Research Meetings
April through May 2017

May 1, 2017 ( Monday )

12:00pm - 1:00pm
Department of Biology Donut Talk Seminar

Dr. Yang Shi, Harvard University

"Histone and nucleic acid methylation regulation and link to human disease"

Location:  Hutchison Hall, Lander Auditorium

Posted by:  Deborah Lawrence, Biology, 3-Feb-17 11:24am ET

12:00pm - 1:00pm
Microbiology and Immunology Department Seminar

Speaker: George O'Toole, PhD. Professor of Microbiology and Immunology, Dartmouth, Geisel School of Medicine.

Host: Scott Butler

Title: To Build a Biofilm

Abstract: Biofilms are surface-attached microbial communities. c-di-GMP is a conserved dinucleotide signal that regulates biofilm formation by bacteria. Synthesis of c-di-GMP by diguanylate cyclases (DGCs) and its degradation by phosphodiesterases (PDEs) is well established, and progress has also been made in elucidating c-di-GMP output systems. For example, our group has characterized a membrane protein, LapD, which binds c-di-GMP via a degenerate PDE domain; this c-di-GMP receptor regulates localization of the LapA adhesin to the cell surface, which is a critical event for biofilm formation by Pseudomonas fluorescens. A central open question in the field is how bacteria like P. fluorescens and P. aeruginosa, with 50+ proteins that make, break and bind c-di-GMP, coordinate the action of these many proteins to provide a coordinated, c-di-GMP-regulated output. I will discuss recent work from the lab exploring mechanisms of c-di-GMP signaling specificity that impact the control of a biofilm adhesion system that is conserved in 1000+ bacterial genomes.

Location:  Upper Auditorium (Room 3-7619)

Posted by:  Jack McMahon, Micro & Immunolgy, 30-Mar-17 12:24pm ET

May 3, 2017 ( Wednesday )

12:30pm - 1:30pm
Center for Oral Biology Bagel Talks 2017-2018

Paul Dunman, Ph.D.

Associate Professor, Department of Microbiology and Immunology

"Defining RnpA, a Potential Antimicrobial Target"

Location:  COB Conference room, G9654, KMRB

Posted by:  Nicole Beaumont, Center for Oral Biology, 26-Apr-17 9:36am ET

May 8, 2017 ( Monday )

12:00pm - 1:00pm
Department of Biology Donut Talk Seminar

Dr. Vlad Denic, Harvard University

"A membrane-associated autophagy signaling pathway for controlling peroxisome fate"

Location:  Hutchison Hall, Lander Auditorium

Posted by:  Deborah Lawrence, Biology, 27-Mar-17 9:14am ET

May 10, 2017 ( Wednesday )

4:00pm - 5:00pm
The Aab CVRI Seminar Series

SPEAKER: Thomas Mark Michel, MD, PhD Professor of Medicine and Biochemistry, Harvard Medical School Senior Physician in Cardiovascular Medicine, Brigham and Women's Hospital Leadership Council and Director of Clinical Studies, Harvard-MIT MD-PhD Program Co-Director, Leder Human Biology and Translational Medicine Program (HMS) Brigham and Women's Hospital Harvard Medical School Boston, MA

TITLE OF TALK: "Novel roles for reactive oxygen species in cardiovascular signaling"

"Reactive oxygen species have long been associated with pathological oxidative stress in diverse disease states. More recently, the stable ROS hydrogen peroxide has been shown to play critical physiological roles in cardiovascular signaling pathways. This talk will discuss recent discoveries using novel biosensors to dissect the roles of hydrogen peroxide in the modulation of insulin-dependent responses in cardiac myocytes and flow-dependent signaling in the endothelium"

Location:  CVRI Conf. Room # G.11211/G.11213 MRBX/Delmonte Bldg - (Ground floor)

Posted by:  Jacqueline Velazquez, Cardiovascular Research Institute, 18-Apr-17 3:49pm ET

May 25, 2017 ( Thursday )

10:00am - 4:00pm
Aging Research Day

This all-day event will feature a variety of talks on aging research.

Keynote Speaker: Dr. David A. Sinclair, Harvard Medical School & Founding Director of the Paul F. Glenn Center for the Biological Mechanisms of Aging at Harvard.

Location:  Goergen Hall, River Campus, Room 101

Posted by:  Deborah Lawrence, Biology, 30-Mar-17 3:22pm ET