumont, Micro & Immunolgy, 2-Mar-15 10:53am ET


April 1, 2015 ( Wednesday )

4:00pm - 5:00pm
THE Aab CVRI Seminar Series

SPEAKER: Gloria S. Pryhuber, MD

TITLE OF TALK: "Inflammatory Lung Disease"

Location:  CVRI Conf. Room A105 - 211 Bailey Road, West Henrietta, NY

Posted by:  Jacqueline Velazquez, Cardiovascular Research Institute, 13-Feb-15 1:30pm ET


April 3, 2015 ( Friday )

3:00pm - 4:00pm
Department of Biology EEB Seminar

Cara Brand, University of Rochester

TBA

Location:  Hutchison 316

Posted by:  Deborah Lawrence, Biology, 23-Jan-15 3:14pm ET


April 6, 2015 ( Monday )

12:00pm - 1:00pm
Department of Biology Donut Talk

Dr. Raul Mostoslavsky, Harvard University

"Linking metabolism with epigenetics and cancer: SIRT6 provides some clues"

Location:  Hutchison Hall - Lander Auditorium

Posted by:  Deborah Lawrence, Biology, 15-Jan-15 10:17am ET


April 8, 2015 ( Wednesday )

4:00pm - 5:00pm
THE Aab CVRI Seminar Series

SPEAKER: Elena Galkina, MD Eastern Virginia Medical School

TITLE OF TALK: T cell fate in atherosclerosis

Location:  Aab CVRI Conf. Room A105, 211 Bailey Road West Henritta, NY

Posted by:  Jacqueline Velazquez, Cardiovascular Research Institute, 13-Feb-15 11:59am ET


4:00pm - 5:00pm
THE Aab CVRI Seminar Series

SPEAKER: Elena Galkina, MD Eastern Virginia Medical School

TITLE OF TALK: "T cell fate in atherosclerosis"

Location:  Aab CVRI Conf. Room A105, 211 Bailey Road West Henritta, NY

Posted by:  Jacqueline Velazquez, Cardiovascular Research Institute, 13-Feb-15 11:59am ET


April 10, 2015 ( Friday )

3:00pm - 4:00pm
Department of Biology EEB Seminar

Dr. Ronald Clouse, University of North Carolina at Charlotte

"The surprising histories of three leaf-litter arthropods in the Indo-Pacific: carpenter ants, harvestmen, and schizomids"

Location:  Hutchison 316

Posted by:  Deborah Lawrence, Biology, 19-Jan-15 2:31pm ET


April 13, 2015 ( Monday )

12:00pm - 1:00pm
Department of Biology Donut Talk

Dr. Keith Clay, Indiana University

"Defensive symbiosis in plants and animals"

Location:  Hutchison Hall - Lander Auditorium

Posted by:  Deborah Lawrence, Biology, 15-Jan-15 10:18am ET


April 15, 2015 ( Wednesday )

4:00pm - 5:00pm
The Aab CVRI Seminar Series

SPEAKER: Peter Libby, MD, Harvard Medical School

TITLE OF TALK: Lipids, inflammmation and atherosclerosis" (tentative)

Location:  CVRI Conf. Room A105 - 211 Bailey Road, West Henrietta, NY

Posted by:  Jacqueline Velazquez, Cardiovascular Research Institute, 13-Feb-15 1:32pm ET


April 17, 2015 ( Friday )

3:00am - 4:00am
Department of Biology EEB Seminar

Dr. Philipp Messer, Cornell University

"Understanding the rapid evolution of pesticide and drug resistance"

Location:  Hutchison 316

Posted by:  Deborah Lawrence, Biology, 19-Jan-15 1:53pm ET


April 20, 2015 ( Monday )

8:30am - 5:00pm
Imaging Symposium

Contact Linda Callahan for more information. Linda_Callahan@urmc.rochester.edu

Location:  Class of

Posted by:  Anne Reed, Shared Resource Laboratories, 30-Jan-15 1:21pm ET


12:00pm - 1:00pm
Department of Biology Donut Talk

Dr. William Bohr, NIH

"Nuclear to mitochondrial DNA damage signaling and its role in age associated disease"

Location:  Hutchison Hall - Lander Auditorium

Posted by:  Deborah Lawrence, Biology, 15-Jan-15 10:33am ET


April 22, 2015 ( Wednesday )

4:00pm - 5:00pm
THE Aab CVRI Seminar Series

SPEAKER: William Brown, PhD Cornell University (Itheca)

TITLE OF TALK: "Intracellular membrane trafficking in the secretory and endocytic pathways"

Location:  CVRI Conf. Room A105 - 211 Bailey Road, West Henrietta, NY

Posted by:  Jacqueline Velazquez, Cardiovascular Research Institute, 13-Feb-15 1:34pm ET


April 24, 2015 ( Friday )

3:00pm - 4:00pm
Department of Biology EEB Seminar

Dr. Kevin Thornton, University of California, Irvine

TBA

Location:  Hutchison 316

Posted by:  Deborah Lawrence, Biology, 14-Jan-15 3:49pm ET


April 27, 2015 ( Monday )

12:00pm - 1:00pm
Department of Biology Donut Talk

Dr. Tsan Sam Xiao, Case Western Reserve

"Mechanisms of nucleic acid sensing by innate immune receptors"

Location:  Hutchison Hall - Lander Auditorium

Posted by:  Deborah Lawrence, Biology, 15-Jan-15 10:34am ET


April 29, 2015 ( Wednesday )

4:00pm - 5:00pm
The Aab CVRI Seminar Series

SPEAKER: Samuel Carrell, (HHMI student)

TITLE OF TALK: "TBD"

Location:  CVRI Conf. Room A105 - 211 Bailey Road, West Henrietta, NY

Posted by:  Jacqueline Velazquez, Cardiovascular Research Institute, 13-Feb-15 1:35pm ET

 
 
http://www.urmc.rochester.edu/calendar/index.html